PDB ID or protein name

Membrane Protein Lipid Composition Atlas

1. Archaebacterial membrane (87 proteins)
2. Bacterial Gram-negative inner membrane (451 proteins)
3. Bacterial Gram-negative outer membrane (224 proteins)
4. Bacterial Gram-positive outer membrane (10 proteins)
5. Bacterial Gram-positive plasma membrane (142 proteins)
6. Chloroplast inner membrane (2 proteins)
7. Chloroplast outer membrane (2 proteins)
8. Cytoplasmic granule membrane (1 protein)
9. Endoplasmic reticulum membrane (203 proteins)
10. Endosome membrane (54 proteins)
11. Eukaryotic plasma membrane (800 proteins)
12. Golgi membrane (32 proteins)
13. Lysosome membrane (23 proteins)
14. Mitochondrial inner membrane (73 proteins)
15. Mitochondrial outer membrane (30 proteins)
16. Nuclear inner membrane (4 proteins)
17. Nuclear outer membrane (6 proteins)
18. Peroxisome membrane (11 proteins)
19. Secreted (958 proteins)
20. Thylakoid membrane (39 proteins)
21. Undefined (116 proteins)
22. Vacuole membrane (27 proteins)
23. Vesicle membrane (21 proteins)
24. Viral membrane (88 proteins)

Lipid Composition in Vesicle membrane

Cell/Species PC % PE % PI % PS % PA % CL % Sph % Ch % CB % SL % PI+PS % PI+LPE % LPC % PG %
Budding Yeast
Saccharomyces cerevisiae
35.0 22.3 19.1 12.9 1.2 0.7 - - - - - - - -

Vesicle membrane

corner lipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipid corner
lipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipidlipid
1hm6 » Annexin I 1hm6 » Annexin I
2.1 ± 0.9 Å
spacer 2xa7 » Subunit mu of AP-2 clatrin adaptor complex, open conformation
3.1 ± 2.2 Å
2xa7 » Subunit mu of AP-2 clatrin adaptor complex, open conformation
lipid
lipid
  spacer   lipid
lipid
1auv » Synapsin I 1auv » Synapsin I
1.9 ± 1.1 Å
spacer 1cjy » Cytosolic phospholipase A2, group IVA
5.8 ± 1.0 Å
1cjy » Cytosolic phospholipase A2, group IVA
lipid
lipid
  spacer   lipid
lipid
5ixc » Cytosolic phospholipase A2 delta, structure 1 5ixc » Cytosolic phospholipase A2 delta, structure 1
5.5 ± 2.0 Å
spacer 1x4u » FYVE domain of protein 27
4.3 ± 1.9 Å
1x4u » FYVE domain of protein 27
lipid
lipid
  spacer   lipid
lipid
1wfk » FYVE domain of protein 19 1wfk » FYVE domain of protein 19
4.3 ± 1.8 Å
spacer 3lll » Protein kinase C and casein kinase substrate
1.9 ± 0.4 Å
3lll » Protein kinase C and casein kinase substrate
lipid
lipid
  spacer   lipid
lipid
3nsj » Perforin-1 3nsj » Perforin-1
3.1 ± 1.0 Å
spacer 3fdw » Synaptotagmin-like protein 4
3.0 ± 2.0 Å
3fdw » Synaptotagmin-like protein 4
lipid
lipid
  spacer   lipid
lipid
2d8k » Synaptotagmin-7 2d8k » Synaptotagmin-7
2.8 ± 1.3 Å
spacer 3l9b » C2 domain of otoferlin
2.4 ± 5.2 Å
3l9b » C2 domain of otoferlin
lipid
lipid
  spacer   lipid
lipid
3n5a » Synaptotagmin-7 3n5a » Synaptotagmin-7
2.2 ± 2.3 Å
spacer 2vj0 » AP-2 complex
2.6 ± 2.0 Å
2vj0 » AP-2 complex
lipid
lipid
  spacer   lipid
lipid
3kyq » Synaptobrevin homolog YKT6 3kyq » Synaptobrevin homolog YKT6
2.5 ± 2.0 Å
spacer 2lsw » N-terminal peptide (24-58) of Disabled homolog 2
2.1 ± 0.6 Å
2lsw » N-terminal peptide (24-58) of Disabled homolog 2
lipid
lipid
  spacer   lipid
lipid
4x9p » Annexin A2 4x9p » Annexin A2
2.7 ± 2.4 Å
spacer 5a4h » Lipid droplet anchoring peptide of CGI-58
3.9 ± 1.2 Å
5a4h » Lipid droplet anchoring peptide of CGI-58
lipid
lipid
  spacer   lipid
lipid
5iz5 » Cytosolic phospholipase A2 delta, structure 2 5iz5 » Cytosolic phospholipase A2 delta, structure 2
1.0 ± 0.0 Å
spacer 5h37 » Capsid envelop protein complex, Zika, structure 3
25.8 ± 0.0 Å
5h37 » Capsid envelop protein complex, Zika, structure 3
lipid
lipid
  spacer   lipid
lipid
5h4y » C2A domain of synaptotagmin-5 5h4y » C2A domain of synaptotagmin-5
2.3 ± 2.3 Å
spacer   lipid
lipid
corner Vesicle membrane corner
Membrane Lipid Composition
Nat Rev Mol Cell Biol. 2008 Feb;9(2):112-24. Membrane lipids: where they are and how they behave.