PDB ID or protein name

1joc » Early endosome antigen 1 (EEA1), model of dimer with lipids

1joc » Early endosome antigen 1 (EEA1), model of dimer with lipids
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Topology in Endosome membrane
Topologylumenal side
cytoplasmic side
1joc » Early endosome antigen 1 (EEA1), model of dimer with lipids
Depth 15.0 ± 0.4 Å
Tilt Angle 2 ± 11°
ΔGtransfer -34.0 kcal/mol
Links to 1joc PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology cytoplasmic
Resolution 2.2 Å
Other PDB entries representing this structure none
Number of subunits 2
Experimental Verification for 1joc » Early endosome antigen 1 (EEA1), model of dimer with lipids
This is calculation with bound lipids. Acyl chains of two lipids were modelled. Calculated hydrocarbon boundary of the lipid bilayer corresponds to the carbonyl groups of the bound lipid. Depending on conformations of bound lipids, the protein can penetrate deeper by ~2 A. Results for the dimer without bound lipids are exactly the same as for lipid-free EEA1 monomer (1hyi). Transfer energy was calculated without contribution from the bound lipid.