PDB ID or protein name

1p4u » ADP-ribosylation factor binding protein Gga3 domain

1p4u » ADP-ribosylation factor binding protein Gga3 domain
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Topology in Golgi membrane
Topologylumenal side
cytoplasmic side
1p4u » ADP-ribosylation factor binding protein Gga3 domain
Depth 6.5 ± 1.1 Å
Tilt Angle 71 ± 11°
ΔGtransfer -6.5 kcal/mol
Links to 1p4u PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology cytoplasmic
Resolution 2.2 Å
Other PDB entries representing this structure none
Number of subunits 1
Experimental Verification for 1p4u » ADP-ribosylation factor binding protein Gga3 domain
No direct experimental data about interactions of this specific domain with lipid bilayers. The predicted membrane binding site may be also involved in protein-protein interactions.
Comments on 1p4u » ADP-ribosylation factor binding protein Gga3 domain
Membrane-associated. Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. The GAE domain binds accessory proteins regulating GGAs function.