PDB ID or protein name
See list of these PDB codes

1.1.26. APC (Amino acid-Polyamine-organoCation) superfamily (6 families) 2.A.3 (TCDB) CL0062, PDBsum (23 proteins)

Family Protein Name PDB ID Species Localization Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
1.1.26.01. Leucine transporter LeuT, outward-facing substrate-bound conformation 2a65 Aquifex aeolicus Bact. Gram-neg inner 2 28 29.8 ± 0.5 0 ± 0 -157.9
1.1.26.01. Leucine transporter LeuT, inward-facing conformation 3tt3 Aquifex aeolicus Bact. Gram-neg inner 1 12 27.4 ± 1.6 9 ± 0 -89.1
1.1.26.01. Leucine transporter LeuT, outward-facing conformation, from bicelles 4fxz Aquifex aeolicus Bact. Gram-neg inner 2 24 28.0 ± 0.6 0 ± 0 -144.3
1.1.26.01. Leucine transporter LeuT, outward-facing substrate-free conformation 3tt1 Aquifex aeolicus Bact. Gram-neg inner 2 24 28.2 ± 1.2 0 ± 0 -160.8
1.1.26.02. Sodium-hydantoin transporter Mhp1, outward-facing conformation 2jln Mycobacterium liquefaciens Bact. Gram-pos plas. 1 12 29.8 ± 1.5 16 ± 0 -98.9
1.1.26.02. Sodium-hydantoin transporter Mhp1, ligand-bound 2jlo Mycobacterium liquefaciens Bact. Gram-pos plas. 1 12 31.2 ± 0.8 15 ± 0 -96.5
1.1.26.02. Sodium-hydantoin transporter Mhp1, inward-facing conformation 2x79 Mycobacterium liquefaciens Bact. Gram-pos plas. 1 12 30.7 ± 1.1 13 ± 0 -85.0
1.1.26.03. Sodium/sugar symporter vSGLT, substrate-free 2xq2 Vibrio parahaemolyticus Bact. Gram-neg inner 2 30 30.4 ± 0.6 0 ± 0 -162.7
1.1.26.03. Sodium/sugar symporter vSGLT, substrate-bound 3dh4 Vibrio parahaemolyticus Bact. Gram-neg inner 2 30 30.0 ± 0.7 0 ± 0 -184.0
1.1.26.04. L-carnitine/gamma-butyrobetaine antiporter CaiT, open inward-facing conformation 2wsx Escherichia coli Bact. Gram-neg inner 3 42 28.6 ± 0.7 7 ± 0 -212.7
1.1.26.04. L-carnitine/gamma-butyrobetaine antiporter CaiT, open inward-facing conformation 2wsw Proteus mirabilis Bact. Gram-neg inner 3 42 29.8 ± 0.5 0 ± 0 -218.9
1.1.26.04. Glycine betaine transporter BetP, substrate-bound 2wit Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 30.4 ± 1.2 0 ± 0 -198.6
1.1.26.04. Glycine betaine transporter BetP, alternative inward-facing open conformation 3p03 Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 29.8 ± 0.7 1 ± 0 -160.9
1.1.26.04. Glycine betaine transporter BetP, asymmetric trimer, conformation 2 4doj Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 30.0 ± 0.6 0 ± 0 -186.4
1.1.26.04. Glycine betaine transporter BetP, asymmetric trimer, conformation 1 4ain Corynebacterium glutamicum Bact. Gram-pos plas. 3 36 29.8 ± 0.6 0 ± 0 -198.8
1.1.26.04. L-carnitine/gamma-butyrobetaine antiporter CaiT, substrate-bound 3hfx Escherichia coli Bact. Gram-neg inner 3 42 29.8 ± 0.8 0 ± 0 -203.5
1.1.26.05. Amino acid transporter ApcT, inward-facing conformation 3gia Methanococcus jannaschii Archaebac. 1 12 29.9 ± 1.4 11 ± 2 -92.1
1.1.26.05. Arginine/agmatine transporter (AdiC), substrate-bound 3l1l Escherichia coli Bact. Gram-neg inner 2 24 28.8 ± 1.4 2 ± 2 -132.0
1.1.26.05. Arginine/agmatine transporter (AdiC), intermediate conformation 3ob6 Escherichia coli Bact. Gram-neg inner 2 24 29.8 ± 1.4 3 ± 1 -158.7
1.1.26.05. Arginine/agmatine antiporter (AdiC), outward-facing conformation 3h5m Escherichia coli Bact. Gram-neg inner 2 26 29.0 ± 0.8 0 ± 0 -128.9
1.1.26.05. Glutamate/gamma-aminobutyrate antiporter 4dji Escherichia coli Bact. Gram-neg inner 1 12 30.0 ± 1.1 10 ± 1 -98.9
1.1.26.05. Arginine/agmatine antiporter (AdiC), outward-facing conformation 3hqk Salmonella enterica Bact. Gram-neg inner 2 26 29.8 ± 1.0 0 ± 0 -124.6
1.1.26.06. Uracil transporter UraA 3qe7 Escherichia coli Bact. Gram-neg inner 1 14 27.7 ± 1.2 16 ± 0 -79.3