PDB ID or protein name
See list of these PDB codes

1.2.01.01. Protein tyrosine kinases PF07714, PDBsum (25 proteins)

Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
Epidermal growth factor receptor, erbB-1, homodimer (634-676) 5lv6 Homo sapiens Eukaryo. plasma 2 2 32.4 ± 1.4 1 ± 0 -48.8
Epidermal growth factor receptor, erbB-1, homodimer (634-677) 2m0b Homo sapiens Eukaryo. plasma 2 2 31.8 ± 2.5 15 ± 2 -40.8
Epidermal growth factor receptor, erbB-1, homodimer (642-697) 2m20 Homo sapiens Eukaryo. plasma 2 2 34.0 ± 3.0 0 ± 3 -52.5
Fibroblast growth factor receptor 2 complex 3oj2 Homo sapiens Secreted 6 0 2.0 ± 0.4 81 ± 3 -5.4
Fibroblast growth factor receptor 3, peptide 357-399 2lzl Homo sapiens Eukaryo. plasma 2 2 30.0 ± 4.2 1 ± 3 -28.8
Focal adhesion kinase 1 2j0k Gallus gallus Eukaryo. plasma 1 0 5.0 ± 2.1 36 ± 2 -4.1
High affinity nerve growth factor receptor, NTRK1 2n90 Homo sapiens Eukaryo. plasma 2 2 28.8 ± 2.2 11 ± 7 -29.8
Insulin receptor, peptide 938-988 2mfr Homo sapiens Eukaryo. plasma 1 1 29.8 ± 4.8 41 ± 1 -29.2
Insulin-like growth factor 1 receptor 1p4o Homo sapiens Eukaryo. plasma 1 0 2.4 ± 1.0 37 ± 11 -5.1
Macrophage colony-stimulating factor 1 receptor 3bea Homo sapiens Eukaryo. plasma 1 0 2.9 ± 1.5 54 ± 19 -4.2
Platelet-derived growth factor receptor beta, 526-563 2l6w Homo sapiens Eukaryo. plasma 2 2 34.8 ± 0.8 18 ± 1 -40.9
Receptor tyrosine kinase EphA1, at pH 4.3 2k1k Homo sapiens Eukaryo. plasma 2 2 30.2 ± 1.5 0 ± 5 -43.3
Receptor tyrosine kinase EphA1, at pH 6.3 2k1l Homo sapiens Eukaryo. plasma 2 2 28.8 ± 1.2 5 ± 3 -42.3
Receptor tyrosine kinase EphA2 2k9y Homo sapiens Eukaryo. plasma 2 2 31.8 ± 3.2 12 ± 14 -32.1
Receptor tyrosine kinase erbB-2 1iij Rattus norvegicus Eukaryo. plasma 1 1 31.8 ± 2.8 27 ± 2 -31.8
Receptor tyrosine kinase erbB-2, complex with EGF receptor erbB-1 2ks1 Homo sapiens Eukaryo. plasma 2 2 32.0 ± 2.5 15 ± 5 -50.6
Receptor tyrosine kinase erbB-2, dimer, structure 1 2jwa Homo sapiens Eukaryo. plasma 2 2 31.9 ± 2.9 13 ± 9 -46.6
Receptor tyrosine kinase erbB-2, dimer, structure 2 2n2a Homo sapiens Eukaryo. plasma 2 2 35.0 ± 3.6 14 ± 2 -38.3
Receptor tyrosine-protein kinase erbB-2 1n8y Rattus norvegicus Eukaryo. plasma 1 0 3.4 ± 3.0 53 ± 5 -4.2
Receptor tyrosine-protein kinase erbB-3, extracellular domains 1m6b Homo sapiens Eukaryo. plasma 1 0 2.0 ± 1.6 45 ± 5 -3.9
Receptor tyrosine-protein kinase erbB-3, peptide 640-670 2l9u Homo sapiens Eukaryo. plasma 2 2 33.8 ± 2.4 16 ± 5 -44.6
Receptor tyrosine-protein kinase erbB-4, peptide 642-685 2l2t Homo sapiens Eukaryo. plasma 2 2 32.4 ± 1.5 4 ± 2 -50.4
Vascular endothelial growth factor receptor 2 (759-795), homodimer 1 2m59 Homo sapiens Eukaryo. plasma 2 2 31.8 ± 1.2 2 ± 2 -47.7
Vascular endothelial growth factor receptor 2 (759-795), homodimer 2 2meu Homo sapiens Eukaryo. plasma 2 2 32.0 ± 1.7 0 ± 2 -24.7
Vascular endothelial growth factor receptor 2 (759-795), homotrimer 2met Homo sapiens Eukaryo. plasma 3 3 31.8 ± 1.5 1 ± 1 -331.1