PDB ID or protein name

1oxw » Patatin

1oxw » Patatin
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Topology in Secreted
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1oxw » Patatin
Depth 3.9 ± 2.0 Å
Tilt Angle 28 ± 11°
ΔGtransfer -6.5 kcal/mol
Links to 1oxw PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology out
Resolution 2.2 Å
Other PDB entries representing this structure none
Number of subunits 1
1 reference
Rydel TJ, Williams JM, Krieger E, Moshiri F, Stallings WC, Brown SM, Pershing JC, Purcell JP, Alibhai MF. 2003. The crystal structure, mutagenesis, and activity studies reveal that patatin is a lipid acyl hydrolase with a Ser-Asp catalytic dyad. Biochemistry. 42:6696-708. PubMed
Comments on 1oxw » Patatin
Patatin is a nonspecific lipid acyl hydrolase that accounts for approximately 40% of the total soluble protein in mature potato tubers, and it has potent insecticidal activity against the corn rootworm. It has a Ser-Asp catalytic dyad and an active site like that in human cytosolic phospholipase A2 (Rydel et al. 2003).