PDB ID or protein name

1gyg » Alpha-toxin (PHLC1_CLOPE), closed state (inactive)

1gyg » Alpha-toxin (PHLC1_CLOPE), closed state (inactive)
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1gyg » Alpha-toxin (PHLC1_CLOPE), closed state (inactive)
Depth 6.1 ± 2.0 Å
Tilt Angle 75 ± 6°
ΔGtransfer -5.9 kcal/mol
Links to 1gyg PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology out
Resolution 1.9 Å
Other PDB entries representing this structure none
Number of subunits 1
Experimental Verification for 1gyg » Alpha-toxin (PHLC1_CLOPE), closed state (inactive)
Results are consistent with the important role of Y331 and F334 for asociation with lipid bilayers (Jepson et al. 2001).
1 reference
Jepson M, Bullifent HL, Crane D, Flores-Diaz M, Alape-Giron A, Jayasekeera P, Lingard B, Moss D, Titball RW. 2001. Tyrosine 331 and phenylalanine 334 in Clostridium perfringens alpha-toxin are essential for cytotoxic activity. FEBS Lett. 495:172-7. PubMed