PDB ID or protein name
See list of these PDB codes

1.2.32. Cytochrome P450 (1 family) PF00067, PDBsum (49 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
1.2.32.01. Fatty-acid peroxygenase 1izo Bacillus subtilis Bact. Gram-pos plas. 1 0 1.2 ± 0.3 76 ± 1 -5.5
1.2.32.01. Cholesterol 7-alpha-monooxygenase (P450 7A1) 3dax Homo sapiens Endoplasm. reticulum 1 0 1.8 ± 1.9 69 ± 8 -3.9
1.2.32.01. Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 1 2q9f Homo sapiens Endoplasm. reticulum 1 0 2.8 ± 1.0 86 ± 7 -5.8
1.2.32.01. Cholesterol side-chain cleavage enzyme (P450 11A1) 3mzs Bos taurus Mitochon. inner 1 0 3.2 ± 0.3 33 ± 1 -6.7
1.2.32.01. Cytochrome P450 2B4, open state 2 1po5 Oryctolagus cuniculus Endoplasm. reticulum 1 0 3.5 ± 1.4 79 ± 9 -7.2
1.2.32.01. Cytochrome P450 1B1 3pm0 Homo sapiens Endoplasm. reticulum 1 0 3.8 ± 0.7 79 ± 1 -7.0
1.2.32.01. Cytochrome P450 46A1 (cholesterol 24-hydrolase), conformation 2 3mdm Homo sapiens Endoplasm. reticulum 1 0 3.8 ± 1.3 51 ± 8 -5.9
1.2.32.01. Cytochrome P450 2C8 1pq2 Homo sapiens Endoplasm. reticulum 1 0 3.8 ± 1.8 65 ± 9 -8.6
1.2.32.01. Cytochrome P450 2C9, different conformation 1r9o Homo sapiens Endoplasm. reticulum 1 0 4.0 ± 1.1 59 ± 8 -10.1
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 1 2wuz Trypanosoma cruzi Endoplasm. reticulum 1 0 4.0 ± 1.1 75 ± 11 -9.9
1.2.32.01. Cholesterol side-chain cleavage enzyme (P450 11A1), complex with adrenodoxin 3n9y Homo sapiens Mitochon. inner 1 0 4.1 ± 0.6 49 ± 5 -6.2
1.2.32.01. Steroid 17-alpha-hydroxylase/17,20 lyase (P450 17A1) 3swz Homo sapiens Endoplasm. reticulum 1 0 4.2 ± 1.6 56 ± 3 -8.4
1.2.32.01. Cytochrome P450 2B4, closed state 1 1suo Oryctolagus cuniculus Endoplasm. reticulum 1 0 4.6 ± 1.3 57 ± 4 -14.2
1.2.32.01. Cytochrome P450 2B6 3ibd Homo sapiens Endoplasm. reticulum 1 0 4.7 ± 1.0 57 ± 3 -10.8
1.2.32.01. Cytochrome P450 2B6, different conformation 3ua5 Homo sapiens Endoplasm. reticulum 1 0 4.7 ± 1.1 55 ± 3 -12.9
1.2.32.01. Cytochrome P450 11B2, mitochondrial 4dvq Homo sapiens Mitochon. inner 1 0 4.8 ± 0.6 48 ± 4 -9.1
1.2.32.01. Cytochrome P450 2A13 2p85 Homo sapiens Endoplasm. reticulum 1 0 4.9 ± 0.4 47 ± 2 -10.0
1.2.32.01. Cytochrome P450 2A6 1z10 Homo sapiens Endoplasm. reticulum 1 0 5.0 ± 1.7 44 ± 18 -9.5
1.2.32.01. Prostacyclin synthase (cytochrome P450 8A1) 3b6h Homo sapiens Endoplasm. reticulum 1 0 5.0 ± 1.6 64 ± 18 -6.3
1.2.32.01. Cytochrome P450 1n97 Thermus thermophilus Bact. Gram-neg inner 1 0 5.2 ± 0.3 43 ± 5 -9.9
1.2.32.01. Cytochrome P450 120a1, different conformation 2ve3 Synechocystis sp. Thylakoid 1 0 5.2 ± 1.5 52 ± 15 -6.8
1.2.32.01. Cytochrome P450 2B4, closed state 2 2q6n Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.5 ± 0.4 55 ± 2 -13.0
1.2.32.01. Cytochrome P450 2B4, open state 3 3r1b Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.7 ± 0.0 43 ± 5 -9.8
1.2.32.01. Cytochrome P450 2B4, closed state 3 3g5n Oryctolagus cuniculus Endoplasm. reticulum 1 0 5.7 ± 1.8 65 ± 3 -12.1
1.2.32.01. Plant cytochrome P450 74A (allene oxide synthase) 3dsk Arabidopsis thaliana Thylakoid 1 0 5.7 ± 0.5 67 ± 3 -20.0
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 2 2wx2 Trypanosoma cruzi Endoplasm. reticulum 1 0 5.9 ± 5.9 63 ± 2 -6.2
1.2.32.01. Steroid 21-hydroxylase (P450 C21) 3qz1 Bos taurus Endoplasm. reticulum 1 0 5.9 ± 1.6 72 ± 3 -10.4
1.2.32.01. Cholesterol 7-alpha-monooxygenase (P450 7A1), different conformation 3sn5 Homo sapiens Endoplasm. reticulum 1 0 6.0 ± 1.9 73 ± 4 -6.5
1.2.32.01. Cytochrome P450 19A1 (aromatase, estrogen synthetase) 3eqm Homo sapiens Endoplasm. reticulum 1 0 6.1 ± 1.2 58 ± 8 -12.4
1.2.32.01. Cytochrome P450 120a1 2ve4 Synechocystis sp. Thylakoid 1 0 6.3 ± 0.9 47 ± 8 -8.6
1.2.32.01. Cytochrome P450 24a1 (1,25-dihydroxyvitamin D(3) 24-hydroxylase) 3k9v Rattus norvegicus Mitochon. inner 1 0 6.6 ± 1.0 49 ± 6 -9.6
1.2.32.01. Cytochrome P450 1A2 2hi4 Homo sapiens Endoplasm. reticulum 1 0 6.9 ± 1.0 66 ± 9 -16.2
1.2.32.01. Cytochrome P450 2D6, conformation 1 2f9q Homo sapiens Endoplasm. reticulum 1 0 7.0 ± 1.8 29 ± 10 -12.0
1.2.32.01. Cytochrome P450 1A1 4i8v Homo sapiens Endoplasm. reticulum 1 0 7.1 ± 1.0 64 ± 3 -15.1
1.2.32.01. Cytochrome P450 2C5, different conformation 1dt6 Oryctolagus cuniculus Endoplasm. reticulum 1 0 7.3 ± 1.0 13 ± 7 -8.8
1.2.32.01. Plant cytochrome P450 74A (allene oxide synthase) 3dan Parthenium argentatum Vacuole 1 0 7.5 ± 0.4 64 ± 2 -24.1
1.2.32.01. Cytochrome P450 2C9 1og5 Homo sapiens Endoplasm. reticulum 1 0 7.6 ± 1.0 79 ± 6 -13.7
1.2.32.01. Sterol 14-alpha-demethylase (CYP51), conformation 3 3ksw Trypanosoma cruzi Endoplasm. reticulum 1 0 8.0 ± 6.7 61 ± 6 -9.1
1.2.32.01. Cytochrome P450 2D6, conformation 2 3tda Homo sapiens Endoplasm. reticulum 1 0 8.0 ± 0.7 35 ± 7 -12.5
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3g1q Trypanosoma brucei Endoplasm. reticulum 1 0 8.1 ± 1.5 62 ± 12 -10.8
1.2.32.01. Cytochrome P450 2E1 3e6i Homo sapiens Endoplasm. reticulum 1 0 8.3 ± 2.0 49 ± 8 -14.2
1.2.32.01. Cytochrome P450 2R1 3czh Homo sapiens Endoplasm. reticulum 1 0 8.3 ± 1.5 48 ± 13 -13.2
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3l4d Leishmania infantum Endoplasm. reticulum 1 0 8.4 ± 1.8 66 ± 9 -12.6
1.2.32.01. Cytochrome P450 3A4, conformation 1 1tqn Homo sapiens Endoplasm. reticulum 1 0 8.7 ± 1.0 67 ± 11 -18.5
1.2.32.01. Sterol 14-alpha-demethylase (CYP51) 3ld6 Homo sapiens Endoplasm. reticulum 1 0 8.9 ± 0.6 57 ± 2 -16.8
1.2.32.01. Cytochrome P450 2D6, conformation 3 3qm4 Homo sapiens Endoplasm. reticulum 1 0 9.0 ± 1.4 35 ± 11 -9.3
1.2.32.01. Cytochrome P450 3A4, conformation 2 3nxu Homo sapiens Endoplasm. reticulum 1 0 9.3 ± 1.0 52 ± 12 -17.5
1.2.32.01. Cytochrome P450 2C5 1nr6 Oryctolagus cuniculus Endoplasm. reticulum 1 0 10.6 ± 1.0 54 ± 18 -9.1
1.2.32.01. Cytochrome P450 2B4, open state 1 2bdm Oryctolagus cuniculus Endoplasm. reticulum 1 0 10.6 ± 1.0 48 ± 15 -16.2