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• Protein Classification

• Types (3 types)
• Classes (11 classes)
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• Species (538 species)
• Localization (24 types)
• All proteins in OPM (2172 proteins)

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1ae7 » Snake phospholipase A2, group I

• Type: 2. Monotopic/peripheral (4 classes)
• Class: 2.1. All alpha monotopic/peripheral (60 superfamilies)
• Superfamily: 2.1.01. Secretory phospholipase A2 (4 families)
• Family: 2.1.01.01. Vertebrate secretory phospholipase A2 (58 proteins)
• Species: Notechis scutatus scutatus (1 protein)
• Localization: Secreted (681 proteins)

1ae7 » Snake phospholipase A2, group I
Depth	4.7 ± 0.6 Å
Tilt Angle	84 ± 9°
ΔGtransfer	-6.2 kcal/mol
Links to 1ae7	PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology	out
Resolution	2.0 Å
Other PDB entries of this protein	none
Number of subunits	1

Comments on 1ae7 » Snake phospholipase A2, group I
Inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini. Acts presynaptically. Is directly toxic to skeletal muscle upon local application in vivo (dystrophic effect).

Copyright © 2005-2013 Andrei Lomize, Mikhail Lomize and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA