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LIPID COMPOSITION ATLAS
Protein Classification
Types
(3 types)
Classes
(11 classes)
Superfamilies
(393 superfamilies)
Families
(668 families)
Species
(539 species)
Localization
(24 types)
All proteins in OPM
(2185 proteins)
Protein Links
PDB Sum
,
PDB
,
OCA
,
MPKS
,
PDBTM
,
MPDB
,
CGDB
Type:
3. Peptides
(4 classes)
Class:
3.1. Alpha-helical peptides
(32 superfamilies)
Superfamily:
3.1.28. Amphibian antimicrobial peptides (6 families)
Family:
3.1.28.06.
Magainin
Magainin 2
Xenopus laevis
(
2mag
, 1dum, 1f0d, 1f0f, 1f0g, 1f0h)
Magainin analogue, MSI-594
Designed proteins
(
2k98
)
3.1.28.01.
Dermaseptin
1.C.52 (TCDB)
PF12121
,
PDBsum
Dermaseptin-4
Phyllomedusa sauvagei (Sauvage's leaf frog)
(
2dd6
, 2dcx)
Dermatistinctin K
Phyllomedusa distincta
(
2k9b
, 2jx6)
3.1.28.05.
Maculatin
1.C.76 (TCDB)
PF08256
,
PDBsum
Aurein 1.2
Litoria aurea
(
1vm5
)
Aurein 1.2 analogue
Designed proteins
(
2f3a
)
3.1.28.02.
Alyteserin
Alyteserin-1C
Alytes obstetricans
(
2l5r
)
3.1.28.03.
Bombinin
PF05298
,
PDBsum
Bombinin-H5
Bombina variegata (Yellow-bellied toad)
(
2ap8
, 2ap7)
3.1.28.04.
Brevinin/gaegurin
PF03032
,
PDBsum
Gaegurin-4
Glandirana rugosa (Japanese wrinkled frog)
(
2g9l
)
Phylloseptin-1
Phyllomedusa hypochondrialis (Orange-legged leaf frog)
(
2jq0
)
Phylloseptin-2
Phyllomedusa hypochondrialis (Orange-legged leaf frog)
(
2jpy
)
Phylloseptin-3
Phyllomedusa hypochondrialis (Orange-legged leaf frog)
(
2jq1
)
Ranatuerin 1T
Rana temporaria
(
2k10
)
See list of these PDB codes
3.1.28. Amphibian antimicrobial peptides (6 families) (13 proteins)
Family
Protein Name
PDB ID
Species
Localization
Num. Subunits
Num. TM Sec. Structs.
Hydrophobic Thickness or Depth (Å)
Tilt Angle (°)
ΔG
transfer
(kcal/mol)
3.1.28.01.
Dermatistinctin K
2k9b
Phyllomedusa distincta
Secreted
1
0
4.6 ± 1.0
90 ± 10
-7.0
3.1.28.01.
Dermaseptin-4
2dd6
Phyllomedusa sauvagei (Sauvage's leaf frog)
Secreted
1
0
4.2 ± 1.6
76 ± 6
-7.0
3.1.28.02.
Alyteserin-1C
2l5r
Alytes obstetricans
Secreted
1
0
8.7 ± 4.1
81 ± 0
-14.1
3.1.28.03.
Bombinin-H5
2ap8
Bombina variegata (Yellow-bellied toad)
Secreted
1
0
8.6 ± 4.2
77 ± 3
-10.6
3.1.28.04.
Phylloseptin-1
2jq0
Phyllomedusa hypochondrialis (Orange-legged leaf frog)
Secreted
1
0
9.5 ± 1.4
76 ± 7
-13.5
3.1.28.04.
Ranatuerin 1T
2k10
Rana temporaria
Secreted
1
0
10.4 ± 1.2
74 ± 5
-14.3
3.1.28.04.
Phylloseptin-2
2jpy
Phyllomedusa hypochondrialis (Orange-legged leaf frog)
Secreted
1
0
5.8 ± 1.3
86 ± 4
-15.2
3.1.28.04.
Gaegurin-4
2g9l
Glandirana rugosa (Japanese wrinkled frog)
Secreted
1
0
8.9 ± 4.0
71 ± 3
-9.6
3.1.28.04.
Phylloseptin-3
2jq1
Phyllomedusa hypochondrialis (Orange-legged leaf frog)
Secreted
1
0
6.4 ± 0.8
74 ± 9
-9.5
3.1.28.05.
Aurein 1.2
1vm5
Litoria aurea
Secreted
1
0
9.5 ± 1.8
63 ± 14
-9.7
3.1.28.05.
Aurein 1.2 analogue
2f3a
Designed proteins
Undefined
1
0
3.0 ± 1.6
88 ± 24
-11.7
3.1.28.06.
Magainin 2
2mag
Xenopus laevis
Secreted
1
0
10.1 ± 0.9
81 ± 14
-13.7
3.1.28.06.
Magainin analogue, MSI-594
2k98
Designed proteins
Undefined
1
0
3.2 ± 0.2
86 ± 2
-8.9
Copyright © 2005-2013
Andrei Lomize
,
Mikhail Lomize
and
Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA