PDB ID or protein name

Membrane Protein Lipid Composition Atlas

1. Archaebacterial membrane (87 proteins)
2. Bacterial Gram-negative inner membrane (440 proteins)
3. Bacterial Gram-negative outer membrane (224 proteins)
4. Bacterial Gram-positive outer membrane (10 proteins)
5. Bacterial Gram-positive plasma membrane (142 proteins)
6. Chloroplast inner membrane (2 proteins)
7. Chloroplast outer membrane (2 proteins)
8. Cytoplasmic granule membrane (1 protein)
9. Endoplasmic reticulum membrane (201 proteins)
10. Endosome membrane (54 proteins)
11. Eukaryotic plasma membrane (795 proteins)
12. Golgi membrane (32 proteins)
13. Lysosome membrane (23 proteins)
14. Mitochondrial inner membrane (72 proteins)
15. Mitochondrial outer membrane (30 proteins)
16. Nuclear inner membrane (4 proteins)
17. Nuclear outer membrane (6 proteins)
18. Peroxisome membrane (11 proteins)
19. Secreted (954 proteins)
20. Thylakoid membrane (39 proteins)
21. Undefined (116 proteins)
22. Vacuole membrane (27 proteins)
23. Vesicle membrane (21 proteins)
24. Viral membrane (87 proteins)

Lipid Composition in Lysosome membrane

Lysosome membrane

corner lipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipid corner
lipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipid
1n69 » Saposin B (peptide 195-273), structure 1 1n69 » Saposin B (peptide 195-273), structure 1
1.2 ± 1.0 Å
spacer 1lyb » Cathepsin D
7.0 ± 0.6 Å
1lyb » Cathepsin D
lipid
lipid
  spacer   lipid
lipid
1tjj » Ganglioside GM2 activator 1tjj » Ganglioside GM2 activator
4.2 ± 0.3 Å
spacer 2agc » Ganglioside GM2 activator
3.2 ± 1.0 Å
2agc » Ganglioside GM2 activator
lipid
lipid
  spacer   lipid
lipid
1ogs » Glucosylceramidase 1ogs » Glucosylceramidase
4.2 ± 1.1 Å
spacer 1eh5 » Palmitoyl protein thioesterase 1
5.3 ± 0.9 Å
1eh5 » Palmitoyl protein thioesterase 1
lipid
lipid
  spacer   lipid
lipid
1pja » Palmitoyl protein thioesterase 2 1pja » Palmitoyl protein thioesterase 2
3.7 ± 1.6 Å
spacer 1pub » Ganglioside GM2 activator, different conformation
4.9 ± 0.7 Å
1pub » Ganglioside GM2 activator, different conformation
lipid
lipid
  spacer   lipid
lipid
2ag4 » Ganglioside GM2 activator, apo-protein 2ag4 » Ganglioside GM2 activator, apo-protein
3.1 ± 1.3 Å
spacer 1sn6 » Saposin C (peptide 311-391)
4.8 ± 1.1 Å
1sn6 » Saposin C (peptide 311-391)
lipid
lipid
  spacer   lipid
lipid
2vt0 » Glucosylceramidase 2vt0 » Glucosylceramidase
2.3 ± 1.0 Å
spacer 3gro » Palmitoyl-protein thioesterase 1
3.6 ± 0.1 Å
3gro » Palmitoyl-protein thioesterase 1
lipid
lipid
  spacer   lipid
lipid
2dob » Saposin A (peptide 60-140) 2dob » Saposin A (peptide 60-140)
2.0 ± 2.5 Å
spacer 3zr5 » Galactocerebrosidase
5.2 ± 0.6 Å
3zr5 » Galactocerebrosidase
lipid
lipid
  spacer   lipid
lipid
1m6d » Cathepsin F 1m6d » Cathepsin F
4.3 ± 0.8 Å
spacer 3fgr » Phospholipase B-like protein
6.5 ± 2.4 Å
3fgr » Phospholipase B-like protein
lipid
lipid
  spacer   lipid
lipid
4ddj » Saposin A (peptide 60-140), conformation in disc 4ddj » Saposin A (peptide 60-140), conformation in disc
6.4 ± 0.9 Å
spacer 2mom » Lysosome-associated membrane glycoprotein 2, homotrimer
36.5 ± 3.8 Å
2mom » Lysosome-associated membrane glycoprotein 2, homotrimer
lipid
lipid
  spacer   lipid
lipid
2mof » Lysosome-associated membrane glycoprotein 2, monomer 2mof » Lysosome-associated membrane glycoprotein 2, monomer
30.6 ± 3.5 Å
spacer 4wy4 » Vesicle-associated membrane protein 8 (VAMP8)- Syntaxin-17 complex
6.8 ± 1.3 Å
4wy4 » Vesicle-associated membrane protein 8 (VAMP8)- Syntaxin-17 complex
lipid
lipid
  spacer   lipid
lipid
4x90 » Group XV phospholipase A2 4x90 » Group XV phospholipase A2
1.9 ± 0.5 Å
spacer 5i31 » Niemann-Pick C1 protein, NPC1
30.8 ± 0.0 Å
5i31 » Niemann-Pick C1 protein, NPC1
lipid
lipid
  spacer   lipid
lipid
4v2o » Saposin B (peptide 195-273), structure 2 4v2o » Saposin B (peptide 195-273), structure 2
1.5 ± 1.0 Å
spacer   lipid
lipid
corner Lysosome membrane corner
Membrane Lipid Composition
Nat Rev Mol Cell Biol. 2008 Feb;9(2):112-24. Membrane lipids: where they are and how they behave.