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1iou » Synaptobrevin homolog 1

• Type: 1. Transmembrane (3 classes)
• Class: 1.2. Alpha-helical bitopic (42 superfamilies)
• Superfamily: 1.2.17. SNARE complex (3 families) 1.F.1 (TCDB)
• Family: 1.2.17.02. Synatpobrevin (2 proteins)
• Species: Saccharomyces cerevisiae (41 proteins)
• Localization: Eukaryotic plasma membrane (479 proteins)

1iou » Synaptobrevin homolog 1
Hydrophobic Thickness	3.4 ± 1.1 Å
Tilt Angle	79 ± 12°
ΔGtransfer	-6.0 kcal/mol
Links to 1iou	PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology	cytoplasmic
Resolution	NMR
Other PDB entries of this protein	1h8m
Number of TM subunits	1

Experimental Verification for 1iou » Synaptobrevin homolog 1
This is a membrane-assocuiated protein. Location of S-farnesyl cysteine 197 (at the end of v-SNARE doain) is compatible with the calculated orientation. Orientations of this domain here and in the signal recognition particle alpha-beta complex (1nrj) are similar.

Comments on 1iou » Synaptobrevin homolog 1
This is structure of longin domain (3-140). It does not include v-SNARE coiled-coil homology domain (residues 140-200).

Copyright © 2005-2013 Andrei Lomize, Mikhail Lomize and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA