- Protein Classification
- Protein Links
 | lumenal side |
| cytoplasmic side |
| 1ocu » PX domain of sorting nexin GRD19, ligand-bound | |
|---|---|
| Depth | 15.3 ± 0.8 Å |
| Tilt Angle | 88 ± 6° |
| ΔGtransfer | -34.9 kcal/mol |
| Links to 1ocu | PDB Sum, PDB, SCOP, MSD, OCA, MMDB |
| Topology | cytoplasmic |
| Resolution | 2.3 Å |
| Other PDB entries representing this structure | 1ocs |
| Number of subunits | 2 |
| Experimental Verification for 1ocu » PX domain of sorting nexin GRD19, ligand-bound |
|---|
| This position was calculated for the complex with bound lipid. Lipid acyl chains were modelled. Calculated hydrocarbon boundary of the lipid bilayer corresponds to the carbonyl groups of the bound lipid. Spatial positions of the protein calculated with and without the bound lipid are almost identical. Transfer energy was calculated without contribution from the bound lipid. |
| 1 reference |
|---|
| Cho W, Stahelin RV. 2005. Membrane-protein interactions in cell signaling and membrane trafficking. Annu Rev Biophys Biomol Struct. 34:119-51. PubMed |
| Comments on 1ocu » PX domain of sorting nexin GRD19, ligand-bound |
|---|
| Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Subcellular localization of PX domains - see Cho and Stahelin (2005). |
