PDB ID or protein name
See list of these PDB codes

1.1.01. Rhodopsin-like receptors and pumps (6 families) CL0192, PDBsum (106 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
1.1.01.01. Sensory rhodopsin, monomer 1xio Nostoc sp. Bact. Gram-neg inner 1 7 31.9 ± 1.5 13 ± 4 -63.1
1.1.01.01. Bacteriorhodopsin 1m0l Halobacterium salinarum Archaebac. 3 21 31.8 ± 1.1 0 ± 1 -121.1
1.1.01.01. Sensory rhodopsin II, tetramer 1h2s Natronomonas pharaonis Archaebac. 4 18 30.5 ± 1.1 0 ± 0 -123.4
1.1.01.01. Halorhodopsin 1e12 Halobacterium salinarum Archaebac. 3 21 31.8 ± 1.4 0 ± 1 -126.7
1.1.01.01. Archaerhodopsin-1 1uaz Halobacterium sp. Archaebac. 1 7 31.8 ± 1.3 9 ± 2 -65.3
1.1.01.01. Bacteriorhodopsin, K state, with lipids 1iw6 Halobacterium salinarum Archaebac. 3 21 30.0 ± 0.6 0 ± 0 -112.6
1.1.01.01. Bacteriorhodopsin, trimer, complex with annular lipids 2zzl Halobacterium salinarum Archaebac. 3 21 29.8 ± 0.6 0 ± 0 -119.0
1.1.01.01. Sensory rhodopsin II, monomer 1h68 Natronomonas pharaonis Archaebac. 1 7 30.3 ± 1.5 15 ± 2 -60.0
1.1.01.01. Bacteriorhodopsin, monomer 1py6 Halobacterium salinarum Archaebac. 1 7 29.6 ± 2.2 24 ± 8 -59.7
1.1.01.01. Archaerhodopsin-2, monomer 1vgo Halobacterium sp. Archaebac. 1 7 30.7 ± 1.3 18 ± 2 -73.1
1.1.01.01. Proton-pumping rhodopsin-2 from algae 3am6 Acetabularia acetabulum Eukaryo. plasma 1 7 31.2 ± 1.6 10 ± 1 -65.4
1.1.01.01. Bacteriorhodopsin, from cubic phase 1ap9 Halobacterium salinarum Archaebac. 3 21 30.6 ± 1.2 0 ± 0 -97.8
1.1.01.01. Archaerhodopsin-2, trimeric 2ei4 Halobacterium sp. Archaebac. 3 21 30.5 ± 1.2 0 ± 1 -143.9
1.1.01.01. Xanthorhodopsin 3ddl Salinibacter ruber Bact. Gram-neg inner 1 7 28.2 ± 1.8 11 ± 0 -60.7
1.1.01.01. Halorhodopsin 3a7k Natronomonas pharaonis Archaebac. 3 21 33.8 ± 1.4 1 ± 0 -141.3
1.1.01.01. Green-light absorbing proteorhodopsin 2l6x Gamma-proteobacterium Bact. Gram-neg inner 1 7 27.8 ± 1.3 18 ± 1 -55.2
1.1.01.01. Chimaera of channelrhodopsins 1 and 2 3ug9 Chlamydomonas reinhardtii Eukaryo. plasma 2 14 31.0 ± 1.2 0 ± 0 -100.3
1.1.01.01. Bacteriorhodopsin, different loop conformaton 1fbk Halobacterium salinarum Archaebac. 3 21 30.0 ± 1.2 0 ± 0 -127.8
1.1.01.01. Deltarhodopsin 4fbz Haloterrigena thermotolerans Archaebac. 3 21 31.6 ± 0.8 0 ± 0 -110.6
1.1.01.01. Blue-light absorbing proteorhodopsin 4knf Gamma-proteobacterium Bact. Gram-neg inner 5 35 28.4 ± 1.5 1 ± 1 -159.6
1.1.01.01. Proteorhodopsin 4jq6 Gamma-proteobacterium Bact. Gram-neg inner 6 42 28.4 ± 1.3 0 ± 0 -188.5
1.1.01.01. Halorhodopsin, different conformation 3vvk Natronomonas pharaonis Archaebac. 3 21 33.6 ± 1.1 0 ± 0 -140.5
1.1.01.01. Proteorhodopsin 4hyj Exiguobacterium sibiricum Bact. Gram-pos plas. 1 7 30.0 ± 1.6 15 ± 7 -56.8
1.1.01.01. Sensory rhodopsin, trimer 2m3g Nostoc sp. Bact. Gram-neg inner 3 21 31.8 ± 0.8 2 ± 0 -132.8
1.1.01.01. Cruxrhodopsin-3 4jr8 Haloarcula vallismortis Archaebac. 3 21 31.8 ± 1.2 0 ± 0 -130.4
1.1.01.01. Sensory rhodopsin, dimer 4tl3 Nostoc sp. Bact. Gram-neg inner 2 17 30.6 ± 1.1 0 ± 0 -116.0
1.1.01.01. Bacteriorhodopsin-I 4pxk Haloarcula marismortui Archaebac. 1 7 31.8 ± 1.4 11 ± 1 -72.7
1.1.01.01. Sodium pumping rhodopsin, NaR, monomer 4xtl Dokdonia eikasta Bact. Gram-neg inner 1 7 29.8 ± 1.9 20 ± 2 -57.4
1.1.01.01. Sodium pumping rhodopsin, NaR, pentamer 4xto Dokdonia eikasta Bact. Gram-neg inner 5 35 29.8 ± 0.5 0 ± 0 -170.3
1.1.01.01. Sodium pumping rhodopsin, NaR, dimer 3x3b Dokdonia eikasta Bact. Gram-neg inner 2 14 29.8 ± 0.9 0 ± 0 -87.5
1.1.01.01. Rhodopsin I 3wt9 Acetabularia acetabulum Eukaryo. plasma 1 7 31.8 ± 1.8 8 ± 1 -65.4
1.1.01.02. Opsin, active, retinal-free state, dimer 3cap Bos taurus Eukaryo. plasma 2 14 30.8 ± 1.1 0 ± 0 -130.1
1.1.01.02. Rhodopsin, inactive, complex with inverse agonist, 11-cis retinal 1gzm Bos taurus Eukaryo. plasma 1 7 32.2 ± 1.5 11 ± 1 -75.6
1.1.01.02. Squid rhodopsin, inactive, complex with inverse agonist 11-cis retinal, dimer 2z73 Todarodes pacificus Eukaryo. plasma 2 14 32.9 ± 1.0 0 ± 1 -143.3
1.1.01.02. Rhodopsin, constitutively active mutant (metarhodopsin II), dimer 2x72 Bos taurus Eukaryo. plasma 2 14 30.0 ± 0.6 0 ± 0 -132.0
1.1.01.02. Beta-2 adrenergic receptor, active state, complex with G-protein 3sn6 Homo sapiens Eukaryo. plasma 1 7 31.0 ± 1.6 8 ± 1 -68.2
1.1.01.02. Adenosine receptor A2a, inactive state, engineered, complex with inverse agonist 3pwh Homo sapiens Eukaryo. plasma 1 7 31.0 ± 1.3 9 ± 0 -67.3
1.1.01.02. Rhodopsin, partially active, photobleached 2i37 Bos taurus Eukaryo. plasma 1 7 31.9 ± 1.5 5 ± 1 -79.1
1.1.01.02. Rhodopsin, inactive state, a dimer 2i36 Bos taurus Eukaryo. plasma 2 14 30.0 ± 1.4 4 ± 4 -125.6
1.1.01.02. Melanocortin-4 receptor model (active state) with agonist NDP-MSH 2iqr Homo sapiens Eukaryo. plasma 1 7 33.5 ± 2.0 24 ± 0 -60.6
1.1.01.02. Melanocortin-4 receptor model (inactive state) with antagonist AGRP 2iqv Homo sapiens Eukaryo. plasma 1 7 31.9 ± 1.1 19 ± 0 -49.1
1.1.01.02. Opioid mu receptor 4dkl Mus musculus Eukaryo. plasma 2 14 32.0 ± 1.0 5 ± 0 -134.7
1.1.01.02. Beta-2 adrenergic receptor, inactive state, dimer 2rh1 Homo sapiens Eukaryo. plasma 2 14 31.8 ± 0.9 0 ± 1 -143.2
1.1.01.02. Adenosine receptor A2a, inactive state, complex with antagonist 3eml Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 8 ± 12 -66.1
1.1.01.02. TM1-TM2 fragment of fungal STE2 receptor 2k9p Saccharomyces cerevisiae Eukaryo. plasma 1 2 29.8 ± 3.1 21 ± 4 -10.5
1.1.01.02. Squid rhodopsin, inactive, complex with inverse agonist 11-cis retinal 2ziy Todarodes pacificus Eukaryo. plasma 1 7 32.9 ± 1.7 11 ± 2 -75.1
1.1.01.02. C-X-C chemokine receptor type 4, inactive, complex with antagonist 3oe6 Homo sapiens Eukaryo. plasma 1 7 35.3 ± 2.5 8 ± 7 -79.7
1.1.01.02. C-X-C chemokine receptor type 4, inactive, with cyclic peptide antagonist 3oe0 Homo sapiens Eukaryo. plasma 2 14 32.2 ± 2.0 5 ± 6 -133.2
1.1.01.02. C-X-C chemokine receptor type 4, inactive, dimer, complex with antagonist 3odu Homo sapiens Eukaryo. plasma 2 14 31.2 ± 1.1 0 ± 0 -129.5
1.1.01.02. Dopamine D3 receptor 3pbl Homo sapiens Eukaryo. plasma 1 7 33.0 ± 1.8 8 ± 1 -56.6
1.1.01.02. Beta-1 adrenergic receptor, inactive, complex with agonist 2y02 Meleagris gallopavo Eukaryo. plasma 1 7 31.4 ± 1.3 2 ± 0 -76.9
1.1.01.02. Rhodopsin, inactive, conformation 2 3oax Bos taurus Eukaryo. plasma 1 7 30.9 ± 1.4 11 ± 0 -73.6
1.1.01.02. Beta-2 adrenergic receptor, active state, complex with antibody 3p0g Homo sapiens Eukaryo. plasma 1 7 30.1 ± 1.4 9 ± 1 -62.9
1.1.01.02. Rhodopsin, active (metarhodopsin II), complex with peptide of transducin 3pqr Bos taurus Eukaryo. plasma 1 7 31.8 ± 1.1 9 ± 1 -78.3
1.1.01.02. Rhodopsin, active (metarhodopsin II), without transducin peptide 3pxo Bos taurus Eukaryo. plasma 2 14 31.8 ± 1.2 0 ± 0 -125.4
1.1.01.02. Adenosine receptor A2a, partially active state, complex with agonist 3qak Homo sapiens Eukaryo. plasma 1 7 29.8 ± 1.2 9 ± 0 -70.0
1.1.01.02. Adenosine receptor A2a, partially active state, engineered, complex with agonist 2ydv Homo sapiens Eukaryo. plasma 1 7 31.0 ± 1.3 10 ± 0 -61.4
1.1.01.02. Beta-1 adrenergic receptor, inactive, complex with antagonist 2ycw Meleagris gallopavo Eukaryo. plasma 1 7 32.2 ± 1.3 2 ± 0 -77.8
1.1.01.02. Histamine H1 receptor 3rze Homo sapiens Eukaryo. plasma 1 7 32.0 ± 1.4 1 ± 1 -72.4
1.1.01.02. Beta-2 adrenergic receptor, inactive state 4gbr Homo sapiens Eukaryo. plasma 1 7 31.6 ± 1.3 7 ± 1 -71.7
1.1.01.02. Beta-1 adrenergic receptor, inactive, multiple mutations 2vt4 Meleagris gallopavo Eukaryo. plasma 1 7 32.8 ± 1.6 3 ± 1 -74.6
1.1.01.02. Muscarinic acetylcholine receptor M2, inactive 3uon Homo sapiens Eukaryo. plasma 1 7 31.8 ± 2.1 4 ± 2 -68.5
1.1.01.02. Adenosine receptor A2a, complex with antibody 3vga Homo sapiens Eukaryo. plasma 1 7 30.4 ± 1.4 7 ± 2 -62.8
1.1.01.02. Sphingosine 1-phosphate receptor 1 3v2y Homo sapiens Eukaryo. plasma 1 7 32.2 ± 1.4 10 ± 0 -65.9
1.1.01.02. Muscarinic acetylcholine receptor M3, structure 1 4daj Rattus norvegicus Eukaryo. plasma 1 7 32.2 ± 1.2 5 ± 0 -75.8
1.1.01.02. Opioid kappa receptor 4djh Homo sapiens Eukaryo. plasma 2 14 32.0 ± 0.8 1 ± 0 -146.6
1.1.01.02. Adenosine receptor A2a, complex with antagonist 3uza Homo sapiens Eukaryo. plasma 1 7 31.6 ± 0.6 8 ± 1 -72.5
1.1.01.02. Nociceptin receptor 4ea3 Homo sapiens Eukaryo. plasma 1 7 32.0 ± 1.2 7 ± 1 -65.6
1.1.01.02. Opioid delta receptor 4ej4 Mus musculus Eukaryo. plasma 1 7 34.4 ± 0.8 11 ± 6 -73.2
1.1.01.02. Adenosine receptor A2a, inactive state, with annular lipids 4eiy Homo sapiens Eukaryo. plasma 1 7 32.2 ± 1.2 18 ± 0 -70.4
1.1.01.02. Neurotensin receptor type 1, conformation 1 4grv Rattus norvegicus Eukaryo. plasma 1 7 31.6 ± 1.1 4 ± 1 -75.1
1.1.01.02. C-X-C chemokine receptor type 1 2lnl Homo sapiens Eukaryo. plasma 1 7 30.2 ± 0.9 19 ± 6 -54.4
1.1.01.02. Thrombin (proteinase-activated) receptor 1, PAR1 3vw7 Homo sapiens Eukaryo. plasma 1 7 33.4 ± 1.9 1 ± 0 -72.2
1.1.01.02. Beta-1 adrenergic receptor, inactive, dimer 4gpo Meleagris gallopavo Eukaryo. plasma 2 14 30.8 ± 1.2 0 ± 0 -144.8
1.1.01.02. 5-hydroxytryptamine receptor 2B 4ib4 Homo sapiens Eukaryo. plasma 1 7 34.0 ± 2.3 16 ± 2 -69.2
1.1.01.02. 5-hydroxytryptamine receptor 1B, conformation 1 4iar Homo sapiens Eukaryo. plasma 1 7 33.6 ± 1.8 7 ± 1 -76.4
1.1.01.02. 5-hydroxytryptamine receptor 1B, conformation 2 4iaq Homo sapiens Eukaryo. plasma 1 7 34.4 ± 1.7 6 ± 1 -77.4
1.1.01.02. Rhodopsin, inactive, conformation 3 1u19 Bos taurus Eukaryo. plasma 1 7 31.2 ± 1.5 12 ± 1 -71.9
1.1.01.02. C-C chemokine receptor type 5 4mbs Homo sapiens Eukaryo. plasma 1 7 34.4 ± 1.5 0 ± 0 -88.8
1.1.01.02. Muscarinic acetylcholine receptor M2, active 4mqs Homo sapiens Eukaryo. plasma 1 7 32.2 ± 2.1 8 ± 3 -70.0
1.1.01.02. Opioid delta receptor, apo 4n6h Homo sapiens Eukaryo. plasma 1 7 34.0 ± 2.3 14 ± 0 -68.6
1.1.01.02. Neurotensin receptor type 1, conformation 2 4buo Rattus norvegicus Eukaryo. plasma 1 7 31.4 ± 1.4 6 ± 2 -62.6
1.1.01.02. P2Y purinoceptor 12 4ntj Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 9 ± 0 -79.8
1.1.01.02. P2Y purinoceptor 12 4pxz Homo sapiens Eukaryo. plasma 1 7 36.0 ± 1.9 4 ± 3 -79.5
1.1.01.02. Free fatty acid receptor 1 4phu Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.2 10 ± 1 -59.2
1.1.01.02. Opsin, complex with arrestin peptide 4pxf Bos taurus Eukaryo. plasma 1 7 31.6 ± 0.9 8 ± 1 -80.1
1.1.01.02. Muscarinic acetylcholine receptor M3, structure 2 4u15 Rattus norvegicus Eukaryo. plasma 1 7 31.8 ± 1.5 1 ± 1 -70.6
1.1.01.02. Orexin receptor type 2 4s0v Homo sapiens Eukaryo. plasma 1 7 32.0 ± 1.4 0 ± 1 -72.5
1.1.01.02. Opioid delta receptor, complex with peptide 4rwa Homo sapiens Eukaryo. plasma 1 7 36.2 ± 2.1 12 ± 0 -72.9
1.1.01.02. C-X-C chemokine receptor type 4, complex with peptide 4rws Homo sapiens Eukaryo. plasma 1 7 33.8 ± 1.5 9 ± 1 -76.9
1.1.01.02. Viral GPCR US28, complex with fractalkine 4xt3 Human herpesvirus Eukaryo. plasma 1 7 32.8 ± 1.7 2 ± 2 -69.1
1.1.01.02. Viral GPCR US28, complex with fractalkine and nanobody 4xt1 Human herpesvirus Eukaryo. plasma 1 7 31.6 ± 1.2 4 ± 2 -64.2
1.1.01.02. P2Y purinoceptor 1, conformation 1 4xnv Homo sapiens Eukaryo. plasma 1 7 32.6 ± 1.7 6 ± 1 -70.3
1.1.01.02. P2Y purinoceptor 1, conformation 2 4xnw Homo sapiens Eukaryo. plasma 1 7 33.4 ± 1.3 5 ± 1 -72.0
1.1.01.02. Adenosine receptor A2a, active-like, complex with agonist 4uhr Homo sapiens Eukaryo. plasma 7 0 30.6 ± 1.7 9 ± 1 -60.8
1.1.01.02. Type-1 angiotensin II receptor 4yay Homo sapiens Eukaryo. plasma 1 7 35.8 ± 0.4 13 ± 1 -71.0
1.1.01.03. Ectodomain of G-protein coupled receptor Mth 1fjr Drosophila melanogaster Eukaryo. plasma 1 0 1.8 ± 1.5 56 ± 13 -4.3
1.1.01.03. Corticotropin-releasing factor receptor 1 4k5y Homo sapiens Eukaryo. plasma 1 7 31.8 ± 1.1 16 ± 3 -71.4
1.1.01.03. Glucagon receptor 4l6r Homo sapiens Eukaryo. plasma 1 7 28.8 ± 1.8 20 ± 0 -46.7
1.1.01.04. Smoothened homolog, dimer, structure 1 4jkv Homo sapiens Eukaryo. plasma 2 14 31.9 ± 1.2 0 ± 0 -98.5
1.1.01.04. Smoothened homolog, monomer, conformation 1 4n4w Homo sapiens Eukaryo. plasma 1 7 31.6 ± 2.1 17 ± 1 -57.0
1.1.01.04. Smoothened homolog, monomer, conformation 2 4o9r Homo sapiens Eukaryo. plasma 1 7 30.6 ± 1.4 12 ± 1 -57.3
1.1.01.04. Smoothened homolog, dimer, structure 2 4qin Homo sapiens Eukaryo. plasma 2 14 31.6 ± 1.3 1 ± 1 -94.0
1.1.01.05. Metabotropic glutamate receptor 1 4or2 Homo sapiens Eukaryo. plasma 2 14 31.4 ± 0.9 1 ± 0 -117.3
1.1.01.05. Metabotropic glutamate receptor 5 4oo9 Homo sapiens Eukaryo. plasma 1 7 32.4 ± 1.2 2 ± 1 -66.3
1.1.01.06. Adiponectin receptor 1 3wxv Homo sapiens Eukaryo. plasma 1 7 32.8 ± 1.2 15 ± 1 -79.3