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1jza » Neurotoxin 2

• Type: 2. Monotopic/peripheral (4 classes)
• Class: 2.4. Alpha + Beta monotopic/peripheral (50 superfamilies)
• Superfamily: 2.4.16. Scorpion toxin-like knottin (11 families)
• Family: 2.4.16.01. Long-chain scorpion toxins (25 proteins) 8.B.1 (TCDB)
• Species: Centruroides sculpturatus (Bark scorpion) (6 proteins)
• Localization: Secreted (681 proteins)

1jza » Neurotoxin 2
Depth	4.0 ± 1.7 Å
Tilt Angle	68 ± 15°
ΔGtransfer	-5.6 kcal/mol
Links to 1jza	PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology	out
Resolution	2.2 Å
Other PDB entries of this protein	1jzb
Number of subunits	1

Comments on 1jza » Neurotoxin 2
Membrane-binding site participates in protein-protein interaction. Binds to sodium channels and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.

Copyright © 2005-2013 Andrei Lomize, Mikhail Lomize and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA