PDB ID or protein name
See list of these PDB codes

1.1.25. Major Facilitator Superfamily (MFS) (8 families) 2.A.1 (TCDB) CL0015, PDBsum (33 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
1.1.25.01. Glycerol-3-phosphate transporter glpT 1pw4 Escherichia coli Bact. Gram-neg inner 1 12 31.2 ± 1.4 1 ± 7 -92.5
1.1.25.02. Lactose permease lacY, structure at acidic pH 2cfp Escherichia coli Bact. Gram-neg inner 1 12 31.1 ± 1.4 2 ± 2 -85.4
1.1.25.02. Lactose permease lacY, conformation 1 2cfq Escherichia coli Bact. Gram-neg inner 1 12 31.9 ± 1.1 5 ± 1 -87.9
1.1.25.02. Lactose/galactose transporter, LacY 4oaa Escherichia coli Bact. Gram-neg inner 1 12 32.6 ± 1.6 2 ± 2 -101.7
1.1.25.02. Lactose permease lacY, conformation 2 2v8n Escherichia coli Bact. Gram-neg inner 1 12 31.8 ± 0.8 5 ± 0 -86.4
1.1.25.02. Lactose permease lacY, conformation 3 1pv6 Escherichia coli Bact. Gram-neg inner 1 12 31.8 ± 1.2 5 ± 0 -89.1
1.1.25.02. Lactose permease lacY, conformation 4 2y5y Escherichia coli Bact. Gram-neg inner 1 12 31.8 ± 1.3 4 ± 1 -89.0
1.1.25.03. Multidrug transporter EmrD 2gfp Escherichia coli Bact. Gram-neg inner 1 12 31.6 ± 1.5 9 ± 0 -58.0
1.1.25.03. Arginine/agmatine antiporter (AdiC), outward-facing conformation 3h5m Torpedo californica Vesicle 2 26 29.0 ± 0.8 0 ± 0 -128.9
1.1.25.03. Transporter YajR 3wdo Escherichia coli Bact. Gram-neg inner 1 12 31.0 ± 1.4 2 ± 0 -81.8
1.1.25.04. L-fucose-proton symporter fucP 3o7q Escherichia coli Bact. Gram-neg inner 1 12 30.7 ± 1.3 6 ± 0 -85.3
1.1.25.05. Glutathione uptake transporter 2xut Shewanella oneidensis Bact. Gram-neg inner 1 14 30.9 ± 1.4 10 ± 0 -102.5
1.1.25.05. Bacterial proton:oligopeptide symporter, structure 1 4lep Shewanella oneidensis Bact. Gram-neg inner 1 14 29.4 ± 0.6 7 ± 0 -89.1
1.1.25.05. Proton-dependent oligopeptide transporter, conformation 1 4ikv Geobacillus kaustophilus Bact. Gram-pos plas. 1 14 30.8 ± 1.5 5 ± 0 -110.9
1.1.25.05. Proton-dependent oligopeptide transporter, conformation 2 4iky Geobacillus kaustophilus Bact. Gram-pos plas. 1 14 31.8 ± 1.3 4 ± 0 -115.6
1.1.25.05. Proton-dependent oligopeptide transporter, conformation 3 4ikx Geobacillus kaustophilus Bact. Gram-pos plas. 1 14 31.0 ± 1.0 10 ± 0 -115.9
1.1.25.05. Nitrate transporter NRT1.1 4cl4 Arabidopsis thaliana Eukaryo. plasma 1 12 31.6 ± 1.6 7 ± 0 -76.5
1.1.25.05. Nitrate transporter NRT1/ PTR 4oh3 Arabidopsis thaliana Eukaryo. plasma 2 24 29.0 ± 0.9 0 ± 0 -106.0
1.1.25.05. Di-or tripeptide:H+ symporter, inward open conformation 4aps Streptococcus thermophilus Bact. Gram-pos plas. 1 14 31.8 ± 0.7 13 ± 0 -114.6
1.1.25.05. Di-or tripeptide:H+ symporter, inward open, peptide-bound 4d2d Streptococcus thermophilus Bact. Gram-pos plas. 1 14 31.0 ± 1.1 7 ± 0 -109.9
1.1.25.05. Bacterial proton:oligopeptide symporter, structure 2 4tpg Shewanella oneidensis Bact. Gram-neg inner 14 14 30.8 ± 1.0 9 ± 0 -100.8
1.1.25.05. Bacterial proton:oligopeptide symporter, structure 3 4tpj Shewanella oneidensis Bact. Gram-neg inner 1 14 30.6 ± 0.9 9 ± 0 -90.0
1.1.25.05. Dipeptide permease D 4q65 Escherichia coli Bact. Gram-neg inner 14 1 30.2 ± 0.8 7 ± 1 -101.4
1.1.25.06. Phosphate transporter 4j05 Acanthamoeba culbertsoni Eukaryo. plasma 1 12 30.0 ± 0.5 14 ± 0 -84.2
1.1.25.06. D-xylose-proton symporter xylE, conformation 1 4gc0 Escherichia coli Bact. Gram-neg inner 1 12 30.2 ± 0.9 1 ± 0 -90.2
1.1.25.06. D-xylose-proton symporter xylE, conformation 2 4ja3 Escherichia coli Bact. Gram-neg inner 1 12 29.8 ± 1.0 4 ± 1 -87.6
1.1.25.06. D-xylose-proton symporter xylE, conformation 3 4ja4 Escherichia coli Bact. Gram-neg inner 1 12 28.2 ± 1.3 0 ± 0 -82.8
1.1.25.06. Bicyclomycin resistance protein TcaB 4lds Staphylococcus epidermidis Bact. Gram-pos plas. 1 12 31.8 ± 1.6 4 ± 0 -87.1
1.1.25.06. Glucose transporter type 1, GLUT1 4pyp Homo sapiens Eukaryo. plasma 1 12 31.8 ± 0.7 6 ± 0 -96.2
1.1.25.06. D-xylose-proton symporter xylE, conformation 4 4qiq Escherichia coli Bact. Gram-neg inner 1 12 29.8 ± 1.8 1 ± 1 -72.6
1.1.25.07. Nitrite exporter NarU 4iu9 Escherichia coli Bact. Gram-neg inner 1 12 31.0 ± 1.2 4 ± 0 -88.1
1.1.25.07. Nitrate/nitrite exchanger NarK 4jr9 Escherichia coli Bact. Gram-neg inner 1 12 29.6 ± 1.0 8 ± 0 -86.2
1.1.25.08. Na+/melibiose symporter 4m64 Salmonella typhimurium Bact. Gram-neg inner 1 12 30.4 ± 1.3 11 ± 0 -64.9