PDB ID or protein name

1lcy » Mitochondrial serine protease HtrA2

1lcy » Mitochondrial serine protease HtrA2
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Topology in Mitochondrial inner membrane
Topologyintermembrane space side
matrix space side
1lcy » Mitochondrial serine protease HtrA2
Depth 7.4 ± 1.8 Å
Tilt Angle 67 ± 14°
ΔGtransfer -5.1 kcal/mol
Links to 1lcy PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology intermembrane space
Resolution 2.0 Å
Other PDB entries representing this structure none
Number of subunits 1
Experimental Verification for 1lcy » Mitochondrial serine protease HtrA2
No experimental data about membrane-protein association. Predicted membrane-association site may interact with another protein.
Comments on 1lcy » Mitochondrial serine protease HtrA2
Serine protease that shows proteolytic activity against a nonspecific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs). Includes PDZ domain.