Superfamily » 3.1.11. Peptide hormones (4 families) - Orientations of Proteins in Membranes (OPM) database

Type:3. Peptides (4 classes)
Class:3.1. Alpha-helical peptides (32 superfamilies)
Superfamily:3.1.11. Peptide hormones (4 families)
Family:
1. 3.1.11.01.
  Neuropeptide Y family PF00159, PDBsum
  Neuropeptide F
  
  Moniezia expansa (Sheep tapeworm)
  (1k8v)
  
  Neuropeptide Y
  
  Homo sapiens
  (1ron)
  
  Neuropeptide Y analogue
  
  Sus scrofa
  (1tz4, 1fvn, 1icy)
  
  Pancreatic hormone
  
  Bos taurus
  (1v1d, 1bba, 1fjv)
  
  Meleagris gallopavo
  (1ppt, 2bf9, 2h3s, 2h4b)
  
  Peptide YY
  
  Homo sapiens
  (2dez, 1qfa, 2df0, 2l60)
  
  Sus scrofa
  (1ru5, 1qbf, 1ruu, 2oon, 2oop, 2rlk)
2. 3.1.11.02.
  Glucagon family PF00123, PDBsum
  Extendin-4
  
  Heloderma suspectum
  (1jrj, 3c59, 3c5t)
  
  Extendin-4, with extracellular domain of glucagon-like peptide-1 GPCR
  
  Heloderma suspectum
  (3c59, 1jrj, 3c5t)
  
  Gastric inhibitory polypeptide, complex with N-terminal domain of GPCR
  
  Homo sapiens
  (2qkh, 1t5q, 2b4n, 2l70, 2l71, 2obu)
  
  Glucagon
  
  Sus scrofa
  (1gcn)
  
  Glucagon analog
  
  Homo sapiens
  (1bh0, 1nau, 2g49)
  
  Glucagon analog, lipidated
  
  Homo sapiens
  (2m5p, 2m5q)
  
  Glucagon-like peptide 1, in complex with extracellular domain of its GPCR
  
  Homo sapiens
  (3iol, 1d0r)
  
  Glucagon-like peptide 2
  
  Homo sapiens
  (2l64, 2l63)
  
  Pituitary adenylate cyclase activating polypeptide (PACAP)-38
  
  Homo sapiens
  (2d2p, 1gea, 2jod)
  
  Vasoactive intestinal peptide
  
  Homo sapiens
  (2rrh, 2rri)
3. 3.1.11.03.
  Motilin family PF04644, PDBsum
  Motilin
  
  Homo sapiens
  (1lbj)
  
  Obestatin
  
  Mus musculus
  (2jsi, 2jsh, 2jsj)
4. 3.1.11.04.
  Orexin PF02072, PDBsum
  Orexin-A
  
  Homo sapiens
  (1wso, 1cq0, 1r02)

3.1.11. Peptide hormones (4 families) (20 proteins)

Family	Protein Name	PDB ID	Species	Localization	Num. Subunits	Hydrophobic Thickness or Depth (Å)	Tilt Angle (°)	ΔG_transfer (kcal/mol)
3.1.11.01.	Neuropeptide Y analogue	1tz4	Sus scrofa	Secreted	1	5.1 ± 1.0	88 ± 8	-6.1
3.1.11.01.	Neuropeptide Y	1ron	Homo sapiens	Secreted	1	7.9 ± 1.6	74 ± 10	-8.6
3.1.11.01.	Peptide YY	2dez	Homo sapiens	Secreted	1	4.0 ± 0.2	84 ± 2	-5.9
3.1.11.01.	Neuropeptide F	1k8v	Moniezia expansa (Sheep tapeworm)	Secreted	1	2.9 ± 1.1	68 ± 9	-7.0
3.1.11.01.	Peptide YY	1ru5	Sus scrofa	Secreted	1	5.1 ± 1.2	83 ± 3	-5.3
3.1.11.01.	Pancreatic hormone	1ppt	Meleagris gallopavo	Secreted	1	3.5 ± 2.9	90 ± 27	-3.9
3.1.11.01.	Pancreatic hormone	1v1d	Bos taurus	Secreted	1	1.2 ± 3.0	79 ± 32	-1.9
3.1.11.02.	Glucagon-like peptide 1, in complex with extracellular domain of its GPCR	3iol	Homo sapiens	Secreted	2	2.8 ± 04.0	70 ± 1	-6.7
3.1.11.02.	Glucagon	1gcn	Sus scrofa	Secreted	1	5.3 ± 1.0	78 ± 12	-6.6
3.1.11.02.	Glucagon-like peptide 2	2l64	Homo sapiens	Secreted	1	3.9 ± 0.3	90 ± 5	-10.8
3.1.11.02.	Glucagon analog	1bh0	Homo sapiens	Secreted	1	4.9 ± 4.2	78 ± 2	-6.1
3.1.11.02.	Glucagon analog, lipidated	2m5p	Homo sapiens	Secreted	1	5.2 ± 0.6	85 ± 4	-6.0
3.1.11.02.	Gastric inhibitory polypeptide, complex with N-terminal domain of GPCR	2qkh	Homo sapiens	Secreted	2	6.3 ± 3.2	64 ± 23	-5.9
3.1.11.02.	Vasoactive intestinal peptide	2rrh	Homo sapiens	Secreted	1	4.1 ± 0.3	79 ± 9	-5.7
3.1.11.02.	Pituitary adenylate cyclase activating polypeptide (PACAP)-38	2d2p	Homo sapiens	Secreted	1	3.9 ± 4.0	90 ± 0	-6.8
3.1.11.02.	Extendin-4	1jrj	Heloderma suspectum	Secreted	1	1.7 ± 0.8	79 ± 8	-5.0
3.1.11.02.	Extendin-4, with extracellular domain of glucagon-like peptide-1 GPCR	3c59	Heloderma suspectum	Secreted	2	1.9 ± 0.2	64 ± 0	-6.5
3.1.11.03.	Motilin	1lbj	Homo sapiens	Secreted	1	8.6 ± 1.6	51 ± 18	-4.9
3.1.11.03.	Obestatin	2jsi	Mus musculus	Secreted	1	2.0 ± 3.3	85 ± 13	-3.1
3.1.11.04.	Orexin-A	1wso	Homo sapiens	Secreted	1	6.4 ± 1.7	72 ± 14	-5.5