- Type:1. Transmembrane (2 classes)
- Class:1.1. Alpha-helical transmembrane (54 superfamilies)
- Superfamily:1.1.40. MAPEG (Eicosanoid and Glutathione metabolism proteins) (1 family)
- Family:
- 1.1.40.01.MAPEG domain
FLAP protein (5-lipoxygenase activator)
Lekotriene C4 synthase
Microsomal glutathione S-transferase 1
Microsomal prostaglandin E synthase 1
1.1.40. MAPEG (Eicosanoid and Glutathione metabolism proteins) (1 family) (4 proteins)
| Family | Protein Name | PDB ID | Species | Localization | Num. Subunits | Num. TM Sec. Structs. | Hydrophobic Thickness or Depth (Å) | Tilt Angle (°) | ΔGtransfer (kcal/mol) |
|---|---|---|---|---|---|---|---|---|---|
| 1.1.40.01. | Lekotriene C4 synthase | 2uuh | Homo sapiens | Endoplasm. reticulum | 3 | 12 | 26.3 ± 1.2 | 0 ± 1 | -58.2 |
| 1.1.40.01. | Microsomal glutathione S-transferase 1 | 2h8a | Rattus norvegicus | Endoplasm. reticulum | 3 | 12 | 29.5 ± 1.7 | 0 ± 1 | -72.2 |
| 1.1.40.01. | FLAP protein (5-lipoxygenase activator) | 2q7r | Homo sapiens | Endoplasm. reticulum | 3 | 12 | 22.5 ± 4.7 | 0 ± 2 | -81.4 |
| 1.1.40.01. | Microsomal prostaglandin E synthase 1 | 3dww | Homo sapiens | Endoplasm. reticulum | 3 | 12 | 33.4 ± 1.8 | 1 ± 3 | -113.3 |
