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PDB ID or protein name
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LIPID COMPOSITION ATLAS
Protein Classification
Types
(3 types)
Classes
(11 classes)
Superfamilies
(393 superfamilies)
Families
(668 families)
Species
(539 species)
Localization
(24 types)
All proteins in OPM
(2185 proteins)
Protein Links
PDB Sum
,
PDB
,
OCA
,
MPKS
,
PDBTM
,
MPDB
,
CGDB
Type:
2. Monotopic/peripheral
(4 classes)
Class:
2.2. All beta monotopic/peripheral
(57 superfamilies)
Superfamily:
2.2.41. Defensin-like
(5 families)
Family:
2.2.41.01. Vertebrate defensin
1.C.85 (TCDB)
PF00323
,
PDBsum
Alpha-defensin 2
Homo sapiens
(
1zmi
, 1zmh, 1zmk)
Alpha-defensin 4
Homo sapiens
(
1zmm
)
Alpha-defensin 5
Homo sapiens
(
1zmp
, 3i5w)
Alpha-defensin 6
Homo sapiens
(
1zmq
)
Alpha-defensin corticostatin-related peptide RK-1
Oryctolagus cuniculus
(
1ews
)
Alpha-defensin cryptdin-4
Mus musculus
(
1tv0
, 2gw9, 2gwp)
Beta-defensin 1
Homo sapiens
(
1ijv
, 1e4s, 1iju, 1kj5, 2nlb, 2nlc, 2nld, 2nle, 2nlf, 2nlg, 2nlh, 2nlp, 2nlq, 2nls, 2plz)
Beta-defensin 12
Bos taurus
(
1bnb
)
Beta-defensin 2
Homo sapiens
(
1fd3
, 1e4q, 1fd4, 1fqq)
Beta-defensin 3
Homo sapiens
(
1kj6
)
Beta-defensin 7
Mus musculus
(
1e4t
)
Beta-defensin 8
Mus musculus
(
1e4r
)
Defensin-like peptide 1
Ornithorhynchus anatinus
(
1b8w
)
Defensin-like peptide 2/4
Ornithorhynchus anatinus
(
1d6b
, 1zue, 1zuf)
Gallinacin-2
Gallus gallus
(
2lg5
, 2lg6)
Neutrophil defensin 1
Homo sapiens
(
2pm1
, 2kht, 3h6c, 3hj2, 3hjd, 3lo1, 3lo2, 3loe, 3lvx)
Neutrophil defensin 1, dimer
Homo sapiens
(
3gny
, 2lo2, 3lo4, 3lo6, 3lo9)
Neutrophil defensin 3
Homo sapiens
(
1dfn
, 1zmh, 1zmi, 1zmk, 2pm4, 2pm5)
Oral alpha defensin 1
Macaca mulatta
(
2k1i
)
Pelovaterin
Pelodiscus sinensis (Chinese softshell turtle)
(
2jr3
)
Reptilian defensin
Caretta caretta
(
2b5b
)
Spheniscin-2 (bird defensin)
Aptenodytes patagonicus
(
1ut3
)
See list of these PDB codes
2.2.41.01. Vertebrate defensin
1.C.85 (TCDB)
PF00323
,
PDBsum
(22 proteins)
Protein Name
PDB ID
Species
Localization
Num. Subunits
Num. TM Sec. Structs.
Hydrophobic Thickness or Depth (Å)
Tilt Angle (°)
ΔG
transfer
(kcal/mol)
Alpha-defensin 2
1zmi
Homo sapiens
Secreted
1
0
2.3 ± 1.1
81 ± 17
-3.7
Alpha-defensin 4
1zmm
Homo sapiens
Secreted
1
0
2.2 ± 1.0
76 ± 10
-5.5
Alpha-defensin 5
1zmp
Homo sapiens
Secreted
1
0
4.2 ± 1.6
84 ± 14
-2.8
Alpha-defensin 6
1zmq
Homo sapiens
Secreted
1
0
3.7 ± 1.6
76 ± 18
-3.6
Alpha-defensin corticostatin-related peptide RK-1
1ews
Oryctolagus cuniculus
Secreted
1
0
4.7 ± 1.1
18 ± 17
-4.4
Alpha-defensin cryptdin-4
1tv0
Mus musculus
Secreted
1
0
2.9 ± 1.4
67 ± 13
-4.5
Beta-defensin 1
1ijv
Homo sapiens
Secreted
1
0
3.5 ± 1.9
74 ± 17
-5.4
Beta-defensin 12
1bnb
Bos taurus
Secreted
1
0
6.0 ± 1.6
88 ± 15
-10.8
Beta-defensin 2
1fd3
Homo sapiens
Secreted
1
0
5.2 ± 1.2
80 ± 12
-9.1
Beta-defensin 3
1kj6
Homo sapiens
Secreted
1
0
2.7 ± 1.3
18 ± 18
-5.1
Beta-defensin 7
1e4t
Mus musculus
Secreted
1
0
3.6 ± 1.4
13 ± 19
-5.2
Beta-defensin 8
1e4r
Mus musculus
Secreted
1
0
2.8 ± 1.1
74 ± 19
-5.5
Defensin-like peptide 1
1b8w
Ornithorhynchus anatinus
Secreted
1
0
1.8 ± 0.6
84 ± 2
-4.4
Defensin-like peptide 2/4
1d6b
Ornithorhynchus anatinus
Secreted
1
0
9.2 ± 0.7
73 ± 2
-11.0
Gallinacin-2
2lg5
Gallus gallus
Secreted
1
0
8.0 ± 1.2
62 ± 6
-8.2
Neutrophil defensin 1
2pm1
Homo sapiens
Secreted
1
0
3.6 ± 1.3
85 ± 6
-3.8
Neutrophil defensin 1, dimer
3gny
Homo sapiens
Secreted
2
0
3.5 ± 0.5
84 ± 6
-5.0
Neutrophil defensin 3
1dfn
Homo sapiens
Secreted
2
0
1.4 ± 1.3
87 ± 15
-3.9
Oral alpha defensin 1
2k1i
Macaca mulatta
Secreted
1
0
0.9 ± 3.2
70 ± 15
-2.2
Pelovaterin
2jr3
Pelodiscus sinensis (Chinese softshell turtle)
Secreted
1
0
3.2 ± 2.3
58 ± 5
-3.5
Reptilian defensin
2b5b
Caretta caretta
Secreted
1
0
1.5 ± 0.4
73 ± 1
-4.1
Spheniscin-2 (bird defensin)
1ut3
Aptenodytes patagonicus
Secreted
1
0
3.6 ± 1.6
44 ± 17
-6.2
Copyright © 2005-2013
Andrei Lomize
,
Mikhail Lomize
and
Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA