• HOME
• ABOUT OPM
• DOWNLOAD OPM FILES
• CONTACT US
• PPM SERVER
• LIPID COMPOSITION ATLAS

• Protein Classification

• Types (3 types)
• Classes (11 classes)
• Superfamilies (392 superfamilies)
• Families (667 families)
• Species (538 species)
• Localization (24 types)
• All proteins in OPM (2172 proteins)

• Protein Links

• PDB Sum,
• PDB,
• OCA,
• MPKS,
• PDBTM,
• MPDB,
• CGDB

Transmembrane classes

1.1.		Alpha-helical polytopic (72 superfamilies)
1.2.		Alpha-helical bitopic (42 superfamilies)
1.3.		Beta-barrel transmembrane (26 superfamilies)

See list of these PDB codes

Transmembrane (819 proteins)

Family	Protein Name	PDB ID	Species	Localization	Num. Subunits	Num. TM Sec. Structs.	Hydrophobic Thickness or Depth (Å)	Tilt Angle (°)	ΔGtransfer (kcal/mol)
1.3.01.02.	Outer membrane protein X (OMPX)	1qj8	Escherichia coli	Bact. Gram-neg outer	1	8	23.6 ± 2.8	12 ± 5	-30.7
1.1.12.01.	Potassium channel KvAP, sensor domain, NMR model	2kyh	Aeropyrum pernix	Archaebac.	1	5	28.6 ± 1.4	19 ± 4	-44.6
1.2.39.02.	Stromelysin-1	1c3i	Homo sapiens	Eukaryo. plasma	1	0	3.6 ± 1.7	85 ± 17	-4.4
1.1.56.01.	Glycerol phosphate lipoteichoic acid synthase	2w5q	Staphylococcus aureus	Bact. Gram-pos plas.	1	0	0.4 ± 3.6	82 ± 11	-2.5
1.2.01.01.	Receptor tyrosine-protein kinase erbB-3, extracellular domains	1m6b	Homo sapiens	Eukaryo. plasma	1	0	2.0 ± 1.6	45 ± 5	-3.9
1.3.20.01.	Ferric hydroxamate uptake receptor FhuA	1qfg	Escherichia coli	Bact. Gram-neg outer	1	22	24.7 ± 1.0	5 ± 1	-81.3
1.2.05.01.	Internalin C	1xeu	Listeria monocytogenes	Bact. Gram-pos plas.	1	0	2.9 ± 1.3	81 ± 0	-4.1
1.1.64.01.	Sodium/calcium exchanger, different conformation	3v5s	Methanococcus jannaschii	Archaebac.	1	10	29.6 ± 1.6	1 ± 2	-75.1
1.3.21.01.	P pilus usher PapC translocation domain	2vqi	Escherichia coli	Bact. Gram-neg outer	1	24	23.1 ± 1.0	3 ± 0	-61.0
1.2.20.01.	Mycobacterial protein Rv1761c	2k3m	Mycobacterium tuberculosis	Bact. Gram-pos plas.	1	1	23.8 ± 2.1	11 ± 3	-10.2
1.1.25.02.	Lactose Permease, structure at acidic pH	2cfp	Escherichia coli	Bact. Gram-neg inner	1	12	31.1 ± 1.4	2 ± 2	-85.4
1.1.01.02.	Adenosine receptor A2a, complex with antibody	3vga	Homo sapiens	Eukaryo. plasma	1	7	30.4 ± 1.4	7 ± 2	-62.8
1.3.21.01.	Outer membrane usher protein FimD, complex with FimC-FimF-FimG-FimH	4j3o	Escherichia coli	Bact. Gram-neg outer	1	24	23.8 ± 1.4	1 ± 1	-52.9
1.1.01.02.	Nociceptin receptor	4ea3	Homo sapiens	Eukaryo. plasma	1	7	32.0 ± 1.2	7 ± 1	-65.6
1.3.15.01.	Outer membrane protein G (OMPG), open state 1	2iwv	Escherichia coli	Bact. Gram-neg outer	1	14	25.3 ± 1.4	3 ± 5	-61.3
1.1.71.01.	SidF, inhibitor of growth family, member 3	4fyg	Legionella pneumophila	Vacuole	1	0	8.1 ± 3.3	81 ± 10	-3.9
1.2.44.01.	Amyloid beta A4 protein, peptide 686-726	2llm	Homo sapiens	Eukaryo. plasma	1	1	32.8 ± 2.2	30 ± 0	-30.8
1.1.35.01.	Sodium/proton antiporter 1 (NhaA)	1zcd	Escherichia coli	Bact. Gram-neg inner	1	14	28.4 ± 1.4	2 ± 2	-78.6
1.1.01.02.	5-hydroxytryptamine receptor 1B, conformation 2	4iaq	Homo sapiens	Eukaryo. plasma	1	7	34.4 ± 1.7	6 ± 1	-77.4
1.3.10.01.	Acidic sugar-specific porin NanC	2wjr	Escherichia coli	Bact. Gram-neg outer	1	12	23.3 ± 1.5	4 ± 4	-47.5
1.2.22.01.	Apoptosis regulator Bcl-2	1g5m	Homo sapiens	Mitochon. outer	1	0	4.2 ± 1.4	33 ± 11	-6.6
1.1.34.01.	Mitochondrial ADP-ATP carrier	1okc	Bos taurus	Mitochon. inner	1	6	29.5 ± 1.7	14 ± 1	-44.6
1.1.73.01.	TrbI protein	2bhv	Helicobacter pylori	Bact. Gram-neg outer	1	0	3.1 ± 1.3	42 ± 11	-6.4
1.2.33.02.	Monoamine oxidase A	2z5x	Homo sapiens	Mitochon. outer	1	1	31.0 ± 2.1	17 ± 1	-21.4
1.3.21.01.	Outer membrane usher protein FimD, complex with FimC-FimH	3rfz	Escherichia coli	Bact. Gram-neg outer	1	24	23.8 ± 0.8	5 ± 0	-65.1
1.1.44.01.	Disulfide bond formation protein B, conformation 1	2k74	Escherichia coli	Bact. Gram-neg inner	1	4	29.7 ± 2.4	26 ± 1	-50.2
1.1.67.01.	Transmembrane protein 14C	2los	Homo sapiens	Mitochon. inner	1	3	26.8 ± 0.4	0 ± 2	-18.5
1.3.19.01.	Cis-aconitate porin OpdH	2y0l	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	21.4 ± 1.5	6 ± 1	-57.2
1.2.16.01.	Pulmonary surfactant-associated protein C	1spf	Sus scrofa	Secreted	1	1	31.7 ± 3.3	21 ± 0	-32.0
1.3.11.02.	Invasin	4e1t	Yersinia pseudotuberculosis	Bact. Gram-neg outer	1	12	25.6 ± 1.4	9 ± 1	-51.0
1.1.56.01.	Steryl-sulfatase	1p49	Homo sapiens	Endoplasm. reticulum	1	2	29.6 ± 1.1	23 ± 0	-34.6
1.3.20.01.	Fe-regulated protein B, different variant	4aiq	Neisseria meningitidis	Bact. Gram-neg outer	1	22	23.6 ± 0.9	6 ± 0	-69.7
1.3.01.01.	Transmembrane beta-barrel platform protein	2jmm	Designed proteins	Undefined	1	8	23.9 ± 1.3	4 ± 4	-32.3
1.2.32.01.	Cytochrome P450 3A4, conformation 1	1tqn	Homo sapiens	Endoplasm. reticulum	1	0	8.7 ± 1.0	67 ± 11	-18.5
1.3.14.01.	Fatty Acid Transporter FadL, delS3, open channel	2r88	Escherichia coli	Bact. Gram-neg outer	1	14	24.0 ± 1.4	6 ± 2	-53.8
1.1.47.01.	Aerobic respiration control sensor protein acrB	2ksd	Escherichia coli	Bact. Gram-neg inner	1	2	27.9 ± 2.8	9 ± 1	-33.6
1.2.32.01.	Cytochrome P450 2B4, open state 2	1po5	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	3.5 ± 1.4	79 ± 9	-7.2
1.2.32.01.	Cytochrome P450 2C9, different conformation	1r9o	Homo sapiens	Endoplasm. reticulum	1	0	4.0 ± 1.1	59 ± 8	-10.1
1.1.09.01.	Calcium ATPase, E2-Pi state, conformation 3	3b9b	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.9 ± 1.6	16 ± 2	-58.1
1.2.25.02.	Na,K-ATPase regulatory protein FXYD1 (phospholemman)	2jp3	Rattus norvegicus	Endoplasm. reticulum	1	1	31.8 ± 3.2	18 ± 7	-20.2
1.2.17.02.	Synaptobrevin homolog 1	1iou	Saccharomyces cerevisiae	Eukaryo. plasma	1	0	3.4 ± 1.1	79 ± 12	-6.0
1.2.25.01.	Phosholamban	1fjk	Sus scrofa	Endoplasm. reticulum	1	1	30.1 ± 3.2	38 ± 6	-28.3
1.1.01.02.	Melanocortin-4 receptor model (active state) with agonist NDP-MSH	2iqr	Homo sapiens	Eukaryo. plasma	1	7	33.5 ± 2.0	24 ± 0	-60.6
1.1.48.01.	Putative sulfate permease CysZ	3tx3	Idiomarina loihiensis	Bact. Gram-neg inner	1	6	29.8 ± 0.6	17 ± 4	-49.5
1.2.32.01.	Steroid 17-alpha-hydroxylase/17,20 lyase (P450 17A1)	3swz	Homo sapiens	Endoplasm. reticulum	1	0	4.2 ± 1.6	56 ± 3	-8.4
1.1.09.01.	Plasma membrane ATPase 2, E1-ATP state	3b8c	Arabidopsis thaliana	Eukaryo. plasma	1	10	29.5 ± 1.5	9 ± 0	-56.8
1.2.12.01.	Fimbrial protein	3sok	Dichelobacter nodosus (Bacteroides nodosus)	Bact. Gram-neg inner	1	1	29.8 ± 3.9	18 ± 5	-25.0
1.2.32.01.	Cytochrome P450 2B6, different conformation	3ua5	Homo sapiens	Endoplasm. reticulum	1	0	4.7 ± 1.1	55 ± 3	-12.9
1.1.09.01.	Calcium ATPase, E2 state (Ca-free), conformation 5	1kju	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	33.8 ± 0.2	26 ± 1	-68.6
1.2.03.01.	T-cell surface glycoprotein CD4	2klu	Homo sapiens	Eukaryo. plasma	1	1	31.8 ± 2.6	12 ± 7	-23.7
1.1.09.01.	Calcium ATPase, E1-2Ca state, conformation 3	1su4	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.0 ± 2.7	26 ± 1	-68.6
1.1.15.01.	Glycine receptor, alpha1 subunit	1vry	Homo sapiens	Eukaryo. plasma	1	2	23.2 ± 3.7	5 ± 9	-25.3
1.1.01.02.	Beta-1 adrenergic receptor, inactive, complex with agonist	2y02	Meleagris gallopavo	Eukaryo. plasma	1	7	31.4 ± 1.3	2 ± 0	-76.9
1.2.03.02.	T-cell immunoglobulin and mucin domain-containing protein 2	2or7	Mus musculus	Eukaryo. plasma	1	0	0.9 ± 0.7	54 ± 6	-3.3
1.1.57.01.	Peptidase A24B, FlaK domain protein	3s0x	Methanococcus maripaludis	Archaebac.	1	6	31.8 ± 1.6	40 ± 2	-67.7
1.2.30.01.	Potassium voltage-gated channel subfamily E member 1	2k21	Homo sapiens	Eukaryo. plasma	1	1	12.1 ± 0.4	54 ± 2	-24.7
1.2.38.01.	Penicillin-binding protein 2	2olv	Staphylococcus aureus	Bact. Gram-pos plas.	1	0	3.7 ± 2.0	58 ± 8	-7.3
1.3.02.01.	Outer membrane protein NspA	1p4t	Neisseria meningitidis	Bact. Gram-neg outer	1	8	24.9 ± 2.4	22 ± 3	-42.9
1.1.75.02.	Sec-independent protein translocase TatA	2l16	Bacillus subtilis	Bact. Gram-pos plas.	1	1	27.6 ± 2.9	10 ± 1	-27.9
1.2.01.01.	Receptor tyrosine-protein kinase erbB-2	1n8y	Rattus norvegicus	Eukaryo. plasma	1	0	3.4 ± 3.0	53 ± 5	-4.2
1.3.20.01.	Ferric enterobactin receptor FepA	1fep	Escherichia coli	Bact. Gram-neg outer	1	22	24.3 ± 1.1	1 ± 0	-77.2
1.2.03.04.	Leukocyte immunoglobulin-like receptor subfamily B member 4	3p2t	Homo sapiens	Eukaryo. plasma	1	0	1.7 ± 0.4	84 ± 5	-5.9
1.3.07.01.	Outer membrane protease OmpT	1i78	Escherichia coli	Bact. Gram-neg outer	1	10	26.5 ± 1.6	5 ± 6	-46.9
1.1.25.01.	Glycerol-3-Phosphate Transporter	1pw4	Escherichia coli	Bact. Gram-neg inner	1	12	31.2 ± 1.4	1 ± 7	-92.5
1.3.20.01.	Outer membrane transporter FecA, different conformation	1kmp	Escherichia coli	Bact. Gram-neg outer	1	22	24.9 ± 0.9	4 ± 0	-74.0
1.3.15.01.	Outer membrane protein G (OMPG), closed state	2iww	Escherichia coli	Bact. Gram-neg outer	1	14	24.7 ± 1.4	6 ± 4	-63.3
1.2.17.02.	Synaptobrevin homolog YKT6	3kyq	Rattus norvegicus	Vesicle	1	0	2.5 ± 2.0	53 ± 8	-4.9
1.1.01.01.	Sensory Rhodopsin	1xio	Anabaena sp.	Bact. Gram-neg inner	1	7	31.9 ± 1.5	13 ± 4	-63.1
1.3.17.01.	Filamentous hemagglutinin transporter FhaC	2qdz	Bordetella pertussis	Bact. Gram-neg outer	1	16	24.4 ± 1.1	7 ± 7	-69.1
1.1.01.02.	Thrombin (proteinase-activated) receptor 1, PAR1	3vw7	Homo sapiens	Eukaryo. plasma	1	7	33.4 ± 1.9	1 ± 0	-72.2
1.3.14.01.	FadL homologue	3dwo	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	14	24.8 ± 1.6	6 ± 3	-54.7
1.1.08.01.	ATP synthase subunit b	1b9u	Escherichia coli	Bact. Gram-neg inner	1	1	29.8 ± 4.0	41 ± 2	-23.1
1.1.01.02.	Rhodopsin, inactive, conformation 3	1u19	Bos taurus	Eukaryo. plasma	1	7	31.2 ± 1.5	12 ± 1	-71.9
1.3.19.01.	BenF-like porin	3jty	Pseudomonas fluorescens	Bact. Gram-neg outer	1	18	24.2 ± 1.2	1 ± 0	-59.8
1.3.12.01.	Outer membrane phospholipase A, monomer	1qd5	Escherichia coli	Bact. Gram-neg outer	1	12	24.6 ± 1.2	6 ± 0	-52.6
1.3.22.01.	VDAC-1 channel, NMR model	2k4t	Homo sapiens	Mitochon. outer	1	19	22.0 ± 1.5	1 ± 1	-34.8
1.2.32.01.	Cholesterol side-chain cleavage enzyme (P450 11A1), complex with adrenodoxin	3n9y	Homo sapiens	Mitochon. inner	1	0	4.1 ± 0.6	49 ± 5	-6.2
1.2.22.01.	Bcl-2-like protein 1, complex with alpha-beta-foldamer	4a1u	Homo sapiens	Mitochon. outer	1	0	5.8 ± 0.3	26 ± 5	-5.7
1.3.19.01.	Histidine porin OpdC	3sy9	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.4 ± 0.8	5 ± 0	-63.2
1.2.11.02.	Capsid protein G8P, monomer	2xkm	Bacteriophage Pf1	Secreted	1	1	29.2 ± 4.6	34 ± 1	-23.0
1.3.20.01.	Pesticin receptor FyuA	4epa	Yersinia pestis	Bact. Gram-neg outer	1	22	23.6 ± 0.8	3 ± 0	-73.5
1.3.25.02.	Hemolysin	1xez	Vibrio cholerae	Secreted	1	0	8.2 ± 2.3	19 ± 6	-6.0
1.3.19.02.	Alginate export protein, AlgE, different conformation of loops	4afk	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	24.8 ± 0.9	3 ± 0	-73.0
1.2.32.01.	Cytochrome P450 2A6	1z10	Homo sapiens	Endoplasm. reticulum	1	0	5.0 ± 1.7	44 ± 18	-9.5
1.1.47.01.	Sensor protein qseC	2kse	Escherichia coli	Bact. Gram-neg inner	1	2	31.3 ± 2.5	19 ± 0	-35.7
1.1.25.04.	L-fucose-proton symporter	3o7q	Escherichia coli	Bact. Gram-neg inner	1	12	30.7 ± 1.3	6 ± 0	-85.3
1.2.32.01.	Cytochrome P450 2C5, different conformation	1dt6	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	7.3 ± 1.0	13 ± 7	-8.8
1.1.25.05.	Bacterial oligopeptide-proton symporter	2xut	Shewanella oneidensis	Bact. Gram-neg inner	1	14	30.9 ± 1.4	10 ± 0	-102.5
1.2.32.01.	Cytochrome P450 2E1	3e6i	Homo sapiens	Endoplasm. reticulum	1	0	8.3 ± 2.0	49 ± 8	-14.2
1.2.04.01.	Integrin alpha-IIb, transmembrane helix	2k1a	Homo sapiens	Eukaryo. plasma	1	1	34.4 ± 2.6	17 ± 6	-36.9
1.2.32.01.	Sterol 14-alpha-demethylase (CYP51)	3g1q	Trypanosoma brucei	Endoplasm. reticulum	1	0	8.1 ± 1.5	62 ± 12	-10.8
1.1.25.06.	Phosphate transporter	4j05	Acanthamoeba culbertsoni	Eukaryo. plasma	1	12	30.0 ± 0.5	14 ± 0	-84.2
1.1.33.02.	Bile acid sodium symporter ASBT	3zuy	Neisseria meningitidis	Bact. Gram-neg inner	1	10	29.8 ± 1.5	15 ± 2	-82.3
1.2.25.01.	Phospholamban	1n7l	Oryctolagus cuniculus	Endoplasm. reticulum	1	1	29.8 ± 3.6	34 ± 12	-32.3
1.1.01.02.	Melanocortin-4 receptor model (inactive state) with antagonist AGRP	2iqv	Homo sapiens	Eukaryo. plasma	1	7	31.9 ± 1.1	19 ± 0	-49.1
1.2.32.01.	Steroid 21-hydroxylase (P450 C21)	3qz1	Bos taurus	Endoplasm. reticulum	1	0	5.9 ± 1.6	72 ± 3	-10.4
1.1.49.01.	ATP-dependent zinc metalloprotease FtsH	1lv7	Escherichia coli	Bact. Gram-neg inner	1	0	2.1 ± 1.0	80 ± 11	-4.3
1.1.70.01.	CaaX Protease Ste24p	4il3	Saccharomyces mikatae	Endoplasm. reticulum	1	7	29.8 ± 1.4	8 ± 0	-63.3
1.1.09.01.	Calcium ATPase, E2 state (Ca-free), conformation 6	2zbe	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	28.0 ± 0.7	16 ± 0	-55.4
1.1.25.06.	D-xylose-proton symporter, conformation 1	4gc0	Escherichia coli	Bact. Gram-neg inner	1	12	30.2 ± 0.9	1 ± 0	-90.2
1.1.09.01.	Calcium ATPase, E1-2Ca state, conformation 4	2c9m	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.8 ± 1.2	27 ± 1	-54.3
1.1.01.02.	Squid rhodopsin, inactive, complex with inverse agonist 11-cis retinal	2ziy	Todarodes pacificus	Eukaryo. plasma	1	7	32.9 ± 1.7	11 ± 2	-75.1
1.1.01.02.	Rhodopsin, inactive, conformation 2	3oax	Bos taurus	Eukaryo. plasma	1	7	30.9 ± 1.4	11 ± 0	-73.6
1.1.44.01.	Disulfide bond formation protein B, conformation 2	2ltq	Escherichia coli	Bact. Gram-neg inner	1	4	28.4 ± 1.5	26 ± 0	-36.5
1.1.25.02.	Lactose permease, conformation 3	1pv6	Escherichia coli	Bact. Gram-neg inner	1	12	31.8 ± 1.2	5 ± 0	-89.1
1.1.01.01.	Sensory rhodopsin II, monomer	1h68	Natronomonas pharaonis	Archaebac.	1	7	30.3 ± 1.5	15 ± 2	-60.0
1.2.03.02.	Hepatitis A virus cellular receptor 1 homolog	2or8	Mus musculus	Eukaryo. plasma	1	0	4.2 ± 2.4	51 ± 16	-3.9
1.1.44.01.	DsbB - DsbA complex, conformation 4	3e9j	Escherichia coli	Bact. Gram-neg inner	1	4	26.8 ± 1.5	31 ± 1	-27.1
1.1.39.02.	Thiamine transporter protein	3rlb	Lactococcus lactis	Bact. Gram-pos plas.	1	6	30.8 ± 1.8	9 ± 1	-60.4
1.1.38.01.	H+-driven MATE exporter, outward-open, straight conformation	3vvq	Pyrococcus furiosus	Archaebac.	1	12	31.8 ± 1.3	8 ± 0	-87.2
1.2.01.01.	Receptor tyrosine kinase erbB-2	1iij	Rattus norvegicus	Eukaryo. plasma	1	1	31.8 ± 2.8	27 ± 2	-31.8
1.2.38.01.	Glycosyltransferase MtgA	3hzs	Staphylococcus aureus	Bact. Gram-pos plas.	1	0	7.0 ± 1.1	54 ± 9	-14.6
1.3.07.01.	Plasminogen activator PLA (coagulase/fibrinolysin)	2x55	Yersinia pestis	Bact. Gram-neg outer	1	10	25.6 ± 1.9	4 ± 5	-43.9
1.1.39.01.	Riboflavin transporter RibU	3p5n	Staphylococcus aureus	Bact. Gram-pos plas.	1	6	30.6 ± 1.4	6 ± 4	-53.5
1.1.15.01.	Nicotinic acetylcholine receptor, beta2 subunit, in LDAO micelles	2lm2	Homo sapiens	Eukaryo. plasma	1	4	29.2 ± 1.6	14 ± 2	-48.8
1.2.32.01.	Fatty-acid peroxygenase	1izo	Bacillus subtilis	Bact. Gram-pos plas.	1	0	1.2 ± 0.3	76 ± 1	-5.5
1.3.20.01.	Outer membrane transporter FecA	1kmo	Escherichia coli	Bact. Gram-neg outer	1	22	24.5 ± 1.2	3 ± 0	-69.6
1.1.07.01.	Nitric oxide reductase	3ayf	Bacillus stearothermophilus	Bact. Gram-pos plas.	1	14	31.6 ± 0.8	8 ± 0	-109.3
1.3.20.01.	Fe(III)-pyochelin receptor FptA	1xkw	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	22	24.8 ± 1.0	5 ± 4	-84.3
1.3.11.01.	Autotransporter NalP, different conformation	1uyo	Neisseria meningitidis	Bact. Gram-neg outer	1	12	23.6 ± 1.4	8 ± 0	-42.7
1.2.39.03.	Disintegrin and metalloproteinase domain-containing protein 10	2ao7	Bos taurus	Golgi	1	0	3.1 ± 1.4	81 ± 6	-5.7
1.1.01.02.	Opioid delta receptor	4ej4	Mus musculus	Eukaryo. plasma	1	7	34.4 ± 0.8	11 ± 6	-73.2
1.1.01.02.	Adenosine receptor A2a, inactive state, with annular lipids	4eiy	Homo sapiens	Eukaryo. plasma	1	7	32.2 ± 1.2	18 ± 0	-70.4
1.3.19.01.	Outer membrane porin OprD	2odj	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.0 ± 0.8	8 ± 0	-63.1
1.3.06.01.	Major outer membrane protein from Thermus thermophilus	3dzm	Thermus thermophilus	Bact. Gram-neg outer	1	8	28.5 ± 2.6	6 ± 10	-50.3
1.2.43.06.	Spike glycoprotein	2ghv	Human SARS coronavirus	Viral	1	0	3.8 ± 1.9	45 ± 9	-6.8
1.1.25.02.	Lactose permease, conformation 1	2cfq	Escherichia coli	Bact. Gram-neg inner	1	12	31.9 ± 1.1	5 ± 1	-87.9
1.3.20.01.	Outer membrane cobalamin transporter BtuB, complex with colicin E2 R-domain	2ysu	Escherichia coli	Bact. Gram-neg outer	1	22	24.2 ± 1.0	5 ± 0	-75.2
1.1.60.01.	Protease GlpG	2nr9	Haemophilus influenzae	Bact. Gram-neg inner	1	6	28.2 ± 1.6	13 ± 3	-52.0
1.3.20.01.	Outer membrane cobalamin transporter BtuB, with cyanocobalamin	3m8d	Escherichia coli	Bact. Gram-neg outer	1	22	23.3 ± 0.8	6 ± 1	-70.5
1.3.22.01.	VDAC-1 channel	2jk4	Homo sapiens	Mitochon. outer	1	19	23.4 ± 2.3	0 ± 1	-40.0
1.2.32.01.	Cholesterol side-chain cleavage enzyme (P450 11A1)	3mzs	Bos taurus	Mitochon. inner	1	0	3.2 ± 0.3	33 ± 1	-6.7
1.3.11.01.	Serine protease EspP, pre-cleavage structure	3slj	Escherichia coli	Bact. Gram-neg outer	1	12	25.4 ± 1.2	6 ± 1	-53.1
1.1.01.01.	Xanthorhodopsin	3ddl	Salinibacter ruber	Bact. Gram-neg inner	1	7	28.2 ± 1.8	11 ± 0	-60.7
1.3.19.01.	Glycine-glutamate dipeptide porin OpdP	3syb	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.6 ± 0.9	8 ± 0	-62.0
1.1.44.01.	DsbB - DsbA complex, conformation 2	2zup	Escherichia coli	Bact. Gram-neg inner	1	4	24.2 ± 2.9	3 ± 8	-18.3
1.1.34.01.	Mitochondrial ADP-ATP carrier, with carboxyatractyloside	2c3e	Bos taurus	Mitochon. inner	1	6	30.0 ± 1.0	4 ± 2	-44.0
1.1.09.01.	Calcium ATPase, E2 state (Ca-free), conformation 1	2agv	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.7 ± 2.2	20 ± 2	-61.5
1.3.01.01.	Outer membrane protein A (OMPA)	1bxw	Escherichia coli	Bact. Gram-neg outer	1	8	25.4 ± 1.9	5 ± 1	-35.6
1.1.68.01.	Transmembrane protein 141	2lor	Homo sapiens	Undefined	1	2	24.4 ± 4.0	21 ± 0	-22.2
1.2.32.01.	Sterol 14-alpha-demethylase (CYP51), conformation 2	2wx2	Trypanosoma cruzi	Endoplasm. reticulum	1	0	5.9 ± 5.9	63 ± 2	-6.2
1.2.32.01.	Cytochrome P450 2R1	3czh	Homo sapiens	Endoplasm. reticulum	1	0	8.3 ± 1.5	48 ± 13	-13.2
1.2.04.01.	Integrin beta-3, transmembrane helix	2rmz	Homo sapiens	Eukaryo. plasma	1	1	30.0 ± 3.6	49 ± 2	-36.0
1.1.60.01.	Protease GlpG, conformation 1	2xtv	Escherichia coli	Bact. Gram-neg inner	1	6	28.8 ± 1.6	14 ± 1	-61.1
1.2.32.01.	Sterol 14-alpha-demethylase (CYP51), conformation 1	2wuz	Trypanosoma cruzi	Endoplasm. reticulum	1	0	4.0 ± 1.1	75 ± 11	-9.9
1.2.13.01.	Intrinsic membrane protein PufX	2ita	Rhodobacter sphaeroides	Bact. Gram-neg inner	1	1	32.2 ± 5.1	33 ± 1	-22.8
1.2.32.01.	Cytochrome P450 2B6	3ibd	Homo sapiens	Endoplasm. reticulum	1	0	4.7 ± 1.0	57 ± 3	-10.8
1.2.07.01.	Protein spitz	3ca7	Drosophila melanogaster	Endoplasm. reticulum	1	0	3.3 ± 2.8	87 ± 3	-4.3
1.2.32.01.	Cytochrome P450 1A1	4i8v	Homo sapiens	Endoplasm. reticulum	1	0	7.1 ± 1.0	64 ± 3	-15.1
1.1.01.02.	TM1-TM2 fragment of fungal STE2 receptor	2k9p	Saccharomyces cerevisiae	Eukaryo. plasma	1	2	29.8 ± 3.1	21 ± 4	-10.5
1.1.09.01.	Calcium ATPase, E2 state (Ca-free), conformation 8	2zbg	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.0 ± 1.7	21 ± 0	-66.5
1.2.32.01.	Sterol 14-alpha-demethylase (CYP51), conformation 3	3ksw	Trypanosoma cruzi	Endoplasm. reticulum	1	0	8.0 ± 6.7	61 ± 6	-9.1
1.1.01.02.	Beta-2 adrenergic receptor, active state, complex with antibody	3p0g	Homo sapiens	Eukaryo. plasma	1	7	30.1 ± 1.4	9 ± 1	-62.9
1.1.12.01.	Potassium channel KvAP, sensor domain	1ors	Aeropyrum pernix	Archaebac.	1	5	31.5 ± 2.2	19 ± 1	-50.3
1.1.01.02.	Adenosine receptor A2a, partially active state, engineered, complex with agonist	2ydv	Homo sapiens	Eukaryo. plasma	1	7	31.0 ± 1.3	10 ± 0	-61.4
1.1.25.02.	Lactose permease, conformation 4	2y5y	Escherichia coli	Bact. Gram-neg inner	1	12	31.8 ± 1.3	4 ± 1	-89.0
1.2.32.01.	Cytochrome P450 120a1	2ve4	Synechocystis sp.	Thylakoid	1	0	6.3 ± 0.9	47 ± 8	-8.6
1.1.01.01.	Bacteriorhodopsin, monomer	1py6	Halobacterium salinarum	Archaebac.	1	7	29.6 ± 2.2	24 ± 8	-59.7
1.2.04.01.	Integrin beta-3, cytoplasmic domain	1s4x	Homo sapiens	Eukaryo. plasma	1	0	6.9 ± 1.0	18 ± 10	-5.8
1.1.38.01.	H+-driven MATE exporter, outward-open, "bent" conformation	3vvo	Pyrococcus furiosus	Archaebac.	1	12	31.4 ± 1.1	11 ± 0	-93.1
1.2.24.01.	Protein Vpu, cytoplasmic domain, in DPC micelles	2k7y	Human immunodeficiency virus type 1	Eukaryo. plasma	1	0	4.5 ± 1.4	54 ± 17	-5.4
1.2.33.02.	Protoporphyrinogen oxidase	2ivd	Myxococcus xanthus	Bact. Gram-neg inner	1	0	3.7 ± 0.2	29 ± 2	-8.0
1.2.17.01.	Vesicle-associated membrane protein 2	2kog	Rattus norvegicus	Eukaryo. plasma	1	1	34.8 ± 1.7	27 ± 1	-33.7
1.3.08.01.	Outer membrane adhesin/invasin OpcA	1k24	Neisseria meningitidis	Bact. Gram-neg outer	1	10	25.4 ± 1.3	10 ± 11	-41.7
1.2.03.02.	Cytotoxic T-lymphocyte protein 4	1dqt	Mus musculus	Eukaryo. plasma	1	0	3.4 ± 1.6	64 ± 4	-5.3
1.3.20.01.	Outer membrane cobalamin transporter BtuB	1nqe	Escherichia coli	Bact. Gram-neg outer	1	22	23.4 ± 1.0	5 ± 0	-68.8
1.2.38.01.	Monofunctional glycosyltransferase	3vmr	Staphylococcus aureus	Bact. Gram-pos plas.	1	1	30.8 ± 1.2	25 ± 2	-35.4
1.2.04.01.	Integrin alpha-1	2l8s	Homo sapiens	Eukaryo. plasma	1	1	32.0 ± 3.7	40 ± 1	-34.5
1.1.01.02.	Sphingosine 1-phosphate receptor 1	3v2y	Homo sapiens	Eukaryo. plasma	1	7	32.2 ± 1.4	10 ± 0	-65.9
1.3.05.01.	Lipid A deacylase PagL	2erv	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	8	24.7 ± 1.8	20 ± 2	-41.1
1.2.41.01.	Acyl-CoA-binding protein	2cb8	Homo sapiens	Peroxisome	1	0	2.7 ± 2.0	74 ± 29	-5.2
1.1.08.01.	F1F0 ATP synthase subunit c	1a91	Escherichia coli	Bact. Gram-neg inner	1	2	36.1 ± 6.7	21 ± 3	-21.4
1.3.11.01.	Serine protease EspP, post-cleavage structure	2qom	Escherichia coli	Bact. Gram-neg outer	1	12	25.1 ± 1.6	6 ± 7	-55.9
1.2.12.01.	Fimbrial protein, type IV pilin, monomer	2pil	Neisseria gonorrhoeae	Bact. Gram-neg inner	1	1	30.8 ± 5.7	21 ± 5	-24.9
1.3.01.01.	Outer membrane protein A from Klebsiella	2k0l	Klebsiella pneumoniae	Bact. Gram-neg outer	1	8	24.3 ± 2.3	18 ± 6	-26.8
1.1.63.01.	Type 1 signal peptidase, complex with lipopeptide inhibitor	1t7d	Escherichia coli	Bact. Gram-neg inner	1	0	3.9 ± 1.0	65 ± 11	-7.6
1.3.20.01.	Outer membrane cobalamin transporter BtuB, complex with colicin E3 R-domain	1ujw	Escherichia coli	Bact. Gram-neg outer	1	22	23.6 ± 1.1	5 ± 0	-71.5
1.2.40.01.	Mitochondria fission protein Fis1	1nzn	Homo sapiens	Mitochon. outer	1	0	6.1 ± 1.4	72 ± 8	-9.3
1.3.15.01.	Outer membrane protein G (OMPG), open state 2	2x9k	Escherichia coli	Bact. Gram-neg outer	1	14	24.7 ± 1.2	5 ± 2	-62.7
1.3.22.01.	VDAC-1 channel	3emn	Mus musculus	Mitochon. outer	1	19	23.4 ± 1.1	5 ± 1	-52.5
1.3.01.02.	Attachment invasion locus protein	3qra	Yersinia pestis	Bact. Gram-neg outer	1	8	25.2 ± 1.4	14 ± 7	-32.2
1.3.19.01.	Porin OpdF	3szd	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	22.0 ± 1.6	3 ± 0	-60.3
1.1.44.01.	Disulfide bond formation protein B, conformation 3	2zuq	Escherichia coli	Bact. Gram-neg inner	1	4	27.9 ± 3.1	27 ± 1	-36.6
1.2.25.02.	Na,K-ATPase regulatory protein FXYD1 (phospholemman)	2jo1	Homo sapiens	Endoplasm. reticulum	1	1	30.6 ± 2.5	11 ± 4	-27.8
1.3.25.01.	Gamma-hemolysin, component B	3lkf	Staphylococcus aureus	Secreted	1	0	1.7 ± 2.5	51 ± 11	-4.5
1.1.30.01.	Membrane protein insertase YidC, periplasmic domain	3blc	Escherichia coli	Bact. Gram-neg inner	1	0	6.6 ± 0.5	40 ± 11	-7.0
1.2.25.01.	Sarcolipin	1jdm	Homo sapiens	Endoplasm. reticulum	1	1	29.6 ± 2.4	3 ± 7	-28.5
1.3.04.03.	Lipid A acylase PagP, different conformation of loops	1thq	Escherichia coli	Bact. Gram-neg outer	1	8	23.4 ± 2.5	27 ± 3	-31.3
1.2.25.01.	Phospholamban, monomer	2kb7	Homo sapiens	Endoplasm. reticulum	1	1	32.0 ± 2.2	15 ± 2	-34.6
1.1.09.01.	Calcium ATPase, E2-Pi state, conformation 2	3ar8	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	28.6 ± 1.8	19 ± 0	-60.6
1.2.25.01.	Phospholamban, cytoplasmic helix	1plp	Homo sapiens	Endoplasm. reticulum	1	0	4.0 ± 1.3	80 ± 4	-7.2
1.2.32.01.	Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 1	2q9f	Homo sapiens	Endoplasm. reticulum	1	0	2.8 ± 1.0	86 ± 7	-5.8
1.1.28.03.	SecDF protein-export membrane protein	3aqp	Thermus thermophilus	Bact. Gram-neg inner	1	12	29.8 ± 0.9	5 ± 1	-93.8
1.2.32.01.	Sterol 14-alpha-demethylase (CYP51)	3l4d	Leishmania infantum	Endoplasm. reticulum	1	0	8.4 ± 1.8	66 ± 9	-12.6
1.1.01.02.	Adenosine receptor A2a, inactive state, engineered, complex with inverse agonist	3pwh	Homo sapiens	Eukaryo. plasma	1	7	31.0 ± 1.3	9 ± 0	-67.3
1.1.03.01.	Light-harvesting protein B-870, beta chain	1wrg	Rhodospirillum rubrum	Bact. Gram-neg inner	1	1	27.0 ± 4.7	44 ± 1	-23.9
1.2.32.01.	Cholesterol 7-alpha-monooxygenase (P450 7A1)	3dax	Homo sapiens	Endoplasm. reticulum	1	0	1.8 ± 1.9	69 ± 8	-3.9
1.1.26.01.	Leucine transporter LeuT, inward-facing conformation	3tt3	Aquifex aeolicus	Bact. Gram-neg inner	1	12	27.4 ± 1.6	9 ± 0	-89.1
1.2.32.01.	Cytochrome P450 2D6, conformation 3	3qm4	Homo sapiens	Endoplasm. reticulum	1	0	9.0 ± 1.4	35 ± 11	-9.3
1.1.09.01.	Calcium ATPase, E2-Pi state, conformation 4	3b9r	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	26.8 ± 0.0	25 ± 0	-44.1
1.2.32.01.	Cytochrome P450 2B4, closed state 2	2q6n	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	5.5 ± 0.4	55 ± 2	-13.0
1.1.01.02.	C-X-C chemokine receptor type 4, inactive, complex with antagonist	3oe6	Homo sapiens	Eukaryo. plasma	1	7	35.3 ± 2.5	8 ± 7	-79.7
1.1.01.02.	Rhodopsin, active (metarhodopsin II), complex with peptide of transducin	3pqr	Bos taurus	Eukaryo. plasma	1	7	31.8 ± 1.1	9 ± 1	-78.3
1.2.04.01.	Integrin beta-3, cytoplasmic domain, monophosphorylated (747pY)	2ljd	Homo sapiens	Eukaryo. plasma	1	0	8.1 ± 0.6	44 ± 4	-7.6
1.1.60.01.	Protease GlpG, complex with inhibitor, conformation 3	3ubb	Escherichia coli	Bact. Gram-neg inner	1	6	29.8 ± 1.3	21 ± 1	-65.3
1.1.38.01.	H+-driven MATE exporter, outward-open, with nonpeptide inhibitor	3vvp	Pyrococcus furiosus	Archaebac.	1	12	29.8 ± 1.3	8 ± 0	-79.6
1.2.24.01.	Protein Vpu, cytoplasmic domain, structure in aqueous solution	1vpu	Human immunodeficiency virus type 1	Eukaryo. plasma	1	0	7.4 ± 2.1	64 ± 5	-5.6
1.1.25.07.	Nitrite exporter	4iu9	Escherichia coli	Bact. Gram-neg inner	1	12	31.0 ± 1.2	4 ± 0	-88.1
1.1.26.02.	Sodium-hydantoin transporter Mhp1, ligand-bound	2jlo	Mycobacterium liquefaciens	Bact. Gram-pos plas.	1	12	31.2 ± 0.8	15 ± 0	-96.5
1.1.58.01.	Site-2 protease (S2P) metalloprotease	3b4r	Methanococcus jannaschii	Archaebac.	1	6	29.9 ± 1.4	23 ± 0	-65.0
1.3.11.01.	Autotransporter NalP	1uyn	Neisseria meningitidis	Bact. Gram-neg outer	1	12	25.3 ± 1.3	8 ± 8	-47.6
1.3.20.01.	Pyoverdine Outer Membrane Receptor FpvA	2iah	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	22	24.0 ± 0.5	8 ± 0	-79.7
1.1.01.02.	Beta-2 adrenergic receptor, inactive state	4gbr	Homo sapiens	Eukaryo. plasma	1	7	31.6 ± 1.3	7 ± 1	-71.7
1.3.03.01.	Outer membrane protein W	2f1v	Escherichia coli	Bact. Gram-neg outer	1	8	25.4 ± 1.4	10 ± 3	-38.3
1.1.01.02.	Muscarinic acetylcholine receptor M3	4daj	Rattus norvegicus	Eukaryo. plasma	1	7	32.2 ± 1.2	5 ± 0	-75.8
1.3.02.01.	Outer membrane protein H (OprH)	2lhf	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	8	20.6 ± 0.6	15 ± 3	-16.4
1.2.41.01.	Acyl-CoA-binding domain-containing protein 4	2wh5	Homo sapiens	Peroxisome	1	0	7.2 ± 2.4	77 ± 26	-5.7
1.1.69.01.	HIG1 domain family member 1A	2lom	Homo sapiens	Eukaryo. plasma	1	2	22.0 ± 5.0	1 ± 1	-27.3
1.1.10.04.	Multidrug resistance protein pgp-1	4f4c	Caenorhabditis elegans	Eukaryo. plasma	1	14	32.0 ± 1.8	6 ± 0	-105.1
1.3.20.01.	Outer membrane cobalamin transporter BtuB, meso form	2guf	Escherichia coli	Bact. Gram-neg outer	1	22	23.4 ± 0.9	6 ± 7	-69.3
1.2.11.02.	Capsid protein G8P	2cps	Bacteriophage M13	Viral	1	1	30.8 ± 3.1	15 ± 3	-19.9
1.3.20.01.	Hemophore receptor HasR	3csl	Serratia marcescens	Bact. Gram-neg outer	1	22	25.4 ± 1.3	4 ± 5	-72.2
1.1.63.01.	Type 1 signal peptidase, complex with inhibitor	1b12	Escherichia coli	Bact. Gram-neg inner	1	0	5.4 ± 1.8	88 ± 7	-5.1
1.3.11.01.	Esterase EstA	3kvn	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	12	24.4 ± 1.5	4 ± 2	-48.7
1.1.44.01.	DsbB - DsbA complex, conformation 1	2hi7	Escherichia coli	Bact. Gram-neg inner	1	4	24.3 ± 3.0	30 ± 0	-34.9
1.2.33.02.	Protoporphyrinogen oxidase	1sez	Nicotiana tabacum	Mitochon. inner	1	0	2.2 ± 1.0	50 ± 3	-7.0
1.3.03.01.	Outer membrane protein OprG	2x27	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	8	23.9 ± 1.7	7 ± 3	-39.6
1.3.01.02.	Attachment invasion locus protein, complex with the heparin analogue	3qrc	Yersinia pestis	Bact. Gram-neg outer	1	8	24.6 ± 1.2	7 ± 5	-31.6
1.3.19.01.	Porin OpdQ	3t24	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.0 ± 1.3	2 ± 0	-56.5
1.1.09.01.	Calcium ATPase, E1-2Ca state, conformation 1	3ar2	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.6 ± 0.9	25 ± 0	-70.9
1.3.16.04.	Porin B, low pH structure	4gf4	Pseudomonas putida	Bact. Gram-neg outer	1	16	22.4 ± 1.1	5 ± 2	-54.3
1.3.25.01.	Leukocidin F	1pvl	Staphylococcus aureus	Secreted	1	0	4.0 ± 3.2	47 ± 10	-3.7
1.2.32.01.	Cytochrome P450 2C5	1nr6	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	10.6 ± 1.0	54 ± 18	-9.1
1.3.08.01.	Outer membrane adhesin/invasin OpcA, disordered loops	2vdf	Neisseria meningitidis	Bact. Gram-neg outer	1	10	24.8 ± 1.2	8 ± 0	-47.0
1.2.34.01.	Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4 (OST4)	1rkl	Saccharomyces cerevisiae	Endoplasm. reticulum	1	1	24.8 ± 3.2	22 ± 8	-18.4
1.3.17.01.	Filamentous hemagglutinin transporter FhaC, R450A, disordered loops	3njt	Bordetella pertussis	Bact. Gram-neg outer	1	16	23.6 ± 0.9	7 ± 0	-65.8
1.2.32.01.	Cholesterol 7-alpha-monooxygenase (P450 7A1), different conformation	3sn5	Homo sapiens	Endoplasm. reticulum	1	0	6.0 ± 1.9	73 ± 4	-6.5
1.1.60.01.	Protease GlpG, complex with inhibitor, conformation 1	2xow	Escherichia coli	Bact. Gram-neg inner	1	6	29.0 ± 1.7	15 ± 2	-59.0
1.1.03.01.	Light-harvesting complex LH1, alpha chain	1xrd	Rhodospirillum rubrum	Bact. Gram-neg inner	1	1	30.3 ± 3.1	30 ± 4	-30.5
1.1.01.01.	Proton-pumping rhodopsin-2 from algae	3am6	Acetabularia acetabulum	Eukaryo. plasma	1	7	31.2 ± 1.6	10 ± 1	-65.4
1.1.03.01.	Light-harvesting protein B-875, beta chain	1jo5	Rhodobacter sphaeroides	Bact. Gram-neg inner	1	1	29.6 ± 1.5	20 ± 2	-24.7
1.2.32.01.	Cytochrome P450 1B1	3pm0	Homo sapiens	Endoplasm. reticulum	1	0	3.8 ± 0.7	79 ± 1	-7.0
1.2.42.01.	Glideosome-associated protein 50	3tgh	Plasmodium falciparum	Endoplasm. reticulum	1	0	4.2 ± 3.4	69 ± 3	-4.3
1.1.01.02.	Adenosine receptor A2a, inactive state, complex with antagonist	3eml	Homo sapiens	Eukaryo. plasma	1	7	31.8 ± 1.2	8 ± 12	-66.1
1.1.09.01.	Calcium ATPase, E2-Pi state, conformation 5	3fpb	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	27.0 ± 2.3	23 ± 0	-64.9
1.2.32.01.	Cytochrome P450 2B4, closed state 3	3g5n	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	5.7 ± 1.8	65 ± 3	-12.1
1.1.01.02.	Beta-1 adrenergic receptor, inactive, complex with antagonist	2ycw	Meleagris gallopavo	Eukaryo. plasma	1	7	32.2 ± 1.3	2 ± 0	-77.8
1.1.01.01.	Archaerhodopsin-2	1vgo	Halobacterium sp.	Archaebac.	1	7	30.7 ± 1.3	18 ± 2	-73.1
1.2.04.01.	Integrin beta-3, cytoplasmic domain, biphosphorylated (747pY, 759pY)	2lje	Homo sapiens	Eukaryo. plasma	1	0	4.0 ± 0.5	74 ± 2	-7.0
1.1.60.01.	Protease GlpG, conformation 2	2nrf	Escherichia coli	Bact. Gram-neg inner	1	6	27.6 ± 1.5	13 ± 2	-45.9
1.1.25.06.	D-xylose-proton symporter, conformation 2	4ja3	Escherichia coli	Bact. Gram-neg inner	1	12	29.8 ± 1.0	4 ± 1	-87.6
1.1.26.02.	Sodium-hydantoin transporter Mhp1, inward-facing conformation	2x79	Mycobacterium liquefaciens	Bact. Gram-pos plas.	1	12	30.7 ± 1.1	13 ± 0	-85.0
1.1.26.05.	Amino acid transporter ApcT, inward-facing conformation	3gia	Methanococcus jannaschii	Archaebac.	1	12	29.9 ± 1.4	11 ± 2	-92.1
1.2.01.01.	Insulin-like growth factor 1 receptor	1p4o	Homo sapiens	Eukaryo. plasma	1	0	2.4 ± 1.0	37 ± 11	-5.1
1.1.53.01.	Integral Membrane Methyltransferase	4a2n	Methanosarcina acetivorans	Archaebac.	1	5	30.6 ± 1.2	10 ± 2	-58.3
1.2.03.02.	T-cell-specific surface glycoprotein CD28	1yjd	Homo sapiens	Eukaryo. plasma	1	0	4.5 ± 0.6	46 ± 11	-3.6
1.2.18.01.	Sortase B	1rz2	Bacillus anthracis	Bact. Gram-pos plas.	1	0	3.0 ± 0.6	82 ± 6	-5.8
1.2.07.01.	Protein jagged-1	2vj2	Homo sapiens	Eukaryo. plasma	1	0	3.4 ± 1.8	84 ± 8	-5.8
1.1.39.02.	Biotin transporter BioY	4dve	Lactococcus lactis	Bact. Gram-pos plas.	1	6	31.8 ± 1.2	13 ± 1	-71.7
1.1.01.02.	Beta-1 adrenergic receptor, inactive, multiple mutations	2vt4	Meleagris gallopavo	Eukaryo. plasma	1	7	32.8 ± 1.6	3 ± 1	-74.6
1.2.41.01.	Acyl-CoA-binding domain-containing protein 5	3flv	Homo sapiens	Peroxisome	1	0	4.6 ± 2.8	28 ± 3	-4.9
1.1.69.01.	HIG1 domain family member 1B	2lon	Homo sapiens	Eukaryo. plasma	1	2	22.4 ± 1.2	19 ± 0	-13.7
1.3.20.01.	Colicin I receptor complex with binding domain of Colicin Ia	2hdi	Escherichia coli	Bact. Gram-neg outer	1	22	23.4 ± 0.9	3 ± 3	-72.7
1.1.01.02.	Neurotensin receptor type 1	4grv	Rattus norvegicus	Eukaryo. plasma	1	7	31.6 ± 1.1	4 ± 1	-75.1
1.3.14.01.	Toluene transporter TbuX	3bry	Ralstonia pickettii	Bact. Gram-neg outer	1	14	25.4 ± 1.5	1 ± 2	-57.7
1.1.09.01.	Copper efflux ATPase	3rfu	Legionella pneumophila	Bact. Gram-neg inner	1	8	30.0 ± 0.4	16 ± 1	-72.1
1.3.09.01.	Lipid A deacylase LpxR	3fid	Salmonella enterica	Bact. Gram-neg outer	1	12	25.6 ± 2.0	24 ± 0	-58.6
1.1.63.01.	Type 1 signal peptidase, apo-enzyme	1kn9	Escherichia coli	Bact. Gram-neg inner	1	0	3.4 ± 1.4	80 ± 6	-7.8
1.3.20.01.	Enantio-pyochelin receptor FetA	3qlb	Pseudomonas fluorescens	Bact. Gram-neg outer	1	22	23.4 ± 0.8	7 ± 0	-75.3
1.2.32.01.	Cytochrome P450 11B2, mitochondrial	4dvq	Homo sapiens	Mitochon. inner	1	0	4.8 ± 0.6	48 ± 4	-9.1
1.3.20.01.	Transferrin-binding protein A, complex with human serotransferrin	3v89	Neisseria meningitidis	Bact. Gram-neg outer	1	22	22.8 ± 0.8	3 ± 1	-68.9
1.2.38.01.	Penicillin-binding protein 1A	2oqo	Aquifex aeolicus	Bact. Gram-neg inner	1	0	3.0 ± 1.0	40 ± 6	-11.0
1.1.09.01.	Calcium ATPase, E2-Pi state, conformation 1	1wpg	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.6 ± 1.1	20 ± 0	-70.4
1.2.32.01.	Cytochrome P450 2B4, closed state 1	1suo	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	4.6 ± 1.3	57 ± 4	-14.2
1.1.51.01.	Vitamin K epoxide reductase	3kp9	Synechococcus sp.	Bact. Gram-neg inner	1	5	29.8 ± 1.6	0 ± 0	-45.1
1.2.34.01.	Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4 (OST4)	2lat	Homo sapiens	Endoplasm. reticulum	1	1	31.8 ± 3.5	23 ± 16	-21.3
1.3.19.01.	Outer membrane porin OprD, different conformation of loops	3sy7	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.8 ± 1.1	4 ± 2	-63.5
1.1.38.01.	Na+/drug antiporter NorM, outward-open	3mkt	Vibrio cholerae	Bact. Gram-neg inner	1	12	29.8 ± 1.1	9 ± 0	-74.0
1.1.15.01.	Nicotinic acetylcholine receptor, beta2 subunit, in hexafluoroisopropanol/water	2ksr	Homo sapiens	Eukaryo. plasma	1	4	29.1 ± 2.2	16 ± 1	-47.0
1.1.09.01.	Calcium ATPase, E2 state, Ca-free, conformation 7	3ar9	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.0 ± 0.9	20 ± 0	-73.8
1.1.01.02.	Rhodopsin, partially active, photobleached	2i37	Bos taurus	Eukaryo. plasma	1	7	31.9 ± 1.5	5 ± 1	-79.1
1.2.32.01.	Cytochrome P450 2A13	2p85	Homo sapiens	Endoplasm. reticulum	1	0	4.9 ± 0.4	47 ± 2	-10.0
1.2.32.01.	Cytochrome P450	1n97	Thermus thermophilus	Bact. Gram-neg inner	1	0	5.2 ± 0.3	43 ± 5	-9.9
1.1.09.01.	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3tlm	Bos taurus	Endoplasm. reticulum	1	10	26.8 ± 0.0	22 ± 0	-57.4
1.1.10.04.	P-glycoprotein, inward-facing conformation	3g5u	Mus musculus	Eukaryo. plasma	1	12	31.8 ± 1.2	4 ± 0	-100.6
1.1.26.05.	Glutamate/gamma-aminobutyrate antiporter	4dji	Escherichia coli	Bact. Gram-neg inner	1	12	30.0 ± 1.1	10 ± 1	-98.9
1.1.09.01.	Calcium ATPase, E2 state (Ca-free), conformation 2	2by4	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.8 ± 1.3	24 ± 1	-63.7
1.1.09.01.	Calcium ATPase, E2-Pi state, conformation 6	1xp5	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	27.4 ± 1.1	25 ± 0	-58.5
1.1.78.01.	Reticulon-4	2ko2	Mus musculus	Endoplasm. reticulum	1	0	2.5 ± 0.3	83 ± 1	-6.2
1.1.38.01.	Na+/drug antiporter NorM, outward-open	4hum	Neisseria gonorrhoeae	Bact. Gram-neg inner	1	12	28.6 ± 1.1	5 ± 1	-54.5
1.1.01.02.	Adenosine receptor A2a, partially active state, complex with agonist	3qak	Homo sapiens	Eukaryo. plasma	1	7	29.8 ± 1.2	9 ± 0	-70.0
1.2.32.01.	Plant cytochrome P450 74A (allene oxide synthase)	3dsk	Arabidopsis thaliana	Thylakoid	1	0	5.7 ± 0.5	67 ± 3	-20.0
1.1.01.02.	Histamine H1 receptor	3rze	Homo sapiens	Eukaryo. plasma	1	7	32.0 ± 1.4	1 ± 1	-72.4
1.2.04.01.	Integrin beta-3, cytoplasmic domain, monophosphorylated (747pY)	2ljf	Homo sapiens	Eukaryo. plasma	1	0	0.6 ± 1.6	62 ± 14	-1.8
1.1.60.01.	Protease GlpG, conformation 3	2irv	Escherichia coli	Bact. Gram-neg inner	1	6	28.2 ± 1.3	23 ± 5	-48.1
1.1.26.02.	Sodium-hydantoin transporter Mhp1, outward-facing conformation	2jln	Mycobacterium liquefaciens	Bact. Gram-pos plas.	1	12	29.8 ± 1.5	16 ± 0	-98.9
1.2.44.01.	Amyloid beta A4 protein (peptide 672-711)	1ba4	Homo sapiens	Eukaryo. plasma	1	0	6.0 ± 0.3	85 ± 5	-10.9
1.1.25.06.	D-xylose-proton symporter, conformation 3	4ja4	Escherichia coli	Bact. Gram-neg inner	1	12	28.2 ± 1.3	0 ± 0	-82.8
1.2.01.01.	Macrophage colony-stimulating factor 1 receptor	3bea	Homo sapiens	Eukaryo. plasma	1	0	2.9 ± 1.5	54 ± 19	-4.2
1.3.13.01.	Bacterial Nucleoside Transporter Ts	1tly	Escherichia coli	Bact. Gram-neg outer	1	12	23.4 ± 1.5	8 ± 0	-48.1
1.1.64.01.	Sodium/calcium exchanger	3v5u	Methanococcus jannaschii	Archaebac.	1	10	29.8 ± 0.9	3 ± 0	-78.4
1.2.18.01.	Putative sortase	2wts	Streptococcus pneumoniae	Bact. Gram-pos plas.	1	0	5.1 ± 1.0	20 ± 3	-4.6
1.2.37.01.	ADP-ribosyl cyclase 1	3f6y	Homo sapiens	Eukaryo. plasma	1	0	2.5 ± 2.4	51 ± 9	-6.3
1.2.24.01.	Protein Vpu, transmembrane helix	1pi7	Human immunodeficiency virus type 1	Eukaryo. plasma	1	1	28.2 ± 5.4	38 ± 4	-23.8
1.3.04.03.	Lipid A acylase PagP	3gp6	Escherichia coli	Bact. Gram-neg outer	1	8	24.7 ± 1.5	40 ± 1	-32.5
1.1.01.02.	Adenosine receptor A2a, complex with antagonist	3uza	Homo sapiens	Eukaryo. plasma	1	7	31.6 ± 0.6	8 ± 1	-72.5
1.3.20.01.	Ferric hydroxamate uptake receptor FhuA, complex with TonB	2grx	Escherichia coli	Bact. Gram-neg outer	1	22	24.6 ± 1.1	3 ± 0	-77.2
1.2.32.01.	Plant cytochrome P450 74A (allene oxide synthase)	3dan	Parthenium argentatum	Vacuole	1	0	7.5 ± 0.4	64 ± 2	-24.1
1.3.20.01.	Colicin I receptor	2hdf	Escherichia coli	Bact. Gram-neg outer	1	22	23.4 ± 0.9	4 ± 0	-70.9
1.1.01.02.	C-X-C chemokine receptor type 1	2lnl	Homo sapiens	Eukaryo. plasma	1	7	30.2 ± 0.9	19 ± 6	-54.4
1.3.14.01.	Toluene transporter TodX	3bs0	Pseudomonas putida	Bact. Gram-neg outer	1	14	23.4 ± 1.4	7 ± 7	-61.3
1.1.26.06.	Uracil transporter UraA	3qe7	Escherichia coli	Bact. Gram-neg inner	1	14	27.7 ± 1.2	16 ± 0	-79.3
1.1.01.02.	5-hydroxytryptamine receptor 2B	4ib4	Homo sapiens	Eukaryo. plasma	1	7	34.0 ± 2.3	16 ± 2	-69.2
1.3.20.01.	Outer membrane receptor FauA	3efm	Bordetella pertussis	Bact. Gram-neg outer	1	22	24.7 ± 0.6	11 ± 0	-77.5
1.3.11.01.	Hemoglobin-binding protease Hbp autotransporter	3aeh	Escherichia coli	Bact. Gram-neg outer	1	12	25.2 ± 1.1	4 ± 0	-41.9
1.2.09.01.	Stannin	1zza	Homo sapiens	Mitochon. outer	1	1	30.0 ± 2.0	13 ± 2	-25.2
1.1.34.01.	Mitochondrial uncoupling protein 2	2lck	Mus musculus	Mitochon. inner	1	6	30.0 ± 1.2	12 ± 1	-30.3
1.3.11.01.	Autotransporter BrkA	3qq2	Bordetella pertussis	Bact. Gram-neg outer	1	12	24.6 ± 1.5	4 ± 1	-44.1
1.2.22.01.	Activator of apoptosis harakiri, cytosolic helix	2l58	Homo sapiens	Mitochon. outer	1	0	2.4 ± 4.0	88 ± 0	-8.5
1.2.33.02.	Protoporphyrinogen oxidase	3nks	Homo sapiens	Mitochon. inner	1	0	4.8 ± 1.0	59 ± 3	-9.6
1.3.19.01.	Outer membrane porin OpdL	2y0h	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.0 ± 1.0	3 ± 0	-55.7
1.3.20.01.	Transferrin-binding protein A, complex with full-length transferrin	3v8x	Neisseria meningitidis	Bact. Gram-neg outer	1	24	23.2 ± 0.6	3 ± 0	-66.6
1.2.27.01.	Fst toxin	2kv5	Enterococcus faecalis	Secreted	1	1	26.0 ± 2.9	35 ± 8	-18.9
1.2.38.01.	Penicillin-binding protein 1B	3vma	Escherichia coli	Bact. Gram-neg inner	1	1	29.8 ± 2.0	25 ± 3	-21.6
1.1.09.01.	Calcium ATPase, E1-ATP state	1t5s	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.7 ± 1.6	22 ± 1	-58.6
1.2.32.01.	Cytochrome P450 2C8	1pq2	Homo sapiens	Endoplasm. reticulum	1	0	3.8 ± 1.8	65 ± 9	-8.6
1.3.14.01.	Fatty Acid Transporter FadL, D348R, open channel	3pgr	Escherichia coli	Bact. Gram-neg outer	1	14	25.4 ± 1.4	3 ± 1	-50.8
1.2.39.01.	Endoplasmic reticulum aminopeptidase 1, different conformation	2yd0	Homo sapiens	Endoplasm. reticulum	1	0	4.1 ± 2.2	59 ± 8	-4.6
1.1.46.01.	MerF bacterial mercury uptake transporter	2lj2	Morganella morganii	Bact. Gram-neg inner	1	2	28.8 ± 2.4	19 ± 1	-37.9
1.2.32.01.	Cytochrome P450 2D6, conformation 1	2f9q	Homo sapiens	Endoplasm. reticulum	1	0	7.0 ± 1.8	29 ± 10	-12.0
1.2.32.01.	Cytochrome P450 1A2	2hi4	Homo sapiens	Endoplasm. reticulum	1	0	6.9 ± 1.0	66 ± 9	-16.2
1.2.32.01.	Cytochrome P450 19A1 (aromatase, estrogen synthetase)	3eqm	Homo sapiens	Endoplasm. reticulum	1	0	6.1 ± 1.2	58 ± 8	-12.4
1.1.25.02.	Lactose permease, conformation 2	2v8n	Escherichia coli	Bact. Gram-neg inner	1	12	31.8 ± 0.8	5 ± 0	-86.4
1.2.32.01.	Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 2	3mdm	Homo sapiens	Endoplasm. reticulum	1	0	3.8 ± 1.3	51 ± 8	-5.9
1.1.44.01.	DsbB-DsbA complex, conformation 3	2leg	Escherichia coli	Bact. Gram-neg inner	1	4	30.6 ± 1.7	34 ± 2	-36.3
1.2.32.01.	Cytochrome P450 2B4, open state 3	3r1b	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	5.7 ± 0.0	43 ± 5	-9.8
1.1.70.01.	CAAX prenyl protease 1 homolog	4aw6	Homo sapiens	Endoplasm. reticulum	1	7	30.8 ± 1.3	13 ± 1	-75.9
1.1.09.01.	Calcium ATPase, E2 state, Ca-free, conformation 3	2ear	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.0 ± 1.2	19 ± 1	-58.4
1.1.09.01.	Calcium ATPase, E2-Pi state, conformation 7	3n5k	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	28.4 ± 1.3	22 ± 2	-64.8
1.1.75.01.	Sec-independent protein translocase TatC	4b4a	Aquifex aeolicus	Bact. Gram-neg inner	1	6	30.4 ± 1.2	17 ± 0	-51.7
1.1.03.02.	Light-harvesting complex CP29	3pl9	Spinacia oleracea	Thylakoid	1	3	29.8 ± 1.6	2 ± 2	-66.6
1.1.01.02.	Dopamine D3 receptor	3pbl	Homo sapiens	Eukaryo. plasma	1	7	33.0 ± 1.8	8 ± 1	-56.6
1.2.03.02.	T-cell immunoglobulin and mucin domain-containing protein 4	3bib	Mus musculus	Eukaryo. plasma	1	0	3.2 ± 1.9	41 ± 7	-4.6
1.2.03.03.	Myelin protein P0	3oai	Homo sapiens	Eukaryo. plasma	1	0	2.2 ± 1.2	72 ± 6	-5.8
1.2.01.01.	Focal adhesion kinase 1	2j0k	Gallus gallus	Eukaryo. plasma	1	0	5.0 ± 2.1	36 ± 2	-4.1
1.3.14.01.	Fatty Acid Transporter FadL	1t16	Escherichia coli	Bact. Gram-neg outer	1	14	25.4 ± 1.3	6 ± 7	-58.0
1.1.56.01.	Glycerol phosphate lipoteichoic acid synthase 2	2w8d	Bacillus subtilis	Bact. Gram-pos plas.	1	0	0.0 ± 6.0	83 ± 58	-1.6
1.2.03.07.	Netrin receptor UNC5B	3g5b	Rattus norvegicus	Eukaryo. plasma	1	0	1.9 ± 2.5	90 ± 14	-8.5
1.1.01.02.	Muscarinic acetylcholine receptor M2	3uon	Homo sapiens	Eukaryo. plasma	1	7	31.8 ± 2.1	4 ± 2	-68.5
1.3.19.02.	Alginate export protein, AlgE	3rbh	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.4 ± 1.2	4 ± 0	-72.0
1.1.15.01.	Nicotinic acetylcholine receptor, alpha4 subunit, in LDAO micelles	2lly	Homo sapiens	Eukaryo. plasma	1	4	29.2 ± 1.2	8 ± 1	-49.2
1.3.20.01.	Outer membrane cobalamin transporter BtuB, complex with TonB	2gsk	Escherichia coli	Bact. Gram-neg outer	1	22	23.4 ± 0.7	5 ± 0	-77.5
1.2.44.01.	Amyloid beta A4 protein (peptide 671-770)	2lp1	Homo sapiens	Eukaryo. plasma	1	1	23.6 ± 5.6	38 ± 5	-21.2
1.3.19.01.	Protein OpdK	2qtk	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.3 ± 1.0	3 ± 0	-62.4
1.1.01.02.	5-hydroxytryptamine receptor 1B, conformation 1	4iar	Homo sapiens	Eukaryo. plasma	1	7	33.6 ± 1.8	7 ± 1	-76.4
1.3.20.01.	Outer membrane heme transporter ShuA	3fhh	Shigella dysenteriae	Bact. Gram-neg outer	1	22	24.6 ± 0.9	5 ± 0	-70.7
1.1.25.03.	Multidrug transporter EmrD	2gfp	Escherichia coli	Bact. Gram-neg inner	1	12	31.6 ± 1.5	9 ± 0	-58.0
1.2.22.01.	Activator of apoptosis harakiri, transmembrane helix	2l5b	Homo sapiens	Mitochon. outer	1	1	29.8 ± 0.9	14 ± 11	-11.9
1.2.32.01.	Cytochrome P450 24a1 (1,25-dihydroxyvitamin D(3) 24-hydroxylase)	3k9v	Rattus norvegicus	Mitochon. inner	1	0	6.6 ± 1.0	49 ± 6	-9.6
1.3.21.01.	Outer membrane usher protein FimD	3ohn	Escherichia coli	Bact. Gram-neg outer	1	24	21.2 ± 1.1	5 ± 0	-45.4
1.1.67.01.	Transmembrane proteins 14A	2lop	Homo sapiens	Mitochon. inner	1	3	28.8 ± 2.0	23 ± 1	-35.5
1.3.19.01.	Pyroglutamate porin OpdO	2y0k	Pseudomonas aeruginosa	Bact. Gram-neg outer	1	18	23.8 ± 1.2	1 ± 0	-55.8
1.3.11.02.	Intimin	4e1s	Escherichia coli	Bact. Gram-neg outer	1	12	24.4 ± 1.6	9 ± 2	-45.2
1.1.09.01.	Calcium ATPase, E1P-ADP state	2zbd	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	31.8 ± 1.4	22 ± 2	-70.6
1.3.25.01.	Necrotic enteritis toxin B	4i0n	Clostridium perfringens	Secreted	1	0	1.6 ± 2.4	38 ± 7	-4.3
1.2.32.01.	Cytochrome P450 2C9	1og5	Homo sapiens	Endoplasm. reticulum	1	0	7.6 ± 1.0	79 ± 6	-13.7
1.3.14.01.	Fatty Acid Transporter FadL, F3E, open channel	3pgu	Escherichia coli	Bact. Gram-neg outer	1	14	25.2 ± 1.5	1 ± 1	-51.5
1.1.47.01.	Sensor protein kdpD	2ksf	Escherichia coli	Bact. Gram-neg inner	1	4	26.2 ± 4.0	45 ± 1	-27.9
1.2.39.01.	Endoplasmic reticulum aminopeptidase 1	3mdj	Homo sapiens	Endoplasm. reticulum	1	0	1.9 ± 3.6	63 ± 10	-4.6
1.2.32.01.	Cytochrome P450 2B4, open state 1	2bdm	Oryctolagus cuniculus	Endoplasm. reticulum	1	0	10.6 ± 1.0	48 ± 15	-16.2
1.1.01.02.	Rhodopsin, inactive, complex with inverse agonist, 11-cis retinal	1gzm	Bos taurus	Eukaryo. plasma	1	7	32.2 ± 1.5	11 ± 1	-75.6
1.2.32.01.	Prostacyclin synthase (cytochrome P450 8A1)	3b6h	Homo sapiens	Endoplasm. reticulum	1	0	5.0 ± 1.6	64 ± 18	-6.3
1.2.12.01.	Fimbrial protein, monomer	1oqw	Pseudomonas aeruginosa	Bact. Gram-neg inner	1	1	29.8 ± 3.0	31 ± 8	-28.9
1.2.32.01.	Sterol 14-alpha-demethylase (CYP51)	3ld6	Homo sapiens	Endoplasm. reticulum	1	0	8.9 ± 0.6	57 ± 2	-16.8
1.1.01.02.	Beta-2 adrenergic receptor, active state, complex with G-protein	3sn6	Homo sapiens	Eukaryo. plasma	1	7	31.0 ± 1.6	8 ± 1	-68.2
1.1.52.01.	Oligosaccharyltransferase PglB	3rce	Campylobacter lari	Bact. Gram-neg inner	1	13	28.8 ± 0.9	8 ± 0	-89.6
1.2.32.01.	Cytochrome P450 3A4, conformation 2	3nxu	Homo sapiens	Endoplasm. reticulum	1	0	9.3 ± 1.0	52 ± 12	-17.5
1.1.01.03.	Ectodomain of G-protein coupled receptor Mth	1fjr	Drosophila melanogaster	Eukaryo. plasma	1	0	1.8 ± 1.5	56 ± 13	-4.3
1.1.01.01.	Green-light absorbing proteorhodopsin	2l6x	Gamma-proteobacterium	Bact. Gram-neg inner	1	7	27.8 ± 1.3	18 ± 1	-55.2
1.2.39.01.	Endoplasmic reticulum aminopeptidase 2	3se6	Homo sapiens	Endoplasm. reticulum	1	0	2.5 ± 1.8	60 ± 21	-4.5
1.2.32.01.	Cytochrome P450 2D6, conformation 2	3tda	Homo sapiens	Endoplasm. reticulum	1	0	8.0 ± 0.7	35 ± 7	-12.5
1.1.09.01.	Calcium ATPase, E2 state (Ca-free), conformation 4	3fps	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.0 ± 0.9	16 ± 0	-53.5
1.1.09.01.	Calcium ATPase, E1-2Ca state, conformation 2	3ba6	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.8 ± 0.7	19 ± 0	-59.4
1.1.60.01.	Protease GlpG, complex with inhibitor, conformation 2	3zeb	Escherichia coli	Bact. Gram-neg inner	1	6	28.4 ± 1.3	12 ± 0	-64.0
1.2.32.01.	Cytochrome P450 120a1, different conformation	2ve3	Synechocystis sp.	Thylakoid	1	0	5.2 ± 1.5	52 ± 15	-6.8
1.1.01.01.	Archaerhodopsin-1	1uaz	Halobacterium sp.	Archaebac.	1	7	31.8 ± 1.3	9 ± 2	-65.3
1.2.03.02.	Hepatitis A virus cellular receptor 2 homolog	3kaa	Mus musculus	Eukaryo. plasma	1	0	2.8 ± 2.0	55 ± 16	-5.5
1.1.08.01.	F1F0 ATP synthase subunit c	1wu0	Bacillus ps3	Bact. Gram-pos plas.	1	2	31.9 ± 2.7	44 ± 1	-23.2
1.2.04.01.	Integrin alpha-IIb, cytoplasmic domain	1s4w	Homo sapiens	Eukaryo. plasma	1	0	2.9 ± 0.3	69 ± 3	-9.1
1.1.75.02.	Sec-independent protein translocase TatA	2lzr	Escherichia coli	Bact. Gram-neg inner	1	1	29.2 ± 1.8	26 ± 2	-29.1
1.2.33.02.	Alpha-glycerophosphate oxidase (GlpO)	2rgh	Streptomyces sp.	Bact. Gram-pos plas.	1	0	3.9 ± 1.4	71 ± 12	-6.2
1.1.59.01.	Membrane protease specific for a stomatin homolog, monomer	3bpp	Pyrococcus horikoshii	Archaebac.	1	0	4.0 ± 0.4	82 ± 5	-6.3
1.2.03.03.	Myelin protein P0	1neu	Rattus norvegicus	Eukaryo. plasma	1	0	5.4 ± 1.8	70 ± 8	-6.6
1.3.01.01.	Outer membrane protein A (OMPA), disordered loops	1qjp	Escherichia coli	Bact. Gram-neg outer	1	8	25.4 ± 1.5	11 ± 1	-29.5
1.2.03.05.	Prolactin receptor	3nce	Homo sapiens	Eukaryo. plasma	2	0	3.4 ± 1.5	68 ± 2	-5.7
1.1.27.01.	Ferrous-iron efflux pump fieF, different conformation	2qfi	Escherichia coli	Bact. Gram-neg inner	2	12	25.0 ± 1.3	1 ± 2	-32.4
1.2.19.01.	Mitochondrial import receptor subunit TOM20, 59-126, with presequence peptide	3awr	Rattus norvegicus	Mitochon. outer	2	0	5.0 ± 2.6	32 ± 7	-4.1
1.1.07.01.	Nitric oxide reductase	3o0r	Pseudomonas aeruginosa	Bact. Gram-neg inner	2	13	31.7 ± 1.6	5 ± 0	-107.7
1.2.01.01.	Receptor tyrosine kinase erbB-2, complex with EGF receptor	2ks1	Homo sapiens	Eukaryo. plasma	2	2	32.0 ± 2.5	15 ± 5	-50.6
1.1.11.01.	Ribosome-SecYE complex	3j01	Escherichia coli	Bact. Gram-neg inner	2	13	28.6 ± 0.0	5 ± 0	-86.4
1.1.27.01.	Zinc transporter YiiP, inward-facing conformation	3j1z	Shewanella oneidensis	Bact. Gram-neg inner	2	12	28.6 ± 1.2	8 ± 1	-54.4
1.1.10.02.	Molybdate transporter ModBC, open state	3d31	Methanosarcina acetivorans	Archaebac.	2	12	29.8 ± 1.5	1 ± 0	-91.6
1.1.09.01.	Plasma membrane ATPase	1mhs	Neurospora crassa	Eukaryo. plasma	2	20	29.5 ± 0.2	7 ± 0	-109.6
1.1.35.01.	Sodium/proton antiporter 1 (NhaA), dimer	3fi1	Escherichia coli	Bact. Gram-neg inner	2	24	28.4 ± 1.6	2 ± 1	-126.7
1.1.01.01.	Archaeal-type opsin 2	3ug9	Chlamydomonas reinhardtii	Eukaryo. plasma	2	14	31.0 ± 1.2	0 ± 0	-100.3
1.2.04.01.	Integrin beta-3/alpha-V complex	3ije	Homo sapiens	Eukaryo. plasma	2	0	6.1 ± 2.1	13 ± 14	-9.0
1.1.36.01.	ClC chloride transporter	1ots	Escherichia coli	Bact. Gram-neg inner	2	28	29.7 ± 0.8	0 ± 0	-115.3
1.1.12.01.	Potassium channel subfamily K member 4	3um7	Homo sapiens	Eukaryo. plasma	2	12	30.8 ± 1.2	3 ± 0	-93.2
1.1.26.01.	Leucine transporter LeuT, outward-facing substrate-bound conformation	2a65	Aquifex aeolicus	Bact. Gram-neg inner	2	28	29.8 ± 0.5	0 ± 0	-157.9
1.2.33.02.	Monoamine oxidase B, monomer	1s3e	Homo sapiens	Mitochon. outer	2	0	7.3 ± 0.6	37 ± 1	-14.2
1.1.10.02.	Maltose transporter MalFGK, outward conformation	3puw	Escherichia coli	Bact. Gram-neg inner	2	14	29.8 ± 1.3	3 ± 1	-94.0
1.1.05.04.	Succinate dehydrogenase (mitochondrial respiratory complex II)	1zoy	Sus scrofa	Mitochon. inner	2	6	29.8 ± 1.1	3 ± 6	-52.6
1.1.10.03.	Lipid flippase MsbA, open state	3b60	Salmonella enterica	Bact. Gram-neg inner	2	12	31.8 ± 0.9	0 ± 0	-98.5
1.1.11.01.	Protein translocase SecY, pre-open state	2zjs	Thermus thermophilus	Bact. Gram-neg inner	2	11	30.7 ± 1.2	7 ± 0	-100.7
1.1.10.05.	Mitochondrial ABC transporter ABCB10, conformation 3	4ayx	Homo sapiens	Mitochon. inner	2	12	30.0 ± 0.6	0 ± 0	-76.8
1.1.10.05.	Mitochondrial ABC transporter ABCB10, conformation 4	3zdq	Homo sapiens	Mitochon. inner	2	12	30.8 ± 0.5	1 ± 0	-71.8
1.2.17.03.	Syntaxin-1	2xhe	Monosiga brevicollis (Choanoflagellate)	Undefined	2	0	4.1 ± 2.3	78 ± 3	-5.3
2.3.04.01.	Corticosteroid 11-beta-dehydrogenase, isozyme 1	1y5m	Mus musculus	Endoplasm. reticulum	2	0	4.6 ± 0.4	89 ± 2	-19.3
1.1.01.02.	Opsin, active, retinal-free state, dimer	3cap	Bos taurus	Eukaryo. plasma	2	14	30.8 ± 1.1	0 ± 0	-130.1
1.2.01.01.	Receptor tyrosine kinase erbB-2, dimer	2jwa	Homo sapiens	Eukaryo. plasma	2	2	31.9 ± 2.9	13 ± 9	-46.6
1.1.77.01.	Cellulose-conducting channel	4hg6	Rhodobacter sphaeroides	Bact. Gram-neg inner	2	9	30.0 ± 1.3	17 ± 0	-85.0
1.2.01.01.	Receptor tyrosine-protein kinase erbB-3, peptide 640-670	2l9u	Homo sapiens	Eukaryo. plasma	2	2	33.8 ± 2.4	16 ± 5	-44.6
1.1.10.03.	Lipid flippase MsbA, closed state	3b5x	Vibrio cholerae	Bact. Gram-neg inner	2	12	30.2 ± 1.0	0 ± 0	-58.7
1.1.11.01.	Protein translocase SecY, partialy open	3mp7	Pyrococcus furiosus	Archaebac.	2	10	30.1 ± 1.0	5 ± 6	-94.0
1.2.36.01.	Hemagglutinin-neuraminidase glycoprotein	1v3e	Human parainfluenza virus 3	Eukaryo. plasma	2	0	1.9 ± 0.4	81 ± 34	-6.5
1.1.36.01.	ClC chloride transporter	1kpl	Salmonella enterica	Bact. Gram-neg inner	2	28	29.3 ± 0.8	2 ± 1	-128.0
1.2.14.01.	Transforming growth factor beta receptor type 3	3qw9	Rattus norvegicus	Eukaryo. plasma	2	0	3.1 ± 0.3	87 ± 4	-9.9
1.1.10.01.	ABC transporter BtuCD, symmetric structure	1l7v	Escherichia coli	Bact. Gram-neg inner	2	22	30.7 ± 1.1	0 ± 1	-121.0
1.1.12.01.	Potassium channel subfamily K member 1	3ukm	Homo sapiens	Eukaryo. plasma	2	12	31.8 ± 1.0	0 ± 0	-108.7
1.1.05.01.	Polysulfide reductase, inactive state	2vpz	Thermus thermophilus	Bact. Gram-neg inner	2	16	29.8 ± 1.5	1 ± 0	-105.2
1.1.12.01.	Potassium channel subfamily K member 4, different conformation	4i9w	Homo sapiens	Eukaryo. plasma	2	8	30.8 ± 1.4	6 ± 0	-106.2
1.2.33.02.	Monoamine oxidase A	1o5w	Rattus norvegicus	Mitochon. outer	2	2	31.4 ± 3.4	20 ± 3	-23.1
1.1.05.04.	Succinate dehydrogenase (mitochondrial respiratory complex II)	3vr8	Ascaris suum	Mitochon. inner	2	6	30.4 ± 1.2	10 ± 1	-57.1
1.3.25.01.	Gamma-hemolysin, heterodimer of components A and B	2qk7	Staphylococcus aureus	Secreted	2	0	2.9 ± 2.0	83 ± 11	-5.7
1.1.26.05.	Arginine/agmatine antiporter (AdiC), outward-facing conformation	3hqk	Salmonella enterica	Bact. Gram-neg inner	2	26	29.8 ± 1.0	0 ± 0	-124.6
1.1.10.02.	Maltose transporter MalFGK, inward conformation, TMH 1 deleted	3fh6	Escherichia coli	Bact. Gram-neg inner	2	13	29.9 ± 0.6	3 ± 1	-97.8
2.3.04.01.	Corticosteroid 11-beta-dehydrogenase, isozyme 1	1xu7	Homo sapiens	Endoplasm. reticulum	2	0	7.9 ± 0.2	89 ± 1	-20.2
1.1.26.05.	Arginine/agmatine transporter (AdiC), intermediate conformation	3ob6	Escherichia coli	Bact. Gram-neg inner	2	24	29.8 ± 1.4	3 ± 1	-158.7
1.2.01.01.	Receptor tyrosine-protein kinase erbB-4, peptide 642-685	2l2t	Homo sapiens	Eukaryo. plasma	2	2	32.4 ± 1.5	4 ± 2	-50.4
1.1.10.02.	Methionine importer MetNI, conformation 2	3tuj	Escherichia coli	Bact. Gram-neg inner	2	10	30.4 ± 1.3	7 ± 1	-84.5
1.2.01.01.	Receptor tyrosine kinase EphA1	2k1k	Homo sapiens	Eukaryo. plasma	2	2	30.2 ± 1.5	0 ± 5	-43.3
1.1.36.01.	ClC chloride transporter	3org	Cyanidoschyzon merolae	Eukaryo. plasma	2	28	28.7 ± 1.3	0 ± 2	-140.4
1.2.05.01.	Toll-like receptor 4 complex	2z64	Mus musculus	Eukaryo. plasma	2	0	1.1 ± 3.1	51 ± 19	-6.3
1.2.44.01.	Amyloid beta A4 protein, peptide 686-726, dimer	2loh	Homo sapiens	Eukaryo. plasma	2	2	32.8 ± 1.6	1 ± 1	-34.1
1.1.05.04.	Succinate dehydrogenase (mitochondrial respiratory complex II)	1yq3	Gallus gallus	Mitochon. inner	2	6	29.6 ± 1.8	4 ± 6	-56.7
1.1.10.05.	Mitochondrial ABC transporter ABCB10, conformation 1	4ayt	Homo sapiens	Mitochon. inner	2	12	30.4 ± 0.8	0 ± 0	-79.7
1.1.12.03.	Potassium uptake protein TrkH	3pjz	Vibrio parahaemolyticus	Bact. Gram-neg inner	2	20	29.7 ± 0.6	1 ± 0	-164.0
1.2.04.01.	Integrin alpha-IIb, complex with integrin beta-3	2knc	Homo sapiens	Eukaryo. plasma	2	2	34.8 ± 1.4	13 ± 5	-46.2
1.1.01.02.	Opioid mu receptor	4dkl	Mus musculus	Eukaryo. plasma	2	14	32.0 ± 1.0	5 ± 0	-134.7
1.1.09.01.	Calcium ATPase, E1 Mg2+ state, complex with sarcolipin	3w5a	Oryctolagus cuniculus	Endoplasm. reticulum	2	11	26.8 ± 0.7	30 ± 0	-67.4
1.1.72.01.	Dicarboxylate/sodium symporter NadC	4f35	Vibrio cholerae	Bact. Gram-neg inner	2	28	27.8 ± 0.2	1 ± 0	-82.5
1.1.05.01.	Polysulfide reductase, substrate-bound state	2vpx	Thermus thermophilus	Bact. Gram-neg inner	2	16	27.1 ± 1.1	0 ± 1	-103.3
1.1.26.01.	Leucine transporter LeuT, outward-facing substrate-free conformation	3tt1	Aquifex aeolicus	Bact. Gram-neg inner	2	24	28.2 ± 1.2	0 ± 0	-160.8
1.1.09.01.	Copper efflux ATPase, CopA, alternative conformation	3j09	Archaeoglobus fulgidus	Archaebac.	2	16	27.0 ± 0.1	1 ± 0	-23.5
1.2.03.02.	Sialoadhesin	1url	Mus musculus	Eukaryo. plasma	2	0	3.7 ± 1.8	83 ± 12	-4.0
1.1.05.04.	Fumarate reductase	2bs2	Wolinella succinogenes	Bact. Gram-neg inner	2	10	31.4 ± 1.3	2 ± 0	-118.8
1.2.01.01.	Epidermal growth factor receptor, erbB-1, homodimer (642-697)	2m20	Homo sapiens	Eukaryo. plasma	2	2	34.0 ± 3.0	0 ± 3	-52.5
1.1.01.04.	Smoothened homolog	4jkv	Homo sapiens	Eukaryo. plasma	2	14	31.9 ± 1.2	0 ± 0	-98.5
1.2.33.02.	Monoamine oxidase B, dimer	2xfn	Homo sapiens	Mitochon. outer	2	2	30.0 ± 3.2	14 ± 0	-14.5
1.2.21.01.	BNip3 transmembrane domain homodimer, second alternative structure	2j5d	Homo sapiens	Mitochon. outer	2	2	30.8 ± 2.5	12 ± 0	-35.8
1.1.12.03.	TrkH/TrkA potassium transport complex	4j9u	Vibrio parahaemolyticus	Bact. Gram-neg inner	2	20	29.4 ± 0.7	0 ± 0	-151.9
1.1.01.02.	Squid rhodopsin, inactive, complex with inverse agonist 11-cis retinal, dimer	2z73	Todarodes pacificus	Eukaryo. plasma	2	14	32.9 ± 1.0	0 ± 1	-143.3
2.3.04.01.	Corticosteroid 11-beta-dehydrogenase, isozyme 1	3g49	Cavia porcellus	Endoplasm. reticulum	2	0	7.0 ± 0.5	90 ± 1	-15.9
1.1.10.02.	Maltose transporter MalFGK, a pre-translocation state	3puz	Escherichia coli	Bact. Gram-neg inner	2	14	29.0 ± 0.8	7 ± 0	-107.2
1.2.02.01.	Zeta-zeta dimer of T cell receptor	2hac	Homo sapiens	Eukaryo. plasma	2	2	31.9 ± 2.3	7 ± 10	-43.2
1.1.09.01.	Calcium ATPase, E1 Ca2+ state, complex with sarcolipin	4h1w	Oryctolagus cuniculus	Endoplasm. reticulum	2	11	27.6 ± 1.0	27 ± 1	-67.6
1.2.17.01.	SNARE complex (syntaxin 1A, SNAP-25 and synaptobrevin 2)	3hd7	Rattus norvegicus	Eukaryo. plasma	2	2	28.5 ± 1.9	3 ± 7	-29.3
1.1.26.01.	Leucine transporter LeuT, outward-facing conformation, from bicelles	4fxz	Aquifex aeolicus	Bact. Gram-neg inner	2	24	28.0 ± 0.6	0 ± 0	-144.3
1.1.01.02.	C-X-C chemokine receptor type 4, inactive, with cyclic peptide antagonist	3oe0	Homo sapiens	Eukaryo. plasma	2	14	32.2 ± 2.0	5 ± 6	-133.2
1.1.01.02.	Rhodopsin, active (metarhodopsin II), without transducin peptide, dimer	3pxo	Bos taurus	Eukaryo. plasma	2	14	31.8 ± 1.2	0 ± 0	-125.4
1.1.11.01.	Protein translocase SecY, closed state	2zqp	Thermus thermophilus	Bact. Gram-neg inner	2	11	29.8 ± 0.4	9 ± 0	-99.4
1.1.10.03.	Multidrug ABC transporter SAV1866, closed state	2hyd	Staphylococcus aureus	Bact. Gram-pos plas.	2	12	31.8 ± 1.7	3 ± 3	-110.5
1.3.12.01.	Outer membrane phospholipase A	1qd6	Escherichia coli	Bact. Gram-neg outer	2	12	23.9 ± 1.0	0 ± 0	-77.2
1.1.43.01.	Saccharide transporter component, EIIC (ChbC)	3qnq	Bacillus cereus	Bact. Gram-pos plas.	2	20	29.6 ± 1.0	1 ± 0	-140.6
1.1.12.03.	TrkH/TrkA potassium transport complex	4j7c	Bacillus subtilis	Bact. Gram-pos plas.	2	16	31.8 ± 1.0	0 ± 0	-165.6
1.1.01.02.	Opioid kappa receptor	4djh	Homo sapiens	Eukaryo. plasma	2	14	32.0 ± 0.8	1 ± 0	-146.6
1.1.05.03.	Respiratory Nitrate Reductase	1q16	Escherichia coli	Bact. Gram-neg inner	2	10	30.1 ± 0.9	0 ± 0	-126.9
1.1.01.02.	Beta-1 adrenergic receptor, inactive, dimer	4gpo	Meleagris gallopavo	Eukaryo. plasma	2	14	30.8 ± 1.2	0 ± 0	-144.8
1.2.21.01.	BNip3 transmembrane domain homodimer	2ka2	Homo sapiens	Mitochon. outer	2	2	30.8 ± 1.8	4 ± 2	-29.2
1.2.31.01.	Cytochrome c nitrite reductase complex	2j7a	Desulfovibrio vulgaris	Bact. Gram-neg inner	2	2	31.8 ± 3.1	0 ± 2	-42.9
1.2.21.01.	BNip3 transmembrane domain homodimer, first alternative structure	2ka1	Homo sapiens	Mitochon. outer	2	2	31.8 ± 2.3	24 ± 8	-34.9
1.1.10.05.	Mitochondrial ABC transporter ABCB10, conformation 2	4ayw	Homo sapiens	Mitochon. inner	2	12	29.0 ± 0.8	0 ± 0	-65.8
1.1.26.03.	Sodium/sugar symporter vSGLT, substrate-bound	3dh4	Vibrio parahaemolyticus	Bact. Gram-neg inner	2	30	30.0 ± 0.7	0 ± 0	-184.0
1.1.27.01.	Ferrous-iron efflux pump fieF	3h90	Escherichia coli	Bact. Gram-neg inner	2	12	29.6 ± 0.8	0 ± 2	-83.9
1.2.15.02.	Signal recognition particle receptor	1nrj	Saccharomyces cerevisiae	Endoplasm. reticulum	2	0	3.9 ± 1.4	82 ± 11	-5.5
1.1.01.02.	Beta-2 adrenergic receptor, inactive state, dimer	2rh1	Homo sapiens	Eukaryo. plasma	2	14	31.8 ± 0.9	0 ± 1	-143.2
1.1.66.01.	K(+)-stimulated pyrophosphate-energized sodium pump, state1	4av3	Thermotoga maritima	Bact. Gram-neg inner	2	32	29.8 ± 0.7	0 ± 0	-182.5
1.1.01.02.	C-X-C chemokine receptor type 4, inactive, dimer, complex with antagonist	3odu	Homo sapiens	Eukaryo. plasma	2	17	31.2 ± 1.1	0 ± 0	-129.5
1.1.10.01.	ABC transporter BtuCD, complex with BtuF, structure 2	4dbl	Escherichia coli	Bact. Gram-neg inner	2	20	29.4 ± 1.0	4 ± 0	-123.4
1.1.09.01.	Copper efflux ATPase, CopA	3j08	Archaeoglobus fulgidus	Archaebac.	2	16	27.6 ± 0.8	0 ± 0	-72.3
1.1.39.03.	Energy-coupling factor transporter EcfA, conformation 1	4hzu	Lactobacillus brevis	Bact. Gram-pos plas.	2	7	29.7 ± 1.6	13 ± 1	-64.8
1.1.05.05.	Fumarate reductase	1kf6	Escherichia coli	Bact. Gram-neg inner	2	6	30.2 ± 1.2	14 ± 2	-65.6
1.2.01.01.	Platelet-derived growth factor receptor beta, 526-563	2l6w	Homo sapiens	Eukaryo. plasma	2	2	34.8 ± 0.8	18 ± 1	-40.9
1.1.10.01.	ABC transporter permease HI1471	2nq2	Haemophilus influenzae	Bact. Gram-neg inner	2	20	31.9 ± 0.9	1 ± 1	-124.2
1.1.10.01.	ABC transporter BtuCD, complex with BtuF, structure 1	2qi9	Escherichia coli	Bact. Gram-neg inner	2	22	29.4 ± 0.9	4 ± 4	-123.5
1.2.10.01.	Glycophorin A	1afo	Homo sapiens	Eukaryo. plasma	2	2	31.9 ± 2.8	5 ± 6	-43.5
1.1.36.01.	ClC chloride transporter	3nd0	Synechocystis sp.	Bact. Gram-neg inner	2	28	29.8 ± 0.7	0 ± 1	-120.9
1.2.08.01.	TYRO protein tyrosine kinase-binding protein, homodimer	2l34	Homo sapiens	Eukaryo. plasma	2	2	31.8 ± 3.0	14 ± 10	-36.0
1.1.01.02.	Rhodopsin, inactive state, a dimer	2i36	Bos taurus	Eukaryo. plasma	2	14	30.0 ± 1.4	4 ± 4	-125.6
2.3.04.01.	Sorbitol dehydrogenase	1k2w	Rhodobacter sphaeroides	Bact. Gram-neg inner	2	0	2.2 ± 0.3	89 ± 1	-4.4
1.2.04.01.	Integrin alpha-IIb, complex with integrin beta-3	2k9j	Homo sapiens	Eukaryo. plasma	2	2	36.4 ± 3.3	20 ± 1	-56.4
1.1.10.03.	ABC transporter, inward-facing conformation	3qf4	Thermotoga maritima	Bact. Gram-neg inner	2	12	32.0 ± 0.8	2 ± 0	-104.9
1.2.01.01.	Receptor tyrosine kinase EphA2	2k9y	Homo sapiens	Eukaryo. plasma	2	2	31.8 ± 3.2	12 ± 14	-32.1
1.1.10.01.	ABC transporter BtuCD, nucleotide-bound state	4fi3	Escherichia coli	Bact. Gram-neg inner	2	20	29.0 ± 1.0	0 ± 0	-118.3
1.1.09.01.	Sodium-potassium pump, gastric	2xzb	Sus scrofa	Eukaryo. plasma	2	11	29.7 ± 1.2	9 ± 0	-91.4
1.1.10.02.	Methionine importer MetNI, conformation 3	3dhw	Escherichia coli	Bact. Gram-neg inner	2	10	29.2 ± 1.0	1 ± 0	-82.5
1.2.04.01.	Integrin beta-1, complex with talin-2	3g9w	Homo sapiens	Eukaryo. plasma	2	0	8.7 ± 2.5	83 ± 6	-6.6
1.1.66.01.	K(+)-stimulated pyrophosphate-energized sodium pump, state2	4av6	Thermotoga maritima	Bact. Gram-neg inner	2	32	29.8 ± 0.8	0 ± 0	-173.1
1.1.10.02.	Molybdate transporter ModBC, open state	2onk	Archaeoglobus fulgidus	Archaebac.	2	12	32.0 ± 1.7	0 ± 1	-100.7
1.1.59.01.	Membrane protease specific for a stomatin homolog, dimer	3viv	Pyrococcus horikoshii	Archaebac.	2	0	4.5 ± 0.4	88 ± 9	-9.5
1.2.03.07.	Cell adhesion molecule complex	3n1f	Homo sapiens	Eukaryo. plasma	2	0	5.2 ± 0.9	59 ± 4	-5.7
1.1.66.01.	Proton-translocating pyrophosphatase	4a01	Vigna radiata (Mung bean)	Vacuole	2	32	32.0 ± 0.8	0 ± 0	-189.3
1.1.26.05.	Arginine/agmatine transporter (AdiC), substrate-bound	3l1l	Escherichia coli	Bact. Gram-neg inner	2	24	28.8 ± 1.4	2 ± 2	-132.0
1.1.09.01.	Sodium-potassium pump, gastric, different conformation	2yn9	Sus scrofa	Eukaryo. plasma	2	11	30.6 ± 0.8	10 ± 0	-85.9
1.1.41.01.	Magnesium ion transporter-E (MgtE)	2yvx	Thermus thermophilus	Bact. Gram-neg inner	2	10	31.1 ± 0.9	0 ± 0	-69.2
1.2.19.01.	Mitochondrial import receptor subunit TOM20, 51-145, with presequence peptide	1om2	Rattus norvegicus	Mitochon. outer	2	0	2.9 ± 2.7	76 ± 7	-4.8
1.1.10.02.	Methionine importer MetNI, conformation 1	3tui	Escherichia coli	Bact. Gram-neg inner	2	10	30.2 ± 1.3	1 ± 1	-81.0
1.1.26.05.	Arginine/agmatine antiporter (AdiC), outward-facing conformation	3h5m	Escherichia coli	Bact. Gram-neg inner	2	26	29.0 ± 0.8	0 ± 0	-128.9
1.1.26.03.	Sodium/sugar symporter vSGLT, substrate-free	2xq2	Vibrio parahaemolyticus	Bact. Gram-neg inner	2	30	30.4 ± 0.6	0 ± 0	-162.7
1.1.01.02.	Rhodopsin, constitutively active mutant (metarhodopsin II), dimer	2x72	Bos taurus	Eukaryo. plasma	2	14	30.0 ± 0.6	0 ± 0	-132.0
1.1.63.01.	Signal peptidase I	3iiq	Escherichia coli	Bact. Gram-neg inner	2	0	4.3 ± 0.5	57 ± 2	-10.2
1.1.10.01.	Hemin transport system permease, HmuU	4g1u	Yersinia pestis	Bact. Gram-neg inner	2	20	29.8 ± 0.5	0 ± 0	-114.3
1.2.08.01.	TYRO protein tyrosine kinase-binding protein, heterotrimer	2l35	Homo sapiens	Eukaryo. plasma	2	3	31.6 ± 3.2	20 ± 5	-40.3
1.3.16.01.	Porin OmpF	3pox	Escherichia coli	Bact. Gram-neg outer	3	48	24.0 ± 0.8	0 ± 0	-136.2
1.1.02.01.	Photosynthetic reaction center, complex with cytochrome c	1dxr	Rhodopseudomonas viridis	Bact. Gram-neg inner	3	11	31.8 ± 0.7	5 ± 0	-121.8
1.3.16.01.	Osmoporin OMPC, isoform 2	2ixw	Escherichia coli	Bact. Gram-neg outer	3	48	24.5 ± 1.0	0 ± 0	-121.0
1.3.23.01.	Autotransporter Hia, 937-1098, a different conformation	3emo	Haemophilus influenzae	Bact. Gram-neg outer	3	12	22.8 ± 1.9	4 ± 0	-40.1
1.2.43.03.	Envelope glycoprotein B	3nw8	Human herpesvirus	Viral	3	0	4.6 ± 0.0	1 ± 1	-11.7
1.1.28.02.	Efflux transporter CusA, Cu(i) complex	3kss	Escherichia coli	Bact. Gram-neg inner	3	33	28.8 ± 0.5	0 ± 0	-147.7
1.1.28.01.	Multidrug efflux transporter AcrB, asymmetric	2gif	Escherichia coli	Bact. Gram-neg inner	3	36	29.0 ± 0.2	1 ± 0	-187.5
1.1.28.01.	Multidrug efflux transporter AcrB, asymmetric, complex with ankyrin repeat 2	3nog	Escherichia coli	Bact. Gram-neg inner	3	36	29.0 ± 0.5	3 ± 0	-202.9
1.1.01.01.	Bacteriorhodopsin, trimer, complex with annular lipids	2zzl	Halobacterium salinarum	Archaebac.	3	21	29.8 ± 0.6	0 ± 0	-119.0
1.1.32.01.	Proton glutamate symport protein, outward-facing state	2nwl	Pyrococcus horikoshii	Archaebac.	3	39	29.8 ± 1.3	0 ± 0	-202.1
1.3.16.01.	Porin	1osm	Klebsiella pneumoniae	Bact. Gram-neg outer	3	48	24.0 ± 1.1	0 ± 0	-136.6
1.1.57.02.	Intramembrane aspartate protease	4hyg	Methanoculleus marisnigri	Archaebac.	3	27	31.8 ± 0.3	0 ± 0	-172.7
1.1.26.04.	Glycine betaine transporter BetP, asymmetric trimer, conformation 1	4ain	Corynebacterium glutamicum	Bact. Gram-pos plas.	3	36	29.8 ± 0.6	0 ± 0	-198.8
1.1.13.02.	ATP-gated P2X4 ion channel, open state	4dw1	Danio rerio	Eukaryo. plasma	3	6	26.8 ± 0.6	0 ± 0	-56.0
1.2.43.04.	Glycoprotein G	2cmz	Vesicular stomatitis virus	Viral	3	0	6.6 ± 0.0	3 ± 0	-10.5
1.3.16.01.	Porin OmpF	3nsg	Salmonella enterica	Bact. Gram-neg outer	3	48	23.6 ± 0.8	0 ± 0	-123.4
1.1.54.01.	Diacylglycerol kinase (DAGK)	2kdc	Escherichia coli	Bact. Gram-neg inner	3	9	25.5 ± 1.8	0 ± 0	-39.9
1.1.17.02.	Urea transporter	3k3f	Desulfovibrio vulgaris	Bact. Gram-neg inner	3	30	29.4 ± 0.8	0 ± 0	-124.4
1.3.24.01.	Outer membrane protein TolC, mutant, open conformation 1	2wmz	Escherichia coli	Bact. Gram-neg outer	3	12	24.4 ± 0.8	0 ± 0	-52.8
1.1.09.01.	Sodium-potassium pump, E2-Pi state	2zxe	Squalus acanthias	Eukaryo. plasma	3	12	31.9 ± 1.8	9 ± 0	-96.3
1.1.07.01.	Bacterial cytochrome c oxidase, caa3-type	2yev	Thermus thermophilus	Bact. Gram-neg inner	3	21	31.2 ± 0.8	6 ± 0	-146.1
1.1.11.01.	Protein translocase SecY, closed state, mutant	1rh5	Methanococcus jannaschii	Archaebac.	3	12	29.0 ± 1.1	10 ± 0	-93.4
1.1.01.01.	Bacteriorhodopsin, from cubic phase	1ap9	Halobacterium salinarum	Archaebac.	3	21	30.6 ± 1.2	0 ± 0	-97.8
1.3.16.01.	Anion-selective porin	2fgq	Comamonas acidovorans	Bact. Gram-neg outer	3	48	25.0 ± 0.9	0 ± 0	-130.8
1.3.24.01.	Outer membrane protein TolC, mutant, open conformation 2	2vde	Escherichia coli	Archaebac.	3	12	24.4 ± 1.2	0 ± 0	-57.4
1.3.16.01.	Osmoporin OMPC	2j1n	Escherichia coli	Bact. Gram-neg outer	3	48	25.1 ± 1.2	0 ± 2	-126.2
1.1.28.01.	Multidrug efflux transporter AcrB, asymmetric, complex with ankyrin repeat 1	4dx5	Escherichia coli	Bact. Gram-neg inner	3	36	27.4 ± 0.7	1 ± 0	-181.0
1.3.16.01.	Porin B (PorB)	4aui	Neisseria gonorrhoeae	Bact. Gram-neg outer	3	48	24.2 ± 0.8	0 ± 0	-89.7
1.3.24.01.	Outer membrane protein TolC, mutant, open conformation 3	2vdd	Escherichia coli	Bact. Gram-neg outer	3	12	24.4 ± 1.2	0 ± 0	-57.7
1.1.26.04.	L-carnitine/gamma-butyrobetaine antiporter CaiT, substrate-bound	3hfx	Escherichia coli	Bact. Gram-neg inner	3	42	29.8 ± 0.8	0 ± 0	-203.5
1.1.26.04.	L-carnitine/gamma-butyrobetaine antiporter CaiT, open inward-facing conformation	2wsx	Escherichia coli	Bact. Gram-neg inner	3	42	28.6 ± 0.7	7 ± 0	-212.7
1.1.61.01.	Leukotriene C4 synthase	2uuh	Homo sapiens	Endoplasm. reticulum	3	12	29.4 ± 1.1	0 ± 0	-55.2
1.1.17.02.	Urea transporter 1	4ezc	Bos taurus	Eukaryo. plasma	3	30	31.2 ± 0.6	0 ± 0	-138.8
1.1.28.02.	Efflux transporter CusA, complex with CusB, pre-extrusion state	3t56	Escherichia coli	Bact. Gram-neg inner	3	36	30.4 ± 0.6	0 ± 0	-153.7
1.1.03.02.	Light-Harvesting Complex II	2bhw	Pisum sativum	Thylakoid	3	9	29.4 ± 1.0	0 ± 0	-123.2
1.1.01.01.	Archaerhodopsin-2, trimeric	2ei4	Halobacterium sp.	Archaebac.	3	21	30.5 ± 1.2	0 ± 1	-143.9
1.1.26.04.	Glycine betaine transporter BetP, substrate-bound	2wit	Corynebacterium glutamicum	Bact. Gram-pos plas.	3	36	30.4 ± 1.2	0 ± 0	-198.6
1.1.11.01.	Protein translocase SecY, complex with ribosome 1	3dkn	Methanococcus jannaschii	Archaebac.	3	12	27.8 ± 1.8	2 ± 0	-80.9
1.3.16.02.	Porin	2por	Rhodobacter capsulatus	Bact. Gram-neg outer	3	48	23.4 ± 0.6	0 ± 0	-114.8
1.1.01.01.	Bacteriorhodopsin, different loop conformaton	1fbk	Halobacterium salinarum	Archaebac.	3	21	30.0 ± 1.2	0 ± 0	-127.8
1.3.16.01.	Phosphoporin (PhoE)	1pho	Escherichia coli	Bact. Gram-neg outer	3	48	24.1 ± 1.2	0 ± 0	-134.1
1.1.07.01.	Ubiquinol Oxidase	1fft	Escherichia coli	Bact. Gram-neg inner	3	19	29.5 ± 0.6	12 ± 0	-82.3
1.2.43.01.	Major envelope glycoprotein E, ectodomain	1ok8	Dengue virus	Viral	3	0	5.2 ± 0.9	0 ± 6	-9.5
1.1.61.01.	Microsomal prostaglandin E synthase 1, different conformation	4al0	Homo sapiens	Eukaryo. plasma	3	12	28.8 ± 1.0	0 ± 1	-79.7
1.2.43.05.	Major envelope glycoprotein	3duz	Autographa californica nuclear polyhedrosis virus	Viral	3	0	3.2 ± 0.4	4 ± 6	-9.3
1.1.17.01.	Ammonia channel, complex with inhibitory GlnK	2ns1	Escherichia coli	Bact. Gram-neg inner	3	33	29.1 ± 0.7	0 ± 0	-148.7
1.3.24.01.	Outer membrane protein TolC, mutant, open conformation 4	2xmn	Escherichia coli	Bact. Gram-neg outer	3	12	23.6 ± 1.4	0 ± 0	-50.5
1.1.26.04.	L-carnitine/gamma-butyrobetaine antiporter CaiT, open inward-facing conformation	2wsw	Proteus mirabilis	Bact. Gram-neg inner	3	42	29.8 ± 0.5	0 ± 0	-218.9
1.1.07.01.	Bacterial cytochrome c oxidase	3s8g	Thermus thermophilus	Bact. Gram-neg inner	3	15	31.2 ± 1.1	7 ± 0	-112.3
1.1.17.01.	Ammonium transporter Amt-1	2b2f	Archaeoglobus fulgidus	Archaebac.	3	33	28.9 ± 0.7	0 ± 0	-152.5
1.1.26.04.	Glycine betaine transporter BetP, alternative inward-facing open conformation	3p03	Corynebacterium glutamicum	Bact. Gram-pos plas.	3	36	29.8 ± 0.7	1 ± 0	-160.9
1.3.16.02.	Porin	3prn	Rhodopseudomonas blastica	Bact. Gram-neg outer	3	48	23.2 ± 0.5	0 ± 0	-127.6
1.1.11.01.	Protein translocase SecY, mutant with half-plug (TM2a) deletion	2yxq	Methanococcus jannaschii	Archaebac.	3	12	29.2 ± 1.1	6 ± 0	-89.1
1.2.06.01.	Tumor necrosis factor ligand superfamily member 4	2hew	Mus musculus	Eukaryo. plasma	3	0	1.7 ± 0.3	90 ± 0	-7.9
1.1.26.04.	Glycine betaine transporter BetP, asymmetric trimer, conformation 2	4doj	Corynebacterium glutamicum	Bact. Gram-pos plas.	3	36	30.0 ± 0.6	0 ± 0	-186.4
1.3.16.03.	Porin OprP	2o4v	Pseudomonas aeruginosa	Bact. Gram-neg outer	3	48	23.9 ± 1.1	0 ± 0	-129.6
1.2.43.02.	Fusion glycoprotein E1	1rer	Semiliki forest virus	Viral	3	0	2.6 ± 2.0	38 ± 5	-6.5
1.1.28.01.	Multidrug exporter MexB	2v50	Pseudomonas aeruginosa	Bact. Gram-neg inner	3	36	28.6 ± 1.0	0 ± 1	-167.3
1.1.17.01.	Rh-like protein	3b9y	Nitrosomonas europaea	Bact. Gram-neg inner	3	33	29.8 ± 1.3	0 ± 0	-150.1
1.1.61.01.	Microsomal glutathione S-transferase 1	2h8a	Rattus norvegicus	Endoplasm. reticulum	3	12	29.7 ± 0.7	0 ± 1	-47.7
1.1.11.01.	Protein translocase Sec61, complex with ribosome	2wwb	Canis lupus familiaris	Endoplasm. reticulum	3	12	26.3 ± 0.5	13 ± 0	-60.5
1.1.13.01.	Acid-sensing ion channel	2qts	Gallus gallus	Eukaryo. plasma	3	6	36.6 ± 0.9	15 ± 0	-67.8
1.1.65.01.	Concentrative nucleoside transporter	3tij	Vibrio cholerae	Bact. Gram-neg inner	3	27	27.0 ± 0.5	0 ± 0	-155.2
1.1.09.01.	Sodium-potassium pump, E2-Pi state, slightly different conf.	3kdp	Sus scrofa	Eukaryo. plasma	3	12	31.4 ± 1.4	7 ± 0	-95.3
1.1.05.06.	Ni/Fe-hydrogenase complex	4gd3	Escherichia coli	Bact. Gram-neg inner	3	6	27.2 ± 1.4	9 ± 1	-42.4
1.1.01.01.	Bacteriorhodopsin	1m0l	Halobacterium salinarum	Archaebac.	3	21	31.8 ± 1.1	0 ± 1	-121.1
1.1.32.01.	Proton glutamate symport protein, inward-facing state	3kbc	Pyrococcus horikoshii	Archaebac.	3	30	28.1 ± 0.9	0 ± 1	-158.8
1.3.18.01.	Maltoporin	1af6	Escherichia coli	Bact. Gram-neg outer	3	54	25.1 ± 0.7	0 ± 0	-117.9
1.1.11.01.	Protein translocase SecY, closed state	1rhz	Methanococcus jannaschii	Archaebac.	3	12	29.4 ± 1.0	5 ± 0	-89.2
1.3.24.01.	Outer membrane protein TolC	1ek9	Escherichia coli	Bact. Gram-neg outer	3	12	24.6 ± 1.4	0 ± 2	-56.1
1.3.23.01.	Autotransporter Hia, 992-1098	2gr7	Haemophilus influenzae	Bact. Gram-neg outer	3	12	22.7 ± 2.0	0 ± 1	-43.5
1.2.43.01.	Envelope glycoprotein	1urz	Tick-borne encephalitis virus	Viral	3	0	5.9 ± 0.9	1 ± 8	-10.3
1.3.16.01.	Porin B (PorB)	3a2s	Neisseria meningitidis	Bact. Gram-neg outer	3	48	24.4 ± 1.0	0 ± 0	-102.1
1.3.24.01.	Cation efflux system protein CusC	3pik	Escherichia coli	Bact. Gram-neg outer	3	12	24.3 ± 1.2	1 ± 0	-33.8
1.3.23.01.	Adhesin yadA	2lme	Yersinia enterocolitica	Bact. Gram-neg outer	3	15	23.4 ± 2.2	0 ± 1	-37.7
1.1.31.01.	Tellurite resistance protein tehA homolog	3m73	Haemophilus influenzae	Bact. Gram-neg inner	3	30	29.1 ± 1.4	0 ± 0	-157.4
1.1.61.01.	FLAP protein (5-lipoxygenase activator)	2q7r	Homo sapiens	Endoplasm. reticulum	3	12	30.3 ± 1.3	0 ± 1	-70.8
1.1.28.02.	Efflux transporter CusA, complex with CusB	3ne5	Escherichia coli	Bact. Gram-neg inner	3	36	29.0 ± 0.7	0 ± 0	-165.0
1.1.61.01.	Microsomal prostaglandin E synthase 1	3dww	Homo sapiens	Endoplasm. reticulum	3	12	31.9 ± 1.1	2 ± 1	-97.3
1.1.13.02.	ATP-gated P2X4 ion channel, closed state	3h9v	Danio rerio	Eukaryo. plasma	3	6	27.6 ± 1.3	0 ± 1	-61.3
1.1.01.01.	Halorhodopsin	3a7k	Natronomonas pharaonis	Archaebac.	3	21	33.8 ± 1.4	1 ± 0	-141.3
1.2.03.02.	SLAM family member 6	2if7	Homo sapiens	Eukaryo. plasma	3	0	2.0 ± 3.3	88 ± 11	-7.1
1.3.18.01.	Maltoporin	2mpr	Salmonella enterica	Bact. Gram-neg outer	3	54	24.5 ± 1.0	0 ± 0	-109.7
1.1.32.01.	Proton glutamate symport protein, outward-facing state 2	2nww	Pyrococcus horikoshii	Archaebac.	3	36	30.6 ± 0.6	0 ± 0	-200.2
1.3.24.01.	Multidrug Resistance (VceC) protein	1yc9	Vibrio cholerae	Bact. Gram-neg outer	3	12	24.6 ± 1.0	0 ± 0	-62.2
1.1.02.01.	Photosynthetic reaction center, complex with cytochrome c	1eys	Thermochromatium tepidum	Bact. Gram-neg inner	3	11	31.6 ± 1.0	2 ± 0	-116.0
1.3.16.01.	Osmoporin OMPC	3upg	Salmonella typhimurium	Bact. Gram-neg outer	3	48	23.4 ± 0.7	0 ± 0	-118.0
1.1.02.01.	Photosynthetic reaction center	2j8c	Rhodobacter sphaeroides	Bact. Gram-neg inner	3	11	31.8 ± 0.8	2 ± 0	-129.6
1.1.01.01.	Halorhodopsin	1e12	Halobacterium salinarum	Archaebac.	3	21	31.8 ± 1.4	0 ± 1	-126.7
1.1.60.01.	Protease GlpG, crystallographic trimer	4h1d	Escherichia coli	Bact. Gram-neg inner	3	18	27.0 ± 0.1	2 ± 0	-108.7
1.1.11.01.	Protein translocase SecY, mutant with full-plug (TM2a) deletion	2yxr	Methanococcus jannaschii	Archaebac.	3	12	29.7 ± 0.8	4 ± 4	-95.6
1.3.18.01.	Sucrose-specific porin	1a0s	Salmonella enterica	Bact. Gram-neg outer	3	54	23.8 ± 1.1	0 ± 0	-103.5
1.2.06.01.	Spore surface protein Bcla	1wck	Bacillus anthracis	Bact. Gram-pos plas.	3	0	3.3 ± 0.2	8 ± 5	-8.9
1.1.32.01.	Proton glutamate symport protein, mixed inward/outward trimer	3v8g	Pyrococcus horikoshii	Archaebac.	3	30	29.8 ± 1.0	5 ± 0	-169.4
1.3.24.01.	Drug-Discharge Outer Membrane Protein, OprM	1wp1	Pseudomonas aeruginosa	Bact. Gram-neg outer	3	12	24.7 ± 1.2	0 ± 0	-64.0
1.1.17.01.	Ammonia Channel	1u7g	Escherichia coli	Bact. Gram-neg inner	3	33	29.8 ± 1.3	0 ± 0	-148.7
1.1.02.01.	Photosynthetic reaction center, complex with cytochrome c	1l9b	Rhodobacter sphaeroides	Bact. Gram-neg inner	3	11	31.6 ± 0.8	3 ± 0	-127.3
1.3.16.01.	Osmoporin OMPC, isoform 1	2ixx	Escherichia coli	Bact. Gram-neg outer	3	48	26.2 ± 1.3	0 ± 1	-142.5
1.2.43.01.	Envelope protein	3g7t	Dengue virus	Viral	3	0	5.9 ± 0.9	1 ± 3	-12.2
1.1.28.02.	Efflux transporter CusA, apo-protein	3k07	Escherichia coli	Bact. Gram-neg inner	3	33	27.4 ± 1.2	0 ± 0	-166.7
1.1.11.01.	Protein translocase SecY, complex with SecA	3din	Thermotoga maritima	Bact. Gram-neg inner	3	13	26.9 ± 0.1	5 ± 0	-63.3
1.3.20.01.	Fe-regulated protein B	4aip	Neisseria meningitidis	Bact. Gram-neg outer	3	66	23.4 ± 0.3	0 ± 0	-144.6
1.1.02.01.	Photosynthetic reaction center, more complete structure	2j8d	Rhodobacter sphaeroides	Bact. Gram-neg inner	3	11	31.6 ± 1.0	5 ± 0	-135.5
1.1.09.01.	Sodium-potassium pump, E2-Pi state	3b8e	Sus scrofa	Eukaryo. plasma	3	12	30.7 ± 0.9	12 ± 0	-93.6
1.1.17.01.	Rhesus Glycoprotein RhCG	3hd6	Homo sapiens	Eukaryo. plasma	3	36	31.8 ± 0.7	0 ± 0	-174.1
1.1.13.01.	Acid-sensitive ion channel, conformation at low pH	3hgc	Gallus gallus	Eukaryo. plasma	3	6	24.1 ± 0.7	0 ± 0	-37.9
1.1.03.02.	Light-Harvesting Complex II	1rwt	Spinacia oleracea	Thylakoid	3	9	30.0 ± 0.7	0 ± 0	-154.0
1.1.09.01.	Sodium-potassium pump, different conformation	3n23	Sus scrofa	Eukaryo. plasma	3	12	29.9 ± 0.9	6 ± 0	-96.0
1.1.28.01.	Multidrug efflux transporter AcrB, symmetric	3d9b	Escherichia coli	Bact. Gram-neg inner	3	36	28.4 ± 0.6	0 ± 0	-189.9
1.1.11.01.	Protein translocase SecY, complex with ribosome 2	3bo0	Methanococcus jannaschii	Archaebac.	3	12	29.6 ± 1.2	6 ± 2	-78.0
1.1.12.01.	Potassium channel KcsA, 23A opening conformer	3f7v	Streptomyces lividans	Bact. Gram-pos plas.	4	8	30.1 ± 1.1	0 ± 0	-95.2
1.1.12.02.	Potassium channel Kirbac1.1, closed state	1p7b	Burkholderia pseudomallei	Bact. Gram-neg inner	4	12	33.1 ± 1.3	0 ± 0	-111.9
1.2.23.01.	M2 proton channel of Influenza A, closed state, NMR	2rlf	Influenza virus	Viral	4	4	34.3 ± 2.0	3 ± 1	-67.6
1.1.12.02.	Kir3.1-prokaryotic Kir channel chimera	2qks	Burkholderia xenovorans	Bact. Gram-neg inner	4	12	30.5 ± 1.4	0 ± 1	-88.6
1.1.07.01.	Bacterial cytochrome c oxidase, cbb3 type	3mk7	Pseudomonas stutzeri	Bact. Gram-neg inner	4	17	32.8 ± 1.2	4 ± 4	-119.2
1.1.12.01.	Potassium channel Kv1.2.	2a79	Rattus norvegicus	Eukaryo. plasma	4	28	29.8 ± 1.5	0 ± 0	-147.0
1.1.12.01.	Voltage-gated sodium channel NavAb	3rvy	Arcobacter butzleri	Bact. Gram-neg inner	4	24	29.6 ± 0.4	0 ± 0	-216.9
1.1.12.01.	NaK-NavSulP chimera channel	3vou	Sulfitobacter sp.	Bact. Gram-neg inner	4	8	30.4 ± 0.8	0 ± 0	-100.1
1.1.12.01.	NaK potassium channel, closed state	2ahy	Bacillus cereus	Bact. Gram-pos plas.	4	12	29.5 ± 0.7	0 ± 1	-105.7
1.1.12.01.	Potassium channel KcsA, 14.5 A opening conformer	3fb5	Streptomyces lividans	Bact. Gram-pos plas.	4	8	33.7 ± 0.9	0 ± 0	-115.9
1.1.12.01.	Calcium-gated potassium channel MthK	3ldc	Methanobacterium thermoautotrophicum	Archaebac.	4	8	29.8 ± 0.8	0 ± 0	-72.4
1.2.17.01.	Vesicle-associated membrane protein complex	2nps	Mus musculus	Golgi	4	0	5.6 ± 2.2	68 ± 4	-5.6
1.1.07.01.	Bacterial cytochrome c oxidase	1m56	Rhodobacter sphaeroides	Bact. Gram-neg inner	4	22	29.6 ± 1.8	3 ± 0	-173.7
1.1.12.02.	Potassium channel Kir 2.2, complex with inositol lipid	3spg	Gallus gallus	Eukaryo. plasma	4	8	30.8 ± 1.2	0 ± 0	-109.1
1.2.23.01.	M2 proton channel of Influenza A, closed state, V27A mutant	2kwx	Influenza virus	Viral	4	4	33.4 ± 1.9	2 ± 3	-63.4
1.1.14.01.	Aquaporin-1	1h6i	Homo sapiens	Eukaryo. plasma	4	32	30.8 ± 1.1	0 ± 0	-135.6
1.1.16.01.	Glutamate receptor 2	3kg2	Rattus norvegicus	Eukaryo. plasma	4	16	31.8 ± 2.0	0 ± 0	-93.0
1.1.12.01.	Potassium channel KcsA, 16 A opening conformer	3fb6	Streptomyces lividans	Bact. Gram-pos plas.	4	8	30.2 ± 1.0	0 ± 0	-86.1
1.1.07.01.	Bacterial cytochrome c oxidase	1qle	Paracoccus denitrificans	Bact. Gram-neg inner	4	22	31.7 ± 1.3	4 ± 0	-167.4
1.2.23.01.	M2 proton channel of Influenza A, closed state	3lbw	Influenza virus	Viral	4	4	31.1 ± 1.7	7 ± 10	-50.5
1.2.23.01.	M2 proton channel of Influenza B	2kix	Influenza virus	Viral	4	4	31.8 ± 1.2	2 ± 3	-64.4
1.1.12.02.	G protein-activated inward rectifier potassium channel 2, diff. conf.	3syq	Mus musculus	Eukaryo. plasma	4	8	31.6 ± 0.6	0 ± 0	-107.9
1.1.14.01.	Aquaporin-0	2b6o	Ovis aries	Eukaryo. plasma	4	32	31.8 ± 1.4	0 ± 0	-143.3
1.1.14.01.	Aquaporin Sopip2, closed state	1z98	Spinacia oleracea	Eukaryo. plasma	4	32	28.1 ± 2.2	0 ± 0	-117.2
1.1.14.01.	Aquaporin-4, different conformation of loops with lipids	2zz9	Rattus norvegicus	Eukaryo. plasma	4	28	29.5 ± 0.7	0 ± 0	-115.6
1.1.12.01.	Multi-ligand gated K(+) channel, TrkA, mutant	4gx0	Geobacter sulfurreducens	Bact. Gram-neg inner	4	8	31.8 ± 1.3	0 ± 0	-109.5
1.1.12.01.	Potassium channel KcsA, full length, open	3pjs	Streptomyces lividans	Bact. Gram-pos plas.	4	8	31.6 ± 1.2	1 ± 1	-87.3
1.1.12.01.	NaK potassium channel, open state	3e86	Bacillus cereus	Bact. Gram-pos plas.	4	12	27.6 ± 0.9	0 ± 0	-90.0
1.1.12.01.	Potassium channel KcsA, 20 A opening conformer	3fb8	Streptomyces lividans	Bact. Gram-pos plas.	4	8	29.8 ± 0.4	0 ± 0	-68.2
1.1.14.01.	Aquaporin-0, alternative packing with lipids	3m9i	Ovis aries	Eukaryo. plasma	4	24	27.6 ± 1.4	0 ± 0	-139.0
1.2.23.01.	M2 proton channel of Influenza A, complex with amantadine	2kqt	Influenza virus	Viral	4	4	30.2 ± 1.3	0 ± 4	-59.6
1.1.14.01.	Aquaporin Sopip2, closed state 2	3cll	Spinacia oleracea	Eukaryo. plasma	4	27	29.8 ± 0.7	0 ± 0	-127.8
1.1.12.01.	Bacterial cyclic nucleotide regulated ion channel	3beh	Rhizobium loti	Bact. Gram-neg inner	4	28	30.6 ± 0.8	0 ± 0	-205.7
1.1.12.02.	Potassium channel Kirbac1.1, closed state, refined	2wll	Burkholderia pseudomallei	Bact. Gram-neg inner	4	8	33.4 ± 2.4	0 ± 0	-109.1
1.1.14.01.	Aquaporin-1	1j4n	Bos taurus	Eukaryo. plasma	4	32	31.8 ± 1.0	0 ± 0	-129.2
1.1.14.01.	Aquaporin Sopip2, open state	2b5f	Spinacia oleracea	Eukaryo. plasma	4	32	29.4 ± 1.1	2 ± 2	-113.0
1.1.14.01.	Aquaporin-5	3d9s	Homo sapiens	Eukaryo. plasma	4	32	30.3 ± 0.9	0 ± 0	-133.3
1.1.14.01.	Aquaporin AQY1	2w2e	Pichia pastoris	Eukaryo. plasma	4	32	30.2 ± 0.8	0 ± 0	-131.7
1.1.12.02.	Potassium channel Kir 2.2	3jyc	Gallus gallus	Eukaryo. plasma	4	12	30.5 ± 1.4	0 ± 1	-119.9
1.1.12.01.	Multi-ligand gated K(+) channel, TrkA	4gx5	Geobacter sulfurreducens	Bact. Gram-neg inner	4	8	31.6 ± 0.7	0 ± 0	-94.6
1.1.12.01.	Potassium channel KvAP	1orq	Aeropyrum pernix	Archaebac.	4	12	29.3 ± 1.6	0 ± 0	-78.6
1.1.18.01.	Mechanosensitive channel MscL	3hzq	Staphylococcus aureus	Bact. Gram-pos plas.	4	8	20.8 ± 1.2	1 ± 0	-56.9
2.3.04.01.	Pteridine reductase 1	1p33	Leishmania tarentolae (Sauroleishmania tarentolae)	Eukaryo. plasma	4	0	3.4 ± 1.0	73 ± 13	-7.7
1.1.12.01.	Voltage-gated K+ channel	4h33	Listeria monocytogenes	Bact. Gram-pos plas.	4	8	33.2 ± 1.9	0 ± 0	-115.9
1.1.12.01.	Potassium channel KcsA, complex with Rb+	3fb7	Streptomyces lividans	Bact. Gram-pos plas.	4	8	28.6 ± 1.2	0 ± 0	-79.0
1.1.12.02.	Potassium channel Kirbac3.1, closed conformation	2wlk	Magnetospirillum magnetotacticum	Bact. Gram-neg inner	4	8	29.8 ± 2.4	0 ± 0	-78.7
1.1.14.01.	Aquaporin-0	1ymg	Bos taurus	Eukaryo. plasma	4	32	31.3 ± 1.2	0 ± 0	-138.4
1.1.12.02.	Potassium channel Kirbac3.1, open conformation	3zrs	Magnetospirillum magnetotacticum	Bact. Gram-neg inner	4	12	30.0 ± 1.1	0 ± 0	-85.9
1.1.12.01.	Bacterial cyclic nucleotide regulated ion channel, different conformation	2zd9	Rhizobium loti	Bact. Gram-neg inner	4	24	31.6 ± 1.2	0 ± 0	-192.8
1.1.12.01.	Potassium channel KcsA	1r3j	Streptomyces lividans	Bact. Gram-pos plas.	4	12	34.8 ± 1.2	0 ± 0	-111.0
1.1.14.01.	Aquaporin AqpM	3ne2	Archaeoglobus fulgidus	Archaebac.	4	24	31.2 ± 1.3	0 ± 0	-143.5
1.1.12.02.	G protein-activated inward rectifier potassium channel 2 (GIRK2, Kir3.2)	3sya	Mus musculus	Eukaryo. plasma	4	12	34.8 ± 0.7	0 ± 0	-145.5
1.1.14.01.	Aquaporin Z	1rc2	Escherichia coli	Bact. Gram-neg inner	4	32	29.7 ± 1.3	0 ± 0	-118.7
1.2.23.01.	M2 proton channel, influenza A and B hydrid	2ljb	Influenza virus	Viral	4	4	31.6 ± 1.6	1 ± 1	-51.3
1.2.43.01.	Capsid envelop protein complex	3j2p	Dengue virus	Viral	4	8	22.8 ± 0.4	0 ± 0	-62.7
1.1.14.01.	Aquaglyceroporin	3c02	Plasmodium falciparum	Eukaryo. plasma	4	32	30.4 ± 1.3	0 ± 0	-137.4
1.1.12.01.	Potassium channel Kv1.2. - Kv2.1. chimera	3lnm	Rattus norvegicus	Eukaryo. plasma	4	28	31.1 ± 0.9	0 ± 0	-260.7
1.1.01.01.	Sensory rhodopsin II, tetramer	1h2s	Natronomonas pharaonis	Archaebac.	4	18	30.5 ± 1.1	0 ± 0	-123.4
1.1.12.01.	Voltage-gated sodium channel NavAb, different conformation	4ekw	Arcobacter butzleri	Bact. Gram-neg inner	4	24	29.4 ± 0.5	0 ± 0	-201.0
1.1.12.01.	Potassium channel KcsA	1s5h	Streptomyces coelicolor	Bact. Gram-pos plas.	4	12	33.7 ± 1.3	0 ± 1	-111.9
1.1.12.01.	Potassium channel KvAP	2a0l	Aeropyrum pernix	Archaebac.	4	12	29.5 ± 1.1	0 ± 0	-100.0
1.1.12.01.	Potassium channel KcsA, open inactivated state	3f5w	Streptomyces lividans	Bact. Gram-pos plas.	4	8	29.2 ± 0.7	0 ± 0	-83.5
1.1.12.01.	NaK potassium channel, different strain of Bacillus cereus	3ouf	Bacillus cereus	Bact. Gram-pos plas.	4	12	27.9 ± 1.3	0 ± 0	-91.0
1.1.14.01.	Glycerol uptake facilitator	1ldf	Escherichia coli	Bact. Gram-neg inner	4	32	30.1 ± 0.9	0 ± 0	-147.9
1.2.23.01.	M2 proton channel of Influenza A, open state, ligand-free	3bkd	Influenza virus	Viral	4	4	27.1 ± 1.8	3 ± 1	-55.0
1.2.23.01.	M2 proton channel, influenza A and B hydrid, complex with rimantadine	2ljc	Influenza virus	Viral	4	4	30.6 ± 1.8	9 ± 2	-44.9
1.2.23.01.	M2 proton channel of Influenza A, closed state, S31N, with drug	2ly0	Influenza virus	Viral	4	4	34.0 ± 1.6	0 ± 0	-67.5
1.1.14.01.	Aquaporin Z2	3llq	Agrobacterium tumefaciens	Bact. Gram-neg inner	4	32	29.8 ± 0.6	0 ± 0	-134.5
1.1.14.01.	Aquaporin-0, open state	2b6p	Bos taurus	Eukaryo. plasma	4	32	31.1 ± 1.5	0 ± 1	-130.0
1.1.14.01.	Aquaporin-4	2d57	Rattus norvegicus	Eukaryo. plasma	4	32	29.8 ± 1.1	0 ± 0	-126.2
1.1.12.01.	Potassium channel Kv1.2 - Kv2.1. chimera, in membrane-like environment	2r9r	Rattus norvegicus	Eukaryo. plasma	4	28	30.8 ± 0.6	0 ± 0	-252.0
1.1.12.01.	Potassium channel Kv1.2., full-length	3lut	Rattus norvegicus	Eukaryo. plasma	4	24	25.1 ± 0.5	0 ± 0	-153.1
1.1.14.01.	Aquaporin AqpM	2f2b	Methanobacterium thermoautotrophicum	Archaebac.	4	32	29.0 ± 0.8	0 ± 0	-129.9
1.1.12.01.	Potassium channel KcsA, full-length, closed	3eff	Streptomyces lividans	Bact. Gram-pos plas.	4	12	31.8 ± 1.3	0 ± 0	-107.3
1.1.12.01.	Potassium channel KscA, complex with charibdotoxin	2a9h	Streptomyces lividans	Bact. Gram-pos plas.	4	8	31.8 ± 1.4	0 ± 1	-105.1
1.2.23.01.	M2 proton channel of Influenza A, open state, complex with amantadine	3c9j	Influenza virus	Viral	4	4	29.4 ± 1.4	2 ± 3	-65.6
1.1.12.02.	Potassium channel Kir 2.2, complex with pyrophosphate lipid	3spc	Gallus gallus	Eukaryo. plasma	4	8	30.6 ± 1.2	0 ± 0	-120.3
1.1.14.01.	Aquaporin-4	3gd8	Homo sapiens	Eukaryo. plasma	4	32	29.8 ± 1.1	0 ± 1	-122.9
1.1.12.01.	Voltage gated sodium channel, open conformation	4f4l	Magnetococcus marinus	Bact. Gram-neg inner	4	8	28.2 ± 1.3	1 ± 0	-74.6
1.1.12.01.	Potassium channel KcsA, 17A opening conformer	3f7y	Streptomyces lividans	Bact. Gram-pos plas.	4	8	31.3 ± 1.3	0 ± 0	-82.3
1.1.21.01.	Magnesium transport protein CorA	4ev6	Methanococcus jannaschii	Archaebac.	5	10	28.4 ± 1.5	0 ± 1	-92.4
1.1.14.02.	Formate transporter 1, FocA	3kcu	Escherichia coli	Bact. Gram-neg inner	5	35	29.9 ± 0.7	0 ± 0	-160.9
1.1.15.01.	Nicotinic acetylcholine receptor, partially open state	4aq9	Torpedo marmorata	Eukaryo. plasma	5	20	30.8 ± 0.8	2 ± 0	-109.5
1.1.14.02.	Formate/nitrite transporter	3tdp	Clostridium difficile	Bact. Gram-pos plas.	5	30	28.4 ± 1.9	0 ± 0	-161.3
1.2.25.01.	Phospholamban	1zll	Homo sapiens	Endoplasm. reticulum	5	5	30.5 ± 1.4	0 ± 2	-76.0
1.1.14.02.	Formate transporter	3q7k	Salmonella enterica	Bact. Gram-neg inner	5	30	28.6 ± 0.0	0 ± 0	-148.8
1.2.17.01.	Complexin/SNARE complex	1kil	Rattus norvegicus	Eukaryo. plasma	5	0	4.0 ± 2.0	15 ± 14	-3.4
1.1.21.01.	CorA magnesium transporter, conformation 1	2bbj	Thermotoga maritima	Bact. Gram-neg inner	5	10	29.9 ± 1.0	0 ± 0	-80.8
1.1.15.02.	Proton-gated ion channel, different conformation	4a97	Erwinia chrysanthemi	Bact. Gram-neg inner	5	40	31.8 ± 0.5	0 ± 0	-125.8
1.1.21.01.	CorA magnesium transporter, complete loops	4i0u	Thermotoga maritima	Bact. Gram-neg inner	5	10	30.4 ± 1.1	0 ± 0	-83.4
1.1.15.02.	Proton-gated ion channel, inactive, complex with acetylcholine	3rqw	Erwinia chrysanthemi	Bact. Gram-neg inner	5	20	29.8 ± 0.4	0 ± 0	-118.8
1.1.15.02.	Proton-gated ion channel, open state	3eam	Gloeobacter violaceus	Bact. Gram-neg inner	5	20	32.7 ± 0.9	0 ± 1	-183.4
1.1.62.01.	Diguanylate cyclase/phosphodiesterase	3pjv	Pseudomonas fluorescens	Bact. Gram-neg inner	5	0	4.6 ± 1.5	79 ± 4	-6.6
1.1.15.01.	Glutamate-gated chloride channel GluCl alpha	3rhw	Caenorhabditis elegans	Eukaryo. plasma	5	20	30.2 ± 0.7	0 ± 0	-107.9
1.1.18.01.	Mechanosensitive channel MscL	2oar	Mycobacterium tuberculosis	Bact. Gram-pos plas.	5	10	36.1 ± 2.2	0 ± 0	-142.7
1.1.15.02.	Proton-gated ion channel, inactive conformation	2vl0	Erwinia chrysanthemi	Bact. Gram-neg inner	5	20	31.8 ± 1.3	0 ± 0	-107.6
1.1.21.01.	CorA magnesium transporter, conformation 2	4eeb	Thermotoga maritima	Bact. Gram-neg inner	5	10	30.0 ± 1.0	1 ± 1	-81.6
1.1.15.01.	Nicotinic acetylcholine receptor, closed state	2bg9	Torpedo marmorata	Eukaryo. plasma	5	20	30.1 ± 1.1	3 ± 0	-119.6
1.1.14.02.	Nitrite transporter NirC	4fc4	Salmonella typhimurium	Bact. Gram-neg inner	5	35	33.8 ± 0.0	0 ± 0	-112.5
1.1.15.02.	Proton-gated ion channel, locally closed	3tlw	Gloeobacter violaceus	Bact. Gram-neg inner	5	20	34.0 ± 1.6	0 ± 0	-190.3
1.1.14.02.	Formate transporter 1, FocA	3kly	Vibrio cholerae	Bact. Gram-neg inner	5	35	31.4 ± 0.5	1 ± 0	-188.2
1.1.15.02.	Proton-gated ion channel, different inactive conformation	3uq7	Erwinia chrysanthemi	Bact. Gram-neg inner	5	20	32.0 ± 1.6	0 ± 1	-92.6
1.1.21.01.	CorA magnesium transporter, conformation 3	2iub	Thermotoga maritima	Bact. Gram-neg inner	5	10	28.0 ± 1.2	0 ± 0	-65.7
1.1.74.01.	Calcium release-activated calcium channel protein 1	4hkr	Drosophila melanogaster	Eukaryo. plasma	6	24	30.0 ± 1.6	0 ± 0	-105.2
1.1.49.01.	ATP-dependent zinc metalloprotease FtsH	3kds	Thermotoga maritima	Bact. Gram-neg inner	6	0	2.2 ± 0.4	90 ± 0	-12.8
1.1.20.01.	Connexin 26 gap junction channel (beta-2 protein)	2zw3	Spodoptera frugiperda	Eukaryo. plasma	6	24	32.2 ± 0.5	0 ± 0	-155.9
1.1.76.01.	Acid-activated urea channel	3ux4	Helicobacter pylori	Bact. Gram-neg inner	6	36	30.0 ± 0.5	0 ± 0	-190.2
1.1.28.01.	Multidrug efflux transporter AcrB with YajC subunit , symmetric	2rdd	Escherichia coli	Bact. Gram-neg inner	6	39	28.4 ± 0.5	0 ± 0	-156.2
1.1.05.02.	Formate dehydrogenase	1kqf	Escherichia coli	Bact. Gram-neg inner	6	15	33.7 ± 1.1	0 ± 0	-141.9
1.1.06.01.	Cytochrome bc1, bacterial	1zrt	Rhodobacter capsulatus	Bact. Gram-neg inner	6	20	29.9 ± 0.9	0 ± 0	-178.6
1.2.01.01.	Fibroblast growth factor receptor 2 complex	3oj2	Homo sapiens	Secreted	6	0	2.0 ± 0.4	81 ± 3	-5.4
1.1.06.01.	Cytochrome bc1, bacterial	2qjy	Rhodobacter sphaeroides	Bact. Gram-neg inner	6	20	30.2 ± 0.6	0 ± 0	-188.6
1.1.06.01.	Cytochrome bc1, bacterial	2yiu	Paracoccus denitrificans	Bact. Gram-neg inner	6	20	29.8 ± 0.5	0 ± 0	-188.8
1.1.04.01.	Respiratory complex I	3rko	Escherichia coli	Bact. Gram-neg inner	6	58	29.6 ± 0.0	9 ± 0	-236.7
1.1.05.05.	Succinate dehydrogenase	1nek	Escherichia coli	Bact. Gram-neg inner	6	18	32.0 ± 0.6	0 ± 0	-183.5
1.1.04.01.	Respiratory complex I	4hea	Thermus thermophilus	Bact. Gram-neg inner	7	67	29.8 ± 0.5	10 ± 0	-299.7
1.1.59.01.	ATP-dependent Clp protease proteolytic subunit 1	2cby	Mycobacterium tuberculosis	Bact. Gram-pos plas.	7	0	3.2 ± 0.0	89 ± 0	-17.0
1.3.25.01.	Alpha-hemolysin	7ahl	Staphylococcus aureus	Secreted	7	14	23.5 ± 0.9	0 ± 1	-49.3
2.3.04.01.	Tropinone reductase 2	1ipe	Datura stramonium (Jimsonweed)	Eukaryo. plasma	7	0	3.3 ± 0.7	77 ± 4	-8.8
1.1.19.01.	Mechanosensitive channel protein MscS, expanded state	2oau	Escherichia coli	Bact. Gram-neg inner	7	14	31.8 ± 0.8	1 ± 1	-171.3
1.1.19.01.	Mechanosensitive channel protein MscS	3t9n	Thermoanaerobacter tengcongensis	Bact. Gram-pos plas.	7	7	28.0 ± 0.7	0 ± 0	-131.5
1.1.19.01.	Mechanosensitive channel protein MscS, open state	2vv5	Escherichia coli	Bact. Gram-neg inner	7	21	27.8 ± 1.9	0 ± 0	-138.7
1.3.25.01.	Necrotic enteritis toxin B, NetB	4h56	Clostridium perfringens	Secreted	7	17	25.2 ± 0.8	0 ± 0	-50.7
1.1.19.01.	Mechanosensitive channel protein MscS, closed state	4hw9	Helicobacter pylori	Bact. Gram-neg inner	7	14	31.6 ± 1.8	0 ± 0	-140.9
1.1.19.01.	Mechanosensitive channel protein MscS, slightly different conf.	3udc	Thermoanaerobacter tengcongensis	Bact. Gram-pos plas.	7	7	32.2 ± 0.7	0 ± 0	-121.8
1.1.39.03.	Energy-coupling factor transporter EcfA, conformation 2	4huq	Bacillus brevis	Bact. Gram-pos plas.	7	7	29.8 ± 0.7	14 ± 0	-76.0
1.3.25.02.	Cytolysin and hemolysin HlyA Pore-forming toxin	3o44	Vibrio cholerae	Secreted	7	14	24.6 ± 0.0	0 ± 0	-33.1
1.3.25.01.	Gamma-hemolysin, complete channel, hetero-octamer	3b07	Staphylococcus aureus	Secreted	8	16	21.4 ± 1.0	0 ± 0	-32.8
1.3.26.01.	Porin MspA	1uun	Mycobacterium smegmatis	Bact. Gram-pos cell wall	8	16	40.7 ± 2.1	0 ± 0	-71.0
1.2.26.01.	Outer membrane lipoprotein Wza	2j58	Escherichia coli	Bact. Gram-neg outer	8	8	31.1 ± 0.8	0 ± 0	-123.8
1.2.43.01.	E1/E2 envelope glycoprotein complex	2yew	Barmah forest virus	Viral	8	8	30.0 ± 0.8	0 ± 0	-53.5
1.2.26.01.	Outer membrane lipoprotein Wza, water-soluble part	2w8h	Escherichia coli	Bact. Gram-neg outer	8	0	1.6 ± 0.2	1 ± 0	-22.1
1.2.43.01.	E1/E2 envelope glycoprotein complex	3j2w	Chikungunya virus	Viral	8	8	30.8 ± 0.9	2 ± 0	-134.1
1.1.75.02.	Sec-independent protein translocase TatA, nonamer model	2lzs	Escherichia coli	Bact. Gram-neg inner	9	9	29.2 ± 1.8	26 ± 2	-29.1
1.1.02.02.	Photosystem I	1jb0	Thermosynechococcus elongatus	Thylakoid	9	32	31.4 ± 0.4	1 ± 0	-285.7
1.1.55.01.	Bacterial polysaccharide co-polymerase FepE	3b8n	Escherichia coli	Bact. Gram-neg inner	9	0	1.6 ± 0.1	1 ± 0	-20.3
1.1.50.01.	Particulate methane monooxygenase, different structure	3rgb	Methylococcus capsulatus	Bact. Gram-neg inner	9	39	28.2 ± 0.6	0 ± 0	-204.9
1.1.50.01.	Particulate methane monooxygenase	1yew	Methylococcus capsulatus	Bact. Gram-neg inner	9	42	28.2 ± 0.7	0 ± 0	-188.5
1.1.06.01.	Cytochrome bc1, mitochondrial, different structure of complex 3	2a06	Bos taurus	Mitochon. inner	9	23	29.8 ± 0.3	2 ± 0	-166.2
1.1.06.01.	Cytochrome bc1, mitochondrial	3h1j	Gallus gallus	Mitochon. inner	10	24	28.2 ± 0.6	0 ± 0	-184.8
1.1.08.01.	F1F0 ATP synthase, F0F1 complex, different conformation	3zry	Saccharomyces cerevisiae	Mitochon. inner	10	20	33.6 ± 1.9	4 ± 0	-56.0
1.1.50.01.	Particulate methane monooxygenase	3rfr	Methylocystis sp.	Bact. Gram-neg inner	10	39	29.8 ± 0.5	0 ± 0	-198.1
1.1.06.01.	Cytochrome bc1, mitochondrial, different structure of complex 2	1pp9	Bos taurus	Mitochon. inner	10	26	29.8 ± 0.3	6 ± 0	-179.3
1.1.08.01.	F1F0 ATP synthase, F0 complex	4f4s	Saccharomyces cerevisiae	Mitochon. inner	10	20	38.4 ± 1.3	0 ± 0	-89.9
1.2.11.01.	Capsid protein G8P	1ifl	Bacteriophage IKe	Secreted	10	10	30.8 ± 0.8	0 ± 0	-93.6
1.1.08.01.	F1F0 ATP synthase, F0F1 complex, more complete model	4b2q	Saccharomyces cerevisiae	Mitochon. inner	10	20	38.4 ± 0.9	0 ± 0	-115.7
1.1.08.01.	F1F0 ATP synthase, F0F1 complex	2xok	Saccharomyces cerevisiae	Mitochon. inner	10	20	35.3 ± 1.3	0 ± 0	-58.9
1.1.50.01.	Particulate methane monooxygenase	3chx	Methylosinus trichosporium	Bact. Gram-neg inner	10	30	29.8 ± 0.4	0 ± 0	-152.0
1.3.07.01.	Plasminogen activator PLA (coagulase/fibrinolysin), disordered loop	2x4m	Yersinia pestis	Bact. Gram-neg outer	10	10	24.2 ± 1.6	2 ± 2	-46.1
1.1.08.01.	V-type Sodium ATPase	2bl2	Enterococcus hirae	Bact. Gram-neg inner	10	40	35.6 ± 0.7	0 ± 0	-189.6
1.1.06.01.	Cytochrome bc1, mitochondrial	3cx5	Saccharomyces cerevisiae	Mitochon. inner	10	24	27.2 ± 0.6	0 ± 0	-173.9
1.1.08.01.	F-type Sodium ATPase	1yce	Ilyobacter tartaricus	Bact. Gram-neg inner	11	22	37.0 ± 0.5	0 ± 0	-104.0
1.1.02.02.	Photosystem I	3lw5	Pisum sativum	Thylakoid	11	46	29.8 ± 0.1	2 ± 0	-311.1
1.1.08.01.	F1F0 ATP synthase, F0 complex, conformation 2	3zo6	Bacillus pseudofirmus	Bact. Gram-pos plas.	12	24	39.6 ± 1.1	1 ± 0	-130.6
1.1.22.01.	Pore-forming haemolysin E (HlyE)	2wcd	Escherichia coli	Secreted	12	36	30.8 ± 0.7	0 ± 0	-148.3
1.2.11.02.	Capsid protein G8P	2ifo	Bacteriophage Xf	Secreted	12	12	32.2 ± 1.9	16 ± 3	-58.4
1.2.11.02.	Capsid protein G8P	1ql1	Bacteriophage Pf1	Secreted	12	12	31.1 ± 1.6	10 ± 0	-55.9
1.1.06.01.	Cytochrome bc1, mitochondrial	1l0l	Bos taurus	Mitochon. inner	12	26	30.0 ± 0.6	0 ± 0	-186.6
1.2.11.02.	Capsid protein G8P	1ifp	Bacteriophage Pf3	Secreted	12	12	34.2 ± 0.1	6 ± 6	-57.6
1.1.06.01.	Cytochrome bc1, mitochondrial, different structure of complex 1	2fyu	Bos taurus	Mitochon. inner	12	26	29.8 ± 0.5	0 ± 0	-182.9
1.1.08.01.	F1F0 ATP synthase, F0 complex	1c17	Escherichia coli	Bact. Gram-neg inner	13	28	34.6 ± 1.2	4 ± 0	-149.9
1.1.08.01.	F1F0 ATP synthase, F0 complex, conformation 1	2x2v	Bacillus pseudofirmus	Bact. Gram-pos plas.	13	26	35.3 ± 1.2	0 ± 0	-137.7
1.1.08.01.	ATP synthase of chloroplast	2w5j	Spinacia oleracea	Thylakoid	14	28	32.8 ± 0.7	0 ± 0	-116.3
1.1.73.01.	Outer membrane complex of type IV secretion system (VirB7/VirB9/VirB10 complex)	3jqo	Escherichia coli	Bact. Gram-neg outer	14	14	22.6 ± 0.6	0 ± 0	-67.4
1.1.08.01.	ATP synthase of chloroplast	3v3c	Pisum sativum	Thylakoid	14	28	32.0 ± 1.0	0 ± 0	-111.5
1.1.08.01.	F1F0 ATP synthase, F0 complex	2xqu	Arthrospira platensis	Thylakoid	15	30	31.8 ± 0.8	0 ± 0	-129.7
1.2.11.01.	Capsid protein G8P	1ifi	Bacteriophage fd	Secreted	15	15	36.8 ± 0.2	0 ± 0	-69.8
1.2.11.01.	Capsid protein G8P	1ifk	Bacteriophage If1	Secreted	15	15	31.8 ± 0.7	0 ± 0	-83.5
1.2.11.02.	Capsid protein G8P	1hgz	Bacteriophage PH75	Secreted	15	15	29.2 ± 2.3	8 ± 7	-46.5
1.1.06.01.	Cytochrome b6f	1q90	Chlamydomonas reinhardtii	Thylakoid	16	26	31.8 ± 1.0	0 ± 1	-226.4
1.1.06.01.	Cytochrome b6f, slightly different structure 1	2d2c	Mastigocladus laminosus	Thylakoid	16	26	28.6 ± 0.6	0 ± 0	-156.9
1.1.02.03.	Photosystem II, monomeric form	3kzi	Thermosynechococcus elongatus	Thylakoid	16	36	31.8 ± 0.5	0 ± 0	-310.1
1.1.06.01.	Cytochrome b6f, slightly different structure 2	4h13	Mastigocladus laminosus	Thylakoid	16	26	31.6 ± 0.6	0 ± 0	219.6
1.3.16.04.	Porin B	4gey	Pseudomonas putida	Bact. Gram-neg outer	16	1	24.2 ± 1.6	6 ± 2	-61.3
1.1.06.01.	Cytochrome b6f	2e74	Mastigocladus laminosus	Thylakoid	16	26	31.2 ± 0.8	0 ± 0	-222.1
1.1.06.01.	Cytochrome b6f	2zt9	Nostoc sp.	Thylakoid	16	26	31.2 ± 1.0	0 ± 1	-214.2
1.1.03.01.	Light-harvesting complex	1lgh	Rhodospirillum molischianum	Bact. Gram-neg inner	16	16	29.7 ± 0.5	0 ± 0	-163.4
1.1.03.01.	Light-harvesting complex LH2	1nkz	Rhodopseudomonas acidophila	Bact. Gram-neg inner	18	18	31.8 ± 0.6	0 ± 0	-193.5
1.1.03.01.	Light-harvesting complex LH3	1ijd	Rhodopseudomonas acidophila	Bact. Gram-neg inner	18	18	29.8 ± 0.7	0 ± 0	-174.6
1.2.12.01.	Fimbrial protein, type IV pilin, assembly	2hil	Neisseria gonorrhoeae	Bact. Gram-neg inner	18	1	29.6 ± 3.0	13 ± 1	-15.9
1.1.07.01.	Mitochondrial cytochrome c oxidase	1v55	Bos taurus	Mitochon. inner	20	56	27.8 ± 0.9	0 ± 0	-209.1
1.1.07.01.	EM model of mitochondrial supercomplex	2ybb	Bos taurus	Mitochon. inner	26	115	30.0 ± 0.3	9 ± 0	-310.3
1.1.02.02.	Photosystem I, trimeric complex	3pcq	Thermosynechococcus elongatus	Thylakoid	27	96	29.8 ± 0.8	0 ± 0	-429.6
1.1.02.03.	Photosystem II	3arc	Thermosynechococcus vulcanus	Thylakoid	32	70	31.8 ± 0.0	0 ± 0	-406.5
1.1.02.03.	Photosystem II	3a0b	Thermosynechococcus vulcanus	Thylakoid	34	72	31.8 ± 0.4	0 ± 0	-397.1
1.1.02.03.	Photosystem II	3bz1	Thermosynechococcus elongatus	Thylakoid	34	72	31.6 ± 0.4	0 ± 0	-409.7