- Protein Classification
- Protein Links
| 1nb1 » Kalata B1, segment 93-120 | |
|---|---|
| Depth | 5.3 ± 1.4 Å |
| Tilt Angle | 81 ± 18° |
| ΔGtransfer | -5.5 kcal/mol |
| Links to 1nb1 | PDB Sum, PDB, SCOP, MSD, OCA, MMDB |
| Topology | out |
| Resolution | NMR |
| Other PDB entries of this protein | 1jjz, 1k48, 1kal, 1n1u, 1orx, 1znu, 2f2i, 2f2j, 2jue, 2khb |
| Number of subunits | 1 |
| Experimental Verification for 1nb1 » Kalata B1, segment 93-120 |
|---|
| Residues buried in the membrane core: W19-V21 and L27-V29 (based on locations of NH hydrogens). This is consistent with burial of loops W19-V21 and L27-V29 in DPC micelles (Shenkarev et al. 2006). Maximal membrane binding affinity is -6.4 kcal/mol (Kamimori et al. 2005). |
| 2 references |
|---|
| Kamimori, H., Hall, K., Craik, D.J., and Aguilar, M.I. 2005. Studies on the membrane interactions of the cyclotides kalata B1 and kalata B6 on model membrane systems by surface plasmon resonance. Anal. Biochem. 337:149-153. PubMed |
| Shenkarev ZO, Nadezhdin KD, Sobol VA, Sobol AG, Skjeldal L, Arseniev AS. 2006. Conformation and mode of membrane interaction in cyclotides. FEBS J. 273: 2658-2672. PubMed |
| Comments on 1nb1 » Kalata B1, segment 93-120 |
|---|
| Probably participates in a plant defense mechanism. Has antibiotic activity. |
