PDB ID or protein name

Membrane Protein Lipid Composition Atlas

1. Archaebacterial membrane (72 proteins)
2. Bacterial Gram-negative inner membrane (321 proteins)
3. Bacterial Gram-negative outer membrane (164 proteins)
4. Bacterial Gram-positive outer membrane (7 proteins)
5. Bacterial Gram-positive plasma membrane (107 proteins)
6. Chloroplast inner membrane (1 protein)
7. Chloroplast outer membrane (0 proteins)
8. Cytoplasmic granule membrane (1 protein)
9. Endoplasmic reticulum membrane (152 proteins)
10. Endosome membrane (39 proteins)
11. Eukaryotic plasma membrane (567 proteins)
12. Golgi membrane (26 proteins)
13. Lysosome membrane (17 proteins)
14. Mitochondrial inner membrane (56 proteins)
15. Mitochondrial outer membrane (24 proteins)
16. Nuclear inner membrane (3 proteins)
17. Nuclear outer membrane (6 proteins)
18. Peroxisome membrane (11 proteins)
19. Secreted (723 proteins)
20. Thylakoid membrane (33 proteins)
21. Undefined (77 proteins)
22. Vacuole membrane (18 proteins)
23. Vesicle membrane (14 proteins)
24. Viral membrane (43 proteins)

Lipid Composition in Endoplasmic reticulum membrane

Cell/Species PC % PE % PI % PS % PA % CL % Sph % Ch % CB % SL % PI+PS % PI+LPE % LPC % PG %
Rat Liver (male Wistar)
Rattus norvegicus
53.0 20.2 - - - - 3.7 - - - 14.1 - - -
Barley Roots
Hordeum vulgare
58.0 20.9 - 1.4 1.0 - - - - - - 2.2 6.4
Light Microsomes
Saccharomyces cerevisiae
51.3 33.4 7.5 6.6 0.2 0.4 - - - - - - - -

Endoplasmic reticulum membrane

corner lipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipid corner
lipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipid
2jo1 » Na,K-ATPase regulatory protein FXYD1 (phospholemman) 2jo1 » Na,K-ATPase regulatory protein FXYD1 (phospholemman)
30.6 ± 2.5 Å
spacer 3ar2 » Calcium ATPase, E1-2Ca state, conformation 1
29.6 ± 0.9 Å
3ar2 » Calcium ATPase, E1-2Ca state, conformation 1
lipid
lipid
  spacer   lipid
lipid
1wpg » Calcium ATPase, E2-Pi state, conformation 1 1wpg » Calcium ATPase, E2-Pi state, conformation 1
30.6 ± 1.1 Å
spacer 1t5s » Calcium ATPase, E1-ATP state
29.7 ± 1.6 Å
1t5s » Calcium ATPase, E1-ATP state
lipid
lipid
  spacer   lipid
lipid
2zbd » Calcium ATPase, E1P-ADP state 2zbd » Calcium ATPase, E1P-ADP state
31.8 ± 1.4 Å
spacer 1p49 » Steryl-sulfatase
29.6 ± 1.1 Å
1p49 » Steryl-sulfatase
lipid
lipid
  spacer   lipid
lipid
1mt5 » Fatty acid amide hydrolase 1mt5 » Fatty acid amide hydrolase
11.1 ± 0.2 Å
spacer 1cx2 » Prostaglandin H2 synthase-2 (cyclooxygenase)
9.7 ± 0.4 Å
1cx2 » Prostaglandin H2 synthase-2 (cyclooxygenase)
lipid
lipid
  spacer   lipid
lipid
1zll » Phospholamban, pentamer 1zll » Phospholamban, pentamer
30.5 ± 1.4 Å
spacer 2agv » Calcium ATPase, E2 state (Ca-free), conformation 1
29.7 ± 2.2 Å
2agv » Calcium ATPase, E2 state (Ca-free), conformation 1
lipid
lipid
  spacer   lipid
lipid
1jdm » Sarcolipin 1jdm » Sarcolipin
29.6 ± 2.4 Å
spacer 1q4g » Prostaglandin H2 synthase-1
8.9 ± 0.4 Å
1q4g » Prostaglandin H2 synthase-1
lipid
lipid
  spacer   lipid
lipid
1w6k » Lanosterol synthase 1w6k » Lanosterol synthase
7.6 ± 1.0 Å
spacer 1nr6 » Cytochrome P450 2C5
10.6 ± 1.0 Å
1nr6 » Cytochrome P450 2C5
lipid
lipid
  spacer   lipid
lipid
1suo » Cytochrome P450 2B4, closed state 1 1suo » Cytochrome P450 2B4, closed state 1
4.6 ± 1.3 Å
spacer 1pq2 » Cytochrome P450 2C8
3.8 ± 1.8 Å
1pq2 » Cytochrome P450 2C8
lipid
lipid
  spacer   lipid
lipid
1og5 » Cytochrome P450 2C9 1og5 » Cytochrome P450 2C9
7.6 ± 1.0 Å
spacer 1tqn » Cytochrome P450 3A4, conformation 1
8.7 ± 1.0 Å
1tqn » Cytochrome P450 3A4, conformation 1
lipid
lipid
  spacer   lipid
lipid
1z10 » Cytochrome P450 2A6 1z10 » Cytochrome P450 2A6
5.0 ± 1.7 Å
spacer 3o22 » Prostaglandin-H2 D-isomerase
0.7 ± 1.2 Å
3o22 » Prostaglandin-H2 D-isomerase
lipid
lipid
  spacer   lipid
lipid
2wx2 » Sterol 14-alpha-demethylase (CYP51), conformation 2 2wx2 » Sterol 14-alpha-demethylase (CYP51), conformation 2
5.9 ± 5.9 Å
spacer 2kb7 » Phospholamban, monomer
32.0 ± 2.2 Å
2kb7 » Phospholamban, monomer
lipid
lipid
  spacer   lipid
lipid
1rkl » Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4 (OST4) 1rkl » Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4 (OST4)
24.8 ± 3.2 Å
spacer 2lat » Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4 (OST4)
31.8 ± 3.5 Å
2lat » Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4 (OST4)
lipid
lipid
  spacer   lipid
lipid
3sja » ATPase Get3, complex with Get1 cytosolic domain 3sja » ATPase Get3, complex with Get1 cytosolic domain
6.4 ± 1.6 Å
spacer 2yd0 » Endoplasmic reticulum aminopeptidase 1, different conformation
4.1 ± 2.2 Å
2yd0 » Endoplasmic reticulum aminopeptidase 1, different conformation
lipid
lipid
  spacer   lipid
lipid
3mdj » Endoplasmic reticulum aminopeptidase 1 3mdj » Endoplasmic reticulum aminopeptidase 1
1.9 ± 3.6 Å
spacer 1po5 » Cytochrome P450 2B4, open state 2
3.5 ± 1.4 Å
1po5 » Cytochrome P450 2B4, open state 2
lipid
lipid
  spacer   lipid
lipid
1y5m » Corticosteroid 11-beta-dehydrogenase, isozyme 1 1y5m » Corticosteroid 11-beta-dehydrogenase, isozyme 1
4.6 ± 0.4 Å
spacer 1xu7 » Corticosteroid 11-beta-dehydrogenase, isozyme 1
7.9 ± 0.2 Å
1xu7 » Corticosteroid 11-beta-dehydrogenase, isozyme 1
lipid
lipid
  spacer   lipid
lipid
3ar8 » Calcium ATPase, E2-Pi state, conformation 2 3ar8 » Calcium ATPase, E2-Pi state, conformation 2
28.6 ± 1.8 Å
spacer 3sn5 » Cholesterol 7-alpha-monooxygenase (P450 7A1), different conformation
6.0 ± 1.9 Å
3sn5 » Cholesterol 7-alpha-monooxygenase (P450 7A1), different conformation
lipid
lipid
  spacer   lipid
lipid
2ktd » Prostaglandin-H2 D-isomerase 2ktd » Prostaglandin-H2 D-isomerase
0.0 ± 1.4 Å
spacer 1nrj » Signal recognition particle receptor
3.9 ± 1.4 Å
1nrj » Signal recognition particle receptor
lipid
lipid
  spacer   lipid
lipid
2f9q » Cytochrome P450 2D6, conformation 1 2f9q » Cytochrome P450 2D6, conformation 1
7.0 ± 1.8 Å
spacer 2bdm » Cytochrome P450 2B4, open state 1
10.6 ± 1.0 Å
2bdm » Cytochrome P450 2B4, open state 1
lipid
lipid
  spacer   lipid
lipid
1r9o » Cytochrome P450 2C9, different conformation 1r9o » Cytochrome P450 2C9, different conformation
4.0 ± 1.1 Å
spacer 1dt6 » Cytochrome P450 2C5, different conformation
7.3 ± 1.0 Å
1dt6 » Cytochrome P450 2C5, different conformation
lipid
lipid
  spacer   lipid
lipid
2uuh » Leukotriene C4 synthase 2uuh » Leukotriene C4 synthase
29.4 ± 1.1 Å
spacer 3a36 » ATPase Get3, homodimer
5.6 ± 3.0 Å
3a36 » ATPase Get3, homodimer
lipid
lipid
  spacer   lipid
lipid
1r7g » Nonstructural protein 5a, segment 1973-2003 of polyprotein 1r7g » Nonstructural protein 5a, segment 1973-2003 of polyprotein
5.3 ± 0.9 Å
spacer 2ajo » Nonstructural protein 5a
5.0 ± 1.0 Å
2ajo » Nonstructural protein 5a
lipid
lipid
  spacer   lipid
lipid
1plp » Phospholamban, cytoplasmic helix 1plp » Phospholamban, cytoplasmic helix
4.0 ± 1.3 Å
spacer 2h8a » Microsomal glutathione S-transferase 1
29.7 ± 0.7 Å
2h8a » Microsomal glutathione S-transferase 1
lipid
lipid
  spacer   lipid
lipid
2q7r » FLAP protein (5-lipoxygenase activator) 2q7r » FLAP protein (5-lipoxygenase activator)
30.3 ± 1.3 Å
spacer 2hi4 » Cytochrome P450 1A2
6.9 ± 1.0 Å
2hi4 » Cytochrome P450 1A2
lipid
lipid
  spacer   lipid
lipid
3b6h » Prostacyclin synthase (cytochrome P450 8A1) 3b6h » Prostacyclin synthase (cytochrome P450 8A1)
5.0 ± 1.6 Å
spacer 3b9b » Calcium ATPase, E2-Pi state, conformation 3
29.9 ± 1.6 Å
3b9b » Calcium ATPase, E2-Pi state, conformation 3
lipid
lipid
  spacer   lipid
lipid
3e6i » Cytochrome P450 2E1 3e6i » Cytochrome P450 2E1
8.3 ± 2.0 Å
spacer 3czh » Cytochrome P450 2R1
8.3 ± 1.5 Å
3czh » Cytochrome P450 2R1
lipid
lipid
  spacer   lipid
lipid
2q9f » Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 1 2q9f » Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 1
2.8 ± 1.0 Å
spacer 3g49 » Corticosteroid 11-beta-dehydrogenase, isozyme 1
7.0 ± 0.5 Å
3g49 » Corticosteroid 11-beta-dehydrogenase, isozyme 1
lipid
lipid
  spacer   lipid
lipid
3dww » Microsomal prostaglandin E synthase 1, conformation 1 3dww » Microsomal prostaglandin E synthase 1, conformation 1
31.9 ± 1.1 Å
spacer 3eqm » Cytochrome P450 19A1 (aromatase, estrogen synthetase)
6.1 ± 1.2 Å
3eqm » Cytochrome P450 19A1 (aromatase, estrogen synthetase)
lipid
lipid
  spacer   lipid
lipid
3ld6 » Sterol 14-alpha-demethylase (CYP51) 3ld6 » Sterol 14-alpha-demethylase (CYP51)
8.9 ± 0.6 Å
spacer 2jp3 » Na,K-ATPase regulatory protein FXYD4
31.8 ± 3.2 Å
2jp3 » Na,K-ATPase regulatory protein FXYD4
lipid
lipid
  spacer   lipid
lipid
3g1q » Sterol 14-alpha-demethylase (CYP51) 3g1q » Sterol 14-alpha-demethylase (CYP51)
8.1 ± 1.5 Å
spacer 2wuz » Sterol 14-alpha-demethylase (CYP51), conformation 1
4.0 ± 1.1 Å
2wuz » Sterol 14-alpha-demethylase (CYP51), conformation 1
lipid
lipid
  spacer   lipid
lipid
3l4d » Sterol 14-alpha-demethylase (CYP51) 3l4d » Sterol 14-alpha-demethylase (CYP51)
8.4 ± 1.8 Å
spacer 2wwb » Protein translocase Sec61, complex with ribosome
26.3 ± 0.5 Å
2wwb » Protein translocase Sec61, complex with ribosome
lipid
lipid
  spacer   lipid
lipid
3ar9 » Calcium ATPase, E2 state, Ca-free, conformation 7 3ar9 » Calcium ATPase, E2 state, Ca-free, conformation 7
29.0 ± 0.9 Å
spacer 3mdm » Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 2
3.8 ± 1.3 Å
3mdm » Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 2
lipid
lipid
  spacer   lipid
lipid
3nxu » Cytochrome P450 3A4, conformation 2 3nxu » Cytochrome P450 3A4, conformation 2
9.3 ± 1.0 Å
spacer 1rp4 » Endoplasmic reticulum oxidoreductin
2.0 ± 1.8 Å
1rp4 » Endoplasmic reticulum oxidoreductin
lipid
lipid
  spacer   lipid
lipid
3m31 » Endoplasmic reticulum oxidoreductin, a mutant 3m31 » Endoplasmic reticulum oxidoreductin, a mutant
1.9 ± 1.2 Å
spacer 1fjk » Phospholamban, monomer
30.1 ± 3.2 Å
1fjk » Phospholamban, monomer
lipid
lipid
  spacer   lipid
lipid
1n7l » Phospholamban, monomer 1n7l » Phospholamban, monomer
29.8 ± 3.6 Å
spacer 3fo5 » Acyl-coenzyme A thioesterase 11
2.3 ± 1.4 Å
3fo5 » Acyl-coenzyme A thioesterase 11
lipid
lipid
  spacer   lipid
lipid
3ibd » Cytochrome P450 2B6, conformation 1 3ibd » Cytochrome P450 2B6, conformation 1
4.7 ± 1.0 Å
spacer 3dax » Cholesterol 7-alpha-monooxygenase (P450 7A1)
1.8 ± 1.9 Å
3dax » Cholesterol 7-alpha-monooxygenase (P450 7A1)
lipid
lipid
  spacer   lipid
lipid
3pm0 » Cytochrome P450 1B1 3pm0 » Cytochrome P450 1B1
3.8 ± 0.7 Å
spacer 2p85 » Cytochrome P450 2A13
4.9 ± 0.4 Å
2p85 » Cytochrome P450 2A13
lipid
lipid
  spacer   lipid
lipid
3r1b » Cytochrome P450 2B4, open state 3 3r1b » Cytochrome P450 2B4, open state 3
5.7 ± 0.0 Å
spacer 2kdr » Nonstructural protein 4b, segment 1938-1965 of polyprotein
22.4 ± 2.0 Å
2kdr » Nonstructural protein 4b, segment 1938-1965 of polyprotein
lipid
lipid
  spacer   lipid
lipid
2jy0 » NS2 protease, segment 810-837 of polyprotein 2jy0 » NS2 protease, segment 810-837 of polyprotein
23.8 ± 2.9 Å
spacer 2kwz » NS2 protease, segment 869-908 of polyprotein
29.8 ± 1.6 Å
2kwz » NS2 protease, segment 869-908 of polyprotein
lipid
lipid
  spacer   lipid
lipid
2kwt » NS2 protease, segment 836-868 of polyprotein 2kwt » NS2 protease, segment 836-868 of polyprotein
9.5 ± 3.6 Å
spacer 2jxf » Nonstructural protein 4b, segment 1751-1780
5.6 ± 3.6 Å
2jxf » Nonstructural protein 4b, segment 1751-1780
lipid
lipid
  spacer   lipid
lipid
1qlo » ICP47 protein, active domain (1-34) 1qlo » ICP47 protein, active domain (1-34)
8.6 ± 0.8 Å
spacer 2x43 » Small hydrophilic endoplasmic reticulum-associated protein (Sherp)
4.1 ± 0.3 Å
2x43 » Small hydrophilic endoplasmic reticulum-associated protein (Sherp)
lipid
lipid
  spacer   lipid
lipid
3se6 » Endoplasmic reticulum aminopeptidase 2 3se6 » Endoplasmic reticulum aminopeptidase 2
2.5 ± 1.8 Å
spacer 3swz » Steroid 17-alpha-hydroxylase/17,20 lyase (P450 17A1)
4.2 ± 1.6 Å
3swz » Steroid 17-alpha-hydroxylase/17,20 lyase (P450 17A1)
lipid
lipid
  spacer   lipid
lipid
2wfm » Polyneuridine-aldehyde esterase 2wfm » Polyneuridine-aldehyde esterase
2.5 ± 1.7 Å
spacer 3p8n » HCV serine protease NS3
8.7 ± 1.7 Å
3p8n » HCV serine protease NS3
lipid
lipid
  spacer   lipid
lipid
2o8m » Hepatitis C virus NS3 protease 2o8m » Hepatitis C virus NS3 protease
5.0 ± 1.3 Å
spacer 2whx » Serine protease/helicase NS3
4.4 ± 2.3 Å
2whx » Serine protease/helicase NS3
lipid
lipid
  spacer   lipid
lipid
2wv9 » Flavivirin protease NS2B 2wv9 » Flavivirin protease NS2B
1.6 ± 2.4 Å
spacer 2hd0 » Hepatitis C virus non-structural protein NS2
6.7 ± 0.6 Å
2hd0 » Hepatitis C virus non-structural protein NS2
lipid
lipid
  spacer   lipid
lipid
3fqm » Non-structural protein 5A 3fqm » Non-structural protein 5A
4.9 ± 1.1 Å
spacer 3qz1 » Steroid 21-hydroxylase (P450 C21)
5.9 ± 1.6 Å
3qz1 » Steroid 21-hydroxylase (P450 C21)
lipid
lipid
  spacer   lipid
lipid
1tpz » Interferon-inducible GTPase 1 1tpz » Interferon-inducible GTPase 1
2.5 ± 2.0 Å
spacer 2bcg » Secretory pathway GDP dissociation inhibitor
3.5 ± 1.0 Å
2bcg » Secretory pathway GDP dissociation inhibitor
lipid
lipid
  spacer   lipid
lipid
3ca7 » Protein spitz 3ca7 » Protein spitz
3.3 ± 2.8 Å
spacer 3qm4 » Cytochrome P450 2D6, conformation 3
9.0 ± 1.4 Å
3qm4 » Cytochrome P450 2D6, conformation 3
lipid
lipid
  spacer   lipid
lipid
3tgh » Glideosome-associated protein 50 3tgh » Glideosome-associated protein 50
4.2 ± 3.4 Å
spacer 3tlm » Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
26.8 ± 0.0 Å
3tlm » Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
lipid
lipid
  spacer   lipid
lipid
4aw6 » CAAX prenyl protease 1 homolog 4aw6 » CAAX prenyl protease 1 homolog
30.8 ± 1.3 Å
spacer 3tda » Cytochrome P450 2D6, conformation 2
8.0 ± 0.7 Å
3tda » Cytochrome P450 2D6, conformation 2
lipid
lipid
  spacer   lipid
lipid
3ua5 » Cytochrome P450 2B6, conformation 2 3ua5 » Cytochrome P450 2B6, conformation 2
4.7 ± 1.1 Å
spacer 2lm7 » Peptide of outer capsid glycoprotein VP7 (266-326)
10.2 ± 1.5 Å
2lm7 » Peptide of outer capsid glycoprotein VP7 (266-326)
lipid
lipid
  spacer   lipid
lipid
4bpm » Microsomal prostaglandin E synthase 1, conformation 2 4bpm » Microsomal prostaglandin E synthase 1, conformation 2
31.6 ± 1.4 Å
spacer 4il3 » CaaX Protease Ste24p
29.8 ± 1.4 Å
4il3 » CaaX Protease Ste24p
lipid
lipid
  spacer   lipid
lipid
4hhr » Alpha-dioxygenase 1 4hhr » Alpha-dioxygenase 1
10.8 ± 0.1 Å
spacer 4i8v » Cytochrome P450 1A1
7.1 ± 1.0 Å
4i8v » Cytochrome P450 1A1
lipid
lipid
  spacer   lipid
lipid
4fmm » Phosphatidylinositol transfer protein PDR16 4fmm » Phosphatidylinositol transfer protein PDR16
9.9 ± 2.6 Å
spacer 3w5a » Calcium ATPase, E1 Mg2+ state, complex with sarcolipin
26.8 ± 0.7 Å
3w5a » Calcium ATPase, E1 Mg2+ state, complex with  sarcolipin
lipid
lipid
  spacer   lipid
lipid
4h1w » Calcium ATPase, E1 Ca2+ state, complex with  sarcolipin 4h1w » Calcium ATPase, E1 Ca2+ state, complex with sarcolipin
27.6 ± 1.0 Å
spacer 2by4 » Calcium ATPase, E2 state (Ca-free), conformation 2
29.8 ± 1.3 Å
2by4 » Calcium ATPase, E2 state (Ca-free), conformation 2
lipid
lipid
  spacer   lipid
lipid
2ear » Calcium ATPase, E2 state, Ca-free, conformation 3 2ear » Calcium ATPase, E2 state, Ca-free, conformation 3
30.0 ± 1.2 Å
spacer 3fps » Calcium ATPase, E2 state (Ca-free), conformation 4
30.0 ± 0.9 Å
3fps » Calcium ATPase, E2 state (Ca-free), conformation 4
lipid
lipid
  spacer   lipid
lipid
1kju » Calcium ATPase, E2 state (Ca-free), conformation 5 1kju » Calcium ATPase, E2 state (Ca-free), conformation 5
33.8 ± 0.2 Å
spacer 2zbe » Calcium ATPase, E2 state (Ca-free), conformation 6
28.0 ± 0.7 Å
2zbe » Calcium ATPase, E2 state (Ca-free), conformation 6
lipid
lipid
  spacer   lipid
lipid
2zbg » Calcium ATPase, E2 state (Ca-free), conformation 8 2zbg » Calcium ATPase, E2 state (Ca-free), conformation 8
30.0 ± 1.7 Å
spacer 3b9r » Calcium ATPase, E2-Pi state, conformation 4
26.8 ± 0.0 Å
3b9r » Calcium ATPase, E2-Pi state, conformation 4
lipid
lipid
  spacer   lipid
lipid
3fpb » Calcium ATPase, E2-Pi state, conformation 5 3fpb » Calcium ATPase, E2-Pi state, conformation 5
27.0 ± 2.3 Å
spacer 1xp5 » Calcium ATPase, E2-Pi state, conformation 6
27.4 ± 1.1 Å
1xp5 » Calcium ATPase, E2-Pi state, conformation 6
lipid
lipid
  spacer   lipid
lipid
3n5k » Calcium ATPase, E2-Pi state, conformation 7 3n5k » Calcium ATPase, E2-Pi state, conformation 7
28.4 ± 1.3 Å
spacer 3ba6 » Calcium ATPase, E1-2Ca state, conformation 2
29.8 ± 0.7 Å
3ba6 » Calcium ATPase, E1-2Ca state, conformation 2
lipid
lipid
  spacer   lipid
lipid
1su4 » Calcium ATPase, E1-2Ca state, conformation 3 1su4 » Calcium ATPase, E1-2Ca state, conformation 3
30.0 ± 2.7 Å
spacer 2c9m » Calcium ATPase, E1-2Ca state, conformation 4
29.8 ± 1.2 Å
2c9m » Calcium ATPase, E1-2Ca state, conformation 4
lipid
lipid
  spacer   lipid
lipid
3ksw » Sterol 14-alpha-demethylase (CYP51), conformation 3 3ksw » Sterol 14-alpha-demethylase (CYP51), conformation 3
8.0 ± 6.7 Å
spacer 2q6n » Cytochrome P450 2B4, closed state 2
5.5 ± 0.4 Å
2q6n » Cytochrome P450 2B4, closed state 2
lipid
lipid
  spacer   lipid
lipid
3g5n » Cytochrome P450 2B4, closed state 3 3g5n » Cytochrome P450 2B4, closed state 3
5.7 ± 1.8 Å
spacer 2ko2 » Reticulon-4
2.5 ± 0.3 Å
2ko2 » Reticulon-4
lipid
lipid
  spacer   lipid
lipid
3v66 » Squalene synthase, conformation 1 3v66 » Squalene synthase, conformation 1
3.1 ± 0.8 Å
spacer 3wcf » Squalene synthase, conformation 2
2.8 ± 0.8 Å
3wcf » Squalene synthase, conformation 2
lipid
lipid
  spacer   lipid
lipid
4i91 » Cytochrome P450 2B6, conformation 3 4i91 » Cytochrome P450 2B6, conformation 3
4.7 ± 2.9 Å
spacer 4b2z » Oxysterol-binding protein homolog 6
1.3 ± 1.3 Å
4b2z » Oxysterol-binding protein homolog 6
lipid
lipid
  spacer   lipid
lipid
2m0s » Nonstructural protein 2a, segment 1194-1221 2m0s » Nonstructural protein 2a, segment 1194-1221
7.4 ± 3.6 Å
spacer 3b98 » Prostaglandin I2 synthase
4.4 ± 1.3 Å
3b98 » Prostaglandin I2 synthase
lipid
lipid
  spacer   lipid
lipid
4iap » PH domain of oxysterol-binding protein homolog 3, fused with lysozyme 4iap » PH domain of oxysterol-binding protein homolog 3, fused with lysozyme
2.5 ± 2.3 Å
spacer 4ic4 » Oxysterol-binding protein homolog 3
4.3 ± 0.9 Å
4ic4 » Oxysterol-binding protein homolog 3
lipid
lipid
  spacer   lipid
lipid
4kvl » Fatty acid alpha-oxidase 4kvl » Fatty acid alpha-oxidase
5.5 ± 0.7 Å
spacer 4kyt » Calcium ATPase, E2 state (Ca-free), complex with phospholamban
28.0 ± 0.6 Å
4kyt » Calcium ATPase, E2 state (Ca-free), complex with phospholamban
lipid
lipid
  spacer   lipid
lipid
3zd0 » Hepatitis C P7 protein 3zd0 » Hepatitis C P7 protein
29.2 ± 4.2 Å
spacer 3zg2 » Sterol 14-alpha-demethylase (CYP51), conformation 4
5.8 ± 1.0 Å
3zg2 » Sterol 14-alpha-demethylase (CYP51), conformation 4
lipid
lipid
  spacer   lipid
lipid
2m3b » Phospholamban, pentamer 2m3b » Phospholamban, pentamer
32.0 ± 1.3 Å
spacer 4cad » Glutamate-dependent intramembrane protease Rce1
30.8 ± 1.3 Å
4cad » Glutamate-dependent intramembrane protease Rce1
lipid
lipid
  spacer   lipid
lipid
4nab » Calcium ATPase, E1-2Ca state, conformation 5 4nab » Calcium ATPase, E1-2Ca state, conformation 5
28.8 ± 1.9 Å
spacer 4j14 » Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 3
3.4 ± 1.4 Å
4j14 » Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 3
lipid
lipid
  spacer   lipid
lipid
4lxj » Lanosterol 14-alpha demethylase (CYP51) 4lxj » Lanosterol 14-alpha demethylase (CYP51)
29.8 ± 0.6 Å
spacer 4cg5 » Protein translocase Sec61, structure 1
27.2 ± 0.9 Å
4cg5 » Protein translocase Sec61, structure 1
lipid
lipid
  spacer   lipid
lipid
4cg6 » Protein translocase Sec61, structure 2 4cg6 » Protein translocase Sec61, structure 2
28.8 ± 1.2 Å
spacer 4cg7 » Protein translocase Sec61, structure 3
26.8 ± 0.3 Å
4cg7 » Protein translocase Sec61, structure 3
lipid
lipid
  spacer   lipid
lipid
2m6x » P7 viral protein 2m6x » P7 viral protein
26.8 ± 0.1 Å
spacer 4coh » Sterol 14-alpha-demethylase (CYP51), conformation 6
6.3 ± 1.3 Å
4coh » Sterol 14-alpha-demethylase (CYP51), conformation 6
lipid
lipid
  spacer   lipid
lipid
4cml » Type II inositol 1,4,5-trisphosphate 5-phosphatase 4cml » Type II inositol 1,4,5-trisphosphate 5-phosphatase
4.6 ± 1.1 Å
spacer 2lzq » NS2 protease, segment 766-789 of polyprotein
3.2 ± 2.1 Å
2lzq » NS2 protease, segment 766-789 of polyprotein
lipid
lipid
  spacer   lipid
lipid
2mkv » Na,K-ATPase regulatory protein FXYD2 2mkv » Na,K-ATPase regulatory protein FXYD2
30.6 ± 3.0 Å
spacer 4bmm » Sterol 14-alpha-demethylase (CYP51), conformation 7
8.8 ± 3.3 Å
4bmm » Sterol 14-alpha-demethylase (CYP51), conformation 7
lipid
lipid
  spacer   lipid
lipid
3weh » Squalene synthase, conformation 3 3weh » Squalene synthase, conformation 3
1.4 ± 2.5 Å
spacer 3wek » Squalene synthase, conformation 4
0.4 ± 2.5 Å
3wek » Squalene synthase, conformation 4
corner Endoplasmic reticulum membrane corner
Membrane Lipid Composition
Nat Rev Mol Cell Biol. 2008 Feb;9(2):112-24. Membrane lipids: where they are and how they behave.