PDB ID or protein name

1joh » Antiamoebin I

1joh » Antiamoebin I
Magnify 1joh » Antiamoebin IEnlarged view of image
3D view in Jmol or Webmol

gray dot

Download Coordinates

gray dot

Topology in Secreted
Topologyout side
in side
1joh » Antiamoebin I
Hydrophobic Thickness or Depth 8.1 ± 0.8 Å
Tilt Angle 82 ± 5°
ΔGtransfer -11.7 kcal/mol
Links to 1joh PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology out
Resolution 1.4 Å
Other PDB entries representing this structure 1gq0, 2m1f
Number of subunits 1
Experimental Verification for 1joh » Antiamoebin I
Orientation and membrane penetration depth are consistent with fluorescence quenching studies (Kropacheva et al. 2005).
1 reference
Kropacheva, T.N., Salnikov, E.S., Nguyen, H.H., Reissmann, S., Yakimenko, Z.A., Tagaev, A.A., Ovchinnikova, T.V., and Raap, J. 2005. Membrane association and activity of 15/16-membered peptide antibiotics: zervamicin IIB, ampullosporin A and antiamoebin I PubMed
Comments on 1joh » Antiamoebin I
There are small energetic differences between the surface and transmembrane arrangements of the peptide. The shown arrangement has the lowest transfer energy.