Superfamily » 2.4.07. PX domain (1 family) <a href="http://pfam.sanger.ac.uk/family/PF00787" class="external" target="_blank">PF00787</a>, <a href="http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPfamStr.pl?pfam_id=PF00787" class="external" target="_blank">PDBsum</a> - Orientations of Proteins in Membranes (OPM) database

Type:2. Monotopic/peripheral (4 classes)
Class:2.4. Alpha + Beta monotopic/peripheral (50 superfamilies)
Superfamily:2.4.07. PX domain (1 family) PF00787, PDBsum
Family:
1. 2.4.07.01.
  PX domain PF00787, PDBsum
  Bud emergence protein 1
  
  Saccharomyces cerevisiae
  (2v6v, 2czo)
  
  NADPH oxidase organizer 1, PX domain
  
  Homo sapiens
  (2l73)
  
  Nischarin
  
  Homo sapiens
  (3p0c)
  
  PX domain of C2alpha-PI3 kinase
  
  Homo sapiens
  (2ar5, 2iwl, 2rea, 2red)
  
  PX domain of NADH oxidase (p40phox), ligand-bound
  
  Homo sapiens
  (1h6h, 2dyb)
  
  PX domain of NADH oxidase (p47phox), ligand-bound
  
  Homo sapiens
  (1o7k, 1gd5, 1kq6)
  
  PX domain of NADH oxidase (p47phox), ligand-free, longer chain
  
  Homo sapiens
  (1kq6, 1gd5, 1o7k)
  
  PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide
  
  Homo sapiens
  (2wwe)
  
  PX domain of serine/threonine-protein kinase Sgk3
  
  Homo sapiens
  (1xte, 1xtn)
  
  PX domain of sorting nexin GRD19, ligand-bound
  
  Saccharomyces cerevisiae
  (1ocu, 1ocs)
  
  PX domain of sorting nexin GRD19, ligand-free
  
  Saccharomyces cerevisiae
  (1ocs, 1ocu)
  
  PX domain of sorting nexin-17 (SNX17)
  
  Homo sapiens
  (3fog, 3lui)
  
  PX domain of vacuolar morphogenesis protein VAM7
  
  Saccharomyces cerevisiae
  (1kmd)
  
  Sorting nexin-11, conformation 1
  
  Homo sapiens
  (4ikb)
  
  Sorting nexin-11, conformation 2
  
  Homo sapiens
  (4ikd)
  
  Sorting nexin-23 (Kinesin-like protein KIF16B)
  
  Homo sapiens
  (2v14)
  
  Sorting nexin-5
  
  Rattus norvegicus
  (3hpc, 3hpb)

2.4.07. PX domain (1 family) PF00787, PDBsum (17 proteins)

Family	Protein Name	PDB ID	Species	Localization	Num. Subunits	Hydrophobic Thickness or Depth (Å)	Tilt Angle (°)	ΔG_transfer (kcal/mol)
2.4.07.01.	PX domain of C2alpha-PI3 kinase	2ar5	Homo sapiens	Eukaryo. plasma	1	5.6 ± 0.9	83 ± 17	-3.7
2.4.07.01.	PX domain of NADH oxidase (p47phox), ligand-free, longer chain	1kq6	Homo sapiens	Endosome	1	2.4 ± 1.6	88 ± 12	-4.6
2.4.07.01.	PX domain of vacuolar morphogenesis protein VAM7	1kmd	Saccharomyces cerevisiae	Vacuole	1	3.4 ± 1.2	76 ± 8	-7.8
2.4.07.01.	Bud emergence protein 1	2v6v	Saccharomyces cerevisiae	Eukaryo. plasma	1	2.1 ± 1.2	75 ± 6	-5.1
2.4.07.01.	PX domain of sorting nexin GRD19, ligand-bound	1ocu	Saccharomyces cerevisiae	Endosome	2	15.3 ± 0.8	88 ± 6	-34.9
2.4.07.01.	NADPH oxidase organizer 1, PX domain	2l73	Homo sapiens	Eukaryo. plasma	1	2.8 ± 1.9	72 ± 13	-5.1
2.4.07.01.	PX domain of sorting nexin GRD19, ligand-free	1ocs	Saccharomyces cerevisiae	Endosome	1	2.5 ± 1.1	88 ± 11	-5.4
2.4.07.01.	Sorting nexin-11, conformation 1	4ikb	Homo sapiens	Eukaryo. plasma	1	5.2 ± 2.7	61 ± 8	-6.1
2.4.07.01.	PX domain of serine/threonine-protein kinase Sgk3	1xte	Homo sapiens	Endosome	1	1.2 ± 1.4	77 ± 11	-2.9
2.4.07.01.	Sorting nexin-11, conformation 2	4ikd	Homo sapiens	Eukaryo. plasma	1	3.0 ± 1.2	58 ± 4	-5.3
2.4.07.01.	PX domain of sorting nexin-17 (SNX17)	3fog	Homo sapiens	Endosome	1	3.4 ± 1.0	69 ± 12	-4.9
2.4.07.01.	PX domain of Phosphoinositide-3-kinase, class 2, gamma polypeptide	2wwe	Homo sapiens	Golgi	1	2.5 ± 1.3	56 ± 16	-4.8
2.4.07.01.	Sorting nexin-5	3hpc	Rattus norvegicus	Endosome	1	0.0 ± 2.1	90 ± 8	-2.4
2.4.07.01.	PX domain of NADH oxidase (p40phox), ligand-bound	1h6h	Homo sapiens	Endosome	1	3.9 ± 2.0	55 ± 14	-6.0
2.4.07.01.	Sorting nexin-23 (Kinesin-like protein KIF16B)	2v14	Homo sapiens	Endosome	1	3.3 ± 3.0	72 ± 14	-5.4
2.4.07.01.	PX domain of NADH oxidase (p47phox), ligand-bound	1o7k	Homo sapiens	Endosome	1	15.2 ± 1.7	60 ± 15	-18.4
2.4.07.01.	Nischarin	3p0c	Homo sapiens	Endosome	1	4.1 ± 0.5	82 ± 13	-7.0