PDB ID or protein name

1cx2 » Prostaglandin H2 synthase-2 (cyclooxygenase)

1cx2 » Prostaglandin H2 synthase-2 (cyclooxygenase)
Magnify 1cx2 » Prostaglandin H2 synthase-2 (cyclooxygenase)Enlarged view of image
3D view in Jmol or Webmol

gray dot

Download Coordinates

gray dot

Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
1cx2 » Prostaglandin H2 synthase-2 (cyclooxygenase)
Depth 9.7 ± 0.4 Å
Tilt Angle 89 ± 3°
ΔGtransfer -37.4 kcal/mol
Links to 1cx2 PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology lumenal
Resolution 3.00 Å
Other PDB entries representing this structure 1cvu, 1ddx, 1pxx, 3hs5, 3hs6, 3hs7, 3krk, 3ln0, 3ln1, 3mdl, 3mqe, 3nt1, 3ntb, 3ntg, 3olt, 3olu, 3pgh, 3q7d, 3qh0, 3qmo, 3rr3, 3tzi, 4cox, 4e1g, 4fm5, 4m10, 4m11, 4otj, 4oty, 4ph9, 4rrw, 4rrx, 4rry, 4rrz, 4rs0, 4rut, 4z0l, 5cox, 5jvy, 5jw1, 6cox
Number of subunits 2
Experimental Verification for 1cx2 » Prostaglandin H2 synthase-2 (cyclooxygenase)
Crystallization with detergent (N-OCTYL-beta-D-GLUCOPYRANOSIDE).
Comments on 1cx2 » Prostaglandin H2 synthase-2 (cyclooxygenase)
May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.