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• LIPID COMPOSITION ATLAS

• Protein Classification

• Types (3 types)
• Classes (11 classes)
• Superfamilies (393 superfamilies)
• Families (668 families)
• Species (539 species)
• Localization (24 types)
• All proteins in OPM (2185 proteins)

• Protein Links

• PDB Sum,
• PDB,
• OCA,
• MPKS,
• PDBTM,
• MPDB,
• CGDB

Membrane Protein Lipid Composition Atlas

1.		Archaebacterial membrane (56 proteins)
2.		Bacterial Gram-negative inner membrane (274 proteins)
3.		Bacterial Gram-negative outer membrane (137 proteins)
4.		Bacterial Gram-positive outer membrane (7 proteins)
5.		Bacterial Gram-positive plasma membrane (81 proteins)
6.		Chloroplast inner membrane (1 protein)
7.		Chloroplast outer membrane (0 proteins)
8.		Cytoplasmic granule membrane (1 protein)
9.		Endoplasmic reticulum membrane (125 proteins)
10.		Endosome membrane (35 proteins)
11.		Eukaryotic plasma membrane (483 proteins)
12.		Golgi membrane (22 proteins)
13.		Lysosome membrane (17 proteins)
14.		Mitochondrial inner membrane (51 proteins)
15.		Mitochondrial outer membrane (20 proteins)
16.		Nuclear inner membrane (3 proteins)
17.		Nuclear outer membrane (5 proteins)
18.		Peroxisome membrane (10 proteins)
19.		Secreted (681 proteins)
20.		Thylakoid membrane (31 proteins)
21.		Undefined (75 proteins)
22.		Vacuole membrane (17 proteins)
23.		Vesicle membrane (13 proteins)
24.		Viral membrane (40 proteins)

Lipid Composition in Eukaryotic plasma membrane

Cell/Species	PC %	PE %	PI %	PS %	PA %	CL %	Sph %	Ch %	CB %	SL %	PI+PS %	PI+LPE %	LPC %	PG %
Fibroblast (NIH 3T3 cell line) Mus musculus	43.2	16.1	7.6	6.4	1.5	-	12.2	13.0	-	-	-	-	-	-
Schwann (NF1T cell line) Homo sapiens	44.0	14.0	9.6	2.8	-	-	29.6	0.6	-	-	-	-	-	-
Neuronal Cell Bodies (NS) from Cultured Dorsal Root Ganglia (embryonic day 15 rat pups) Rattus norvegicus	28.9	16.5	5.8	3.1	-	-	2.8	15.4	3.1	1.6	-	-	-	-
Neurites (NP) from Cultured Dorsal Root Ganglia (embryonic day 15 rat pups) Rattus norvegicus	27.0	22.3	6.3	6.2	-	-	4.5	22.1	5.2	2.6	-	-	-	-
Bovine Adrenal Chromaffin cells Bos taurus	48.0	32.2	-	-	-	-	9.3	-	-	-	10.4	-	-	-
Barley Roots Hordeum vulgare	36.9	32.1	-	7.1	6.3	2.0	-	-	-	-	-		5.0	3.0
Budding Yeast Saccharomyces cerevisiae	16.8	20.3	17.7	33.6	3.9	0.2	-	-	-	-	-	-	-	-
Erythrocytes Cavia porcellus	43.2	28.3	-	-	-	-	12.1	-	-	-	15.8	-	-	-
Mast Cells (RBL-2H3 rat cell line, Wistar, leukemia, basophilic) Rattus norvegicus	50.0	25.0	-	-	-	-	5.0	-	-	-	15.0	-	5.0	-
Dendritic cells Homo sapiens	43.0	23.0	-	-	-	-	9.0	-	-	-	12.0	-	13.0	-
Reticular Nucleus (RN) cells Homo sapiens	34.0	27.5	-	-	-	6.3	12.6	19.6	-	-	-	-	-	-
Human T cell Lymphotropic Virus-I (HTLV-I) carrying cells (MT-4 cell line) Homo sapiens	43.0	32.9	-	7.4	-	-	10.4	-	-	-	-	-	-	-

Eukaryotic plasma membrane

	1zhx » Oxysterol-binding protein homolog 4 (KES1) 1.2 ± 0.9 Å		2b6p » Aquaporin-0, open state 31.1 ± 1.5 Å
	3spc » Potassium channel Kir 2.2, complex with pyrophosphate lipid 30.6 ± 1.2 Å		4aq9 » Nicotinic acetylcholine receptor, partially open state 30.8 ± 0.8 Å
	3cap » Opsin, active, retinal-free state, dimer 30.8 ± 1.1 Å		2b6o » Aquaporin-0 31.8 ± 1.4 Å
	1j4n » Aquaporin-1 31.8 ± 1.0 Å		1ymg » Aquaporin-0 31.3 ± 1.2 Å
	2bg9 » Nicotinic acetylcholine receptor, closed state 30.1 ± 1.1 Å		1afo » Glycophorin A 31.9 ± 2.8 Å
	1gzm » Rhodopsin, inactive, complex with inverse agonist, 11-cis retinal 32.2 ± 1.5 Å		1z65 » N-terminal helix of prion-like protein doppel 21.0 ± 6.2 Å
	1a8a » Annexin V 2.1 ± 1.1 Å		1czs » C2 domain of coagulation factor V 3.4 ± 1.6 Å
	1h0a » Epsin-1 (ENTH domain) 3.2 ± 1.1 Å		1rlw » Cytosolic phospholipase A2, group IVA 6.4 ± 1.9 Å
	1dsy » Protein kinase C alpha, complex with phosphatidyl serine 0.9 ± 1.5 Å		1rsy » Synaptotagmin-1, C2A domain (Calcium free) 2.5 ± 1.6 Å
	1byn » Synaptotagmin-1, C2A domain (Calcium bound) 3.8 ± 1.6 Å		1uov » Synaptotagmin-1, C2B domain (Calcium bound) 1.7 ± 1.8 Å
	1mai » PH domain of phospholipase C delta 1 15.0 ± 1.8 Å		1ptr » C1 domain of protein kinase C delta 6.6 ± 1.5 Å
	2a79 » Potassium channel Kv1.2. 29.8 ± 1.5 Å		1h6i » Aquaporin-1 30.8 ± 1.1 Å
	1z98 » Aquaporin Sopip2, closed state 28.1 ± 2.2 Å		2b5f » Aquaporin Sopip2, open state 29.4 ± 1.1 Å
	2z73 » Squid rhodopsin, inactive, complex with inverse agonist 11-cis retinal, dimer 32.9 ± 1.0 Å		3c02 » Aquaglyceroporin 30.4 ± 1.3 Å
	2d57 » Aquaporin-4 29.8 ± 1.1 Å		2spc » Spectrin alpha chain 4.3 ± 0.8 Å
	1w7b » Annexin II 2.4 ± 1.2 Å		1axn » Annexin III 2.7 ± 0.8 Å
	1i4a » Annexin IV 2.5 ± 1.1 Å		1hvf » Annexin V 2.3 ± 1.5 Å
	1yii » Annexin V 3.1 ± 0.7 Å		1m9i » Annexin VI 2.8 ± 0.3 Å
	1w3w » Annexin VIII 4.1 ± 1.0 Å		1dm5 » Annexin XII 2.7 ± 1.0 Å
	1dk5 » Annexin 24 3.5 ± 1.3 Å		1n00 » Annexin GH1 1.5 ± 2.0 Å
	2p0m » Arachidonate 15-Lipoxygenase 8.6 ± 0.1 Å		2x72 » Rhodopsin, constitutively active mutant (metarhodopsin II), dimer 30.0 ± 0.6 Å
	1tfj » Glycolipid transfer protein, structure 1 3.9 ± 1.0 Å		2ks1 » Receptor tyrosine kinase erbB-2, complex with EGF receptor 32.0 ± 2.5 Å
	1wbe » Glycolipid transfer protein, structure 2 1.1 ± 2.4 Å		1dan » Coagulation factor VIIa 4.2 ± 6.0 Å
	1nl2 » Prothrombin 3.9 ± 3.0 Å		1pfx » Coagulation factor IX 1.9 ± 6.0 Å
	1lqv » Coagulation factor XIV (protein C) in complex with its receptor 3.4 ± 3.9 Å		1opb » Retinol-binding protein 2 1.9 ± 1.4 Å
	1ds6 » Rho GDP-dissociation inhibitor 2, complex with G-protein RAC2 2.8 ± 1.0 Å		1gmi » Protein kinase C epsilon 2.9 ± 1.2 Å
	3hn8 » Synaptotagmin-3 4.0 ± 3.1 Å		1ugk » Synaptotagmin-4 2.5 ± 1.7 Å
	1a25 » Protein kinase C beta 3.1 ± 1.0 Å		2bwq » Rab3 interacting molecule 2 (RIM2), C2A domain 1.5 ± 1.6 Å
	1sdd » C2 domains of coagulation factor Va 3.7 ± 2.0 Å		1d7p » C2 domain of coagulation factor VIII 4.8 ± 2.0 Å
	3fg3 » 8R-Lipoxygenase, central and C-terminal domains 5.0 ± 0.6 Å		2k1a » Integrin alpha-IIb, transmembrane helix 34.4 ± 2.6 Å
	2rmz » Integrin beta-3, transmembrane helix 30.0 ± 3.6 Å		1u5u » 8R-Lipoxygenase, N-terminal domain 3.1 ± 0.3 Å
	1hce » Hisactophilin-1 3.5 ± 1.1 Å		2knc » Integrin alpha-IIb, complex with integrin beta-3 34.8 ± 1.4 Å
	3am6 » Proton-pumping rhodopsin-2 from algae 31.2 ± 1.6 Å		2flj » Fatty acid-binding protein 1.2 ± 1.5 Å
	2rcq » Retinol-binding protein 2 2.9 ± 1.7 Å		2ksr » Nicotinic acetylcholine receptor, beta2 subunit, in hexafluoroisopropanol/water 29.1 ± 2.2 Å
	1dyn » Dynamin-1 4.1 ± 1.2 Å		1pls » Pleckstrin 3.6 ± 2.0 Å
	1foe » T-lymphoma invasion and metastasis-inducing protein 1, with G-protein RAC2 4.5 ± 1.1 Å		1fao » Dual adaptor of phosphotyrosine and 3-phosphoinositides 2.4 ± 2.0 Å
	1eaz » PH domain of TAPP1 1.7 ± 1.6 Å		1unq » Rac-alpha serine/threonine kinase 2.7 ± 2.0 Å
	1p6s » Rac-beta serine/threonine protein kinase 3.8 ± 1.8 Å		1v5u » SET binding factor 1 4.2 ± 1.5 Å
	1nty » Triple functional domain protein 3.2 ± 2.0 Å		1upr » Phosphoinositol 3-phosphate binding protein 1 3.0 ± 1.4 Å
	2bcj » PH domain of GPCR kinase 2 5.7 ± 1.5 Å		1hmt » Muscle fatty acid binding protein 4.3 ± 1.6 Å
	1bwy » Muscle fatty acid binding protein 4.8 ± 1.3 Å		1icm » Intestinal fatty acid binding protein 3.5 ± 1.5 Å
	1kzw » Intestinal fatty acid binding protein 2.9 ± 1.3 Å		1fdq » Brain fatty acid binding protein 3.1 ± 1.4 Å
	1b56 » Epidermal fatty acid binding protein 2.5 ± 2.0 Å		1a18 » Adipocyte lipid-binding protein 3.7 ± 0.8 Å
	1tow » Adipocyte lipid-binding protein 2.5 ± 1.7 Å		1o8v » Fatty acid-binding protein homolog 1 2.9 ± 1.0 Å
	1ftp » Fatty acid-binding protein 4.5 ± 1.0 Å		1cbr » Cellular retinoic acid-binding protein 1 6.5 ± 1.1 Å
	1crb » Cellular retinol-binding protein II 2.4 ± 1.7 Å		1kqw » Cellular retinol-binding protein II 3.1 ± 1.3 Å
	1ggl » Cellular retinol-binding protein III 3.3 ± 1.9 Å		1lpj » Retinoid-binding protein 7 2.6 ± 1.1 Å
	1pmp » Myelin P2 protein 2.7 ± 1.3 Å		1vyf » Fatty acid-binding protein Sm14 5.1 ± 1.2 Å
	1xwd » Follicle-stimulating hormone-receptor complex 3.1 ± 1.5 Å		2l34 » TYRO protein tyrosine kinase-binding protein, homodimer 31.8 ± 3.0 Å
	3sn6 » Beta-2 adrenergic receptor, active state, complex with G-protein 31.0 ± 1.6 Å		1djx » Phospholipase C-delta isoform 1 4.1 ± 0.9 Å
	1btq » Band 3 anion transport protein SLC4A1, fragment 405-424 13.6 ± 2.1 Å		1bts » Band 3 anion transport protein SLC4A1, fragment 436-456 9.2 ± 0.3 Å
	1ea5 » Acetylcholinesterase 1.8 ± 1.1 Å		1n5m » Acetylcholinesterase 3.7 ± 1.3 Å
	4bdt » Acetylcholinesterase, complex with fasciculin-2 10.7 ± 0.8 Å		1p0i » Butyryl cholinesterase 3.1 ± 0.8 Å
	2xu0 » Erythrocyte membrane protein 1 3.3 ± 6.0 Å		3c64 » Erythrocyte membrane protein 1 variant 5.3 ± 2.5 Å
	1c44 » Sterol carrier protein 2 3.7 ± 1.2 Å		1iou » Synaptobrevin homolog 1 3.4 ± 1.1 Å
	1jss » Cholesterol-regulated Start protein 4 (StarD4) 2.7 ± 1.4 Å		1ln1 » Phosphatidylcholine transfer protein 3.8 ± 1.8 Å
	1xq8 » Alpha-synuclein 8.7 ± 1.1 Å		1a11 » Acetylcholine receptor, subunit delta, TMH 2 24.4 ± 5.6 Å
	2b3r » Phosphatidylinositide 3-kinase C2 alpha 1.4 ± 1.5 Å		4j05 » Phosphate transporter 30.0 ± 0.5 Å
	1ann » Annexin IV, monomeric state 2.2 ± 1.0 Å		1zi7 » Oxysterol-binding protein homolog 4 (KES1), N-terminal helix removed 2.5 ± 0.5 Å
	2pso » StAR-related lipid transfer protein 13 3.1 ± 4.0 Å		1swx » Glycolipid transfer protein, conformation 2 4.6 ± 1.0 Å
	1sx6 » Glycolipid transfer protein, conformation 1 4.3 ± 1.1 Å		1hh4 » Rho GDP-dissociation inhibitor 1, complex with G-protein RAC2 4.0 ± 0.6 Å
	1qvy » Rho GDP-dissociation inhibitor 1 2.8 ± 1.7 Å		1fl7 » Follicle-stimulating hormone, complex of alpha and beta chains 2.0 ± 1.6 Å
	1zvr » Myotubularin-related protein 2 3.1 ± 0.4 Å		1dbh » Son of sevenless homolog 1 (two domains) 2.7 ± 2.8 Å
	1kbf » Kinase supressor of Ras, Ksr 1.8 ± 1.0 Å		1faq » RAF-1 proto-oncogene serine/threonine-protein kinase 4.8 ± 1.1 Å
	1tbn » Protein kinase C-gamma 4.8 ± 1.6 Å		1r79 » Diacylglycerol kinase delta 3.3 ± 1.6 Å
	1hci » Alpha-actinin-2 0.4 ± 0.7 Å		2l2t » Receptor tyrosine-protein kinase erbB-4, peptide 642-685 32.4 ± 1.5 Å
	2wut » Myelin P2 protein 4.1 ± 0.5 Å		1w1g » PH domain of 3-phosphoinositide-dependent protein kinase 1 3.8 ± 1.8 Å
	1v5p » PH domain of TAPP2 1.4 ± 1.3 Å		1nu2 » Disabled homolog 1 14.8 ± 1.1 Å
	1t27 » Phosphatidylinositol transfer protein alpha isoform 2.3 ± 1.9 Å		1uw5 » Phosphatidylinositol transfer protein alpha isoform 4.3 ± 1.5 Å
	3pwh » Adenosine receptor A2a, inactive state, engineered, complex with inverse agonist 31.0 ± 1.3 Å		1a0r » Phosducin/Transducin beta-gamma complex, conformation 1 2.3 ± 1.0 Å
	2trc » Phosducin/Transducin beta-gamma complex, conformation 2 2.2 ± 1.0 Å		1b9x » Phosducin/Transducin beta-gamma complex, conformation 3 1.0 ± 1.6 Å
	1i7e » Tubby protein, ligand-bound 3.8 ± 1.9 Å		1c8z » Tubby protein, ligand-free 2.8 ± 0.9 Å
	1hfa » Clathrin assembly lymphoid myeloid leukemia (CALM) protein 14.2 ± 2.0 Å		1bwn » PH domain of tyrosine-protein kinase BTK 15.3 ± 0.5 Å
	2cjs » Protein unc-13 homolog A, C2A domain 3.5 ± 2.0 Å		1got » Transducin 4.9 ± 1.2 Å
	2hac » Zeta-zeta dimer of T cell receptor 31.9 ± 2.3 Å		2i37 » Rhodopsin, partially active, photobleached 31.9 ± 1.5 Å
	2i36 » Rhodopsin, inactive state, a dimer 30.0 ± 1.4 Å		1fho » PH domain of muscle M-line assembly protein unc-89 2.3 ± 1.2 Å
	1u5d » PH domain of Src-associated adaptor 55 protein 4.0 ± 1.8 Å		1u5f » PH domain of Src-associated adaptor protein 2 homologue 2.2 ± 2.0 Å
	1u5e » PH domain of Src-associated adaptor protein 2 3.2 ± 2.0 Å		1xd4 » Son of sevenless homolog 1 (SOS-1) 1.9 ± 3.0 Å
	2d9v » PH domain containing retinal protein 1 1.3 ± 1.3 Å		2d9w » PH domain of docking protein 2 2.2 ± 1.2 Å
	2d9x » Oxysterol binding protein-related protein 11 1.4 ± 1.7 Å		1ksg » ADP-ribosylation factor-like protein 2, complex with human PDEdelta 6.9 ± 1.7 Å
	1fjr » Ectodomain of G-protein coupled receptor Mth 1.8 ± 1.5 Å		1doa » Rho GDP-dissociation inhibitor 1, complex with cell division control protein 42 1.1 ± 1.3 Å
	2chd » Rabphilin-3A, C2A domain 2.9 ± 1.6 Å		1yrk » Protein kinase C delta 2.0 ± 1.6 Å
	1skh » Major prion protein, segment 1-30 20.8 ± 6.3 Å		1xa6 » Beta-chimaerin 2.1 ± 1.7 Å
	1y8f » C1 domain of unc-13 homolog A 2.5 ± 1.9 Å		2db6 » C1 domanin of SH3 and cysteine-rich domain-containing protein 3 2.7 ± 0.1 Å
	1yiv » Myelin P2 protein 1.3 ± 1.7 Å		2a1l » Phosphatidylinositol transfer protein beta isoform 4.7 ± 1.7 Å
	3d3l » 12S-Lipoxygenase 5.0 ± 0.6 Å		2iqr » Melanocortin-4 receptor model (active state) with agonist NDP-MSH 33.5 ± 2.0 Å
	2iqv » Melanocortin-4 receptor model (inactive state) with antagonist AGRP 31.9 ± 1.1 Å		4ezc » Urea transporter 1 31.2 ± 0.6 Å
	4dkl » Opioid mu receptor 32.0 ± 1.0 Å		1gc6 » Radixin 15.4 ± 1.8 Å
	1btn » Spectrin beta chain 13.7 ± 1.6 Å		1fhx » Cytohesin-3 (Grp1) 15.0 ± 1.2 Å
	2qts » Acid-sensing ion channel 36.6 ± 0.9 Å		2rh1 » Beta-2 adrenergic receptor, inactive state, dimer 31.8 ± 0.9 Å
	2r9r » Potassium channel Kv1.2 - Kv2.1. chimera, in membrane-like environment 30.8 ± 0.6 Å		3b8e » Sodium-potassium pump, E2-Pi state 30.7 ± 0.9 Å
	3b8c » Plasma membrane ATPase 2, E1-ATP state 29.5 ± 1.5 Å		2jwa » Receptor tyrosine kinase erbB-2, dimer 31.9 ± 2.9 Å
	2k1k » Receptor tyrosine kinase EphA1 30.2 ± 1.5 Å		3d9s » Aquaporin-5 30.3 ± 0.9 Å
	3eml » Adenosine receptor A2a, inactive state, complex with antagonist 31.8 ± 1.2 Å		3g5u » P-glycoprotein, inward-facing conformation 31.8 ± 1.2 Å
	2k9j » Integrin alpha-IIb, complex with integrin beta-3 36.4 ± 3.3 Å		3gd8 » Aquaporin-4 29.8 ± 1.1 Å
	2zw3 » Connexin 26 gap junction channel (beta-2 protein) 32.2 ± 0.5 Å		1o6u » SEC14-like protein 2 (supernatant factor protein) 3.6 ± 1.4 Å
	1kcm » Phosphatidylinositol transfer protein alpha isoform 5.3 ± 1.4 Å		2zxe » Sodium-potassium pump, E2-Pi state 31.9 ± 1.8 Å
	2k9p » TM1-TM2 fragment of fungal STE2 receptor 29.8 ± 3.1 Å		2w2e » Aquaporin AQY1 30.2 ± 0.8 Å
	3hd7 » SNARE complex (syntaxin 1A, SNAP-25 and synaptobrevin 2) 28.5 ± 1.9 Å		3h9v » ATP-gated P2X4 ion channel, closed state 27.6 ± 1.3 Å
	2k9y » Receptor tyrosine kinase EphA2 31.8 ± 3.2 Å		2d4q » Neurofibromin 1.6 ± 2.0 Å
	2vqp » Matrix protein 2.9 ± 1.1 Å		3hd6 » Rhesus Glycoprotein RhCG 31.8 ± 0.7 Å
	3f00 » Synaptotagmin-1, C2A domain (Calcium free) 1.4 ± 1.5 Å		2nq3 » E3 ubiquitin-protein ligase Itchy homolog 3.4 ± 1.9 Å
	2r83 » Synaptotagmin-1 C2A-C2B domains 3.0 ± 1.9 Å		3fsn » Retinoid isomerohydrolase, conformation 1 7.8 ± 1.0 Å
	2klu » T-cell surface glycoprotein CD4 31.8 ± 2.6 Å		2ar5 » PX domain of C2alpha-PI3 kinase 5.6 ± 0.9 Å
	3kg2 » Glutamate receptor 2 31.8 ± 2.0 Å		2zz9 » Aquaporin-4, different conformation of loops with lipids 29.5 ± 0.7 Å
	3jyc » Potassium channel Kir 2.2 30.5 ± 1.4 Å		3kdp » Sodium-potassium pump, E2-Pi state, slightly different conf. 31.4 ± 1.4 Å
	3lnm » Potassium channel Kv1.2. - Kv2.1. chimera 31.1 ± 0.9 Å		2r55 » StAR-related lipid transfer protein 5 1.7 ± 1.2 Å
	3lut » Potassium channel Kv1.2., full-length 25.1 ± 0.5 Å		3hgc » Acid-sensitive ion channel, conformation at low pH 24.1 ± 0.7 Å
	1vry » Glycine receptor, alpha1 subunit 23.2 ± 3.7 Å		2ziy » Squid rhodopsin, inactive, complex with inverse agonist 11-cis retinal 32.9 ± 1.7 Å
	3org » ClC chloride transporter 28.7 ± 1.3 Å		3oe6 » C-X-C chemokine receptor type 4, inactive, complex with antagonist 35.3 ± 2.5 Å
	3oe0 » C-X-C chemokine receptor type 4, inactive, with cyclic peptide antagonist 32.2 ± 2.0 Å		3odu » C-X-C chemokine receptor type 4, inactive, dimer, complex with antagonist 31.2 ± 1.1 Å
	3ohm » Phospholipase C-beta isoform 3, complex with G-protein subunit alpha Q 7.5 ± 2.0 Å		2zkm » Phospholipase C-beta isoform 2 2.2 ± 2.9 Å
	1qon » Acetylcholinesterase 5.5 ± 1.6 Å		3dy5 » 8R-Lipoxygenase, complete structure 2.3 ± 1.5 Å
	1yge » Seed lipoxygenase-1 3.0 ± 2.6 Å		1rrh » Seed lipoxygenase-3 3.8 ± 1.3 Å
	2iuk » Seed lipoxygenase-D 3.7 ± 1.7 Å		2iuj » Seed lipoxygenase-B 1.7 ± 3.0 Å
	2zoc » Annexin IV 3.4 ± 1.1 Å		1avc » Annexin VI 4.4 ± 1.0 Å
	1ycn » Annexin D1 2.3 ± 1.1 Å		2zhj » Annexin IV 4.1 ± 1.0 Å
	3pbl » Dopamine D3 receptor 33.0 ± 1.8 Å		1wfm » Synaptotagmin-13 2.2 ± 1.9 Å
	2enp » Synaptotagmin-17 4.6 ± 1.5 Å		2dmg » Extended synaptotagmin-2 2.4 ± 1.0 Å
	2ep6 » Multiple C2 and transmembrane domain-containing protein 2 (MCTP2) 1.5 ± 1.5 Å		2jqz » E3 ubiquitin-protein ligase SMURF2 4.2 ± 1.8 Å
	3kwu » Protein unc-13 homolog A, C2C domain 3.3 ± 1.9 Å		2cm5 » Rabphilin-3A, C2B domain 2.5 ± 2.0 Å
	1zbd » Rabphilin-3A 3.8 ± 1.8 Å		2l35 » TYRO protein tyrosine kinase-binding protein, heterotrimer 31.6 ± 3.2 Å
	2y02 » Beta-1 adrenergic receptor, inactive, complex with agonist 31.4 ± 1.3 Å		3oax » Rhodopsin, inactive, conformation 2 30.9 ± 1.4 Å
	3p0g » Beta-2 adrenergic receptor, active state, complex with antibody 30.1 ± 1.4 Å		3pqr » Rhodopsin, active (metarhodopsin II), complex with peptide of transducin 31.8 ± 1.1 Å
	3pxo » Rhodopsin, active (metarhodopsin II), without transducin peptide, dimer 31.8 ± 1.2 Å		3qak » Adenosine receptor A2a, partially active state, complex with agonist 29.8 ± 1.2 Å
	2xzb » Sodium-potassium pump, gastric 29.7 ± 1.2 Å		3n23 » Sodium-potassium pump, different conformation 29.9 ± 0.9 Å
	3jw8 » Monoglyceride lipase MGLL, open ligand-free conformation 8.1 ± 1.3 Å		3pe6 » Monoglyceride lipase MGLL, closed ligand-bound conformation 0.9 ± 3.0 Å
	3o8y » Arachidonate 5-lipoxygenase 2.1 ± 1.0 Å		1mhs » Plasma membrane ATPase 29.5 ± 0.2 Å
	3hx3 » Retinaldehyde-binding protein 1, closed state 1.2 ± 2.9 Å		3hy5 » Retinaldehyde-binding protein 1, closed state, more complete structure 2.0 ± 3.9 Å
	2fy2 » Choline O-acetyltransferase 1.5 ± 2.2 Å		1q6x » Choline O-acetyltransferase 3.6 ± 0.6 Å
	1t1u » Choline O-acetyltransferase, different conformation 2.1 ± 1.7 Å		3mra » Acetylcholine receptor, subunit alpha, TMH 3 31.6 ± 3.3 Å
	3hl4 » Cytidylyltransferase 2.7 ± 4.0 Å		1peh » Cytidylyltransferase, first membrane-anchoring helix 3.2 ± 0.6 Å
	1pei » Cytidylyltransferase, second membrane-anchoring helix 4.9 ± 1.0 Å		2r7e » Coagulation factor VIII 4.5 ± 3.0 Å
	3biw » Neuroligin-1, complex with neurexin-1-beta 5.9 ± 1.0 Å		3bl8 » Neuroligin-2 1.7 ± 1.6 Å
	3b3q » Neuroligin-1, complex with human neurexin-1-alpha 1.8 ± 1.0 Å		2xb6 » Neuroligin-4, X-linked, complex with neurexin 1-beta 1.9 ± 3.0 Å
	1fj2 » Acyl-protein thioesterase 1 9.6 ± 2.0 Å		4ey4 » Acetylcholinesterase 3.2 ± 0.5 Å
	2qmq » Protein NDRG2 8.3 ± 2.2 Å		2xmr » Protein Ndr1 8.2 ± 2.6 Å
	3kv0 » Glycolipid transfer protein Het-c2 8.3 ± 1.3 Å		3bkr » Uncharacterized protein 0.4 ± 6.2 Å
	2qzt » Sterol carrier protein 2-like 2 1.0 ± 2.0 Å		1pz4 » Sterol carrier protein 2 0.8 ± 5.0 Å
	3rcp » PH domain of pleckstrin homology domain-containing family A member 3 2.8 ± 1.5 Å		2l9u » Receptor tyrosine-protein kinase erbB-3, peptide 640-670 33.8 ± 2.4 Å
	2ydv » Adenosine receptor A2a, partially active state, engineered, complex with agonist 31.0 ± 1.3 Å		3rhw » Glutamate-gated chloride channel GluCl alpha 30.2 ± 0.7 Å
	2ycw » Beta-1 adrenergic receptor, inactive, complex with antagonist 32.2 ± 1.3 Å		3rze » Histamine H1 receptor 32.0 ± 1.4 Å
	2k62 » Fatty acid-binding protein 0.0 ± 2.9 Å		2ftb » Fatty acid-binding protein 2 0.6 ± 2.0 Å
	2k3h » Rabphilin-3A 1.7 ± 2.1 Å		2v6v » Bud emergence protein 1 2.1 ± 1.2 Å
	1u27 » Cytohesin-2 0.5 ± 2.4 Å		1v88 » Oxysterol-binding protein-related protein 8 1.7 ± 1.2 Å
	1wgq » FYVE, RhoGEF and PH domain-containing protein 6 2.5 ± 1.8 Å		2d9y » Pleckstrin homology domain-containing family A member 6 (PLEKHA6) 1.0 ± 0.3 Å
	2da0 » Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 1.7 ± 2.5 Å		2dhi » Pleckstrin homology domain-containing family B member 2 0.6 ± 1.5 Å
	2dkp » Pleckstrin homology domain-containing family A member 5 (PLEKHA5) 3.0 ± 0.9 Å		2dx1 » Rho guanine nucleotide exchange factor 4 2.2 ± 2.2 Å
	2x18 » RAC-gamma serine/threonine-protein kinase 1.5 ± 1.1 Å		3nsu » Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1 0.8 ± 1.5 Å
	3pp2 » Rho GTPase-activating protein 27 2.5 ± 2.2 Å		3bji » Proto-oncogene vav, complex with Ras-related C3 botulinum toxin substrate 1 2.5 ± 2.2 Å
	3bib » T-cell immunoglobulin and mucin domain-containing protein 4 3.2 ± 1.9 Å		3kaa » Hepatitis A virus cellular receptor 2 homolog 2.8 ± 2.0 Å
	2or7 » T-cell immunoglobulin and mucin domain-containing protein 2 0.9 ± 0.7 Å		2or8 » Hepatitis A virus cellular receptor 1 homolog 4.2 ± 2.4 Å
	1s4x » Integrin beta-3, cytoplasmic domain 6.9 ± 1.0 Å		2ljd » Integrin beta-3, cytoplasmic domain, monophosphorylated (747pY) 8.1 ± 0.6 Å
	2lje » Integrin beta-3, cytoplasmic domain, biphosphorylated (747pY, 759pY) 4.0 ± 0.5 Å		2ljf » Integrin beta-3, cytoplasmic domain, monophosphorylated (747pY) 0.6 ± 1.6 Å
	3g9w » Integrin beta-1, complex with talin-2 8.7 ± 2.5 Å		1s4w » Integrin alpha-IIb, cytoplasmic domain 2.9 ± 0.3 Å
	2k59 » Acetylcholine receptor, subunit beta2, TMH 2 30.2 ± 1.9 Å		2k58 » Acetylcholine receptor, subunit beta2, TMH 1 30.6 ± 6.0 Å
	2kbv » Sodium/hydrogen exchanger 1, TMH XI 2.7 ± 6.9 Å		2k21 » Potassium voltage-gated channel subfamily E member 1 12.1 ± 0.4 Å
	2ki9 » Cannabinoid receptor 2, TMH 6 28.4 ± 2.2 Å		1iij » Receptor tyrosine kinase erbB-2 31.8 ± 2.8 Å
	1dxz » Acetylcholine receptor, subunit alpha, TMH II 29.8 ± 3.6 Å		1dep » Beta-1 adrenergic receptor, peptide 345-359 4.4 ± 1.2 Å
	1ho2 » Potassium voltage-gated channel protein Shaker, peptide 378-397 3.9 ± 1.2 Å		2k7y » Protein Vpu, cytoplasmic domain, in DPC micelles 4.5 ± 1.4 Å
	1vpu » Protein Vpu, cytoplasmic domain, structure in aqueous solution 7.4 ± 2.1 Å		1dsk » Viral protein R, peptide 59-86 9.5 ± 0.4 Å
	1fi0 » Viral protein R, peptide 13-33, different strain 2.7 ± 1.2 Å		1x9v » Viral protein R, peptide 52-96, dimer, different strain 7.2 ± 0.7 Å
	1m8l » Viral protein R, full length 4.7 ± 2.8 Å		3sya » G protein-activated inward rectifier potassium channel 2 (GIRK2, Kir3.2) 34.8 ± 0.7 Å
	3swh » Protein unc-13 homolog A, MHD domain 6.6 ± 3.0 Å		3ml9 » Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 3.0 ± 0.8 Å
	1e7u » Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform 2.5 ± 0.9 Å		3hhm » Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform 1.3 ± 0.5 Å
	3ls8 » Phosphatidylinositol 3-kinase catalytic subunit type 3 2.7 ± 2.2 Å		2wxf » Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, delta isoform 2.3 ± 1.8 Å
	3pyc » C2 domain of E3 ubiquitin-protein ligase SMURF1 4.5 ± 2.1 Å		3m7f » C2 domain of E3 ubiquitin-protein ligase NEDD4, complex with GRB10 2.2 ± 2.0 Å
	3b7y » C2 domain of E3 ubiquitin-protein ligase NEDD4 2.7 ± 1.5 Å		2nsq » C2 domain of E3 ubiquitin-protein ligase NEDD4-like 1.8 ± 1.1 Å
	2x77 » ADP-ribosylation factor-like protein 1 1.6 ± 1.4 Å		1z6y » ADP-ribosylation factor-like protein 5A 1.5 ± 1.9 Å
	3ik5 » Protein Nef, complex with T-cell surface glycoprotein CD3 zeta chain 3.1 ± 0.5 Å		2nef » Protein Nef (HIV HV1LW) 6.3 ± 1.4 Å
	1zec » Protein Nef, N-terminal helix (HIV HV1B1) 3.6 ± 4.1 Å		1avv » Protein Nef 3.0 ± 1.5 Å
	2xi1 » Protein Nef (HIV 9HIV1) 4.3 ± 0.6 Å		3rbb » Protein Nef, complex with tyrosine-protein kinase SH3 domain (HIV HV1A2) 2.4 ± 1.1 Å
	4a60 » Fatty acid-binding protein 9 3.2 ± 1.1 Å		3elz » Fatty acid binding protein 6, ileal (Gastrotropin) 1.1 ± 0.9 Å
	2lbg » Major prion protein, peptide 110-136 5.0 ± 7.0 Å		2iv5 » Major prion protein, peptide 173-195 5.3 ± 4.1 Å
	2rnd » Myc box-dependent-interacting protein 1, membrane anchor helix (peptide 1-33) 4.0 ± 0.4 Å		2kgn » Protein STE5, peptide 44-67 6.4 ± 0.9 Å
	1hod » Second intracellular loop (118-149) of alpha-2A adrenergic receptor 3.9 ± 4.1 Å		1ba4 » Amyloid beta A4 protein (peptide 672-711) 6.0 ± 0.3 Å
	1z9i » Juxtamembrane peptide of epidermal growth factor receptor 4.7 ± 1.6 Å		2rlj » Fusion peptide (524-539) of ebolavirus envelope glycoprotein 5.8 ± 1.8 Å
	1kdl » Anchor helix of protein yopD (peptide 278-300) 5.7 ± 0.8 Å		1kzt » Viral protein R, peptide 34-51 7.4 ± 0.6 Å
	2k44 » Voltage sensor of calcium-activated potassium channel 7.5 ± 3.0 Å		2ky5 » Peptide (686-738) of platelet endothelial cell adhesion molecule 1.0 ± 3.8 Å
	3oai » Myelin protein P0 2.2 ± 1.2 Å		1neu » Myelin protein P0 5.4 ± 1.8 Å
	2l73 » NADPH oxidase organizer 1, PX domain 2.8 ± 1.9 Å		3ug9 » Archaeal-type opsin 2 31.0 ± 1.2 Å
	1kil » Complexin/SNARE complex 4.0 ± 2.0 Å		2kog » Vesicle-associated membrane protein 2 34.8 ± 1.7 Å
	1ipe » Tropinone reductase 2 3.3 ± 0.7 Å		1p33 » Pteridine reductase 1 3.4 ± 1.0 Å
	1p4o » Insulin-like growth factor 1 receptor 2.4 ± 1.0 Å		3bea » Macrophage colony-stimulating factor 1 receptor 2.9 ± 1.5 Å
	2j0k » Focal adhesion kinase 1 5.0 ± 2.1 Å		2wf1 » Beta-secretase 1 1.7 ± 1.2 Å
	1s31 » Tubby protein homolog 6.8 ± 1.0 Å		3nve » Major prion protein, peptide 138-143 3.6 ± 0.4 Å
	3nvf » Major prion protein, peptide 138-143 6.9 ± 0.2 Å		1c3i » Stromelysin-1 3.6 ± 1.7 Å
	1eak » 72 kDa type IV collagenase 4.1 ± 1.6 Å		1gxd » 72 kDa type IV collagenase complex 2.5 ± 1.1 Å
	1ck7 » 72 kDa type IV collagenase 2.9 ± 1.7 Å		3ije » Integrin beta-3/alpha-V complex 6.1 ± 2.1 Å
	2dtc » Ras-specific guanine nucleotide-releasing factor 2.7 ± 0.4 Å		2dfk » Rho guanine nucleotide exchange factor 9 complex 2.8 ± 2.7 Å
	2q63 » Retropepsin 4.5 ± 0.4 Å		2b7z » HIV-1 protease 3.4 ± 1.4 Å
	2lm2 » Nicotinic acetylcholine receptor, beta2 subunit, in LDAO micelles 29.2 ± 1.6 Å		1d01 » TNF receptor-associated factor 2 3.5 ± 0.0 Å
	1dqt » Cytotoxic T-lymphocyte protein 4 3.4 ± 1.6 Å		1url » Sialoadhesin 3.7 ± 1.8 Å
	1yjd » T-cell-specific surface glycoprotein CD28 4.5 ± 0.6 Å		2if7 » SLAM family member 6 2.0 ± 3.3 Å
	1ik7 » Serine/threonine-protein kinase pelle 1.5 ± 3.7 Å		3g5b » Netrin receptor UNC5B 1.9 ± 2.5 Å
	1jcr » Protein farnesyltransferase/geranylgeranyltransferase 3.2 ± 2.3 Å		2h6f » Protein farnesyltransferase/geranylgeranyltransferase 4.5 ± 1.5 Å
	1m6b » Receptor tyrosine-protein kinase erbB-3, extracellular domains 2.0 ± 1.6 Å		1n8y » Receptor tyrosine-protein kinase erbB-2 3.4 ± 3.0 Å
	1osc » Protein CutA 1.3 ± 0.3 Å		1rkp » cGMP-specific 3',5'-cyclic phosphodiesterase 5.0 ± 1.6 Å
	3n9v » Type II inositol-1,4,5-trisphosphate 5-phosphatase 4.1 ± 1.4 Å		1suj » Cone arrestin 1.4 ± 0.8 Å
	1v3e » Hemagglutinin-neuraminidase glycoprotein 1.9 ± 0.4 Å		1vf6 » PALS1-associated tight junction protein 5.8 ± 0.4 Å
	1wms » Ras-related protein Rab-9A 1.9 ± 0.8 Å		1xtq » GTP-binding protein Rheb 2.6 ± 0.6 Å
	2p2l » Ras-related C3 botulinum toxin substrate 1 3.2 ± 0.8 Å		3p1w » RabGDI protein 6.6 ± 1.4 Å
	3lxr » Transforming protein RhoA 2.7 ± 0.4 Å		2wnp » Ficolin-1 3.0 ± 0.8 Å
	2z64 » Toll-like receptor 4 complex 1.1 ± 3.1 Å		2hew » Tumor necrosis factor ligand superfamily member 4 1.7 ± 0.3 Å
	2vj2 » Protein jagged-1 3.4 ± 1.8 Å		2w4j » Death-associated protein kinase 1 2.1 ± 0.7 Å
	2w4o » Calcium/calmodulin-dependent protein kinase type IV 3.2 ± 1.2 Å		2w5a » Serine/threonine-protein kinase Nek2 2.7 ± 1.5 Å
	2w61 » 1,3-beta-glucanosyltransferase GAS2 2.4 ± 2.3 Å		2w62 » 1,3-beta-glucanosyltransferase GAS2, different conformation 2.7 ± 0.5 Å
	3f6y » ADP-ribosyl cyclase 1 2.5 ± 2.4 Å		3mx7 » Fas apoptotic inhibitory molecule 1 4.2 ± 1.4 Å
	3n1f » Cell adhesion molecule complex 5.2 ± 0.9 Å		3nce » Prolactin receptor 3.4 ± 1.5 Å
	3p2t » Leukocyte immunoglobulin-like receptor subfamily B member 4 1.7 ± 0.4 Å		3qni » Protein kinase C and casein kinase substrate 3.0 ± 0.0 Å
	3qw9 » Transforming growth factor beta receptor type 3 3.1 ± 0.3 Å		2l8s » Integrin alpha-1 32.0 ± 3.7 Å
	4gbr » Beta-2 adrenergic receptor, inactive state 31.6 ± 1.3 Å		2vt4 » Beta-1 adrenergic receptor, inactive, multiple mutations 32.8 ± 1.6 Å
	1pi7 » Protein Vpu, transmembrane helix 28.2 ± 5.4 Å		3uon » Muscarinic acetylcholine receptor M2 31.8 ± 2.1 Å
	3vga » Adenosine receptor A2a, complex with antibody 30.4 ± 1.4 Å		2lnq » Amyloid beta A4 protein, peptide 672-711 6.3 ± 2.0 Å
	3um7 » Potassium channel subfamily K member 4 30.8 ± 1.2 Å		3ukm » Potassium channel subfamily K member 1 31.8 ± 1.0 Å
	3v2y » Sphingosine 1-phosphate receptor 1 32.2 ± 1.4 Å		4daj » Muscarinic acetylcholine receptor M3 32.2 ± 1.2 Å
	4djh » Opioid kappa receptor 32.0 ± 0.8 Å		3uza » Adenosine receptor A2a, complex with antagonist 31.6 ± 0.6 Å
	2lly » Nicotinic acetylcholine receptor, alpha4 subunit, in LDAO micelles 29.2 ± 1.2 Å		4ea3 » Nociceptin receptor 32.0 ± 1.2 Å
	4dw1 » ATP-gated P2X4 ion channel, open state 26.8 ± 0.6 Å		3v99 » Arachidonate 5-lipoxygenase, complex with arachidonic acid 3.0 ± 2.3 Å
	4ej4 » Opioid delta receptor 34.4 ± 0.8 Å		2ld2 » Peptide of huntigtin, 1-17 4.2 ± 0.6 Å
	2loh » Amyloid beta A4 protein, peptide 686-726, dimer 32.8 ± 1.6 Å		2lom » HIG1 domain family member 1A 22.0 ± 5.0 Å
	2lon » HIG1 domain family member 1B 22.4 ± 1.2 Å		2l6w » Platelet-derived growth factor receptor beta, 526-563 34.8 ± 0.8 Å
	2kyt » Group XVI phospholipase A1/A2 4.1 ± 1.5 Å		2lp1 » Amyloid beta A4 protein (peptide 671-770) 23.6 ± 5.6 Å
	2ls2 » High affinity copper uptake protein 1, peptide 64-84 25.2 ± 4.2 Å		2ls3 » High affinity copper uptake protein 1, peptide 132-157 20.8 ± 3.4 Å
	2ls4 » High affinity copper uptake protein 1, peptide 156-179 4.9 ± 0.7 Å		4f7h » Fermitin family homolog 2 2.2 ± 1.4 Å
	2llm » Amyloid beta A4 protein, peptide 686-726 32.8 ± 2.2 Å		3spg » Potassium channel Kir 2.2, complex with inositol lipid 30.8 ± 1.2 Å
	4eiy » Adenosine receptor A2a, inactive state, with annular lipids 32.2 ± 1.2 Å		3m9i » Aquaporin-0, alternative packing with lipids 27.6 ± 1.4 Å
	2lx0 » Fusion protein p14, FAST 27.4 ± 2.3 Å		2lug » Myelin basic protein 5.6 ± 1.5 Å
	4f4c » Multidrug resistance protein pgp-1 32.0 ± 1.8 Å		4f2z » Retinoid isomerohydrolase, conformation 2 3.7 ± 0.9 Å
	4f30 » Retinoid isomerohydrolase, conformation 3 3.4 ± 1.4 Å		4grv » Neurotensin receptor type 1 31.6 ± 1.1 Å
	2lnl » C-X-C chemokine receptor type 1 30.2 ± 0.9 Å		2yn9 » Sodium-potassium pump, gastric, different conformation 30.6 ± 0.8 Å
	4hkr » Calcium release-activated calcium channel protein 1 30.0 ± 1.6 Å		3vw7 » Thrombin (proteinase-activated) receptor 1, PAR1 33.4 ± 1.9 Å
	2low » Apelin receptor, peptide 1-55 26.4 ± 5.1 Å		4i9w » Potassium channel subfamily K member 4, different conformation 30.8 ± 1.4 Å
	4al0 » Microsomal prostaglandin E synthase 1, different conformation 28.8 ± 1.0 Å		2m20 » Epidermal growth factor receptor, erbB-1, homodimer (642-697) 34.0 ± 3.0 Å
	4gpo » Beta-1 adrenergic receptor, inactive, dimer 30.8 ± 1.2 Å		4ib4 » 5-hydroxytryptamine receptor 2B 34.0 ± 2.3 Å
	4iar » 5-hydroxytryptamine receptor 1B, conformation 1 33.6 ± 1.8 Å		4iaq » 5-hydroxytryptamine receptor 1B, conformation 2 34.4 ± 1.7 Å
	1u19 » Rhodopsin, inactive, conformation 3 31.2 ± 1.5 Å		3syq » G protein-activated inward rectifier potassium channel 2, diff. conf. 31.6 ± 0.6 Å
	3cll » Aquaporin Sopip2, closed state 2 29.8 ± 0.7 Å		4ezk » Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, more complete 3.6 ± 0.6 Å
	4jkv » Smoothened homolog 31.9 ± 1.2 Å		4ikb » Sorting nexin-11, conformation 1 5.2 ± 2.7 Å
	4ikd » Sorting nexin-11, conformation 2 3.0 ± 1.2 Å		2m7w » Na(+)/H(+) antiporter, TMH IV, fusion construct 26.8 ± 0.1 Å
	2m7x » Na(+)/H(+) antiporter, TMH IV 23.0 ± 3.1 Å		4jtc » Potassium channel Kv1.2. - Kv2.1. chimera, complex with Charybdotoxin 30.2 ± 0.4 Å
	4kfm » G protein-activated inward rectifier potassium channel 2 33.6 ± 1.2 Å
	Eukaryotic plasma membrane

Nat Rev Mol Cell Biol. 2008 Feb;9(2):112-24. Membrane lipids: where they are and how they behave.

Copyright © 2005-2013 Andrei Lomize, Mikhail Lomize and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA