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• Protein Classification

• Types (3 types)
• Classes (11 classes)
• Superfamilies (392 superfamilies)
• Families (667 families)
• Species (538 species)
• Localization (24 types)
• All proteins in OPM (2172 proteins)

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1qd6 » Outer membrane phospholipase A

• Type: 1. Transmembrane (3 classes)
• Class: 1.3. Beta-barrel transmembrane (26 superfamilies)
• Superfamily: 1.3.12. OM phospholipase (n=12,S=16) (1 family)
• Family: 1.3.12.01. OM phospholipase A, OmpLA (2 proteins)
• Species: Escherichia coli (178 proteins)
• Localization: Bacterial Gram-negative outer membrane (136 proteins)

1qd6 » Outer membrane phospholipase A
Hydrophobic Thickness	23.9 ± 1.0 Å
Tilt Angle	0 ± 0°
ΔGtransfer	-77.2 kcal/mol
Links to 1qd6	PDB Sum, PDB, SCOP, MSD, OCA, MMDB
Topology	subunit C (N-terminus in)
Resolution	2.10 Å
Other PDB entries of this protein	1fw2, 1fw3, 1ild, 1ilz, 1im0, 1qd5
Number of TM Secondary Structures	12

2 transmembrane subunits
C - Tilt: 9° - Segments: 1(38-43), 2(67-78), 3(87-96), 4(113-122), 5(135-143), 6(155-164), 7(169-179), 8(195-201), 9(206-215), 10(221-232), 11(235-243), 12(259-264)
D - Tilt: 8° - Segments: 1(38-43), 2(67-78), 3(87-96), 4(113-122), 5(135-143), 6(156-164), 7(169-179), 8(195-201), 9(206-214), 10(222-230), 11(235-243), 12(259-264)

Experimental Verification for 1qd6 » Outer membrane phospholipase A
Membrane boundary planes of monomeric form (1qd6C OPM entry) are consistent with detergent-covered region in crystals of monomeric phospholipase A (Snijder et al. 2003).

1 reference
Snijder HJ, Timmins PA, Kalk KH, and Dijkstra BW (2003) Detergent organization in crystals of monomeric outer membrane phospholipase A. J. Struct. Biol. 141: 122-131. PubMed

Copyright © 2005-2013 Andrei Lomize, Mikhail Lomize and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA