- Protein Classification
- Protein Links
 | lumenal side |
| cytoplasmic side |
| 1mt5 » Fatty acid amide hydrolase | |
|---|---|
| Depth | 11.1 ± 0.2 Å |
| Tilt Angle | 89 ± 0° |
| ΔGtransfer | -21.9 kcal/mol |
| Links to 1mt5 | PDB Sum, PDB, SCOP, MSD, OCA, MMDB |
| Topology | cytoplasmic |
| Resolution | 2.80 Å |
| Other PDB entries representing this structure | 2vya, 2wap, 2wj1, 2wj2, 3k7f, 3k83, 3k84, 3lj6, 3lj7, 3oj8, 3ppm, 3pr0, 3qj8, 3qj9, 3qk5, 3qkv, 4do3, 4hbp, 4j5p |
| Number of subunits | 2 |
| Experimental Verification for 1mt5 » Fatty acid amide hydrolase |
|---|
| Consistent with membrane-association mode proposed by Bracey et al. (2002). The protein has TM helix 9-29 (Patricelli et al. 1998), in agreement with this orientation. |
| 2 references |
|---|
| Bracey MH, Hanson MA, Masuda KR, Stevens RC, Cravatt BF. 2002. Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling. Science. 298:1793-6. PubMed |
| Patricelli MP, Lashuel HA, Giang DK, Kelly JW, Cravatt BF. 1998. Comparative characterization of a wild type and transmembrane domain-deleted fatty acid amide hydrolase: identification of the transmembrane domain as a site for oligomerization. Biochemistry. 37: 15177-15187. PubMed |
