PDB ID or protein name

Endosome membrane (35 proteins)

Family Protein Name PDB ID Species Num. Subunits Num. TM Sec. Structs. Hydrophobic Thickness or Depth (Å) Tilt Angle (°) ΔGtransfer (kcal/mol)
2.4.07.01. PX domain of sorting nexin GRD19, ligand-bound 1ocu Saccharomyces cerevisiae 2 0 15.3 ± 0.8 88 ± 6 -34.9
2.2.26.01. Early endosome antigen 1 (EEA1), model of dimer with lipids 1joc Homo sapiens 2 0 15.0 ± 0.4 2 ± 11 -34.0
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-bound 1o7k Homo sapiens 1 0 15.2 ± 1.7 60 ± 15 -18.4
3.1.07.01. Fusion peptide (512-541) of protein gp41 2ari Human immunodeficiency virus type 1 1 0 10.0 ± 1.0 88 ± 9 -16.1
2.3.06.10. vitellogenin 3d59 Dendroaspis polylepis polylepis (Black mamba) 1 0 5.5 ± 1.2 87 ± 10 -13.6
3.1.07.02. Juxtamembrane peptide (662-683) of protein gp41 2pv6 Human immunodeficiency virus type 1 1 0 6.7 ± 0.6 82 ± 2 -13.5
3.1.07.01. Fusion peptide (510-532) of protein gp41 2pjv Human immunodeficiency virus type 1 1 0 8.7 ± 3.8 64 ± 4 -10.9
3.1.07.05. Non-structural polyprotein, membrane-bound domain 1fw5 Semiliki forest virus 1 0 7.9 ± 1.5 73 ± 17 -10.2
3.1.07.02. Peptide of envelope glycoprotein H (625-644) 2lqy Human herpesvirus 1 0 3.2 ± 0.8 88 ± 5 -10.2
3.1.07.02. Juxtamembrane peptide (684-719) of protein gp41 2kzq Hepatitis C virus 1 0 4.3 ± 3.3 88 ± 0 -9.9
3.1.07.01. Fusion peptide (517-539) of protein gp41 1p5a Human immunodeficiency virus type 1 1 1 25.8 ± 5.5 12 ± 3 -9.3
3.1.07.02. Juxtamembrane peptide (665-683) of protein gp41 1jau Human immunodeficiency virus type 1 1 0 4.0 ± 4.2 86 ± 2 -8.0
2.3.16.04. EH domain-containing protein 2 2qpt Mus musculus 2 0 4.5 ± 2.1 20 ± 14 -7.8
2.4.07.01. Nischarin 3p0c Homo sapiens 1 0 4.1 ± 0.5 82 ± 13 -7.0
3.1.07.01. Fusion peptide from E1 envelope glycoprotein 2rsw Chikungunya virus 1 0 8.3 ± 0.6 57 ± 7 -6.9
2.1.15.02. Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) 1dvp Drosophila melanogaster 2 0 3.0 ± 0.0 89 ± 0 -6.6
2.4.07.01. PX domain of NADH oxidase (p40phox), ligand-bound 1h6h Homo sapiens 1 0 3.9 ± 2.0 55 ± 14 -6.0
3.1.07.04. Juxtamembrane peptide of hepatis C virus E1 glycoprotein (314-342) 2knu Hepatitis C virus 1 0 5.3 ± 0.9 82 ± 6 -5.9
2.2.29.01. Multivesicular body subunit 12B 3tow Homo sapiens 1 0 4.5 ± 2.3 33 ± 22 -5.8
2.4.07.01. PX domain of sorting nexin GRD19, ligand-free 1ocs Saccharomyces cerevisiae 1 0 2.5 ± 1.1 88 ± 11 -5.4
2.4.07.01. Sorting nexin-23 (Kinesin-like protein KIF16B) 2v14 Homo sapiens 1 0 3.3 ± 3.0 72 ± 14 -5.4
2.3.16.07. Ras-related protein Rab-7a 1vg8 Rattus norvegicus 1 0 1.7 ± 0.5 74 ± 3 -5.3
2.4.06.01. Lipid transport protein Mln64 (StARD3) 1em2 Homo sapiens 1 0 2.0 ± 1.1 82 ± 12 -5.0
2.4.07.01. PX domain of sorting nexin-17 (SNX17) 3fog Homo sapiens 1 0 3.4 ± 1.0 69 ± 12 -4.9
2.4.07.01. PX domain of NADH oxidase (p47phox), ligand-free, longer chain 1kq6 Homo sapiens 1 0 2.4 ± 1.6 88 ± 12 -4.6
2.1.29.06. Perilipin-3 1szi Mus musculus 1 0 2.4 ± 2.3 61 ± 6 -4.1
2.1.21.03. Matrix protein p15 1mn8 Moloney murine leukemia virus 1 0 1.5 ± 1.8 65 ± 24 -3.5
2.2.26.01. Early endosome antigen 1 (EEA1), monomer 1hyi Homo sapiens 1 0 3.0 ± 2.0 24 ± 17 -3.5
2.2.26.01. LM-5 FYVE domain 1z2q Leishmania major 1 0 1.5 ± 1.5 22 ± 19 -3.4
2.2.20.01. Myosin X 3tfm Rattus norvegicus 1 0 1.5 ± 2.6 81 ± 5 -3.0
2.4.07.01. PX domain of serine/threonine-protein kinase Sgk3 1xte Homo sapiens 1 0 1.2 ± 1.4 77 ± 11 -2.9
2.2.26.01. RUN and FYVE domain-containing protein 1 2yw8 Homo sapiens 1 0 0.7 ± 3.4 48 ± 38 -2.8
2.3.16.06. ADP-ribosylation factor-like protein 8A 2h18 Homo sapiens 1 0 1.2 ± 3.6 58 ± 28 -2.6
2.1.21.05. Matrix protein p15 1hek Equine infectious anemia virus 1 0 1.0 ± 2.8 76 ± 21 -2.6
2.4.07.01. Sorting nexin-5 3hpc Rattus norvegicus 1 0 0.0 ± 2.1 90 ± 8 -2.4