Superfamily » 1.1.01. Rhodopsin-like proteins (2 families) - Orientations of Proteins in Membranes (OPM) database

Type:1. Transmembrane (2 classes)
Class:1.1. Alpha-helical transmembrane (54 superfamilies)
Superfamily:1.1.01. Rhodopsin-like proteins (2 families)
Family:
1. 1.1.01.01.
  Ion-translocating microbial rhodopsin 3.E.1 (TCDB)
  Archaerhodopsin-1
  
  Halobacterium sp.
  (1uaz)
  
  Archaerhodopsin-2
  
  Halobacterium sp.
  (1vgo, 2ei4, 2z55)
  
  Archaerhodopsin-2, trimeric
  
  Halobacterium sp.
  (2ei4, 1vgo, 2z55)
  
  Bacteriorhodopsin, monomer
  
  Halobacterium salinarum
  (1py6, 1bct, 1bha, 1bhb, 1jv6, 1jv7, 1kme, 1pxr, 1pxs, 1q5i, 1q5j, 1s51, 1s52, 1s53, 1s54, 1tn0, 1tn5, 1xji, 3coc, 3cod, 3han, 3hao, 3hap, 3haq, 3har, 3has)
  
  Bacteriorhodopsin, trimer
  
  Halobacterium salinarum
  (1m0l, 1ap9, 1at9, 1bm1, 1brd, 1brr, 1brx, 1c3w, 1c8r, 1c8s, 1cwq, 1dze, 1e0p, 1f4z, 1f50, 1fbb, 1fbk, 1iw6, 1iw9, 1ixf, 1jv6, 1jv7, 1kg8, 1kg9, 1kgb, 1kme, 1l0m, 1m0k, 1m0m, 1mgy, 1o0a, 1p8h, 1p8i, 1p8u, 1pxr, 1pxs, 1py6, 1q5i, 1q5j, 1qhj, 1qko, 1qkp, 1qm8, 1r2n, 1r84, 1s51, 1s52, 1s53, 1s54, 1s8j, 1s8l, 1tn0, 1tn5, 1ucq, 1vjm, 1x0i, 1x0k, 1x0s, 1xji, 2at9, 2brd, 2i1x, 2i20, 2i21, 2ntu, 2ntw, 2zfe, 2zzl)
  
  Halorhodopsin
  
  Halobacterium salinarum
  (1e12, 2jaf, 2jag)
  
  Sensory Rhodopsin
  
  Anabaena sp.
  (1xio)
  
  Sensory rhodopsin II
  
  Natronomonas pharaonis
  (1h2s, 1gu8, 1gue, 1h68, 1jgj, 2f93, 2f95, 2rm8)
  
  Sensory rhodopsin II, monomer
  
  Natronomonas pharaonis
  (1h68, 1gu8, 1gue, 1h2s, 1jgj)
  
  Xanthorhodopsin
  
  Salinibacter ruber
  (3ddl)
2. 1.1.01.02.
  G-protein coupled receptors
  A2A adenosine receptor bound to antagonist ZM241385
  
  Homo sapiens
  (3eml)
  
  Beta1-adrenergic receptor
  
  Meleagris gallopavo
  (2vt4)
  
  Beta2-adrenergic receptor
  
  Homo sapiens
  (2rh1, 2r4r, 2r4s, 3d4s)
  
  Cholecystokinin A receptor fragment
  
  Homo sapiens
  (1d6g)
  
  Melanocortin-4 receptor model (active state) with agonist NDP-MSH
  
  Homo sapiens
  (2iqr)
  
  Melanocortin-4 receptor model (inactive state) with antagonist AGRP
  
  Homo sapiens
  (2iqv)
  
  Mu-opioid receptor model (inactive state) with antagonist
  
  Rattus norvegicus
  (2iql)
  
  Mu-opioid receptor model in active state with agonist
  
  Rattus norvegicus
  (2iqo)
  
  Opsin, complex with C-terminal peptide of Galpha subunit of transducin
  
  Bos taurus
  (3dqb, 3cap)
  
  Opsin, retinal-free state
  
  Bos taurus
  (3cap, 1f88, 1gzm, 1hzx, 1l9h, 1u19, 2g87, 2hpy, 2i35, 2i36, 2i37, 2iqk, 2j4y, 2ped, 3dqb)
  
  Rhodopsin
  
  Bos taurus
  (1gzm, 1f88, 1hzx, 1jfp, 1l9h, 1ln6, 1u19, 2g87, 2hpy, 2i35, 2i36, 2i37, 2iqk, 2ped, 3c9l, 3c9m, 3cap)
  
  Rhodopsin, a dimer
  
  Bos taurus
  (2i36, 1f88, 1gzm, 1hzx, 1l9h, 1u19, 2g87, 2hpy, 2i35, 2i37, 2iqk, 2ped, 3cap)
  
  Rhodopsin, a photobleached state
  
  Bos taurus
  (2i37, 1f88, 1gzm, 1hzx, 1l9h, 1u19, 2g87, 2hpy, 2i35, 2i36, 2iqk, 2ped, 3cap)
  
  Squid rhodopsin dimer
  
  Todarodes pacificus
  (2z73, 2ziy)
  
  TM1-TM2 fragment of fungal STE2 receptor
  
  Saccharomyces cerevisiae
  (2k9p)

1.1.01. Rhodopsin-like proteins (2 families) (25 proteins)

Family	Protein Name	PDB ID	Species	Localization	Num. Subunits	Num. TM Sec. Structs.	Hydrophobic Thickness or Depth (Å)	Tilt Angle (°)	ΔG_transfer (kcal/mol)
1.1.01.01.	Bacteriorhodopsin, trimer	1m0l	Halobacterium salinarum	Archaebac.	3	21	30.0 ± 1.1	0 ± 1	-149.5
1.1.01.01.	Sensory Rhodopsin	1xio	Anabaena sp.	Bact. gram-neg inner	1	7	31.2 ± 2.8	8 ± 6	-71.7
1.1.01.01.	Sensory rhodopsin II	1h2s	Natronomonas pharaonis	Archaebac.	4	18	29.5 ± 1.1	0 ± 2	-160.0
1.1.01.01.	Xanthorhodopsin	3ddl	Salinibacter ruber	Bact. gram-neg inner	1	7	26.0 ± 1.5	14 ± 3	-68.2
1.1.01.01.	Halorhodopsin	1e12	Halobacterium salinarum	Archaebac.	3	21	30.9 ± 1.8	0 ± 1	-151.6
1.1.01.01.	Archaerhodopsin-1	1uaz	Halobacterium sp.	Archaebac.	1	7	31.7 ± 2.2	6 ± 4	-73.9
1.1.01.01.	Sensory rhodopsin II, monomer	1h68	Natronomonas pharaonis	Archaebac.	1	7	31.6 ± 2.5	12 ± 5	-76.2
1.1.01.01.	Bacteriorhodopsin, monomer	1py6	Halobacterium salinarum	Archaebac.	1	7	31.0 ± 2.5	13 ± 6	-75.9
1.1.01.01.	Archaerhodopsin-2	1vgo	Halobacterium sp.	Archaebac.	1	7	30.8 ± 1.5	9 ± 4	-81.8
1.1.01.01.	Archaerhodopsin-2, trimeric	2ei4	Halobacterium sp.	Archaebac.	3	21	30.1 ± 0.9	0 ± 1	-158.4
1.1.01.02.	Melanocortin-4 receptor model (active state) with agonist NDP-MSH	2iqr	Homo sapiens	Eukaryo. plasma	1	7	34.5 ± 1.5	18 ± 3	-80.2
1.1.01.02.	TM1-TM2 fragment of fungal STE2 receptor	2k9p	Saccharomyces cerevisiae	Eukaryo. plasma	1	2	31.5 ± 2.0	5 ± 7	-25.7
1.1.01.02.	Melanocortin-4 receptor model (inactive state) with antagonist AGRP	2iqv	Homo sapiens	Eukaryo. plasma	1	7	33.5 ± 1.5	19 ± 3	-75.3
1.1.01.02.	Opsin, retinal-free state	3cap	Bos taurus	Eukaryo. plasma	1	7	31.4 ± 1.3	6 ± 4	-86.0
1.1.01.02.	Mu-opioid receptor model in active state with agonist	2iqo	Rattus norvegicus	Eukaryo. plasma	1	7	35.3 ± 1.6	1 ± 4	-95.7
1.1.01.02.	Rhodopsin	1gzm	Bos taurus	Eukaryo. plasma	1	7	32.4 ± 1.7	8 ± 3	-91.3
1.1.01.02.	Mu-opioid receptor model (inactive state) with antagonist	2iql	Rattus norvegicus	Eukaryo. plasma	1	7	35.0 ± 1.0	9 ± 3	-97.7
1.1.01.02.	Squid rhodopsin dimer	2z73	Todarodes pacificus	Eukaryo. plasma	2	14	33.5 ± 1.1	0 ± 2	-167.5
1.1.01.02.	Beta2-adrenergic receptor	2rh1	Homo sapiens	Eukaryo. plasma	1	7	31.4 ± 1.3	8 ± 3	-84.3
1.1.01.02.	Cholecystokinin A receptor fragment	1d6g	Homo sapiens	Eukaryo. plasma	2	0	8.0 ± 0.8	89 ± 7	-16.1
1.1.01.02.	Beta1-adrenergic receptor	2vt4	Meleagris gallopavo	Eukaryo. plasma	1	7	32.7 ± 1.5	6 ± 4	-95.7
1.1.01.02.	Rhodopsin, a photobleached state	2i37	Bos taurus	Eukaryo. plasma	1	7	31.9 ± 1.4	5 ± 4	-88.6
1.1.01.02.	Opsin, complex with C-terminal peptide of Galpha subunit of transducin	3dqb	Bos taurus	Eukaryo. plasma	1	7	31.5 ± 1.4	6 ± 3	-86.3
1.1.01.02.	Rhodopsin, a dimer	2i36	Bos taurus	Eukaryo. plasma	2	14	30.5 ± 1.4	0 ± 1	-161.5
1.1.01.02.	A2A adenosine receptor bound to antagonist ZM241385	3eml	Homo sapiens	Eukaryo. plasma	1	7	33.2 ± 2.2	8 ± 4	-85.1