PDB ID or protein name
See list of these PDB codes

1.1.01.02. G-protein coupled receptors, family A 9.A.14 (TCDB) PF00001, PDBsum (47 proteins)

Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
Opsin, active, retinal-free state, dimer 3cap Bos taurus Eukaryo. plasma 2 14 30.8 ± 1.1 0 ± 0 -130.1
Rhodopsin, inactive, complex with inverse agonist, 11-cis retinal 1gzm Bos taurus Eukaryo. plasma 1 7 32.2 ± 1.5 11 ± 1 -75.6
Squid rhodopsin, inactive, complex with inverse agonist 11-cis retinal, dimer 2z73 Todarodes pacificus Eukaryo. plasma 2 14 32.9 ± 1.0 0 ± 1 -143.3
Rhodopsin, constitutively active mutant (metarhodopsin II), dimer 2x72 Bos taurus Eukaryo. plasma 2 14 30.0 ± 0.6 0 ± 0 -132.0
Beta-2 adrenergic receptor, active state, complex with G-protein 3sn6 Homo sapiens Eukaryo. plasma 1 7 31.0 ± 1.6 8 ± 1 -68.2
Adenosine receptor A2a, inactive state, engineered, complex with inverse agonist 3pwh Homo sapiens Eukaryo. plasma 1 7 31.0 ± 1.3 9 ± 0 -67.3
Rhodopsin, partially active, photobleached 2i37 Bos taurus Eukaryo. plasma 1 7 31.9 ± 1.5 5 ± 1 -79.1
Rhodopsin, inactive state, a dimer 2i36 Bos taurus Eukaryo. plasma 2 14 30.0 ± 1.4 4 ± 4 -125.6
Melanocortin-4 receptor model (active state) with agonist NDP-MSH 2iqr Homo sapiens Eukaryo. plasma 1 7 33.5 ± 2.0 24 ± 0 -60.6
Melanocortin-4 receptor model (inactive state) with antagonist AGRP 2iqv Homo sapiens Eukaryo. plasma 1 7 31.9 ± 1.1 19 ± 0 -49.1
Opioid mu receptor 4dkl Mus musculus Eukaryo. plasma 2 14 32.0 ± 1.0 5 ± 0 -134.7
Beta-2 adrenergic receptor, inactive state, dimer 2rh1 Homo sapiens Eukaryo. plasma 2 14 31.8 ± 0.9 0 ± 1 -143.2
Adenosine receptor A2a, inactive state, complex with antagonist 3eml Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 8 ± 12 -66.1
TM1-TM2 fragment of fungal STE2 receptor 2k9p Saccharomyces cerevisiae Eukaryo. plasma 1 2 29.8 ± 3.1 21 ± 4 -10.5
Squid rhodopsin, inactive, complex with inverse agonist 11-cis retinal 2ziy Todarodes pacificus Eukaryo. plasma 1 7 32.9 ± 1.7 11 ± 2 -75.1
C-X-C chemokine receptor type 4, inactive, complex with antagonist 3oe6 Homo sapiens Eukaryo. plasma 1 7 35.3 ± 2.5 8 ± 7 -79.7
C-X-C chemokine receptor type 4, inactive, with cyclic peptide antagonist 3oe0 Homo sapiens Eukaryo. plasma 2 14 32.2 ± 2.0 5 ± 6 -133.2
C-X-C chemokine receptor type 4, inactive, dimer, complex with antagonist 3odu Homo sapiens Eukaryo. plasma 2 17 31.2 ± 1.1 0 ± 0 -129.5
Dopamine D3 receptor 3pbl Homo sapiens Eukaryo. plasma 1 7 33.0 ± 1.8 8 ± 1 -56.6
Beta-1 adrenergic receptor, inactive, complex with agonist 2y02 Meleagris gallopavo Eukaryo. plasma 1 7 31.4 ± 1.3 2 ± 0 -76.9
Rhodopsin, inactive, conformation 2 3oax Bos taurus Eukaryo. plasma 1 7 30.9 ± 1.4 11 ± 0 -73.6
Beta-2 adrenergic receptor, active state, complex with antibody 3p0g Homo sapiens Eukaryo. plasma 1 7 30.1 ± 1.4 9 ± 1 -62.9
Rhodopsin, active (metarhodopsin II), complex with peptide of transducin 3pqr Bos taurus Eukaryo. plasma 1 7 31.8 ± 1.1 9 ± 1 -78.3
Rhodopsin, active (metarhodopsin II), without transducin peptide, dimer 3pxo Bos taurus Eukaryo. plasma 2 14 31.8 ± 1.2 0 ± 0 -125.4
Adenosine receptor A2a, partially active state, complex with agonist 3qak Homo sapiens Eukaryo. plasma 1 7 29.8 ± 1.2 9 ± 0 -70.0
Adenosine receptor A2a, partially active state, engineered, complex with agonist 2ydv Homo sapiens Eukaryo. plasma 1 7 31.0 ± 1.3 10 ± 0 -61.4
Beta-1 adrenergic receptor, inactive, complex with antagonist 2ycw Meleagris gallopavo Eukaryo. plasma 1 7 32.2 ± 1.3 2 ± 0 -77.8
Histamine H1 receptor 3rze Homo sapiens Eukaryo. plasma 1 7 32.0 ± 1.4 1 ± 1 -72.4
Beta-2 adrenergic receptor, inactive state 4gbr Homo sapiens Eukaryo. plasma 1 7 31.6 ± 1.3 7 ± 1 -71.7
Beta-1 adrenergic receptor, inactive, multiple mutations 2vt4 Meleagris gallopavo Eukaryo. plasma 1 7 32.8 ± 1.6 3 ± 1 -74.6
Muscarinic acetylcholine receptor M2 3uon Homo sapiens Eukaryo. plasma 1 7 31.8 ± 2.1 4 ± 2 -68.5
Adenosine receptor A2a, complex with antibody 3vga Homo sapiens Eukaryo. plasma 1 7 30.4 ± 1.4 7 ± 2 -62.8
Sphingosine 1-phosphate receptor 1 3v2y Homo sapiens Eukaryo. plasma 1 7 32.2 ± 1.4 10 ± 0 -65.9
Muscarinic acetylcholine receptor M3 4daj Rattus norvegicus Eukaryo. plasma 1 7 32.2 ± 1.2 5 ± 0 -75.8
Opioid kappa receptor 4djh Homo sapiens Eukaryo. plasma 2 14 32.0 ± 0.8 1 ± 0 -146.6
Adenosine receptor A2a, complex with antagonist 3uza Homo sapiens Eukaryo. plasma 1 7 31.6 ± 0.6 8 ± 1 -72.5
Nociceptin receptor 4ea3 Homo sapiens Eukaryo. plasma 1 7 32.0 ± 1.2 7 ± 1 -65.6
Opioid delta receptor 4ej4 Mus musculus Eukaryo. plasma 1 7 34.4 ± 0.8 11 ± 6 -73.2
Adenosine receptor A2a, inactive state, with annular lipids 4eiy Homo sapiens Eukaryo. plasma 1 7 32.2 ± 1.2 18 ± 0 -70.4
Neurotensin receptor type 1 4grv Rattus norvegicus Eukaryo. plasma 1 7 31.6 ± 1.1 4 ± 1 -75.1
C-X-C chemokine receptor type 1 2lnl Homo sapiens Eukaryo. plasma 1 7 30.2 ± 0.9 19 ± 6 -54.4
Thrombin (proteinase-activated) receptor 1, PAR1 3vw7 Homo sapiens Eukaryo. plasma 1 7 33.4 ± 1.9 1 ± 0 -72.2
Beta-1 adrenergic receptor, inactive, dimer 4gpo Meleagris gallopavo Eukaryo. plasma 2 14 30.8 ± 1.2 0 ± 0 -144.8
5-hydroxytryptamine receptor 2B 4ib4 Homo sapiens Eukaryo. plasma 1 7 34.0 ± 2.3 16 ± 2 -69.2
5-hydroxytryptamine receptor 1B, conformation 1 4iar Homo sapiens Eukaryo. plasma 1 7 33.6 ± 1.8 7 ± 1 -76.4
5-hydroxytryptamine receptor 1B, conformation 2 4iaq Homo sapiens Eukaryo. plasma 1 7 34.4 ± 1.7 6 ± 1 -77.4
Rhodopsin, inactive, conformation 3 1u19 Bos taurus Eukaryo. plasma 1 7 31.2 ± 1.5 12 ± 1 -71.9