PDB ID or protein name
See list of these PDB codes

2.3.06. Alpha/beta-hydrolases (15 families) CL0028, PDBsum (97 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.3.06.01. Bile-salt activated lipase, structure 2 1jmy Homo sapiens Secreted 1 0 5.0 ± 1.4 85 ± 9 -5.3
2.3.06.01. Acetylcholinesterase 1ea5 Torpedo californica Eukaryo. plasma 1 0 1.8 ± 1.1 34 ± 5 -4.7
2.3.06.01. Acetylcholinesterase 1n5m Mus musculus Eukaryo. plasma 1 0 3.7 ± 1.3 28 ± 6 -6.1
2.3.06.01. Acetylcholinesterase, complex with fasciculin-2 4bdt Homo sapiens Eukaryo. plasma 2 0 10.7 ± 0.8 56 ± 3 -11.6
2.3.06.01. Butyryl cholinesterase 1p0i Homo sapiens Eukaryo. plasma 1 0 3.1 ± 0.8 43 ± 10 -6.4
2.3.06.01. Bile-salt activated lipase, conformation 1 1aql Bos taurus Secreted 1 0 5.7 ± 1.1 78 ± 7 -9.6
2.3.06.01. Bile-salt activated lipase, structure 1 1f6w Homo sapiens Secreted 1 0 1.8 ± 0.5 81 ± 10 -5.1
2.3.06.01. Bile-salt activated lipase, conformation 3 2bce Bos taurus Secreted 1 0 5.3 ± 0.8 74 ± 6 -7.0
2.3.06.01. Bile-salt activated lipase, conformation 2 1akn Bos taurus Secreted 1 0 3.8 ± 1.5 77 ± 15 -6.7
2.3.06.01. Acetylcholinesterase 1qon Drosophila melanogaster Eukaryo. plasma 1 0 5.5 ± 1.6 4 ± 13 -5.0
2.3.06.01. Neuroligin-1, complex with neurexin-1-beta 3biw Rattus norvegicus Eukaryo. plasma 2 0 5.9 ± 1.0 80 ± 3 -8.8
2.3.06.01. Neuroligin-2 3bl8 Mus musculus Eukaryo. plasma 1 0 1.7 ± 1.6 32 ± 5 -4.1
2.3.06.01. Neuroligin-1, complex with human neurexin-1-alpha 3b3q Mus musculus Eukaryo. plasma 2 0 1.8 ± 1.0 81 ± 1 -3.6
2.3.06.01. Neuroligin-4, X-linked, complex with neurexin 1-beta 2xb6 Homo sapiens Eukaryo. plasma 2 0 1.9 ± 3.0 84 ± 11 -3.3
2.3.06.01. Acetylcholinesterase 4ey4 Homo sapiens Eukaryo. plasma 1 0 3.2 ± 0.5 33 ± 2 -8.4
2.3.06.02. Antigen 85b 1f0n Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 3.7 ± 0.9 33 ± 7 -7.4
2.3.06.02. Antigen 85c 1va5 Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 4.2 ± 0.2 34 ± 3 -8.2
2.3.06.02. Antigen 85a 1sfr Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 2.8 ± 0.8 27 ± 9 -7.5
2.3.06.02. MPT51/MPB51 antigen 1r88 Mycobacterium tuberculosis Bact. Gram-pos cell wall 1 0 1.8 ± 1.0 28 ± 26 -3.9
2.3.06.03. Gastric lipase, closed state 1hlg Homo sapiens Secreted 1 0 3.2 ± 1.4 6 ± 12 -5.6
2.3.06.03. Gastric lipase, open (active) state 1k8q Canis lupus familiaris Secreted 1 0 7.2 ± 0.5 78 ± 6 -12.6
2.3.06.04. Palmitoyl protein thioesterase 1 1eh5 Bos taurus Lysosome 1 0 5.3 ± 0.9 59 ± 6 -8.1
2.3.06.04. Palmitoyl protein thioesterase 2 1pja Homo sapiens Lysosome 1 0 3.7 ± 1.6 60 ± 15 -4.6
2.3.06.04. Palmitoyl-protein thioesterase 1 3gro Homo sapiens Lysosome 1 0 3.6 ± 0.1 55 ± 3 -6.8
2.3.06.04. Acyl transferase LuxD 1tht Vibrio harveyi Bact. Gram-neg inner 1 0 3.3 ± 1.3 85 ± 4 -6.1
2.3.06.05. Copper inducible hydrolase YahD 3og9 Lactococcus lactis Bact. Gram-pos plas. 1 0 1.4 ± 1.1 33 ± 10 -4.0
2.3.06.05. Carboxylesterase 2h1i Bacillus cereus Bact. Gram-pos plas. 1 0 2.3 ± 1.8 32 ± 31 -3.6
2.3.06.05. Carboxylesterase 2 1auo Pseudomonas fluorescens Bact. Gram-neg inner 1 0 1.7 ± 3.0 33 ± 21 -3.4
2.3.06.05. Acyl-protein thioesterase 1 1fj2 Homo sapiens Eukaryo. plasma 1 0 9.6 ± 2.0 64 ± 14 -4.7
2.3.06.05. Carboxylesterase 3cn9 Pseudomonas aeruginosa Bact. Gram-neg inner 1 0 3.5 ± 2.1 11 ± 32 -4.1
2.3.06.05. Thermostable Esterase 3doh Thermotoga maritima Bact. Gram-neg inner 1 0 4.0 ± 2.0 84 ± 13 -4.4
2.3.06.06. Lipase B, open state 1lbs Candida antarctica Secreted 1 0 3.7 ± 1.0 76 ± 6 -12.7
2.3.06.06. Triacylglycerol lipase, closed (inactive) state 3tgl Rhizomucor miehei Secreted 1 0 2.7 ± 1.1 39 ± 7 -5.8
2.3.06.06. Triacylglycerol lipase, open (active) state 4tgl Rhizomucor miehei Secreted 1 0 8.8 ± 0.9 64 ± 11 -18.2
2.3.06.06. Triacylglycerol lipase, open (active) state 1ein Humicola lanuginosa Secreted 1 0 8.1 ± 0.8 63 ± 4 -14.5
2.3.06.06. Triacylglycerol lipase 1lgy Rhizopus niveus Secreted 1 0 1.9 ± 1.8 33 ± 16 -4.8
2.3.06.06. Lipase 1, open (active) state 1lpp Candida rugosa Secreted 1 0 10.0 ± 0.4 83 ± 1 -28.0
2.3.06.06. Lipase 2 1gz7 Candida rugosa Secreted 1 0 4.8 ± 1.3 87 ± 10 -8.5
2.3.06.06. Type-B carboxylesterase/lipase 1cle Candida cylindracea Secreted 1 0 10.2 ± 0.0 83 ± 0 -24.7
2.3.06.06. Triacylglycerol lipase, closed (inactive) state 1dt5 Humicola lanuginosa Secreted 1 0 5.1 ± 0.9 79 ± 13 -5.9
2.3.06.06. Lipase 1, closed (inactive) state 1trh Candida rugosa Secreted 1 0 4.9 ± 1.3 85 ± 7 -7.4
2.3.06.06. Lipase 2 1thg Geotrichum candidum Secreted 1 0 6.4 ± 1.7 23 ± 14 -4.7
2.3.06.06. Lipase B, circular permutation 3icv Candida antarctica Secreted 2 0 8.3 ± 0.8 83 ± 7 -11.3
2.3.06.06. Lipase LipA 2qua Serratia marcescens Secreted 1 0 8.9 ± 0.2 59 ± 0 -37.5
2.3.06.06. Lipase 2ory Photbacterium lipolyticum Secreted 1 0 6.3 ± 1.1 62 ± 10 -12.0
2.3.06.06. Triacylglycerol lipase 3g7n Penicillium expansum Secreted 1 0 3.8 ± 1.1 81 ± 14 -9.0
2.3.06.06. Lipase 2 3o0d Yarrowia lipolytica Secreted 1 0 6.8 ± 2.4 79 ± 26 -9.4
2.3.06.07. Lipase, complex with foldase 2es4 Pseudomonas glumae Secreted 2 0 8.5 ± 0.0 65 ± 2 -7.2
2.3.06.07. Lipase A 1isp Bacillus subtilis Secreted 1 0 1.9 ± 0.8 59 ± 12 -5.2
2.3.06.07. Lipase 1qge Pseudomonas glumae Secreted 1 0 3.7 ± 0.9 24 ± 3 -7.7
2.3.06.07. Lipase 5lip Burkholderia cepacia Secreted 1 0 9.0 ± 1.0 46 ± 2 -30.6
2.3.06.07. Lipase, open (active) state 1ex9 Pseudomonas aeruginosa Secreted 1 0 11.0 ± 1.0 52 ± 5 -30.0
2.3.06.07. Lipase 1cvl Chromobacterium viscosum Secreted 1 0 9.9 ± 1.0 53 ± 9 -8.7
2.3.06.07. Lipase L1 1ku0 Bacillus stearothermophilus Secreted 1 0 4.0 ± 0.6 23 ± 9 -8.9
2.3.06.07. Lipase L1, different isoform 1ji3 Bacillus stearothermophilus Secreted 1 0 3.5 ± 1.7 22 ± 10 -8.0
2.3.06.07. Thermostable lipase 2dsn Geobacillus zalihae Secreted 1 0 4.9 ± 0.9 32 ± 3 -7.7
2.3.06.07. Lipase 2z8x Pseudomonas sp. MIS 38 Secreted 1 0 6.8 ± 1.7 74 ± 6 -8.2
2.3.06.07. Triacylglycerol lipase 2w22 Geobacillus thermocatenulatus Secreted 1 0 5.6 ± 0.0 86 ± 0 -22.4
2.3.06.07. PHB depolymerase PhaZ7 2x5x Pseudomonas lemoignei Secreted 1 0 4.1 ± 3.0 54 ± 41 -5.6
2.3.06.07. Tentative lipase 2zyr Archaeoglobus fulgidus Secreted 1 0 3.0 ± 1.0 57 ± 8 -7.5
2.3.06.07. Organic solvent tolerant lipase 42 4fkb Bacillus sp. Secreted 1 0 5.0 ± 0.7 26 ± 3 -6.9
2.3.06.07. Lipase 3auk Geobacillus sp. Secreted 1 0 5.6 ± 0.8 25 ± 2 -8.5
2.3.06.07. Thermostable lipase 4fdm Bacillus sp. Secreted 1 0 5.2 ± 0.6 28 ± 2 -8.5
2.3.06.07. Lipase 46 kDa form 2hih Staphylococcus hyicus Secreted 1 0 4.6 ± 0.3 83 ± 1 -16.0
2.3.06.08. Pancreatic lipase 1hpl Equus caballus Secreted 1 0 3.8 ± 0.3 80 ± 5 -8.1
2.3.06.08. Pancreatic lipase, complex with colipase from Pig 1lpb Homo sapiens Secreted 2 0 9.2 ± 0.4 89 ± 2 -24.2
2.3.06.08. Pancreatic lipase, complex with colipase 1eth Sus scrofa Secreted 2 0 13.6 ± 0.2 90 ± 3 -13.3
2.3.06.08. Pancreatic lipase 1gpl Cavia porcellus Secreted 1 0 5.8 ± 1.0 86 ± 9 -7.8
2.3.06.08. Pancreatic lipase 1bu8 Rattus norvegicus Secreted 1 0 3.5 ± 1.3 87 ± 10 -6.1
2.3.06.08. Pancreatic lipase, complex with colipase from Pig 1n8s Homo sapiens Secreted 2 0 7.6 ± 0.6 45 ± 4 -10.8
2.3.06.08. Pancreatic lipase, complex with colipase from Pig 1lpa Homo sapiens Secreted 2 0 11.3 ± 0.1 82 ± 1 -24.5
2.3.06.08. Pancreatic lipase-related protein 2 1w52 Equus caballus Secreted 1 0 4.8 ± 0.2 83 ± 0 -12.7
2.3.06.08. Pancreatic lipase-related protein 1 2ppl Homo sapiens Secreted 1 0 7.1 ± 0.9 79 ± 6 -10.2
2.3.06.08. Pancreatic lipase-related protein 2 2oxe Homo sapiens Secreted 1 0 10.2 ± 1.1 88 ± 8 -10.1
2.3.06.08. Pancreatic lipase-related protein 1 1rp1 Canis lupus familiaris Secreted 1 0 6.3 ± 1.0 79 ± 4 -7.5
2.3.06.09. Cutinase 1 1oxm Fusarium solani Secreted 1 0 6.8 ± 1.1 36 ± 15 -9.1
2.3.06.09. Lysin B from mycobacteriophage 3hc7 Mycobacterium phage D29 Bact. Gram-pos plas. 1 0 6.6 ± 2.0 50 ± 12 -7.0
2.3.06.09. Mycobacterial lipase 3aja Mycobacterium smegmatis Secreted 1 0 6.0 ± 1.0 28 ± 10 -6.7
2.3.06.09. Cutinase 1 3gbs Aspergillus oryzae Secreted 1 0 11.2 ± 0.5 55 ± 5 -12.6
2.3.06.09. Cutinase 1 3dcn Colletotrichum gloeosporioides Secreted 1 0 5.7 ± 1.2 44 ± 8 -10.1
2.3.06.09. Cutinase-like protein 2czq Cryptococcus sp. Secreted 1 0 4.9 ± 1.3 54 ± 16 -9.0
2.3.06.10. Lipase 1jfr Streptomyces exfoliatus Secreted 1 0 5.0 ± 1.3 60 ± 10 -6.4
2.3.06.10. Lipase 2fx5 Pseudomonas mendocina Secreted 1 0 5.5 ± 1.0 50 ± 5 -8.4
2.3.06.10. FTsh 3d59 Dendroaspis polylepis polylepis (Black mamba) Endosome 1 0 5.5 ± 1.2 87 ± 10 -13.6
2.3.06.11. Monoglyceride lipase MGLL, open ligand-free conformation 3jw8 Homo sapiens Eukaryo. plasma 1 0 8.1 ± 1.3 11 ± 9 -11.3
2.3.06.11. Monoglyceride lipase MGLL, closed ligand-bound conformation 3pe6 Homo sapiens Eukaryo. plasma 1 0 0.9 ± 3.0 54 ± 28 -2.7
2.3.06.12. Carboxylesterase (EstA) 1jji Archaeoglobus fulgidus Archaebac. 1 0 2.8 ± 1.0 56 ± 22 -4.8
2.3.06.12. Heroin esterase 1lzk Rhodococcus sp. Bact. Gram-pos plas. 1 0 1.5 ± 1.5 69 ± 9 -4.0
2.3.06.12. Gibberellin receptor GID1 3ebl Oryza sativa (Rice) Nuclear inner 1 0 5.2 ± 1.5 59 ± 14 -9.1
2.3.06.12. Carboxylesterase 2hm7 Alicyclobacillus acidocaldarius Bact. Gram-pos plas. 1 0 5.8 ± 1.7 70 ± 5 -7.7
2.3.06.12. Gibberellin receptor GID1A 2zsh Arabidopsis thaliana Nuclear inner 1 0 2.6 ± 1.2 89 ± 6 -5.0
2.3.06.12. Esterase LipW 3qh4 Mycobacterium marinum Bact. Gram-pos plas. 1 0 2.4 ± 1.2 76 ± 32 -5.0
2.3.06.13. Protein NDRG2 2qmq Mus musculus Eukaryo. plasma 1 0 8.3 ± 2.2 43 ± 14 -9.6
2.3.06.13. Protein Ndr1 2xmr Homo sapiens Eukaryo. plasma 1 0 8.2 ± 2.6 50 ± 10 -8.8
2.3.06.14. Esterase LipA 3h2g Xanthomonas oryzae Secreted 1 0 5.1 ± 1.7 87 ± 8 -4.9
2.3.06.14. Lipase A, closed state 3guu Candida antarctica Secreted 1 0 4.4 ± 1.0 80 ± 2 -10.9
2.3.06.15. Polyneuridine-aldehyde esterase 2wfm Rauvolfia serpentina (Serpentwood) Endoplasm. reticulum 1 0 2.5 ± 1.7 88 ± 3 -4.6