PDB ID or protein name
See list of these PDB codes

1.1.57.03. Gamma-secretase 1.A.54 (TCDB) PF01080, PDBsum (7 proteins)

Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
Gamma-secretase complex, structure 1 5a63 Homo sapiens Endoplasm. reticulum 4 17 29.8 ± 0.6 5 ± 0 -129.6
Gamma-secretase complex, structure 2 4uis Homo sapiens Endoplasm. reticulum 4 20 36.8 ± 0.1 11 ± 2 -59.6
Gamma-secretase complex, structure 3 5fn2 Homo sapiens Endoplasm. reticulum 4 18 31.4 ± 0.9 6 ± 0 -145.5
Gamma-secretase complex, structure 4 5fn3 Homo sapiens Endoplasm. reticulum 5 19 30.6 ± 0.9 4 ± 0 -155.5
Gamma-secretase complex, structure 5 5fn4 Homo sapiens Endoplasm. reticulum 5 18 30.4 ± 0.9 7 ± 0 -143.1
Gamma-secretase complex, structure 6 5fn5 Homo sapiens Endoplasm. reticulum 4 17 30.2 ± 1.2 2 ± 1 -134.8
Nicastrin, TM helix 2n7r Homo sapiens Endoplasm. reticulum 1 1 31.4 ± 2.4 6 ± 6 -25.6