PDB ID or protein name

1oiz » Alpha-tocopherol transfer protein, open state

1oiz » Alpha-tocopherol transfer protein, open state
Magnify 1oiz » Alpha-tocopherol transfer protein, open stateEnlarged view of image
3D view in Jmol or Webmol

gray dot

Download Coordinates

gray dot

Topology in Golgi membrane
Topologylumenal side
cytoplasmic side
1oiz » Alpha-tocopherol transfer protein, open state
Depth 8.1 ± 1.0 Å
Tilt Angle 64 ± 10°
ΔGtransfer -17.6 kcal/mol
Links to 1oiz PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology cytoplasmic
Resolution 1.8 Å
Other PDB entries representing this structure none
Number of subunits 1
Experimental Verification for 1oiz » Alpha-tocopherol transfer protein, open state
Consistent with membrane-association mode discussed by Meier et al. (2003).
1 reference
Meier R, Tomizaki T, Schulze-Briese C, Baumann U, Stocker A. 2003. The molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer protein. J Mol Biol. 331: 725-734. PubMed
Comments on 1oiz » Alpha-tocopherol transfer protein, open state
Open state was formed in the presence of detergent: molecules of TRITON X-100 penetrate between "entrance" alpha-helices. This protein binds alpha-tocopherol and enhances its transfer between separate membranes.