- Type:1. Transmembrane (2 classes)
- Class:1.1. Alpha-helical transmembrane (54 superfamilies)
- Superfamily:1.1.15. Resistance-nodulation-cell division (1 family) 2.A.6 (TCDB)
- Family:
- 1.1.15.01.Multidrug efflux transporter 2.A.6 (TCDB)
Multidrug efflux transporter AcrB
Escherichia coli(2gif, 1iwg, 1oy6, 1oy8, 1oy9, 1oyd, 1oye, 1t9t, 1t9u, 1t9v, 1t9w, 1t9x, 1t9y, 2dhh, 2dr6, 2drd, 2hqc, 2hqd, 2hqf, 2hqg, 2hrt, 2i6w, 2j8s, 2rdd, 2w1b, 3d9b)
Multidrug efflux transporter AcrB with an additional TM helix
Multidrug exporter MexB
1.1.15. Resistance-nodulation-cell division (1 family) 2.A.6 (TCDB) (3 proteins)
| Family | Protein Name | PDB ID | Species | Localization | Num. Subunits | Num. TM Sec. Structs. | Hydrophobic Thickness or Depth (Å) | Tilt Angle (°) | ΔGtransfer (kcal/mol) |
|---|---|---|---|---|---|---|---|---|---|
| 1.1.15.01. | Multidrug efflux transporter AcrB | 2gif | Escherichia coli | Bact. gram-neg inner | 3 | 36 | 27.5 ± 0.8 | 2 ± 2 | -212.8 |
| 1.1.15.01. | Multidrug efflux transporter AcrB with an additional TM helix | 2rdd | Escherichia coli | Bact. gram-neg inner | 6 | 39 | 26.5 ± 0.8 | 0 ± 1 | -239.0 |
| 1.1.15.01. | Multidrug exporter MexB | 2v50 | Pseudomonas aeruginosa | Bact. gram-neg inner | 3 | 36 | 27.5 ± 0.8 | 0 ± 1 | -189.7 |
