PDB ID or protein name

1ae7 » Snake phospholipase A2, group I

1ae7 » Snake phospholipase A2, group I
Magnify 1ae7 » Snake phospholipase A2, group IEnlarged view of image
3D view in Jmol or Webmol

gray dot

Download Coordinates

gray dot

Topology in Secreted
Topologyout side
in side
1ae7 » Snake phospholipase A2, group I
Depth 4.7 ± 0.6 Å
Tilt Angle 84 ± 9°
ΔGtransfer -6.2 kcal/mol
Links to 1ae7 PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology out
Resolution 2.0 Å
Other PDB entries representing this structure 4e4c
Number of subunits 1
Comments on 1ae7 » Snake phospholipase A2, group I
Inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini. Acts presynaptically. Is directly toxic to skeletal muscle upon local application in vivo (dystrophic effect).