PDB ID or protein name

1auv » Synapsin I

1auv » Synapsin I
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Topology in Vesicle membrane
Topologylumenal side
cytoplasmic side
1auv » Synapsin I
Depth 1.9 ± 1.1 Å
Tilt Angle 86 ± 11°
ΔGtransfer -5.2 kcal/mol
Links to 1auv PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology cytoplasmic
Resolution 2.1 Å
Other PDB entries representing this structure 1aux, 1pk8, 1px2
Number of subunits 1
Experimental Verification for 1auv » Synapsin I
Membrane-interacting residues have been identified as coming from the regions 166-192, 233-258, or/and 278-327 (Cheetham et al. 2001) in agreement with our results (residues L168, V172, and L297 are buried in the membrane core).
1 reference
Cheetham, J.J., Hilfiker, S., Benfenati, F., Weber, T., Greengard, P., and Czernik, A.J. 2001. Identification of synapsin I peptides that insert into lipid membranes. Biochem. J. 354 (Pt 1): 57-66. PubMed
Comments on 1auv » Synapsin I
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release.