PDB ID or protein name

1dt6 » Cytochrome P450 2C5, different conformation

1dt6 » Cytochrome P450 2C5, different conformation
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
1dt6 » Cytochrome P450 2C5, different conformation
Hydrophobic Thickness 7.3 ± 1.0 Å
Tilt Angle 13 ± 7°
ΔGtransfer -8.8 kcal/mol
Links to 1dt6 PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology cytoplasmic
Resolution 3.0 Å
Other PDB entries representing this structure none
Number of TM subunits 1
Comments on 1dt6 » Cytochrome P450 2C5, different conformation
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This protein differs from other forms of cytochrome P450 in that it catalyzes the 21-hydroxylation of progesterone, resulting in the formation of deoxycorticosterone.