PDB ID or protein name

Membrane Protein Lipid Composition Atlas

1. Archaebacterial membrane (94 proteins)
2. Bacterial Gram-negative inner membrane (494 proteins)
3. Bacterial Gram-negative outer membrane (227 proteins)
4. Bacterial Gram-positive outer membrane (10 proteins)
5. Bacterial Gram-positive plasma membrane (144 proteins)
6. Chloroplast inner membrane (3 proteins)
7. Chloroplast outer membrane (2 proteins)
8. Cytoplasmic granule membrane (1 protein)
9. Endoplasmic reticulum membrane (209 proteins)
10. Endosome membrane (56 proteins)
11. Eukaryotic plasma membrane (847 proteins)
12. Golgi membrane (35 proteins)
13. Lysosome membrane (24 proteins)
14. Mitochondrial inner membrane (80 proteins)
15. Mitochondrial outer membrane (33 proteins)
16. Nuclear inner membrane (5 proteins)
17. Nuclear outer membrane (6 proteins)
18. Peroxisome membrane (11 proteins)
19. Secreted (983 proteins)
20. Thylakoid membrane (42 proteins)
21. Undefined (118 proteins)
22. Vacuole membrane (28 proteins)
23. Vesicle membrane (22 proteins)
24. Viral membrane (92 proteins)

Lipid Composition in Archaebacterial membrane

Archaebacterial membrane

corner lipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipid corner
lipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipid
3d31 » Molybdate transporter ModBC, open state 3d31 » Molybdate transporter ModBC, open state
29.8 ± 1.5 Å
spacer 1rh5 » Protein translocase SecY, closed state, mutant
29.0 ± 1.1 Å
1rh5 » Protein translocase SecY, closed state, mutant
lipid
lipid
  spacer   lipid
lipid
1ors » Potassium channel KvAP, sensor domain 1ors » Potassium channel KvAP, sensor domain
31.5 ± 2.2 Å
spacer 1orq » Potassium channel KvAP, complex with Fab
29.3 ± 1.6 Å
1orq » Potassium channel KvAP, complex with Fab
lipid
lipid
  spacer   lipid
lipid
1m0l » Bacteriorhodopsin 1m0l » Bacteriorhodopsin
31.8 ± 1.1 Å
spacer 1h2s » Sensory rhodopsin II, tetramer, structure 1
30.5 ± 1.1 Å
1h2s » Sensory rhodopsin II, tetramer, structure 1
lipid
lipid
  spacer   lipid
lipid
1e12 » Halorhodopsin 1e12 » Halorhodopsin
31.8 ± 1.4 Å
spacer 1uaz » Archaerhodopsin-1
31.8 ± 1.3 Å
1uaz » Archaerhodopsin-1
lipid
lipid
  spacer   lipid
lipid
1iw6 » Bacteriorhodopsin, K state, with lipids 1iw6 » Bacteriorhodopsin, K state, with lipids
30.0 ± 0.6 Å
spacer 2zzl » Bacteriorhodopsin, trimer, complex with annular lipids
29.8 ± 0.6 Å
2zzl » Bacteriorhodopsin, trimer, complex with annular lipids
lipid
lipid
  spacer   lipid
lipid
1h68 » Sensory rhodopsin II, monomer 1h68 » Sensory rhodopsin II, monomer
30.3 ± 1.5 Å
spacer 1py6 » Bacteriorhodopsin, monomer
29.6 ± 2.2 Å
1py6 » Bacteriorhodopsin, monomer
lipid
lipid
  spacer   lipid
lipid
2b2f » Ammonium transporter Amt-1 2b2f » Ammonium transporter Amt-1
28.9 ± 0.7 Å
spacer 1vgo » Archaerhodopsin-2, monomer
30.7 ± 1.3 Å
1vgo » Archaerhodopsin-2, monomer
lipid
lipid
  spacer   lipid
lipid
2a0l » Potassium channel KvAP 2a0l » Potassium channel KvAP
29.5 ± 1.1 Å
spacer 2f2b » Aquaporin AqpM
29.0 ± 0.8 Å
2f2b » Aquaporin AqpM
lipid
lipid
  spacer   lipid
lipid
3bo0 » Protein translocase SecY, complex with ribosome 2 3bo0 » Protein translocase SecY, complex with ribosome 2
29.6 ± 1.2 Å
spacer 3s0x » Peptidase A24B, FlaK domain protein
31.8 ± 1.6 Å
3s0x » Peptidase A24B, FlaK domain protein
lipid
lipid
  spacer   lipid
lipid
1vff » Beta-glycosidase 1vff » Beta-glycosidase
3.9 ± 1.6 Å
spacer 3wbn » H+-driven MATE exporter, outward-open, straight conformation
31.8 ± 1.4 Å
3wbn » H+-driven MATE exporter, outward-open, straight conformation
lipid
lipid
  spacer   lipid
lipid
3vvo » H+-driven MATE exporter, outward-open, 3vvo » H+-driven MATE exporter, outward-open, "bent" conformation
31.4 ± 1.1 Å
spacer 3vvp » H+-driven MATE exporter, outward-open, with nonpeptide inhibitor
29.8 ± 1.3 Å
3vvp » H+-driven MATE exporter, outward-open, with nonpeptide inhibitor
lipid
lipid
  spacer   lipid
lipid
3ne2 » Aquaporin AqpM 3ne2 » Aquaporin AqpM
31.2 ± 1.3 Å
spacer 3j08 » Copper efflux ATPase, CopA
27.6 ± 0.8 Å
3j08 » Copper efflux ATPase, CopA
lipid
lipid
  spacer   lipid
lipid
2onk » Molybdate transporter ModBC, open state 2onk » Molybdate transporter ModBC, open state
32.0 ± 1.7 Å
spacer 3bpp » Membrane protease specific for a stomatin homolog, monomer
4.0 ± 0.4 Å
3bpp » Membrane protease specific for a stomatin homolog, monomer
lipid
lipid
  spacer   lipid
lipid
2nwl » Proton glutamate symport protein, outward-facing state 1 2nwl » Proton glutamate symport protein, outward-facing state 1
29.8 ± 1.3 Å
spacer 1ap9 » Bacteriorhodopsin, from cubic phase
30.6 ± 1.2 Å
1ap9 » Bacteriorhodopsin, from cubic phase
lipid
lipid
  spacer   lipid
lipid
2ei4 » Archaerhodopsin-2, trimeric 2ei4 » Archaerhodopsin-2, trimeric
30.5 ± 1.2 Å
spacer 3b4r » Site-2 protease (S2P) metalloprotease
29.9 ± 1.4 Å
3b4r » Site-2 protease (S2P) metalloprotease
lipid
lipid
  spacer   lipid
lipid
3gia » Amino acid transporter ApcT, inward-facing conformation 3gia » Amino acid transporter ApcT, inward-facing conformation
29.9 ± 1.4 Å
spacer 3kbc » Proton glutamate symport protein, inward-facing state 1
28.1 ± 0.9 Å
3kbc » Proton glutamate symport protein, inward-facing state 1
lipid
lipid
  spacer   lipid
lipid
3a7k » Halorhodopsin 3a7k » Halorhodopsin
33.8 ± 1.4 Å
spacer 2yxr » Protein translocase SecY, mutant with full-plug (TM2a) deletion
29.7 ± 0.8 Å
2yxr » Protein translocase SecY, mutant with full-plug (TM2a) deletion
lipid
lipid
  spacer   lipid
lipid
2kyh » Potassium channel KvAP, sensor domain, NMR model 2kyh » Potassium channel KvAP, sensor domain, NMR model
28.6 ± 1.4 Å
spacer 3ldc » Calcium-gated potassium channel MthK
29.8 ± 0.8 Å
3ldc » Calcium-gated potassium channel MthK
lipid
lipid
  spacer   lipid
lipid
3mp7 » Protein translocase SecY, partialy open 3mp7 » Protein translocase SecY, partialy open
30.1 ± 1.0 Å
spacer 3dkn » Protein translocase SecY, complex with ribosome 1
27.8 ± 1.8 Å
3dkn » Protein translocase SecY, complex with ribosome 1
lipid
lipid
  spacer   lipid
lipid
1jji » Carboxylesterase (EstA) 1jji » Carboxylesterase (EstA)
2.8 ± 1.0 Å
spacer 3cnu » Uncharacterized protein
7.6 ± 1.7 Å
3cnu » Uncharacterized protein
lipid
lipid
  spacer   lipid
lipid
3j09 » Copper efflux ATPase, CopA, alternative conformation 3j09 » Copper efflux ATPase, CopA, alternative conformation
27.0 ± 0.1 Å
spacer 4a2n » Integral Membrane Methyltransferase
30.6 ± 1.2 Å
4a2n » Integral Membrane Methyltransferase
lipid
lipid
  spacer   lipid
lipid
1l0q » Surface layer protein 1l0q » Surface layer protein
3.1 ± 0.9 Å
spacer 3v5u » Sodium/calcium exchanger, structure 1
29.8 ± 0.9 Å
3v5u » Sodium/calcium exchanger, structure 1
lipid
lipid
  spacer   lipid
lipid
3viv » Membrane protease specific for a stomatin homolog, dimer 3viv » Membrane protease specific for a stomatin homolog, dimer
4.5 ± 0.4 Å
spacer 4ev6 » Magnesium transport protein CorA
28.4 ± 1.5 Å
4ev6 » Magnesium transport protein CorA
lipid
lipid
  spacer   lipid
lipid
4hyg » Intramembrane aspartate protease 4hyg » Intramembrane aspartate protease
31.8 ± 0.3 Å
spacer 1fbk » Bacteriorhodopsin, different loop conformaton
30.0 ± 1.2 Å
1fbk » Bacteriorhodopsin, different loop conformaton
lipid
lipid
  spacer   lipid
lipid
2yxq » Protein translocase SecY, mutant with half-plug (TM2a) deletion 2yxq » Protein translocase SecY, mutant with half-plug (TM2a) deletion
29.2 ± 1.1 Å
spacer 1rhz » Protein translocase SecY, closed state
29.4 ± 1.0 Å
1rhz » Protein translocase SecY, closed state
lipid
lipid
  spacer   lipid
lipid
2nww » Proton glutamate symport protein, outward-facing state 2 2nww » Proton glutamate symport protein, outward-facing state 2
30.6 ± 0.6 Å
spacer 3v8g » Proton glutamate symport protein, mixed inward/outward trimer
29.8 ± 1.0 Å
3v8g » Proton glutamate symport protein, mixed inward/outward trimer
lipid
lipid
  spacer   lipid
lipid
3v5s » Sodium/calcium exchanger, structure 2 3v5s » Sodium/calcium exchanger, structure 2
29.6 ± 1.6 Å
spacer 4fbz » Deltarhodopsin
31.6 ± 0.8 Å
4fbz » Deltarhodopsin
lipid
lipid
  spacer   lipid
lipid
3vvk » Halorhodopsin, different conformation 3vvk » Halorhodopsin, different conformation
33.6 ± 1.1 Å
spacer 4kpp » H+/Ca2+ exchanger
29.8 ± 1.4 Å
4kpp » H+/Ca2+ exchanger
lipid
lipid
  spacer   lipid
lipid
5dwy » Proton/glutamate symporter, apo 5dwy » Proton/glutamate symporter, apo
30.8 ± 0.6 Å
spacer 4mlb » H+-driven MATE exporter, outward-open, different conformation
30.2 ± 1.2 Å
4mlb » H+-driven MATE exporter, outward-open, different conformation
lipid
lipid
  spacer   lipid
lipid
1vvk » Protein translocase SecY, complex with ribosome 3 1vvk » Protein translocase SecY, complex with ribosome 3
28.6 ± 0.7 Å
spacer 3wak » Transmembrane oligosaccharyl transferase
29.8 ± 0.6 Å
3wak » Transmembrane oligosaccharyl transferase
lipid
lipid
  spacer   lipid
lipid
4od5 » 4-hydroxybenzoate octaprenyltransferase 4od5 » 4-hydroxybenzoate octaprenyltransferase
29.8 ± 0.9 Å
spacer 4jr8 » Cruxrhodopsin-3
31.8 ± 1.2 Å
4jr8 » Cruxrhodopsin-3
lipid
lipid
  spacer   lipid
lipid
4o6m » CDP-alcohol phosphatidyltransferase 4o6m » CDP-alcohol phosphatidyltransferase
30.0 ± 1.3 Å
spacer 4p19 » Proton glutamate symport protein, inward-facing state 2
30.6 ± 1.0 Å
4p19 » Proton glutamate symport protein, inward-facing state 2
lipid
lipid
  spacer   lipid
lipid
5cfy » Proton glutamate symport protein, outward-facing state 3 5cfy » Proton glutamate symport protein, outward-facing state 3
29.8 ± 0.3 Å
spacer 4mnd » Bifunctional IPC transferase and DIPP synthase
30.2 ± 1.0 Å
4mnd » Bifunctional IPC transferase and DIPP synthase
lipid
lipid
  spacer   lipid
lipid
4tq4 » Bacteriochlorophyll synthase 4tq4 » Bacteriochlorophyll synthase
29.2 ± 1.5 Å
spacer 4oye » Proton glutamate symport protein, outward-facing state 4
28.2 ± 0.6 Å
4oye » Proton glutamate symport protein, outward-facing state 4
lipid
lipid
  spacer   lipid
lipid
3w9k » Thermoacidophile-specific fatty acid carrier 3w9k » Thermoacidophile-specific fatty acid carrier
2.7 ± 1.4 Å
spacer 4czb » Na+/H+ antiporter 1, inward-open conformation
27.2 ± 0.5 Å
4czb » Na+/H+ antiporter 1, inward-open conformation
lipid
lipid
  spacer   lipid
lipid
4d0a » Na+/H+ antiporter 1, outward-open conformation 4d0a » Na+/H+ antiporter 1, outward-open conformation
28.4 ± 1.0 Å
spacer 4cz8 » Na+/H+ antiporter, structure 1
29.8 ± 0.9 Å
4cz8 » Na+/H+ antiporter, structure 1
lipid
lipid
  spacer   lipid
lipid
4cz9 » Na+/H+ antiporter, structure 2 4cz9 » Na+/H+ antiporter, structure 2
27.2 ± 0.8 Å
spacer 4pxk » Bacteriorhodopsin-I
31.8 ± 1.4 Å
4pxk » Bacteriorhodopsin-I
lipid
lipid
  spacer   lipid
lipid
4x2s » Proton glutamate symport protein, inward-facing state 3 4x2s » Proton glutamate symport protein, inward-facing state 3
27.0 ± 0.7 Å
spacer 4qi1 » Bacteriorhodopsin-I
31.8 ± 1.2 Å
4qi1 » Bacteriorhodopsin-I
lipid
lipid
  spacer   lipid
lipid
4y7j » Mechanosensitive channel MscL, expanded state 4y7j » Mechanosensitive channel MscL, expanded state
26.8 ± 0.0 Å
spacer 4y7k » Mechanosensitive channel MscL, closed state
31.8 ± 0.1 Å
4y7k » Mechanosensitive channel MscL, closed state
lipid
lipid
  spacer   lipid
lipid
5c8j » YidC-like protein 5c8j » YidC-like protein
29.8 ± 1.4 Å
spacer 4wav » Bacteriorhodopsin-I
30.0 ± 2.1 Å
4wav » Bacteriorhodopsin-I
lipid
lipid
  spacer   lipid
lipid
5hwy » Sodium/calcium exchanger, structure 3 5hwy » Sodium/calcium exchanger, structure 3
29.0 ± 1.7 Å
spacer 2n4x » Cytochrome C-type biogenesis protein (CcdA)
29.0 ± 2.0 Å
2n4x » Cytochrome C-type biogenesis protein (CcdA)
lipid
lipid
  spacer   lipid
lipid
3j1r » Archaeal flagellin, single helix 3j1r » Archaeal flagellin, single helix
33.4 ± 4.4 Å
spacer 5kyh » Archaeal flagellin
37.4 ± 2.0 Å
5kyh » Archaeal flagellin
lipid
lipid
  spacer   lipid
lipid
5e9s » Proton/glutamate symporter, substrate-bound 5e9s » Proton/glutamate symporter, substrate-bound
31.4 ± 0.6 Å
spacer 5h35 » TRIC cation channel
27.4 ± 0.8 Å
5h35 » TRIC cation channel
lipid
lipid
  spacer   lipid
lipid
5jje » Sensory rhodopsin II, tetramer, structure 2 5jje » Sensory rhodopsin II, tetramer, structure 2
30.2 ± 0.8 Å
spacer 5wud » TRIC cation channel, structure 1
28.2 ± 1.0 Å
5wud » TRIC cation channel, structure 1
lipid
lipid
  spacer   lipid
lipid
5wue » TRIC cation channel, structure 2 5wue » TRIC cation channel, structure 2
28.2 ± 0.4 Å
spacer 5o4u » Flagellin
35.0 ± 3.4 Å
5o4u » Flagellin
lipid
lipid
  spacer   lipid
lipid
5vn7 » Bacteriorhodopsin, dimer 5vn7 » Bacteriorhodopsin, dimer
31.0 ± 0.6 Å
spacer 5mlz » Dolichyl phosphate mannose synthase, structure 1
30.6 ± 1.0 Å
5mlz » Dolichyl phosphate mannose synthase, structure 1
lipid
lipid
  spacer   lipid
lipid
5mm0 » Dolichyl phosphate mannose synthase, structure 2 5mm0 » Dolichyl phosphate mannose synthase, structure 2
30.2 ± 1.0 Å
spacer 5mm1 » Dolichyl phosphate mannose synthase, structure 3
30.6 ± 1.0 Å
5mm1 » Dolichyl phosphate mannose synthase, structure 3
corner Archaebacterial membrane corner
Membrane Lipid Composition
Nat Rev Mol Cell Biol. 2008 Feb;9(2):112-24. Membrane lipids: where they are and how they behave.