PDB ID or protein name
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1.2.23.01. Influenza virus matrix protein 2 1.A.19 (TCDB) PF00599, PDBsum (15 proteins)

Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
M2 proton channel of Influenza A, closed state 3lbw Influenza virus Viral 4 4 31.1 ± 1.7 7 ± 10 -50.5
M2 proton channel of Influenza A, closed state, NMR 2rlf Influenza virus Viral 4 4 34.3 ± 2.0 3 ± 1 -67.6
M2 proton channel of Influenza A, closed state, S31N, with drug 2ly0 Influenza virus Viral 4 4 34.0 ± 1.6 0 ± 0 -67.5
M2 proton channel of Influenza A, closed state, V27A mutant 2kwx Influenza virus Viral 4 4 33.4 ± 1.9 2 ± 3 -63.4
M2 proton channel of Influenza A, complex with amantadine 2kqt Influenza virus Viral 4 4 30.2 ± 1.3 0 ± 4 -59.6
M2 proton channel of Influenza A, drug-bound 2muv Influenza virus Viral 4 4 32.4 ± 1.1 0 ± 0 -59.2
M2 proton channel of Influenza A, inward-open state 5um1 Influenza virus Viral 4 4 28.6 ± 1.6 0 ± 0 -55.1
M2 proton channel of Influenza A, monomer 4rwb Influenza virus Viral 1 1 31.6 ± 4.5 46 ± 6 -25.4
M2 proton channel of Influenza A, open state, complex with amantadine 3c9j Influenza virus Viral 4 4 29.4 ± 1.4 2 ± 3 -65.6
M2 proton channel of Influenza A, open state, ligand-free 4qkm Influenza virus Viral 4 4 28.4 ± 1.7 0 ± 0 -55.4
M2 proton channel of Influenza A, S31N, crystal structure 5c02 Influenza virus Viral 4 4 28.6 ± 1.9 0 ± 0 -53.5
M2 proton channel of Influenza A, S31N, NMR structure 2n70 Influenza virus Viral 4 4 29.8 ± 1.7 1 ± 0 -65.3
M2 proton channel of Influenza B 2kix Influenza virus Viral 4 4 31.8 ± 1.2 2 ± 3 -64.4
M2 proton channel, influenza A and B hydrid 2ljb Influenza virus Viral 4 4 31.6 ± 1.6 1 ± 1 -51.3
M2 proton channel, influenza A and B hydrid, complex with rimantadine 2ljc Influenza virus Viral 4 4 30.6 ± 1.8 9 ± 2 -44.9