PDB ID or protein name

1etn » Heat-stable enterotoxin ST-IA/ST-P

1etn » Heat-stable enterotoxin ST-IA/ST-P
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Topology in Secreted
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1etn » Heat-stable enterotoxin ST-IA/ST-P
Hydrophobic Thickness or Depth 3.0 ± 3.7 Å
Tilt Angle 33 ± 39°
ΔGtransfer -2.1 kcal/mol
Links to 1etn PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology out
Resolution 0.8 Å
Other PDB entries representing this structure 1etl, 1etm
Number of subunits 1
Comments on 1etn » Heat-stable enterotoxin ST-IA/ST-P
Enterotoxin binds to a membrane-associated guanylyl cyclase C which is located on intestinal epithelial cell membranes. Prokaryotic heat-stable enterotoxins are responsible for acute diarrhea.