Family » 1.1.14.01. Major intrinsic protein (MIP) family <a href="http://www.tcdb.org/tcdb/index.php?tc=1.A.8" class="external" target="_blank">1.A.8 (TCDB)</a> <a href="http://pfam.sanger.ac.uk/family/PF00230" class="external" target="_blank">PF00230</a>, <a href="http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPfamStr.pl?pfam_id=PF00230" class="external" target="_blank">PDBsum</a> - Orientations of Proteins in Membranes (OPM) database

Type:1. Transmembrane (3 classes)
Class:1.1. Alpha-helical polytopic (72 superfamilies)
Superfamily:1.1.14. Major Intrinsic Protein (MIP)/FNT superfamily (2 families) 1.A.8 (TCDB)
Family:
1.1.14.01. Major intrinsic protein (MIP) family 1.A.8 (TCDB) PF00230, PDBsum

Aquaglyceroporin

Plasmodium falciparum (3c02)

Aquaporin AqpM

Methanobacterium thermoautotrophicum (2f2b, 2evu)
Archaeoglobus fulgidus (3ne2)

Aquaporin AQY1

Pichia pastoris (2w2e, 2w1p)

Aquaporin Sopip2, closed state

Spinacia oleracea (1z98, 3cn6)

Aquaporin Sopip2, closed state 2

Spinacia oleracea (3cll, 3cn5)

Aquaporin Sopip2, open state

Spinacia oleracea (2b5f)

Aquaporin Z

Escherichia coli (1rc2, 2abm, 2o9d, 2o9e, 2o9f, 2o9g, 3nk5, 3nka, 3nkc)

Aquaporin Z2

Agrobacterium tumefaciens (3llq)

Aquaporin-0

Ovis aries (2b6o, 1sor)
Bos taurus (1ymg, 2b6p, 2c32)

Aquaporin-0, alternative packing with lipids

Ovis aries (3m9i)

Aquaporin-0, open state

Bos taurus (2b6p)

Aquaporin-1

Bos taurus (1j4n)
Homo sapiens (1h6i, 1fqy, 1ih5)

Aquaporin-4

Rattus norvegicus (2d57, 3iyz)
Homo sapiens (3gd8)

Aquaporin-4, different conformation of loops with lipids

Rattus norvegicus (2zz9)

Aquaporin-5

Homo sapiens (3d9s)

Glycerol uptake facilitator

Escherichia coli (1ldf, 1fx8, 1lda, 1ldi)

1.1.14.01. Major intrinsic protein (MIP) family 1.A.8 (TCDB) PF00230, PDBsum (20 proteins)

Protein Name	PDB ID	Species	Localization	Num. Subunits	Num. TM Sec. Structs.	Hydrophobic Thickness or Depth (Å)	Tilt Angle (°)	ΔG_transfer (kcal/mol)
Aquaglyceroporin	3c02	Plasmodium falciparum	Eukaryo. plasma	4	32	30.4 ± 1.3	0 ± 0	-137.4
Aquaporin AqpM	2f2b	Methanobacterium thermoautotrophicum	Archaebac.	4	32	29.0 ± 0.8	0 ± 0	-129.9
Aquaporin AqpM	3ne2	Archaeoglobus fulgidus	Archaebac.	4	24	31.2 ± 1.3	0 ± 0	-143.5
Aquaporin AQY1	2w2e	Pichia pastoris	Eukaryo. plasma	4	32	30.2 ± 0.8	0 ± 0	-131.7
Aquaporin Sopip2, closed state	1z98	Spinacia oleracea	Eukaryo. plasma	4	32	28.1 ± 2.2	0 ± 0	-117.2
Aquaporin Sopip2, closed state 2	3cll	Spinacia oleracea	Eukaryo. plasma	4	27	29.8 ± 0.7	0 ± 0	-127.8
Aquaporin Sopip2, open state	2b5f	Spinacia oleracea	Eukaryo. plasma	4	32	29.4 ± 1.1	2 ± 2	-113.0
Aquaporin Z	1rc2	Escherichia coli	Bact. Gram-neg inner	4	32	29.7 ± 1.3	0 ± 0	-118.7
Aquaporin Z2	3llq	Agrobacterium tumefaciens	Bact. Gram-neg inner	4	32	29.8 ± 0.6	0 ± 0	-134.5
Aquaporin-0	1ymg	Bos taurus	Eukaryo. plasma	4	32	31.3 ± 1.2	0 ± 0	-138.4
Aquaporin-0	2b6o	Ovis aries	Eukaryo. plasma	4	32	31.8 ± 1.4	0 ± 0	-143.3
Aquaporin-0, alternative packing with lipids	3m9i	Ovis aries	Eukaryo. plasma	4	24	27.6 ± 1.4	0 ± 0	-139.0
Aquaporin-0, open state	2b6p	Bos taurus	Eukaryo. plasma	4	32	31.1 ± 1.5	0 ± 1	-130.0
Aquaporin-1	1h6i	Homo sapiens	Eukaryo. plasma	4	32	30.8 ± 1.1	0 ± 0	-135.6
Aquaporin-1	1j4n	Bos taurus	Eukaryo. plasma	4	32	31.8 ± 1.0	0 ± 0	-129.2
Aquaporin-4	2d57	Rattus norvegicus	Eukaryo. plasma	4	32	29.8 ± 1.1	0 ± 0	-126.2
Aquaporin-4	3gd8	Homo sapiens	Eukaryo. plasma	4	32	29.8 ± 1.1	0 ± 1	-122.9
Aquaporin-4, different conformation of loops with lipids	2zz9	Rattus norvegicus	Eukaryo. plasma	4	28	29.5 ± 0.7	0 ± 0	-115.6
Aquaporin-5	3d9s	Homo sapiens	Eukaryo. plasma	4	32	30.3 ± 0.9	0 ± 0	-133.3
Glycerol uptake facilitator	1ldf	Escherichia coli	Bact. Gram-neg inner	4	32	30.1 ± 0.9	0 ± 0	-147.9