OPM provides spatial arrangements of membrane proteins with respect to the hydrocarbon core of the lipid bilayer.
OPM includes all unique experimental structures of transmembrane proteins and some peripheral proteins and membrane-active peptides (Features).
Each protein is positioned in a lipid bilayer of adjustable thickness by minimizing its transfer energy from water to the membrane (Methods).
OPM provides structural classification and sorting according to different criteria (Classification).
Our calculations are in agreement with experimental studies of 24 transmembrane and 39 peripheral peptides and proteins (Comparison with Experiments).
Positions of all proteins were recalculated in June 2010 using a new implicit solvent model of the lipid bilayer, PPM 2.0 (see methods)In citing the Orientations of Proteins in Membranes (OPM) database please refer to
Please use our web server or we can process your coordinates through email (firstname.lastname@example.org). All information is kept confidential. Orientation of membrane protein cannot be predicted if all its membrane-anchoring elements are missing or disordered.2. Errors in orientation or experimental verification description?
Please contact us.