PDB ID or protein name

Membrane Protein Lipid Composition Atlas

1. Archaebacterial membrane (96 proteins)
2. Bacterial Gram-negative inner membrane (524 proteins)
3. Bacterial Gram-negative outer membrane (240 proteins)
4. Bacterial Gram-positive outer membrane (11 proteins)
5. Bacterial Gram-positive plasma membrane (146 proteins)
6. Chloroplast inner membrane (3 proteins)
7. Chloroplast outer membrane (2 proteins)
8. Cytoplasmic granule membrane (1 protein)
9. Endoplasmic reticulum membrane (232 proteins)
10. Endosome membrane (61 proteins)
11. Eukaryotic plasma membrane (904 proteins)
12. Golgi membrane (40 proteins)
13. Lysosome membrane (35 proteins)
14. Mitochondrial inner membrane (89 proteins)
15. Mitochondrial outer membrane (33 proteins)
16. Nuclear inner membrane (5 proteins)
17. Nuclear outer membrane (6 proteins)
18. Peroxisome membrane (11 proteins)
19. Secreted (1045 proteins)
20. Thylakoid membrane (46 proteins)
21. Undefined (132 proteins)
22. Vacuole membrane (29 proteins)
23. Vesicle membrane (24 proteins)
24. Viral membrane (94 proteins)

Lipid Composition in Endoplasmic reticulum membrane

Cell/Species PC % PE % PI % PS % PA % CL % Sph % Ch % CB % SL % PI+PS % PI+LPE % LPC % PG %
Rat Liver (male Wistar)
Rattus norvegicus
53.0 20.2 - - - - 3.7 - - - 14.1 - - -
Barley Roots
Hordeum vulgare
58.0 20.9 - 1.4 1.0 - - - - - - 2.2 6.4
Light Microsomes
Saccharomyces cerevisiae
51.3 33.4 7.5 6.6 0.2 0.4 - - - - - - - -

Endoplasmic reticulum membrane

corner lipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipid corner
lipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipid
3ar2 » Calcium ATPase, E1-2Ca state, conformation 1 3ar2 » Calcium ATPase, E1-2Ca state, conformation 1
29.6 ± 0.9 Å
spacer 1wpg » Calcium ATPase, E2-Pi state, conformation 1
30.6 ± 1.1 Å
1wpg » Calcium ATPase, E2-Pi state, conformation 1
lipid
lipid
  spacer   lipid
lipid
1t5s » Calcium ATPase, E1-ATP state 1t5s » Calcium ATPase, E1-ATP state
29.7 ± 1.6 Å
spacer 2zbd » Calcium ATPase, E1P-ADP state
31.8 ± 1.4 Å
2zbd » Calcium ATPase, E1P-ADP state
lipid
lipid
  spacer   lipid
lipid
1p49 » Steryl-sulfatase 1p49 » Steryl-sulfatase
29.6 ± 1.1 Å
spacer 4yl3 » Microsomal prostaglandin E synthase 1, structure 3
29.8 ± 0.7 Å
4yl3 » Microsomal prostaglandin E synthase 1, structure 3
lipid
lipid
  spacer   lipid
lipid
1mt5 » Fatty acid amide hydrolase 1mt5 » Fatty acid amide hydrolase
11.1 ± 0.2 Å
spacer 1cx2 » Prostaglandin H2 synthase-2 (cyclooxygenase)
9.7 ± 0.4 Å
1cx2 » Prostaglandin H2 synthase-2 (cyclooxygenase)
lipid
lipid
  spacer   lipid
lipid
1zll » Phospholamban, pentamer 1zll » Phospholamban, pentamer
30.5 ± 1.4 Å
spacer 2agv » Calcium ATPase, E2 state (Ca-free), conformation 1
29.7 ± 2.2 Å
2agv » Calcium ATPase, E2 state (Ca-free), conformation 1
lipid
lipid
  spacer   lipid
lipid
1jdm » Sarcolipin 1jdm » Sarcolipin
29.6 ± 2.4 Å
spacer 1q4g » Prostaglandin H2 synthase-1
8.9 ± 0.4 Å
1q4g » Prostaglandin H2 synthase-1
lipid
lipid
  spacer   lipid
lipid
1w6k » Lanosterol synthase 1w6k » Lanosterol synthase
7.6 ± 1.0 Å
spacer 1nr6 » Cytochrome P450 2C5
10.6 ± 1.0 Å
1nr6 » Cytochrome P450 2C5
lipid
lipid
  spacer   lipid
lipid
1suo » Cytochrome P450 2B4, closed state 1 1suo » Cytochrome P450 2B4, closed state 1
4.6 ± 1.3 Å
spacer 1pq2 » Cytochrome P450 2C8
3.8 ± 1.8 Å
1pq2 » Cytochrome P450 2C8
lipid
lipid
  spacer   lipid
lipid
1og5 » Cytochrome P450 2C9, structure 1 1og5 » Cytochrome P450 2C9, structure 1
7.6 ± 1.0 Å
spacer 1tqn » Cytochrome P450 3A4, conformation 1
8.7 ± 1.0 Å
1tqn » Cytochrome P450 3A4, conformation 1
lipid
lipid
  spacer   lipid
lipid
1z10 » Cytochrome P450 2A6 1z10 » Cytochrome P450 2A6
5.0 ± 1.7 Å
spacer 3o22 » Prostaglandin-H2 D-isomerase, ligand-bound
0.7 ± 1.2 Å
3o22 » Prostaglandin-H2 D-isomerase, ligand-bound
lipid
lipid
  spacer   lipid
lipid
2wx2 » Sterol 14-alpha-demethylase (CYP51), conformation 2 2wx2 » Sterol 14-alpha-demethylase (CYP51), conformation 2
5.9 ± 5.9 Å
spacer 2kb7 » Phospholamban, monomer
32.0 ± 2.2 Å
2kb7 » Phospholamban, monomer
lipid
lipid
  spacer   lipid
lipid
1rkl » Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4 (OST4) 1rkl » Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4 (OST4)
24.8 ± 3.2 Å
spacer 2lat » Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4 (OST4)
31.8 ± 3.5 Å
2lat » Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4 (OST4)
lipid
lipid
  spacer   lipid
lipid
3sja » ATPase Get3, complex with Get1 cytosolic domain 3sja » ATPase Get3, complex with Get1 cytosolic domain
6.4 ± 1.6 Å
spacer 4xry » Cytochrome P450 2D6, conformation 4
8.8 ± 3.0 Å
4xry » Cytochrome P450 2D6, conformation 4
lipid
lipid
  spacer   lipid
lipid
2yd0 » Endoplasmic reticulum aminopeptidase 1, different conformation 2yd0 » Endoplasmic reticulum aminopeptidase 1, different conformation
4.1 ± 2.2 Å
spacer 3mdj » Endoplasmic reticulum aminopeptidase 1
1.9 ± 3.6 Å
3mdj » Endoplasmic reticulum aminopeptidase 1
lipid
lipid
  spacer   lipid
lipid
1po5 » Cytochrome P450 2B4, open state 2 1po5 » Cytochrome P450 2B4, open state 2
3.5 ± 1.4 Å
spacer 1y5m » Corticosteroid 11-beta-dehydrogenase, isozyme 1
4.6 ± 0.4 Å
1y5m » Corticosteroid 11-beta-dehydrogenase, isozyme 1
lipid
lipid
  spacer   lipid
lipid
4qgk » Fatty aldehyde dehydrogenase 4qgk » Fatty aldehyde dehydrogenase
3.5 ± 1.9 Å
spacer 1xu7 » Corticosteroid 11-beta-dehydrogenase, isozyme 1
7.9 ± 0.2 Å
1xu7 » Corticosteroid 11-beta-dehydrogenase, isozyme 1
lipid
lipid
  spacer   lipid
lipid
3ar8 » Calcium ATPase, E2-Pi state, conformation 2 3ar8 » Calcium ATPase, E2-Pi state, conformation 2
28.6 ± 1.8 Å
spacer 3sn5 » Cholesterol 7-alpha-monooxygenase (P450 7A1), different conformation
6.0 ± 1.9 Å
3sn5 » Cholesterol 7-alpha-monooxygenase (P450 7A1), different conformation
lipid
lipid
  spacer   lipid
lipid
2ktd » Prostaglandin-H2 D-isomerase 2ktd » Prostaglandin-H2 D-isomerase
0.0 ± 1.4 Å
spacer 1nrj » Signal recognition particle receptor
3.9 ± 1.4 Å
1nrj » Signal recognition particle receptor
lipid
lipid
  spacer   lipid
lipid
2f9q » Cytochrome P450 2D6, conformation 1 2f9q » Cytochrome P450 2D6, conformation 1
7.0 ± 1.8 Å
spacer 2bdm » Cytochrome P450 2B4, open state 1
10.6 ± 1.0 Å
2bdm » Cytochrome P450 2B4, open state 1
lipid
lipid
  spacer   lipid
lipid
1r9o » Cytochrome P450 2C9, structure 2 1r9o » Cytochrome P450 2C9, structure 2
4.0 ± 1.1 Å
spacer 1dt6 » Cytochrome P450 2C5, different conformation
7.3 ± 1.0 Å
1dt6 » Cytochrome P450 2C5, different conformation
lipid
lipid
  spacer   lipid
lipid
2uuh » Leukotriene C4 synthase 2uuh » Leukotriene C4 synthase
29.4 ± 1.1 Å
spacer 3a36 » ATPase Get3, homodimer
5.6 ± 3.0 Å
3a36 » ATPase Get3, homodimer
lipid
lipid
  spacer   lipid
lipid
1r7g » Nonstructural protein 5a, segment 1973-2003 1r7g » Nonstructural protein 5a, segment 1973-2003
5.3 ± 0.9 Å
spacer 2ajo » Nonstructural protein 5a
5.0 ± 1.0 Å
2ajo » Nonstructural protein 5a
lipid
lipid
  spacer   lipid
lipid
1plp » Phospholamban, cytoplasmic helix 1plp » Phospholamban, cytoplasmic helix
4.0 ± 1.3 Å
spacer 2h8a » Microsomal glutathione S-transferase 1, structure 1
29.7 ± 0.7 Å
2h8a » Microsomal glutathione S-transferase 1, structure 1
lipid
lipid
  spacer   lipid
lipid
2q7r » FLAP protein (5-lipoxygenase activator) 2q7r » FLAP protein (5-lipoxygenase activator)
30.3 ± 1.3 Å
spacer 2hi4 » Cytochrome P450 1A2
6.9 ± 1.0 Å
2hi4 » Cytochrome P450 1A2
lipid
lipid
  spacer   lipid
lipid
3b6h » Prostacyclin synthase (cytochrome P450 8A1) 3b6h » Prostacyclin synthase (cytochrome P450 8A1)
5.0 ± 1.6 Å
spacer 3b9b » Calcium ATPase, E2-Pi state, conformation 3
29.9 ± 1.6 Å
3b9b » Calcium ATPase, E2-Pi state, conformation 3
lipid
lipid
  spacer   lipid
lipid
3e6i » Cytochrome P450 2E1 3e6i » Cytochrome P450 2E1
8.3 ± 2.0 Å
spacer 3czh » Cytochrome P450 2R1
8.3 ± 1.5 Å
3czh » Cytochrome P450 2R1
lipid
lipid
  spacer   lipid
lipid
2q9f » Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 1 2q9f » Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 1
2.8 ± 1.0 Å
spacer 3g49 » Corticosteroid 11-beta-dehydrogenase, isozyme 1
7.0 ± 0.5 Å
3g49 » Corticosteroid 11-beta-dehydrogenase, isozyme 1
lipid
lipid
  spacer   lipid
lipid
3dww » Microsomal prostaglandin E synthase 1, structure 1 3dww » Microsomal prostaglandin E synthase 1, structure 1
31.9 ± 1.1 Å
spacer 3eqm » Cytochrome P450 19A1 (estrogen synthetase)
6.1 ± 1.2 Å
3eqm » Cytochrome P450 19A1 (estrogen synthetase)
lipid
lipid
  spacer   lipid
lipid
3ld6 » Sterol 14-alpha-demethylase (CYP51) 3ld6 » Sterol 14-alpha-demethylase (CYP51)
8.9 ± 0.6 Å
spacer 3g1q » Sterol 14-alpha-demethylase (CYP51)
8.1 ± 1.5 Å
3g1q » Sterol 14-alpha-demethylase (CYP51)
lipid
lipid
  spacer   lipid
lipid
2wuz » Sterol 14-alpha-demethylase (CYP51), conformation 1 2wuz » Sterol 14-alpha-demethylase (CYP51), conformation 1
4.0 ± 1.1 Å
spacer 3l4d » Sterol 14-alpha-demethylase (CYP51)
8.4 ± 1.8 Å
3l4d » Sterol 14-alpha-demethylase (CYP51)
lipid
lipid
  spacer   lipid
lipid
2wwb » Protein translocase Sec61, complex with ribosome 2wwb » Protein translocase Sec61, complex with ribosome
26.3 ± 0.5 Å
spacer 3ar9 » Calcium ATPase, E2 state (Ca-free), conformation 7
29.0 ± 0.9 Å
3ar9 » Calcium ATPase, E2 state (Ca-free), conformation 7
lipid
lipid
  spacer   lipid
lipid
3mdm » Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 2 3mdm » Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 2
3.8 ± 1.3 Å
spacer 3nxu » Cytochrome P450 3A4, conformation 2
9.3 ± 1.0 Å
3nxu » Cytochrome P450 3A4, conformation 2
lipid
lipid
  spacer   lipid
lipid
1rp4 » Endoplasmic reticulum oxidoreductin 1rp4 » Endoplasmic reticulum oxidoreductin
2.0 ± 1.8 Å
spacer 3m31 » Endoplasmic reticulum oxidoreductin, a mutant
1.9 ± 1.2 Å
3m31 » Endoplasmic reticulum oxidoreductin, a mutant
lipid
lipid
  spacer   lipid
lipid
1fjk » Phospholamban, monomer 1fjk » Phospholamban, monomer
30.1 ± 3.2 Å
spacer 1n7l » Phospholamban, monomer
29.8 ± 3.6 Å
1n7l » Phospholamban, monomer
lipid
lipid
  spacer   lipid
lipid
3fo5 » Acyl-coenzyme A thioesterase 11 3fo5 » Acyl-coenzyme A thioesterase 11
2.3 ± 1.4 Å
spacer 3ibd » Cytochrome P450 2B6, conformation 1
4.7 ± 1.0 Å
3ibd » Cytochrome P450 2B6, conformation 1
lipid
lipid
  spacer   lipid
lipid
3dax » Cholesterol 7-alpha-monooxygenase (P450 7A1) 3dax » Cholesterol 7-alpha-monooxygenase (P450 7A1)
1.8 ± 1.9 Å
spacer 3pm0 » Cytochrome P450 1B1
3.8 ± 0.7 Å
3pm0 » Cytochrome P450 1B1
lipid
lipid
  spacer   lipid
lipid
2p85 » Cytochrome P450 2A13 2p85 » Cytochrome P450 2A13
4.9 ± 0.4 Å
spacer 3r1b » Cytochrome P450 2B4, open state 3
5.7 ± 0.0 Å
3r1b » Cytochrome P450 2B4, open state 3
lipid
lipid
  spacer   lipid
lipid
2kdr » Nonstructural protein 4b, segment 1938-1965 of polyprotein 2kdr » Nonstructural protein 4b, segment 1938-1965 of polyprotein
22.4 ± 2.0 Å
spacer 2jy0 » NS2 protease, segment 810-837 of polyprotein
23.8 ± 2.9 Å
2jy0 » NS2 protease, segment 810-837 of polyprotein
lipid
lipid
  spacer   lipid
lipid
2kwz » NS2 protease, segment 869-908 of polyprotein 2kwz » NS2 protease, segment 869-908 of polyprotein
29.8 ± 1.6 Å
spacer 2kwt » NS2 protease, segment 836-868 of polyprotein
9.5 ± 3.6 Å
2kwt » NS2 protease, segment 836-868 of polyprotein
lipid
lipid
  spacer   lipid
lipid
2jxf » Nonstructural protein 4b, segment 1751-1780 2jxf » Nonstructural protein 4b, segment 1751-1780
5.6 ± 3.6 Å
spacer 1qlo » ICP47 protein, active domain (1-34)
8.6 ± 0.8 Å
1qlo » ICP47 protein, active domain (1-34)
lipid
lipid
  spacer   lipid
lipid
2x43 » Small hydrophilic endoplasmic reticulum-associated protein (Sherp) 2x43 » Small hydrophilic endoplasmic reticulum-associated protein (Sherp)
4.1 ± 0.3 Å
spacer 3se6 » Endoplasmic reticulum aminopeptidase 2
2.5 ± 1.8 Å
3se6 » Endoplasmic reticulum aminopeptidase 2
lipid
lipid
  spacer   lipid
lipid
3swz » Cytochrome P450 17A1, structure 1 3swz » Cytochrome P450 17A1, structure 1
4.2 ± 1.6 Å
spacer 2wfm » Polyneuridine-aldehyde esterase
2.5 ± 1.7 Å
2wfm » Polyneuridine-aldehyde esterase
lipid
lipid
  spacer   lipid
lipid
5o5e » DPAGT1, dimer, structure 1 5o5e » DPAGT1, dimer, structure 1
31.0 ± 0.8 Å
spacer 3p8n » HCV serine protease NS3
8.7 ± 1.7 Å
3p8n » HCV serine protease NS3
lipid
lipid
  spacer   lipid
lipid
2o8m » Hepatitis C virus NS3 protease 2o8m » Hepatitis C virus NS3 protease
5.0 ± 1.3 Å
spacer 2whx » Serine protease/helicase NS3
4.4 ± 2.3 Å
2whx » Serine protease/helicase NS3
lipid
lipid
  spacer   lipid
lipid
2wv9 » Flavivirin protease NS2B 2wv9 » Flavivirin protease NS2B
1.6 ± 2.4 Å
spacer 2hd0 » Hepatitis C virus non-structural protein NS2 (955-1026)
6.7 ± 0.6 Å
2hd0 » Hepatitis C virus non-structural protein NS2 (955-1026)
lipid
lipid
  spacer   lipid
lipid
3fqm » Non-structural protein 5A 3fqm » Non-structural protein 5A
4.9 ± 1.1 Å
spacer 3qz1 » Steroid 21-hydroxylase (P450 C21)
5.9 ± 1.6 Å
3qz1 » Steroid 21-hydroxylase (P450 C21)
lipid
lipid
  spacer   lipid
lipid
1tpz » Interferon-inducible GTPase 1 1tpz » Interferon-inducible GTPase 1
2.5 ± 2.0 Å
spacer 2bcg » Secretory pathway GDP dissociation inhibitor
3.5 ± 1.0 Å
2bcg » Secretory pathway GDP dissociation inhibitor
lipid
lipid
  spacer   lipid
lipid
3ca7 » Protein spitz 3ca7 » Protein spitz
3.3 ± 2.8 Å
spacer 3qm4 » Cytochrome P450 2D6, conformation 3
9.0 ± 1.4 Å
3qm4 » Cytochrome P450 2D6, conformation 3
lipid
lipid
  spacer   lipid
lipid
3tgh » Glideosome-associated protein 50 3tgh » Glideosome-associated protein 50
4.2 ± 3.4 Å
spacer 3tlm » Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
26.8 ± 0.0 Å
3tlm » Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
lipid
lipid
  spacer   lipid
lipid
4aw6 » CAAX prenyl protease 1 homolog, structure 2 4aw6 » CAAX prenyl protease 1 homolog, structure 2
30.8 ± 1.3 Å
spacer 3tda » Cytochrome P450 2D6, conformation 2
8.0 ± 0.7 Å
3tda » Cytochrome P450 2D6, conformation 2
lipid
lipid
  spacer   lipid
lipid
3ua5 » Cytochrome P450 2B6, conformation 2 3ua5 » Cytochrome P450 2B6, conformation 2
4.7 ± 1.1 Å
spacer 2lm7 » Peptide of outer capsid glycoprotein VP7 (266-326)
10.2 ± 1.5 Å
2lm7 » Peptide of outer capsid glycoprotein VP7 (266-326)
lipid
lipid
  spacer   lipid
lipid
4bpm » Microsomal prostaglandin E synthase 1, structure 2 4bpm » Microsomal prostaglandin E synthase 1, structure 2
31.6 ± 1.4 Å
spacer 4il3 » CaaX Protease Ste24p
29.8 ± 1.4 Å
4il3 » CaaX Protease Ste24p
lipid
lipid
  spacer   lipid
lipid
4hhr » Alpha-dioxygenase 1 4hhr » Alpha-dioxygenase 1
10.8 ± 0.1 Å
spacer 4i8v » Cytochrome P450 1A1
7.1 ± 1.0 Å
4i8v » Cytochrome P450 1A1
lipid
lipid
  spacer   lipid
lipid
4fmm » Phosphatidylinositol transfer protein PDR16 4fmm » Phosphatidylinositol transfer protein PDR16
9.9 ± 2.6 Å
spacer 3w5a » Calcium ATPase, E1 Mg2+ state, complex with sarcolipin
26.8 ± 0.7 Å
3w5a » Calcium ATPase, E1 Mg2+ state, complex with  sarcolipin
lipid
lipid
  spacer   lipid
lipid
4h1w » Calcium ATPase, E1 Ca2+ state, complex with  sarcolipin 4h1w » Calcium ATPase, E1 Ca2+ state, complex with sarcolipin
27.6 ± 1.0 Å
spacer 2by4 » Calcium ATPase, E2 state (Ca-free), conformation 2
29.8 ± 1.3 Å
2by4 » Calcium ATPase, E2 state (Ca-free), conformation 2
lipid
lipid
  spacer   lipid
lipid
2ear » Calcium ATPase, E2 state (Ca-free), conformation 3 2ear » Calcium ATPase, E2 state (Ca-free), conformation 3
30.0 ± 1.2 Å
spacer 3fps » Calcium ATPase, E2 state (Ca-free), conformation 4
30.0 ± 0.9 Å
3fps » Calcium ATPase, E2 state (Ca-free), conformation 4
lipid
lipid
  spacer   lipid
lipid
1kju » Calcium ATPase, E2 state (Ca-free), conformation 5 1kju » Calcium ATPase, E2 state (Ca-free), conformation 5
33.8 ± 0.2 Å
spacer 2zbe » Calcium ATPase, E2 state (Ca-free), conformation 6
28.0 ± 0.7 Å
2zbe » Calcium ATPase, E2 state (Ca-free), conformation 6
lipid
lipid
  spacer   lipid
lipid
2zbg » Calcium ATPase, E2 state (Ca-free), conformation 8 2zbg » Calcium ATPase, E2 state (Ca-free), conformation 8
30.0 ± 1.7 Å
spacer 3b9r » Calcium ATPase, E2-Pi state, conformation 4
26.8 ± 0.0 Å
3b9r » Calcium ATPase, E2-Pi state, conformation 4
lipid
lipid
  spacer   lipid
lipid
3fpb » Calcium ATPase, E2-Pi state, conformation 5 3fpb » Calcium ATPase, E2-Pi state, conformation 5
27.0 ± 2.3 Å
spacer 1xp5 » Calcium ATPase, E2-Pi state, conformation 6
27.4 ± 1.1 Å
1xp5 » Calcium ATPase, E2-Pi state, conformation 6
lipid
lipid
  spacer   lipid
lipid
3n5k » Calcium ATPase, E2-Pi state, conformation 7 3n5k » Calcium ATPase, E2-Pi state, conformation 7
28.4 ± 1.3 Å
spacer 3ba6 » Calcium ATPase, E1-2Ca state, conformation 2
29.8 ± 0.7 Å
3ba6 » Calcium ATPase, E1-2Ca state, conformation 2
lipid
lipid
  spacer   lipid
lipid
1su4 » Calcium ATPase, E1-2Ca state, conformation 3 1su4 » Calcium ATPase, E1-2Ca state, conformation 3
30.0 ± 2.7 Å
spacer 2c9m » Calcium ATPase, E1-2Ca state, conformation 4
29.8 ± 1.2 Å
2c9m » Calcium ATPase, E1-2Ca state, conformation 4
lipid
lipid
  spacer   lipid
lipid
3ksw » Sterol 14-alpha-demethylase (CYP51), conformation 3 3ksw » Sterol 14-alpha-demethylase (CYP51), conformation 3
8.0 ± 6.7 Å
spacer 2q6n » Cytochrome P450 2B4, closed state 2
5.5 ± 0.4 Å
2q6n » Cytochrome P450 2B4, closed state 2
lipid
lipid
  spacer   lipid
lipid
3g5n » Cytochrome P450 2B4, closed state 3 3g5n » Cytochrome P450 2B4, closed state 3
5.7 ± 1.8 Å
spacer 2ko2 » Reticulon-4
2.5 ± 0.3 Å
2ko2 » Reticulon-4
lipid
lipid
  spacer   lipid
lipid
3v66 » Squalene synthase, conformation 1 3v66 » Squalene synthase, conformation 1
3.1 ± 0.8 Å
spacer 3wcf » Squalene synthase, conformation 2
2.8 ± 0.8 Å
3wcf » Squalene synthase, conformation 2
lipid
lipid
  spacer   lipid
lipid
4i91 » Cytochrome P450 2B6, conformation 3 4i91 » Cytochrome P450 2B6, conformation 3
4.7 ± 2.9 Å
spacer 4b2z » Oxysterol-binding protein homolog 6, conformation 1
1.3 ± 1.3 Å
4b2z » Oxysterol-binding protein homolog 6, conformation 1
lipid
lipid
  spacer   lipid
lipid
2m0s » Nonstructural protein 2a, segment 1194-1221 2m0s » Nonstructural protein 2a, segment 1194-1221
7.4 ± 3.6 Å
spacer 3b98 » Prostaglandin I2 synthase
4.4 ± 1.3 Å
3b98 » Prostaglandin I2 synthase
lipid
lipid
  spacer   lipid
lipid
4gqs » Cytochrome P450 2C19 4gqs » Cytochrome P450 2C19
6.4 ± 2.1 Å
spacer 4iap » PH domain of oxysterol-binding protein homolog 3, fused with lysozyme
2.5 ± 2.3 Å
4iap » PH domain of oxysterol-binding protein homolog 3, fused with lysozyme
lipid
lipid
  spacer   lipid
lipid
4ic4 » Oxysterol-binding protein homolog 3 4ic4 » Oxysterol-binding protein homolog 3
4.3 ± 0.9 Å
spacer 4kvl » Fatty acid alpha-oxidase
5.5 ± 0.7 Å
4kvl » Fatty acid alpha-oxidase
lipid
lipid
  spacer   lipid
lipid
4kyt » Calcium ATPase, E2 state (Ca-free), complex with phospholamban 4kyt » Calcium ATPase, E2 state (Ca-free), complex with phospholamban
28.0 ± 0.6 Å
spacer 3zd0 » P7 protein (747-809), structure 1
29.2 ± 4.2 Å
3zd0 » P7 protein (747-809), structure 1
lipid
lipid
  spacer   lipid
lipid
3zg2 » Sterol 14-alpha-demethylase (CYP51), conformation 4 3zg2 » Sterol 14-alpha-demethylase (CYP51), conformation 4
5.8 ± 1.0 Å
spacer 2m3b » Phospholamban, pentamer
32.0 ± 1.3 Å
2m3b » Phospholamban, pentamer
lipid
lipid
  spacer   lipid
lipid
4cad » Glutamate-dependent intramembrane protease Rce1 4cad » Glutamate-dependent intramembrane protease Rce1
30.8 ± 1.3 Å
spacer 4nab » Calcium ATPase, E1-2Ca state, conformation 5
28.8 ± 1.9 Å
4nab » Calcium ATPase, E1-2Ca state, conformation 5
lipid
lipid
  spacer   lipid
lipid
4j14 » Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 3 4j14 » Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 3
3.4 ± 1.4 Å
spacer 4wmz » Lanosterol 14-alpha demethylase (CYP51), with drug
29.8 ± 0.7 Å
4wmz » Lanosterol 14-alpha demethylase (CYP51), with drug
lipid
lipid
  spacer   lipid
lipid
4cg5 » Protein translocase Sec61, structure 1 4cg5 » Protein translocase Sec61, structure 1
27.2 ± 0.9 Å
spacer 4cg6 » Protein translocase Sec61, structure 2
28.8 ± 1.2 Å
4cg6 » Protein translocase Sec61, structure 2
lipid
lipid
  spacer   lipid
lipid
4cg7 » Protein translocase Sec61, structure 3 4cg7 » Protein translocase Sec61, structure 3
26.8 ± 0.3 Å
spacer 2m6x » P7 viral protein
26.8 ± 0.1 Å
2m6x » P7 viral protein
lipid
lipid
  spacer   lipid
lipid
4coh » Sterol 14-alpha-demethylase (CYP51), conformation 6 4coh » Sterol 14-alpha-demethylase (CYP51), conformation 6
6.3 ± 1.3 Å
spacer 4cml » Type II inositol 1,4,5-trisphosphate 5-phosphatase
4.6 ± 1.1 Å
4cml » Type II inositol 1,4,5-trisphosphate 5-phosphatase
lipid
lipid
  spacer   lipid
lipid
2lzq » NS2 protease, segment 766-789 of polyprotein 2lzq » NS2 protease, segment 766-789 of polyprotein
3.2 ± 2.1 Å
spacer 4bmm » Sterol 14-alpha-demethylase (CYP51), conformation 7
8.8 ± 3.3 Å
4bmm » Sterol 14-alpha-demethylase (CYP51), conformation 7
lipid
lipid
  spacer   lipid
lipid
3weh » Squalene synthase, conformation 3 3weh » Squalene synthase, conformation 3
1.4 ± 2.5 Å
spacer 3wek » Squalene synthase, conformation 4
0.4 ± 2.5 Å
3wek » Squalene synthase, conformation 4
lipid
lipid
  spacer   lipid
lipid
4ors » Prostaglandin-H2 D-isomerase, apo form 4ors » Prostaglandin-H2 D-isomerase, apo form
2.6 ± 0.8 Å
spacer 4os0 » Prostaglandin-H2 D-isomerase, apo form, mutant
2.4 ± 1.0 Å
4os0 » Prostaglandin-H2 D-isomerase, apo form, mutant
lipid
lipid
  spacer   lipid
lipid
4c0c » Sterol 14-alpha-demethylase (CYP51), conformation 8 4c0c » Sterol 14-alpha-demethylase (CYP51), conformation 8
9.4 ± 1.9 Å
spacer 5eqb » Lanosterol 14-alpha demethylase (CYP51), with lanosterol
29.8 ± 0.9 Å
5eqb » Lanosterol 14-alpha demethylase (CYP51), with lanosterol
lipid
lipid
  spacer   lipid
lipid
2mts » P7 protein (747-809), structure 2 2mts » P7 protein (747-809), structure 2
28.6 ± 2.1 Å
spacer 4w25 » Protein translocase Sec61, complex with ribosome
28.6 ± 1.1 Å
4w25 » Protein translocase Sec61, complex with ribosome
lipid
lipid
  spacer   lipid
lipid
4ntf » Leukotriene C4 synthase 4ntf » Leukotriene C4 synthase
29.8 ± 1.8 Å
spacer 4r1z » Cytochrome P450 17A1
5.0 ± 1.2 Å
4r1z » Cytochrome P450 17A1
lipid
lipid
  spacer   lipid
lipid
4ycl » Calcium ATPase, E2 state (Ca-free), conformation 9 4ycl » Calcium ATPase, E2 state (Ca-free), conformation 9
30.2 ± 1.6 Å
spacer 4y8w » Cytochrome P450 21-hydroxylase, 21A2
7.2 ± 0.7 Å
4y8w » Cytochrome P450 21-hydroxylase, 21A2
lipid
lipid
  spacer   lipid
lipid
4uis » Gamma-secretase complex, structure 2 4uis » Gamma-secretase complex, structure 2
36.8 ± 0.1 Å
spacer 4zyo » Acyl-CoA desaturase
29.2 ± 2.4 Å
4zyo » Acyl-CoA desaturase
lipid
lipid
  spacer   lipid
lipid
2ww9 » Protein translocase Sec61, complex with ribosome, active state 2ww9 » Protein translocase Sec61, complex with ribosome, active state
29.7 ± 1.7 Å
spacer 2wwa » Protein translocase Sec61, complex with ribosome, idle state
28.9 ± 1.6 Å
2wwa »  Protein translocase Sec61, complex with ribosome, idle state
lipid
lipid
  spacer   lipid
lipid
3kij » Glutathione peroxidase 8 3kij » Glutathione peroxidase 8
3.4 ± 2.7 Å
spacer 4zr1 » Ceramide fatty acid hydroxylase SCS7
28.2 ± 1.6 Å
4zr1 » Ceramide fatty acid hydroxylase SCS7
lipid
lipid
  spacer   lipid
lipid
4ph7 » Oxysterol-binding protein homolog 6, conformation 2 4ph7 » Oxysterol-binding protein homolog 6, conformation 2
2.5 ± 0.9 Å
spacer 5a63 » Gamma-secretase complex, structure 1
29.8 ± 0.6 Å
5a63 » Gamma-secretase complex, structure 1
lipid
lipid
  spacer   lipid
lipid
4ymk » Acyl-CoA desaturase 4ymk » Acyl-CoA desaturase
27.6 ± 2.1 Å
spacer 5a6u » Protein translocase Sec61, structure 4
29.8 ± 0.7 Å
5a6u » Protein translocase Sec61, structure 4
lipid
lipid
  spacer   lipid
lipid
5fn2 » Gamma-secretase complex, structure 3 5fn2 » Gamma-secretase complex, structure 3
31.4 ± 0.9 Å
spacer 5fn3 » Gamma-secretase complex, structure 4
30.6 ± 0.9 Å
5fn3 » Gamma-secretase complex, structure 4
lipid
lipid
  spacer   lipid
lipid
5fn4 » Gamma-secretase complex, structure 5 5fn4 » Gamma-secretase complex, structure 5
30.4 ± 0.9 Å
spacer 5fn5 » Gamma-secretase complex, structure 6
30.2 ± 1.2 Å
5fn5 » Gamma-secretase complex, structure 6
lipid
lipid
  spacer   lipid
lipid
4ycm » Calcium ATPase, E1 state, with macrolide BLS 4ycm » Calcium ATPase, E1 state, with macrolide BLS
3.2 ± 1.8 Å
spacer 3jc2 » Protein translocase Sec61, with signal peptide
28.8 ± 1.3 Å
3jc2 » Protein translocase Sec61, with signal peptide
lipid
lipid
  spacer   lipid
lipid
4zv8 » Cytochrome P450 2B6, conformation 4 4zv8 » Cytochrome P450 2B6, conformation 4
4.5 ± 1.7 Å
spacer 5f19 » Prostaglandin G/H synthase 2
6.2 ± 1.0 Å
5f19 » Prostaglandin G/H synthase 2
lipid
lipid
  spacer   lipid
lipid
2n7r » Nicastrin, TM helix 2n7r » Nicastrin, TM helix
31.4 ± 2.4 Å
spacer 5hk1 » Sigma intracellular receptor 1, structure 1
30.8 ± 0.6 Å
5hk1 » Sigma intracellular receptor 1, structure 1
lipid
lipid
  spacer   lipid
lipid
5hk2 » Sigma intracellular receptor 1, structure 2 5hk2 » Sigma intracellular receptor 1, structure 2
32.4 ± 1.4 Å
spacer 4zwn » Monoglyceride lipase
4.3 ± 1.7 Å
4zwn » Monoglyceride lipase
lipid
lipid
  spacer   lipid
lipid
5jlc » Lanosterol 14-alpha demethylase 5jlc » Lanosterol 14-alpha demethylase
29.8 ± 0.7 Å
spacer 5iut » Cytochrome P450 2B4, closed state, mutant
5.3 ± 0.5 Å
5iut » Cytochrome P450 2B4, closed state, mutant
lipid
lipid
  spacer   lipid
lipid
5gky » Ryanodine receptor 1, closed structure 1 5gky » Ryanodine receptor 1, closed structure 1
30.8 ± 0.0 Å
spacer 3j8h » Ryanodine receptor 1, closed structure 2
30.8 ± 0.0 Å
3j8h » Ryanodine receptor 1, closed structure 2
lipid
lipid
  spacer   lipid
lipid
5gkz » Ryanodine receptor 1, closed structure 3 5gkz » Ryanodine receptor 1, closed structure 3
30.8 ± 0.0 Å
spacer 5gl0 » Ryanodine receptor 1, various structures
30.8 ± 0.0 Å
5gl0 » Ryanodine receptor 1, various structures
lipid
lipid
  spacer   lipid
lipid
5gl1 » Ryanodine receptor 1, open structure 5gl1 » Ryanodine receptor 1, open structure
33.8 ± 0.0 Å
spacer 5eik » Trimeric intracellular cation channel, structure 1
26.8 ± 0.3 Å
5eik » Trimeric intracellular cation channel, structure 1
lipid
lipid
  spacer   lipid
lipid
5egi » Trimeric intracellular cation channel, structure 2 5egi » Trimeric intracellular cation channel, structure 2
30.8 ± 0.0 Å
spacer 5syt » CAAX prenyl protease 1 homolog, structure 1
31.4 ± 1.4 Å
5syt » CAAX prenyl protease 1 homolog, structure 1
lipid
lipid
  spacer   lipid
lipid
5lev » DPAGT1, monomer 5lev » DPAGT1, monomer
31.8 ± 1.0 Å
spacer 5u1d » Antigen peptide transporter 1 (TAP1)
30.6 ± 0.4 Å
5u1d » Antigen peptide transporter 1 (TAP1)
lipid
lipid
  spacer   lipid
lipid
5t6q » Cytochrome P450 4B1 5t6q » Cytochrome P450 4B1
8.8 ± 0.6 Å
spacer 5tz1 » Sterol 14-alpha-demethylase (CYP51), structure 1
8.7 ± 0.9 Å
5tz1 » Sterol 14-alpha-demethylase (CYP51), structure 1
lipid
lipid
  spacer   lipid
lipid
5fsa » Sterol 14-alpha-demethylase (CYP51), structure 2 5fsa » Sterol 14-alpha-demethylase (CYP51), structure 2
9.0 ± 0.8 Å
spacer 5te8 » Cytochrome P450 3A4, conformation 3
4.4 ± 1.6 Å
5te8 » Cytochrome P450 3A4, conformation 3
lipid
lipid
  spacer   lipid
lipid
5v5z » Sterol 14-alpha-demethylase (CYP51), structure 3 5v5z » Sterol 14-alpha-demethylase (CYP51), structure 3
30.8 ± 0.8 Å
spacer 5frb » Sterol 14-alpha-demethylase (CYP51)
11.8 ± 0.5 Å
5frb » Sterol 14-alpha-demethylase (CYP51)
lipid
lipid
  spacer   lipid
lipid
4r21 » Cytochrome P450 17A2 4r21 » Cytochrome P450 17A2
1.0 ± 10.0 Å
spacer 5xaa » Calcium ATPase, E2-Pi state, with lipids
30.6 ± 0.4 Å
5xaa » Calcium ATPase, E2-Pi state, with lipids
lipid
lipid
  spacer   lipid
lipid
5i9k » Microsomal glutathione S-transferase 1, structure 2 5i9k » Microsomal glutathione S-transferase 1, structure 2
25.8 ± 0.2 Å
spacer 5v6p » ERAD-associated E3 ubiquitin-protein ligase HRD1
30.2 ± 2.0 Å
5v6p » ERAD-associated E3 ubiquitin-protein ligase HRD1
lipid
lipid
  spacer   lipid
lipid
5w0c » Cytochrome P450 2C9, structure 3 5w0c » Cytochrome P450 2C9, structure 3
2.5 ± 3.0 Å
spacer 5v7v » ERAD-associated E3 ubiquitin-protein ligase component HRD3
8.3 ± 2.6 Å
5v7v » ERAD-associated E3 ubiquitin-protein ligase component HRD3
lipid
lipid
  spacer   lipid
lipid
5tl8 » Sterol 14-alpha-demethylase (CYP51) 5tl8 » Sterol 14-alpha-demethylase (CYP51)
6.2 ± 1.2 Å
spacer 5x23 » Cytochrome P450 2C9, structure 4
6.9 ± 0.8 Å
5x23 » Cytochrome P450 2C9, structure 4
lipid
lipid
  spacer   lipid
lipid
5veu » Cytochrome P450 3A4 5veu » Cytochrome P450 3A4
4.7 ± 1.2 Å
spacer 6bdh » Cytochrome P450 3A4, conformation 4
5.9 ± 0.6 Å
6bdh » Cytochrome P450 3A4, conformation 4
lipid
lipid
  spacer   lipid
lipid
6b82 » Cytochrome P450 17A1 6b82 » Cytochrome P450 17A1
6.3 ± 1.6 Å
spacer 5kiu » Selenoprotein S
2.3 ± 4.2 Å
5kiu » Selenoprotein S
lipid
lipid
  spacer   lipid
lipid
5ncq » Calcium ATPase, E2 state (Ca-free), conformation 10 5ncq » Calcium ATPase, E2 state (Ca-free), conformation 10
30.2 ± 1.2 Å
spacer 6bym » Second StART domain of Lam4
3.0 ± 0.8 Å
6bym » Second StART domain of Lam4
lipid
lipid
  spacer   lipid
lipid
6ezn » Oligosaccharyltransferase complex, structure 1 6ezn » Oligosaccharyltransferase complex, structure 1
30.2 ± 0.6 Å
spacer 5mpm » Calcium ATPase, E1-2Ca state
31.0 ± 0.6 Å
5mpm » Calcium ATPase, E1-2Ca state
lipid
lipid
  spacer   lipid
lipid
5v7p » RAS methyltransferase ICMT 5v7p » RAS methyltransferase ICMT
29.8 ± 1.2 Å
spacer 6c26 » Oligosaccharyltransferase complex, structure 2
30.6 ± 0.6 Å
6c26 » Oligosaccharyltransferase complex, structure 2
lipid
lipid
  spacer   lipid
lipid
5yqi » First StARkin domain of Lam2 5yqi » First StARkin domain of Lam2
1.9 ± 1.6 Å
spacer 5ys0 » Second StARkin domain of Lam2
4.4 ± 1.6 Å
5ys0 » Second StARkin domain of Lam2
lipid
lipid
  spacer   lipid
lipid
5yqq » Second StARkin domain of Lam2, dimer 5yqq » Second StARkin domain of Lam2, dimer
5.8 ± 1.6 Å
spacer 5yqj » First StARkin domain of Lam4
9.3 ± 1.4 Å
5yqj » First StARkin domain of Lam4
lipid
lipid
  spacer   lipid
lipid
5yqr » PH-like domain of Lam6 5yqr » PH-like domain of Lam6
1.6 ± 1.6 Å
spacer 6bw6 » DPAGT1, dimer, structure 2
31.0 ± 1.2 Å
6bw6 » DPAGT1, dimer, structure 2
lipid
lipid
  spacer   lipid
lipid
5uys » Cytochrome P450 17A1, structure 2 5uys » Cytochrome P450 17A1, structure 2
4.5 ± 0.4 Å
spacer 6ftj » Ribosome-translocon-oligosaccharyltransferase complex, structure 1
30.2 ± 2.0 Å
6ftj » Ribosome-translocon-oligosaccharyltransferase complex, structure 1
lipid
lipid
  spacer   lipid
lipid
6ftg » Ribosome-translocon-oligosaccharyltransferase complex, structure 2 6ftg » Ribosome-translocon-oligosaccharyltransferase complex, structure 2
26.6 ± 0.0 Å
spacer 2k8j » P7 protein (781-809)
23.6 ± 5.4 Å
2k8j » P7 protein (781-809)
corner Endoplasmic reticulum membrane corner
Membrane Lipid Composition
Nat Rev Mol Cell Biol. 2008 Feb;9(2):112-24. Membrane lipids: where they are and how they behave.