Family » 1.1.09.01. P-ATPase <a href="http://www.tcdb.org/tcdb/index.php?tc=3.A.3" class="external" target="_blank">3.A.3 (TCDB)</a> <a href="http://pfam.sanger.ac.uk/family/PF00122" class="external" target="_blank">PF00122</a>, <a href="http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPfamStr.pl?pfam_id=PF00122" class="external" target="_blank">PDBsum</a> - Orientations of Proteins in Membranes (OPM) database

Type:1. Transmembrane (3 classes)
Class:1.1. Alpha-helical polytopic (72 superfamilies)
Superfamily:1.1.09. P-type ATPase (P-ATPase) (1 family) 3.A.3 (TCDB)
Family:
1.1.09.01. P-ATPase 3.A.3 (TCDB) PF00122, PDBsum

Calcium ATPase, E1 Ca2+ state, complex with sarcolipin

Oryctolagus cuniculus (4h1w)

Calcium ATPase, E1 Mg2+ state, complex with sarcolipin

Oryctolagus cuniculus (3w5a, 3w5b)

Calcium ATPase, E1-2Ca state, conformation 1

Oryctolagus cuniculus (3ar2, 1vfp)

Calcium ATPase, E1-2Ca state, conformation 2

Oryctolagus cuniculus (3ba6, 1t5t)

Calcium ATPase, E1-2Ca state, conformation 3

Oryctolagus cuniculus (1su4)

Calcium ATPase, E1-2Ca state, conformation 4

Oryctolagus cuniculus (2c9m)

Calcium ATPase, E1-ATP state

Oryctolagus cuniculus (1t5s, 3n8g)

Calcium ATPase, E1P-ADP state

Oryctolagus cuniculus (2zbd)

Calcium ATPase, E2 state (Ca-free), conformation 1

Oryctolagus cuniculus (2agv, 1iwo, 2dqs, 3ar3, 3ar4, 3ar5, 3ar6, 3ar7, 3w5c, 3w5d)

Calcium ATPase, E2 state (Ca-free), conformation 2

Oryctolagus cuniculus (2by4, 2c88, 2c8k, 2c8l, 2yfy, 3nal, 3nam, 3nan)

Calcium ATPase, E2 state (Ca-free), conformation 4

Oryctolagus cuniculus (3fps, 2oa0)

Calcium ATPase, E2 state (Ca-free), conformation 5

Oryctolagus cuniculus (1kju)

Calcium ATPase, E2 state (Ca-free), conformation 6

Oryctolagus cuniculus (2zbe)

Calcium ATPase, E2 state (Ca-free), conformation 8

Oryctolagus cuniculus (2zbg)

Calcium ATPase, E2 state, Ca-free, conformation 3

Oryctolagus cuniculus (2ear, 2eas, 2eat, 2eau)

Calcium ATPase, E2 state, Ca-free, conformation 7

Oryctolagus cuniculus (3ar9, 2zbf)

Calcium ATPase, E2-Pi state, conformation 1

Oryctolagus cuniculus (1wpg)

Calcium ATPase, E2-Pi state, conformation 2

Oryctolagus cuniculus (3ar8)

Calcium ATPase, E2-Pi state, conformation 3

Oryctolagus cuniculus (3b9b)

Calcium ATPase, E2-Pi state, conformation 4

Oryctolagus cuniculus (3b9r)

Calcium ATPase, E2-Pi state, conformation 5

Oryctolagus cuniculus (3fpb, 2o9j, 3fgo)

Calcium ATPase, E2-Pi state, conformation 6

Oryctolagus cuniculus (1xp5)

Calcium ATPase, E2-Pi state, conformation 7

Oryctolagus cuniculus (3n5k)

Copper efflux ATPase

Legionella pneumophila (3rfu)

Copper efflux ATPase, CopA

Archaeoglobus fulgidus (3j08, 3j09)

Copper efflux ATPase, CopA, alternative conformation

Archaeoglobus fulgidus (3j09, 3j08)

Plasma membrane ATPase

Neurospora crassa (1mhs)

Plasma membrane ATPase 2, E1-ATP state

Arabidopsis thaliana (3b8c)

Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

Bos taurus (3tlm)

Sodium-potassium pump, E2-Pi state

Sus scrofa (3b8e)

Sodium-potassium pump, different conformation

Sus scrofa (3n23, 3n2f)

Sodium-potassium pump, E2-Pi state

Squalus acanthias (2zxe, 3a3y)

Sodium-potassium pump, E2-Pi state, slightly different conf.

Sus scrofa (3kdp)

Sodium-potassium pump, gastric

Sus scrofa (2xzb, 3ixz)

Sodium-potassium pump, gastric, different conformation

Sus scrofa (2yn9)

1.1.09.01. P-ATPase 3.A.3 (TCDB) PF00122, PDBsum (35 proteins)

Protein Name	PDB ID	Species	Localization	Num. Subunits	Num. TM Sec. Structs.	Hydrophobic Thickness or Depth (Å)	Tilt Angle (°)	ΔG_transfer (kcal/mol)
Sodium-potassium pump, different conformation	3n23	Sus scrofa	Eukaryo. plasma	3	12	29.9 ± 0.9	6 ± 0	-96.0
Sodium-potassium pump, E2-Pi state	3b8e	Sus scrofa	Eukaryo. plasma	3	12	30.7 ± 0.9	12 ± 0	-93.6
Sodium-potassium pump, E2-Pi state	2zxe	Squalus acanthias	Eukaryo. plasma	3	12	31.9 ± 1.8	9 ± 0	-96.3
Sodium-potassium pump, E2-Pi state, slightly different conf.	3kdp	Sus scrofa	Eukaryo. plasma	3	12	31.4 ± 1.4	7 ± 0	-95.3
Copper efflux ATPase, CopA	3j08	Archaeoglobus fulgidus	Archaebac.	2	16	27.6 ± 0.8	0 ± 0	-72.3
Copper efflux ATPase, CopA, alternative conformation	3j09	Archaeoglobus fulgidus	Archaebac.	2	16	27.0 ± 0.1	1 ± 0	-23.5
Plasma membrane ATPase	1mhs	Neurospora crassa	Eukaryo. plasma	2	20	29.5 ± 0.2	7 ± 0	-109.6
Sodium-potassium pump, gastric, different conformation	2yn9	Sus scrofa	Eukaryo. plasma	2	11	30.6 ± 0.8	10 ± 0	-85.9
Calcium ATPase, E1 Mg2+ state, complex with sarcolipin	3w5a	Oryctolagus cuniculus	Endoplasm. reticulum	2	11	26.8 ± 0.7	30 ± 0	-67.4
Calcium ATPase, E1 Ca2+ state, complex with sarcolipin	4h1w	Oryctolagus cuniculus	Endoplasm. reticulum	2	11	27.6 ± 1.0	27 ± 1	-67.6
Sodium-potassium pump, gastric	2xzb	Sus scrofa	Eukaryo. plasma	2	11	29.7 ± 1.2	9 ± 0	-91.4
Calcium ATPase, E1-2Ca state, conformation 2	3ba6	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.8 ± 0.7	19 ± 0	-59.4
Calcium ATPase, E2-Pi state, conformation 2	3ar8	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	28.6 ± 1.8	19 ± 0	-60.6
Calcium ATPase, E2 state (Ca-free), conformation 4	3fps	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.0 ± 0.9	16 ± 0	-53.5
Calcium ATPase, E1-2Ca state, conformation 3	1su4	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.0 ± 2.7	26 ± 1	-68.6
Calcium ATPase, E2-Pi state, conformation 3	3b9b	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.9 ± 1.6	16 ± 2	-58.1
Calcium ATPase, E2 state (Ca-free), conformation 5	1kju	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	33.8 ± 0.2	26 ± 1	-68.6
Calcium ATPase, E1-2Ca state, conformation 4	2c9m	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.8 ± 1.2	27 ± 1	-54.3
Copper efflux ATPase	3rfu	Legionella pneumophila	Bact. Gram-neg inner	1	8	30.0 ± 0.4	16 ± 1	-72.1
Calcium ATPase, E2 state, Ca-free, conformation 7	3ar9	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.0 ± 0.9	20 ± 0	-73.8
Calcium ATPase, E2 state (Ca-free), conformation 6	2zbe	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	28.0 ± 0.7	16 ± 0	-55.4
Calcium ATPase, E1-2Ca state, conformation 1	3ar2	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.6 ± 0.9	25 ± 0	-70.9
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3tlm	Bos taurus	Endoplasm. reticulum	1	10	26.8 ± 0.0	22 ± 0	-57.4
Calcium ATPase, E2 state (Ca-free), conformation 8	2zbg	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.0 ± 1.7	21 ± 0	-66.5
Plasma membrane ATPase 2, E1-ATP state	3b8c	Arabidopsis thaliana	Eukaryo. plasma	1	10	29.5 ± 1.5	9 ± 0	-56.8
Calcium ATPase, E2-Pi state, conformation 1	1wpg	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.6 ± 1.1	20 ± 0	-70.4
Calcium ATPase, E2-Pi state, conformation 4	3b9r	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	26.8 ± 0.0	25 ± 0	-44.1
Calcium ATPase, E2-Pi state, conformation 5	3fpb	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	27.0 ± 2.3	23 ± 0	-64.9
Calcium ATPase, E1-ATP state	1t5s	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.7 ± 1.6	22 ± 1	-58.6
Calcium ATPase, E2-Pi state, conformation 6	1xp5	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	27.4 ± 1.1	25 ± 0	-58.5
Calcium ATPase, E1P-ADP state	2zbd	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	31.8 ± 1.4	22 ± 2	-70.6
Calcium ATPase, E2 state (Ca-free), conformation 2	2by4	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.8 ± 1.3	24 ± 1	-63.7
Calcium ATPase, E2-Pi state, conformation 7	3n5k	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	28.4 ± 1.3	22 ± 2	-64.8
Calcium ATPase, E2 state (Ca-free), conformation 1	2agv	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	29.7 ± 2.2	20 ± 2	-61.5
Calcium ATPase, E2 state, Ca-free, conformation 3	2ear	Oryctolagus cuniculus	Endoplasm. reticulum	1	10	30.0 ± 1.2	19 ± 1	-58.4