- Type:1. Transmembrane (2 classes)
- Class:1.1. Alpha-helical transmembrane (54 superfamilies)
- Superfamily:1.1.26. Pentameric ligand-gated ion channels (2 families) 1.A.9 (TCDB)
- Family:
- 1.1.26.01.Ligand-gated ion channel of neurotransmitter receptors 1.A.9 (TCDB)
Acetylcholine receptor
- 1.1.26.02.Prokaryotic pentameric ligand-gated ion channels 1.A.9 (TCDB)
Ligand gated ion channel, active conformation
Ligand gated ion channel, inactive conformation
1.1.26. Pentameric ligand-gated ion channels (2 families) 1.A.9 (TCDB) (3 proteins)
| Family | Protein Name | PDB ID | Species | Localization | Num. Subunits | Num. TM Sec. Structs. | Hydrophobic Thickness or Depth (Å) | Tilt Angle (°) | ΔGtransfer (kcal/mol) |
|---|---|---|---|---|---|---|---|---|---|
| 1.1.26.01. | Acetylcholine receptor | 2bg9 | Torpedo marmorata | Eukaryo. plasma | 5 | 20 | 31.0 ± 1.6 | 3 ± 2 | -158.0 |
| 1.1.26.02. | Ligand gated ion channel, inactive conformation | 2vl0 | Erwinia chrysanthemi | Bact. gram-neg inner | 5 | 20 | 35.0 ± 0.8 | 0 ± 1 | -156.4 |
| 1.1.26.02. | Ligand gated ion channel, active conformation | 3eam | Gloeobacter violaceus | Bact. gram-neg inner | 5 | 20 | 32.5 ± 1.6 | 0 ± 1 | -196.6 |
