PDB ID or protein name

1ok8 » Envelope glycoprotein, Dengue virus type 2, structure 1

1ok8 » Envelope glycoprotein, Dengue virus type 2, structure 1
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Topology in Viral membrane
Topologyout side
in side
1ok8 » Envelope glycoprotein, Dengue virus type 2, structure 1
Hydrophobic Thickness 5.2 ± 0.9 Å
Tilt Angle 0 ± 6°
ΔGtransfer -9.5 kcal/mol
Links to 1ok8 PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology out
Resolution 2.0 Å
Other PDB entries representing this structure 1oan, 1oke, 1p58, 1tg8, 1tge, 1thd
Number of TM subunits 3
Experimental Verification for 1ok8 » Envelope glycoprotein, Dengue virus type 2, structure 1
Corresponds to host-cell membrane association mode proposed by Modis et al. (2004). Crystallized with detergent (N-UNDECYL-beta-D-MALTOPYRANOSIDE/ N-NONYL-beta-D-GLUCOPYRANOSIDE).
1 reference
Modis Y, Ogata S, Clements D, Harrison SC. 2004. Structure of the dengue virus envelope protein after membrane fusion. Nature. 427: 313-319. PubMed
Comments on 1ok8 » Envelope glycoprotein, Dengue virus type 2, structure 1
Calculated orientation reflects association with host-cell membrane rather than with viral membrane. TM helices at the opposite side of the trimer (not present in the crystal structure) are anchored in viral membrane.