PDB ID or protein name

1akg » alpha-conotoxin PNIB

1akg » alpha-conotoxin PNIB
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Topology in Secreted
Topologyout side
in side
1akg » alpha-conotoxin PNIB
Hydrophobic Thickness or Depth 4.2 ± 1.4 Å
Tilt Angle 42 ± 19°
ΔGtransfer -5.9 kcal/mol
Links to 1akg PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology out
Resolution 1.1 Å
Other PDB entries representing this structure none
Number of subunits 1
Experimental Verification for 1akg » alpha-conotoxin PNIB
Detected membrane-binding site interacts with acetylcholine receptor. See structures of the complexes (2br8 and 2c9t).
Comments on 1akg » alpha-conotoxin PNIB
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.