PDB ID or protein name

Membrane Protein Lipid Composition Atlas

1. Archaebacterial membrane (87 proteins)
2. Bacterial Gram-negative inner membrane (440 proteins)
3. Bacterial Gram-negative outer membrane (224 proteins)
4. Bacterial Gram-positive outer membrane (10 proteins)
5. Bacterial Gram-positive plasma membrane (142 proteins)
6. Chloroplast inner membrane (2 proteins)
7. Chloroplast outer membrane (2 proteins)
8. Cytoplasmic granule membrane (1 protein)
9. Endoplasmic reticulum membrane (201 proteins)
10. Endosome membrane (54 proteins)
11. Eukaryotic plasma membrane (795 proteins)
12. Golgi membrane (32 proteins)
13. Lysosome membrane (23 proteins)
14. Mitochondrial inner membrane (72 proteins)
15. Mitochondrial outer membrane (30 proteins)
16. Nuclear inner membrane (4 proteins)
17. Nuclear outer membrane (6 proteins)
18. Peroxisome membrane (11 proteins)
19. Secreted (954 proteins)
20. Thylakoid membrane (39 proteins)
21. Undefined (116 proteins)
22. Vacuole membrane (27 proteins)
23. Vesicle membrane (21 proteins)
24. Viral membrane (87 proteins)

Lipid Composition in Vacuole membrane

Cell/Species PC % PE % PI % PS % PA % CL % Sph % Ch % CB % SL % PI+PS % PI+LPE % LPC % PG %
Barley Roots
Hordeum vulgare
53.6 23.0 - 2.9 1.9 0.6 - - - - - 3.2 6.0
Budding Yeast
Saccharomyces cerevisiae
46.5 19.4 18.3 4.4 2.1 1.6 - - - - - - - -

Vacuole membrane

corner lipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipid corner
lipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipid
1vfy » FYVE domain of Vps27 protein 1vfy » FYVE domain of Vps27 protein
3.7 ± 1.8 Å
spacer 1qqe » Vesicular transport protein sec17
5.2 ± 6.1 Å
1qqe » Vesicular transport protein sec17
lipid
lipid
  spacer   lipid
lipid
1qdm » Phytepsin 1qdm » Phytepsin
9.9 ± 1.1 Å
spacer 1qs8 » Plasmepsin IV
9.1 ± 1.5 Å
1qs8 » Plasmepsin IV
lipid
lipid
  spacer   lipid
lipid
1vtp » Proteinase inhibitor, vacuolar targeting peptide (372-397) 1vtp » Proteinase inhibitor, vacuolar targeting peptide (372-397)
3.5 ± 1.1 Å
spacer 1kmd » PX domain of vacuolar morphogenesis protein VAM7
3.4 ± 1.2 Å
1kmd » PX domain of vacuolar morphogenesis protein VAM7
lipid
lipid
  spacer   lipid
lipid
3l0m » DrrA protein, PtdIns(4) binding domain, from different strain 3l0m » DrrA protein, PtdIns(4) binding domain, from different strain
3.7 ± 4.2 Å
spacer 3dan » Plant cytochrome P450 74A (allene oxide synthase)
7.5 ± 0.4 Å
3dan » Plant cytochrome P450 74A (allene oxide synthase)
lipid
lipid
  spacer   lipid
lipid
3n6o » DrrA protein, PtdIns(4) binding domain 3n6o » DrrA protein, PtdIns(4) binding domain
5.1 ± 1.4 Å
spacer 2kit » Serine/threonine-protein kinase TOR1, FATC domain
6.3 ± 1.0 Å
2kit » Serine/threonine-protein kinase TOR1, FATC domain
lipid
lipid
  spacer   lipid
lipid
2jtw » V-type proton ATPase subunit a, vacuolar isoform, TMH 7 2jtw » V-type proton ATPase subunit a, vacuolar isoform, TMH 7
20.8 ± 6.5 Å
spacer 1fq5 » Saccharopepsin
3.8 ± 0.8 Å
1fq5 » Saccharopepsin
lipid
lipid
  spacer   lipid
lipid
1lf2 » Plasmepsin-2 1lf2 » Plasmepsin-2
6.2 ± 0.4 Å
spacer 4a01 » Proton-translocating pyrophosphatase, structure 1
32.0 ± 0.8 Å
4a01 » Proton-translocating pyrophosphatase, structure 1
lipid
lipid
  spacer   lipid
lipid
3kl4 » Signal recognition 54 kDa protein 3kl4 » Signal recognition 54 kDa protein
9.7 ± 0.5 Å
spacer 4fyg » SidF, inhibitor of growth family, member 3
8.1 ± 3.3 Å
4fyg » SidF, inhibitor of growth family, member 3
lipid
lipid
  spacer   lipid
lipid
5tj5 » V-type proton ATPase, vacuolar 5tj5 » V-type proton ATPase, vacuolar
35.8 ± 0.2 Å
spacer 4k1c » Vacuolar calcium ion transporter
29.8 ± 1.0 Å
4k1c » Vacuolar calcium ion transporter
lipid
lipid
  spacer   lipid
lipid
4mxp » DrrA protein, PtdIns(4) binding domain, complex with PtdIns(4) 4mxp » DrrA protein, PtdIns(4) binding domain, complex with PtdIns(4)
2.8 ± 2.6 Å
spacer 4jza » Legionalla phosphoinositide phosphatase, SidP
2.6 ± 1.7 Å
4jza » Legionalla phosphoinositide phosphatase, SidP
lipid
lipid
  spacer   lipid
lipid
2mvh » Stage V sporulation protein M 2mvh » Stage V sporulation protein M
6.3 ± 1.0 Å
spacer 3j9t » V-type proton ATPase, vacuolar, state 1
39.6 ± 1.3 Å
3j9t » V-type proton ATPase, vacuolar, state 1
lipid
lipid
  spacer   lipid
lipid
3j9u » V-type proton ATPase, vacuolar, state 2 3j9u » V-type proton ATPase, vacuolar, state 2
40.4 ± 1.1 Å
spacer 3j9v » V-type proton ATPase, vacuolar, state 3
40.0 ± 1.2 Å
3j9v » V-type proton ATPase, vacuolar, state 3
lipid
lipid
  spacer   lipid
lipid
5dqq » Two pore calcium channel TPC1 5dqq » Two pore calcium channel TPC1
29.8 ± 0.5 Å
spacer 5i32 » Aquaporin TIP2-1
30.0 ± 0.8 Å
5i32 » Aquaporin TIP2-1
lipid
lipid
  spacer   lipid
lipid
5gpj » Proton-translocating pyrophosphatase, structure 2 5gpj » Proton-translocating pyrophosphatase, structure 2
31.0 ± 0.4 Å
spacer   lipid
lipid
corner Vacuole membrane corner
Membrane Lipid Composition
Nat Rev Mol Cell Biol. 2008 Feb;9(2):112-24. Membrane lipids: where they are and how they behave.