PDB ID or protein name

Membrane Protein Lipid Composition Atlas

1. Archaebacterial membrane (87 proteins)
2. Bacterial Gram-negative inner membrane (465 proteins)
3. Bacterial Gram-negative outer membrane (224 proteins)
4. Bacterial Gram-positive outer membrane (10 proteins)
5. Bacterial Gram-positive plasma membrane (143 proteins)
6. Chloroplast inner membrane (2 proteins)
7. Chloroplast outer membrane (2 proteins)
8. Cytoplasmic granule membrane (1 protein)
9. Endoplasmic reticulum membrane (206 proteins)
10. Endosome membrane (55 proteins)
11. Eukaryotic plasma membrane (820 proteins)
12. Golgi membrane (32 proteins)
13. Lysosome membrane (23 proteins)
14. Mitochondrial inner membrane (73 proteins)
15. Mitochondrial outer membrane (30 proteins)
16. Nuclear inner membrane (4 proteins)
17. Nuclear outer membrane (6 proteins)
18. Peroxisome membrane (11 proteins)
19. Secreted (963 proteins)
20. Thylakoid membrane (39 proteins)
21. Undefined (117 proteins)
22. Vacuole membrane (28 proteins)
23. Vesicle membrane (21 proteins)
24. Viral membrane (88 proteins)

Lipid Composition in Endosome membrane

Endosome membrane

corner lipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipid corner
lipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipid
1dvp » Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) 1dvp » Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs)
3.0 ± 0.0 Å
spacer 1h6h » PX domain of NADH oxidase (p40phox), ligand-bound
3.9 ± 2.0 Å
1h6h » PX domain of NADH oxidase (p40phox),  ligand-bound
lipid
lipid
  spacer   lipid
lipid
1hyi » Early endosome antigen 1 (EEA1), monomer 1hyi » Early endosome antigen 1 (EEA1), monomer
3.0 ± 2.0 Å
spacer 1zvr » Myotubularin-related protein 2, monomer
3.1 ± 0.4 Å
1zvr » Myotubularin-related protein 2, monomer
lipid
lipid
  spacer   lipid
lipid
1o7k » PX domain of NADH oxidase (p47phox),  ligand-bound 1o7k » PX domain of NADH oxidase (p47phox), ligand-bound
15.2 ± 1.7 Å
spacer 1kq6 » PX domain of NADH oxidase (p47phox), ligand-free, longer chain
2.4 ± 1.6 Å
1kq6 » PX domain of NADH oxidase (p47phox),  ligand-free, longer chain
lipid
lipid
  spacer   lipid
lipid
1ocu » PX domain of sorting nexin GRD19, ligand-bound 1ocu » PX domain of sorting nexin GRD19, ligand-bound
15.3 ± 0.8 Å
spacer 1ocs » PX domain of sorting nexin GRD19, ligand-free
2.5 ± 1.1 Å
1ocs » PX domain of sorting nexin GRD19, ligand-free
lipid
lipid
  spacer   lipid
lipid
1em2 » Lipid transport protein Mln64 (StARD3) 1em2 » Lipid transport protein Mln64 (StARD3)
2.0 ± 1.1 Å
spacer 1joc » Early endosome antigen 1 (EEA1), model of dimer with lipids
15.0 ± 0.4 Å
1joc » Early endosome antigen 1 (EEA1), model of dimer with lipids
lipid
lipid
  spacer   lipid
lipid
1xte » PX domain of serine/threonine-protein kinase Sgk3 1xte » PX domain of serine/threonine-protein kinase Sgk3
1.2 ± 1.4 Å
spacer 1z2q » LM-5 FYVE domain
1.5 ± 1.5 Å
1z2q » LM-5 FYVE domain
lipid
lipid
  spacer   lipid
lipid
3fog » PX domain of sorting nexin-17 (SNX17) 3fog » PX domain of sorting nexin-17 (SNX17)
3.4 ± 1.0 Å
spacer 1fw5 » Nonstructural protein, membrane-bound domain
7.9 ± 1.5 Å
1fw5 » Nonstructural protein, membrane-bound domain
lipid
lipid
  spacer   lipid
lipid
2yw8 » RUN and FYVE domain-containing protein 1 2yw8 » RUN and FYVE domain-containing protein 1
0.7 ± 3.4 Å
spacer 3hpc » Sorting nexin-5
0.0 ± 2.1 Å
3hpc » Sorting nexin-5
lipid
lipid
  spacer   lipid
lipid
2v14 » Sorting nexin-23 (Kinesin-like protein KIF16B) 2v14 » Sorting nexin-23 (Kinesin-like protein KIF16B)
3.3 ± 3.0 Å
spacer 3p0c » Nischarin
4.1 ± 0.5 Å
3p0c » Nischarin
lipid
lipid
  spacer   lipid
lipid
2ari » Fusion peptide (512-541) of protein gp41 2ari » Fusion peptide (512-541) of protein gp41
10.0 ± 1.0 Å
spacer 2h18 » ADP-ribosylation factor-like protein 8A
1.2 ± 3.6 Å
2h18 » ADP-ribosylation factor-like protein 8A
lipid
lipid
  spacer   lipid
lipid
3tfm » Myosin X 3tfm » Myosin X
1.5 ± 2.6 Å
spacer 1jau » Juxtamembrane peptide (665-683) of protein gp41
4.0 ± 4.2 Å
1jau » Juxtamembrane peptide (665-683) of protein gp41
lipid
lipid
  spacer   lipid
lipid
1p5a » Fusion peptide (517-539) of protein gp41 1p5a » Fusion peptide (517-539) of protein gp41
25.8 ± 5.5 Å
spacer 2knu » Juxtamembrane peptide of hepatis C virus E1 glycoprotein (314-342)
5.3 ± 0.9 Å
2knu » Juxtamembrane peptide of hepatis C virus E1 glycoprotein (314-342)
lipid
lipid
  spacer   lipid
lipid
2pjv » Fusion peptide (510-532) of protein gp41 2pjv » Fusion peptide (510-532) of protein gp41
8.7 ± 3.8 Å
spacer 2pv6 » Juxtamembrane peptide (662-683) of protein gp41
6.7 ± 0.6 Å
2pv6 » Juxtamembrane peptide (662-683) of protein gp41
lipid
lipid
  spacer   lipid
lipid
2kzq » Juxtamembrane peptide (684-719) of protein gp41 2kzq » Juxtamembrane peptide (684-719) of protein gp41
4.3 ± 3.3 Å
spacer 1szi » Perilipin-3
2.4 ± 2.3 Å
1szi » Perilipin-3
lipid
lipid
  spacer   lipid
lipid
3tow » Multivesicular body subunit 12B 3tow » Multivesicular body subunit 12B
4.5 ± 2.3 Å
spacer 1vg8 » Ras-related protein Rab-7a
1.7 ± 0.5 Å
1vg8 » Ras-related protein Rab-7a
lipid
lipid
  spacer   lipid
lipid
2qpt » EH domain-containing protein 2 2qpt » EH domain-containing protein 2
4.5 ± 2.1 Å
spacer 2lqy » Peptide of envelope glycoprotein H (625-644)
3.2 ± 0.8 Å
2lqy » Peptide of envelope glycoprotein H (625-644)
lipid
lipid
  spacer   lipid
lipid
1mn8 » Matrix protein p15 1mn8 » Matrix protein p15
1.5 ± 1.8 Å
spacer 1hek » Matrix protein p15
1.0 ± 2.8 Å
1hek » Matrix protein p15
lipid
lipid
  spacer   lipid
lipid
2rsw » Fusion peptide (84-101) from E1 envelope glycoprotein 2rsw » Fusion peptide (84-101) from E1 envelope glycoprotein
8.3 ± 0.6 Å
spacer 2me1 » Juxtamembrane peptide (657-683) of protein gp160
7.7 ± 3.8 Å
2me1 » Juxtamembrane peptide (657-683) of protein gp160
lipid
lipid
  spacer   lipid
lipid
2mk3 » Probable fusion peptide (93-126, 138-160) of protein gp41 2mk3 » Probable fusion peptide (93-126, 138-160) of protein gp41
20.8 ± 0.5 Å
spacer 4cmn » Inositol polyphosphate 5-phosphatase OCRL-1
6.7 ± 1.6 Å
4cmn » Inositol polyphosphate 5-phosphatase OCRL-1
lipid
lipid
  spacer   lipid
lipid
2mj2 » Agnoprotein (17-52) 2mj2 » Agnoprotein (17-52)
22.0 ± 2.0 Å
spacer 2mk9 » Toll-like receptor 3 (698-730), dimer
27.6 ± 3.0 Å
2mk9 » Toll-like receptor 3 (698-730), dimer
lipid
lipid
  spacer   lipid
lipid
2mka » Toll-like receptor 3 (698-730), trimer 2mka » Toll-like receptor 3 (698-730), trimer
29.8 ± 1.2 Å
spacer 4on3 » PX domain of sorting nexin-10
5.2 ± 1.6 Å
4on3 » PX domain of sorting nexin-10
lipid
lipid
  spacer   lipid
lipid
2fx7 » Juxtamembrane peptide (659-685) of protein gp160 2fx7 » Juxtamembrane peptide (659-685) of protein gp160
6.2 ± 1.0 Å
spacer 4g6f » Juxtamembrane peptide (662-683) of protein gp160
4.9 ± 1.4 Å
4g6f » Juxtamembrane peptide (662-683) of protein gp160
lipid
lipid
  spacer   lipid
lipid
2me2 » Juxtamembrane peptide (651-677) of protein gp160 2me2 » Juxtamembrane peptide (651-677) of protein gp160
7.0 ± 1.1 Å
spacer 2me3 » Juxtamembrane peptide (636-662) of protein gp160
6.1 ± 0.4 Å
2me3 » Juxtamembrane peptide (636-662) of protein gp160
lipid
lipid
  spacer   lipid
lipid
2me4 » Juxtamembrane peptide (671-697) of protein gp160 2me4 » Juxtamembrane peptide (671-697) of protein gp160
7.9 ± 2.9 Å
spacer 2rum » Fusion peptide (772-787) of spike glycoprotein
11.1 ± 1.1 Å
2rum » Fusion peptide (772-787) of spike glycoprotein
lipid
lipid
  spacer   lipid
lipid
2run » Fusion peptide (1185-1201) of spike glycoprotein 2run » Fusion peptide (1185-1201) of spike glycoprotein
6.8 ± 4.0 Å
spacer 2ruo » Fusion peptide (983-887) of spike glycoprotein
9.9 ± 4.0 Å
2ruo » Fusion peptide (983-887) of spike glycoprotein
lipid
lipid
  spacer   lipid
lipid
2mg1 » Fusion peptide (683-704) of protein gp41 2mg1 » Fusion peptide (683-704) of protein gp41
30.8 ± 0.5 Å
spacer 2mg2 » Fusion peptide (671-693) of protein gp41
22.2 ± 1.9 Å
2mg2 » Fusion peptide (671-693) of protein gp41
lipid
lipid
  spacer   lipid
lipid
5tsi » Cystic fibrosis transmembrane conductance regulator 5tsi » Cystic fibrosis transmembrane conductance regulator
30.6 ± 0.8 Å
spacer 5u71 » Cystic fibrosis transmembrane conductance regulator
31.4 ± 0.6 Å
5u71 » Cystic fibrosis transmembrane conductance regulator
lipid
lipid
  spacer   lipid
lipid
5nhq » Agnoprotein (1-71) 5nhq » Agnoprotein (1-71)
7.0 ± 2.1 Å
spacer   lipid
lipid
corner Endosome membrane corner
Membrane Lipid Composition
Nat Rev Mol Cell Biol. 2008 Feb;9(2):112-24. Membrane lipids: where they are and how they behave.