- Type:1. Transmembrane (2 classes)
- Class:1.1. Alpha-helical transmembrane (54 superfamilies)
- Superfamily:1.1.21. Single-helix ATPase regulators (2 families)
- Family:
- 1.1.21.01.Calcium ATPase regulators 1.A.50 (TCDB)
Phospholamban
Sarcolipin
- 1.1.21.02.FXYD regulators 1.A.27 (TCDB)
Na,K-ATPase regulatory protein FXYD1 (phospholemman)
1.1.21. Single-helix ATPase regulators (2 families) (4 proteins)
| Family | Protein Name | PDB ID | Species | Localization | Num. Subunits | Num. TM Sec. Structs. | Hydrophobic Thickness or Depth (Å) | Tilt Angle (°) | ΔGtransfer (kcal/mol) |
|---|---|---|---|---|---|---|---|---|---|
| 1.1.21.01. | Phospholamban | 1zll | Homo sapiens | Endoplasm. reticulum | 5 | 5 | 31.5 ± 1.2 | 0 ± 1 | -91.1 |
| 1.1.21.01. | Sarcolipin | 1jdm | Homo sapiens | Endoplasm. reticulum | 1 | 1 | 28.9 ± 1.8 | 1 ± 7 | -32.1 |
| 1.1.21.02. | Na,K-ATPase regulatory protein FXYD1 (phospholemman) | 2jo1 | Homo sapiens | Endoplasm. reticulum | 1 | 1 | 30.7 ± 2.8 | 8 ± 3 | -34.8 |
| 1.1.21.02. | Na,K-ATPase regulatory protein FXYD1 (phospholemman) | 2jp3 | Rattus norvegicus | Endoplasm. reticulum | 1 | 1 | 32.5 ± 1.0 | 11 ± 6 | -31.2 |
