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• Protein Classification

• Types (3 types)
• Classes (11 classes)
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1dg2 » alpha-conotoxin auIB

• Type: 3. Peptides (4 classes)
• Class: 3.1. Alpha-helical peptides (32 superfamilies)
• Superfamily: 3.1.20. Alpha-conotoxins (1 family)
• Family: 3.1.20.01. Alpha-conotoxin (18 proteins)
• Species: Conus aulicus (1 protein)
• Localization: Secreted (681 proteins)

1dg2 » alpha-conotoxin auIB
Hydrophobic Thickness or Depth	5.1 ± 1.7 Å
Tilt Angle	89 ± 16°
ΔGtransfer	-4.9 kcal/mol
Links to 1dg2	PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology	out
Resolution	NMR
Other PDB entries of this protein	1mxn, 1mxp
Number of subunits	1

Experimental Verification for 1dg2 » alpha-conotoxin auIB
Detected membrane-interaction site is also involved in protein-protein binding. See complexes of other conotoxins with acetylcholine receptor (2br8 and 2c9t).

Comments on 1dg2 » alpha-conotoxin auIB
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.

Copyright © 2005-2013 Andrei Lomize, Mikhail Lomize and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA